Click here to switch to the map view.

The map label for this gene is hsdM [C]

Identifier: 94986116

GI number: 94986116

Start: 2127419

End: 2128972

Strand: Reverse

Name: hsdM [C]

Synonym: Dgeo_2017

Alternate gene names: 94986116

Gene position: 2128972-2127419 (Counterclockwise)

Preceding gene: 94986117

Following gene: 94986115

Centisome position: 86.29

GC content: 65.12

Gene sequence:

>1554_bases
ATGAAAAAGAATGGCACCACCAACAGCAACGGGGGCAACCTCGGCTTCGAGGCTGACCTTTTCAAGGCCGCTGACAAGCT
GCGCGGCAACATGGAGCCCAGCGACTACAAGCACGTCGCTCTGGGCTTGATCTTCCTCAAATACATCTCGGACGCCTTCG
AGGCCAGGCACCAGGCGCTGCTGGCCGAAGACCCGCGCGCGGCCGAAGACCGCGACGAGTACCTGGCCGACAACGTCTTC
TGGGTGCCGAAAGAGGCGCGCTGGTCGCACTTGCGGGCCAACGCCAGGCGGCCCGAGATCGGCCTCCTGATCGATGAGGC
CATGCGCGCCATCGAGAAGGAGAACGAGTCGCTCAAGGGCGTGTTGCCCAAGGACTACGCCAGGCCCGCGCTCAACAAGG
TGATGCTGGGCGAGTTGATCGACCTGATCTCCGGCATTGCGCTGGGCGAGGAAGGCGACCGCTCCAAGGACATCCTCGGG
CGCGTGTACGAATACTTCCTGGGCCAGTTCGCCGGCGCCGAGGGCAAGCGGGGCGGCGAGTTCTACACCCCGCGCTCGGT
GGTTCGCGTGCTGGTGGAGATGCTGGAGCCTTACCACGGGCGGGTGTATGACCCCTGCTGCGGCTCGGGCGGCATGTTCG
TGCAGAGCGAAAAGTTCGTGCAGGAGCACGGCGGGCGCATCGGTGACATCGCCATCTACGGGCAGGAGAGCAACTACACC
ACCTGGCGGCTGTGCAAGATGAACCTGGCGGTGCGCGGCATCGATGCCGACATCCGCTGGAACAACGAAGGCAGCTTCCA
CAAGGACGAACTGCGCGACCTCAAGGCCGATTTCATCCTCGCCAACCCGCCGTTCAACATCTCCGACTGGGGCGGCGAGC
GCCTGCGCGAGGACGTGCGCTGGAGTTTTGGCGTGCCGCCCGTGGGCAATGCCAACTACGCCTGGCTGCAGCACATCCAT
CACCACCTCGCCCCCAATGGCACCGCGGGTGTGGTCCTGGCCAACGGCTCGATGAGTTCGAACCAGTCGGGCGAGGGCGA
GATTCGCAAGGCCATGGTCGAGGCCGACGTGGTGGACTGCATGGTGGCGTTGCCCGGGCAGCTTTTCTACTCCACGCAGA
TTCCCGCCTGCCTGTGGTTCCTGGCACGCAACAAAAACCCCGGCAAGGGCCTGCGCGACCGCCGCGGACAGGTGCTGTTC
ATCGACGCGCGCAAGCTGGGCGTGCTGGTGGACCGCACCCGGCGCGAACTCACGGACGCCGAAATCCAGAAGATCGCCGA
CACCTACCACGCCTGGCGCGGTGAACCCGATGCGGGCGAATACCAGGACGTACCCGGCTTCTGCAAATCCGCCACGCTGG
AGGAGATCCGTAAACACGGCTTTGTCCTCACCCCGGGCCGCTATGTGGGCGCGGCACAGCAAGAGGACGACGGCGAGCCG
TTCGAGGAAAAAATGGCGCGGTTGGCGGCCCAGTGGCGCGAGCAGCGGGCAGCGGCGGCCAAGCTGGATGCGGCGATTGA
AGCCAACCTGAAGGAGCTTGGGTATGGCGGGTGA

Upstream 100 bases:

>100_bases
CAAGTGCGGCCTTGGGATGAAGCCGAAACCGCTAAGCTCGTGCTGGGGACCTTCTGCCCCCCCGAGAATCAAAAAAGCTG
ATGATGCAAAGGATGATGCG

Downstream 100 bases:

