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The map label for this gene is gsiD [H]

Identifier: 99079877

GI number: 99079877

Start: 37516

End: 38433

Strand: Reverse

Name: gsiD [H]

Synonym: TM1040_0036

Alternate gene names: 99079877

Gene position: 38433-37516 (Counterclockwise)

Preceding gene: 99079878

Following gene: 99079876

Centisome position: 1.2

GC content: 61.66

Gene sequence:

>918_bases
ATGAGCAGCCAGACCATGACACTTCGAGAGTGGCTCTTGACGGATACGCCAACGTCGCGCCGTCAGGCCAGGCTGGCCGC
CTATTACAAAGGCTGGCTAACCTTACGGTCCAACCATATGGCGATGGGGGGGCTGGCAATCATCGTTCTGCTCGTCGCCG
TTGCGATCTTTGCACCGCTTCTTGCGCCTCATGATCCCTACTATCAGGATCTTGGCAATCGGCTTCAGCCCCTGGGCACC
GAAGGGCACATCCTCGGCACCGACTCGCTGGGGCGGGACATCCTGAGCCGCCTCATCTGGGGCGCACGGATCACGCTCTA
CATCGTCGCACTTGTTGCCATGATCGCGCCCATCGTCGGGTTGTTGGTCGGAACGGTCTCCGGCTACGTGGGCGGCTGGG
TCGACATCATGCTGATGCGGGTGACGGATATTTTCCTTGCGTTCCCACGCCTTGTGCTGGCGCTGGCCTTTGTGGCGGCG
CTGGGAGCCGGGATTGAGAACGCAGTGCTGGCGATTTCACTCACGGCCTGGCCCCCCTACGCGCGTCTGGCACGGGCCGA
GACGCTCACCATCCGTTCGTCGGATTTCATCAGCGCGATCCGTCTGCAAGGGGCGGGGCCGCTCCTGATCATCACCAAAC
ATATCTGGCCGCTCTGTATCAGTTCGCTGATCGTGCGGGTGACACTGGATATGGCGGGGATCATTCTGGCGGCTGCGGGA
CTTGGCTTTCTGGGCCTTGGCGCGCAACCTCCAAGCCCGGAATGGGGCGCGATGATCTCCGAGGGGCGCCGGTTCATTCT
GGACTACTGGTGGGTCGCCACCATGCCCGGTCTTGCCATCTTTGCCGTTTCGCTGGCCTTCAACCTTCTGGGCGATGGTT
TGCGCGATGTGCTTGATCCGAAGGATAGCAGCTCATGA

Upstream 100 bases:

>100_bases
TGAACGCCGTGCTTGGTGGCACCGTGGTCGTCGGCCTCGTGTTCATCGTGCTGAACGTTTTTTCCGACCTCCTCTACAAA
GTCTTTGATCCGAGGTCGAA

Downstream 100 bases:

>100_bases
GCACACTTCTGGATATTGAAAACCTCTGGGTGAAGTTCCCGACCCGCAACGGCATCTTTGATGCGGTGCGCGGGGTGAGC
TTCTCGCTTGGAAAAGAACG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSSQTMTLREWLLTDTPTSRRQARLAAYYKGWLTLRSNHMAMGGLAIIVLLVAVAIFAPLLAPHDPYYQDLGNRLQPLGT
EGHILGTDSLGRDILSRLIWGARITLYIVALVAMIAPIVGLLVGTVSGYVGGWVDIMLMRVTDIFLAFPRLVLALAFVAA
LGAGIENAVLAISLTAWPPYARLARAETLTIRSSDFISAIRLQGAGPLLIITKHIWPLCISSLIVRVTLDMAGIILAAAG
LGFLGLGAQPPSPEWGAMISEGRRFILDYWWVATMPGLAIFAVSLAFNLLGDGLRDVLDPKDSSS

Sequences:

>Translated_305_residues
MSSQTMTLREWLLTDTPTSRRQARLAAYYKGWLTLRSNHMAMGGLAIIVLLVAVAIFAPLLAPHDPYYQDLGNRLQPLGT
EGHILGTDSLGRDILSRLIWGARITLYIVALVAMIAPIVGLLVGTVSGYVGGWVDIMLMRVTDIFLAFPRLVLALAFVAA
LGAGIENAVLAISLTAWPPYARLARAETLTIRSSDFISAIRLQGAGPLLIITKHIWPLCISSLIVRVTLDMAGIILAAAG
LGFLGLGAQPPSPEWGAMISEGRRFILDYWWVATMPGLAIFAVSLAFNLLGDGLRDVLDPKDSSS
>Mature_304_residues
SSQTMTLREWLLTDTPTSRRQARLAAYYKGWLTLRSNHMAMGGLAIIVLLVAVAIFAPLLAPHDPYYQDLGNRLQPLGTE
GHILGTDSLGRDILSRLIWGARITLYIVALVAMIAPIVGLLVGTVSGYVGGWVDIMLMRVTDIFLAFPRLVLALAFVAAL
GAGIENAVLAISLTAWPPYARLARAETLTIRSSDFISAIRLQGAGPLLIITKHIWPLCISSLIVRVTLDMAGIILAAAGL
GFLGLGAQPPSPEWGAMISEGRRFILDYWWVATMPGLAIFAVSLAFNLLGDGLRDVLDPKDSSS

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=294, Percent_Identity=43.1972789115646, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1787760, Length=288, Percent_Identity=42.3611111111111, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1789964, Length=275, Percent_Identity=46.9090909090909, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=42.3868312757202, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787498, Length=268, Percent_Identity=35.8208955223881, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787549, Length=269, Percent_Identity=37.1747211895911, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1788505, Length=227, Percent_Identity=26.431718061674, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32889; Mature: 32758

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQTMTLREWLLTDTPTSRRQARLAAYYKGWLTLRSNHMAMGGLAIIVLLVAVAIFAPL
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHH
LAPHDPYYQDLGNRLQPLGTEGHILGTDSLGRDILSRLIWGARITLYIVALVAMIAPIVG
HCCCCCHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVGTVSGYVGGWVDIMLMRVTDIFLAFPRLVLALAFVAALGAGIENAVLAISLTAWPPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCH
ARLARAETLTIRSSDFISAIRLQGAGPLLIITKHIWPLCISSLIVRVTLDMAGIILAAAG
HHHHHHHEEEEECHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFLGLGAQPPSPEWGAMISEGRRFILDYWWVATMPGLAIFAVSLAFNLLGDGLRDVLDP
HHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
KDSSS
CCCCC
>Mature Secondary Structure 
SSQTMTLREWLLTDTPTSRRQARLAAYYKGWLTLRSNHMAMGGLAIIVLLVAVAIFAPL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHH
LAPHDPYYQDLGNRLQPLGTEGHILGTDSLGRDILSRLIWGARITLYIVALVAMIAPIVG
HCCCCCHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVGTVSGYVGGWVDIMLMRVTDIFLAFPRLVLALAFVAALGAGIENAVLAISLTAWPPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCH
ARLARAETLTIRSSDFISAIRLQGAGPLLIITKHIWPLCISSLIVRVTLDMAGIILAAAG
HHHHHHHEEEEECHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFLGLGAQPPSPEWGAMISEGRRFILDYWWVATMPGLAIFAVSLAFNLLGDGLRDVLDP
HHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
KDSSS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]