>100_bases
GTGGATAGATACAACGGTTGGCGAAATTGCCCCGTTTTCATATGGCAAGGGTTTGCCGGAACGTGAACGAAAGCAGACCG
GATCGGTGCCTGTTTATGGC

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKKNGTTNSNGGNLGFEADLFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHQALLAEDPRAAEDRDEYLADNVF
WVPKEARWSHLRANARRPEIGLLIDEAMRAIEKENESLKGVLPKDYARPALNKVMLGELIDLISGIALGEEGDRSKDILG
RVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVEMLEPYHGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNYT
TWRLCKMNLAVRGIDADIRWNNEGSFHKDELRDLKADFILANPPFNISDWGGERLREDVRWSFGVPPVGNANYAWLQHIH
HHLAPNGTAGVVLANGSMSSNQSGEGEIRKAMVEADVVDCMVALPGQLFYSTQIPACLWFLARNKNPGKGLRDRRGQVLF
IDARKLGVLVDRTRRELTDAEIQKIADTYHAWRGEPDAGEYQDVPGFCKSATLEEIRKHGFVLTPGRYVGAAQQEDDGEP
FEEKMARLAAQWREQRAAAAKLDAAIEANLKELGYGG

Sequences:

>Translated_517_residues
MKKNGTTNSNGGNLGFEADLFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHQALLAEDPRAAEDRDEYLADNVF
WVPKEARWSHLRANARRPEIGLLIDEAMRAIEKENESLKGVLPKDYARPALNKVMLGELIDLISGIALGEEGDRSKDILG
RVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVEMLEPYHGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNYT
TWRLCKMNLAVRGIDADIRWNNEGSFHKDELRDLKADFILANPPFNISDWGGERLREDVRWSFGVPPVGNANYAWLQHIH
HHLAPNGTAGVVLANGSMSSNQSGEGEIRKAMVEADVVDCMVALPGQLFYSTQIPACLWFLARNKNPGKGLRDRRGQVLF
IDARKLGVLVDRTRRELTDAEIQKIADTYHAWRGEPDAGEYQDVPGFCKSATLEEIRKHGFVLTPGRYVGAAQQEDDGEP
FEEKMARLAAQWREQRAAAAKLDAAIEANLKELGYGG
>Mature_517_residues
MKKNGTTNSNGGNLGFEADLFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHQALLAEDPRAAEDRDEYLADNVF
WVPKEARWSHLRANARRPEIGLLIDEAMRAIEKENESLKGVLPKDYARPALNKVMLGELIDLISGIALGEEGDRSKDILG
RVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVEMLEPYHGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNYT
TWRLCKMNLAVRGIDADIRWNNEGSFHKDELRDLKADFILANPPFNISDWGGERLREDVRWSFGVPPVGNANYAWLQHIH
HHLAPNGTAGVVLANGSMSSNQSGEGEIRKAMVEADVVDCMVALPGQLFYSTQIPACLWFLARNKNPGKGLRDRRGQVLF
IDARKLGVLVDRTRRELTDAEIQKIADTYHAWRGEPDAGEYQDVPGFCKSATLEEIRKHGFVLTPGRYVGAAQQEDDGEP
FEEKMARLAAQWREQRAAAAKLDAAIEANLKELGYGG

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=262, Percent_Identity=24.8091603053435, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57706; Mature: 57706

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNGTTNSNGGNLGFEADLFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHQAL
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEDPRAAEDRDEYLADNVFWVPKEARWSHLRANARRPEIGLLIDEAMRAIEKENESLKG
HCCCCCCCCCHHHHHHCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHCC
VLPKDYARPALNKVMLGELIDLISGIALGEEGDRSKDILGRVYEYFLGQFAGAEGKRGGE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
FYTPRSVVRVLVEMLEPYHGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNYT
CCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEECHHHHHHHHCCCEEEEEEEECCCCCC
TWRLCKMNLAVRGIDADIRWNNEGSFHKDELRDLKADFILANPPFNISDWGGERLREDVR
EEEEEEEEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
WSFGVPPVGNANYAWLQHIHHHLAPNGTAGVVLANGSMSSNQSGEGEIRKAMVEADVVDC
HCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
MVALPGQLFYSTQIPACLWFLARNKNPGKGLRDRRGQVLFIDARKLGVLVDRTRRELTDA
HHHCCCHHEECCCHHHHHHHHHCCCCCCCCHHHCCCCEEEEECHHHHHHHHHHHHHHHHH
EIQKIADTYHAWRGEPDAGEYQDVPGFCKSATLEEIRKHGFVLTPGRYVGAAQQEDDGEP
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCHHCCCCCCCCCCCC
FEEKMARLAAQWREQRAAAAKLDAAIEANLKELGYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKNGTTNSNGGNLGFEADLFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHQAL
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEDPRAAEDRDEYLADNVFWVPKEARWSHLRANARRPEIGLLIDEAMRAIEKENESLKG
HCCCCCCCCCHHHHHHCCCEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHCC
VLPKDYARPALNKVMLGELIDLISGIALGEEGDRSKDILGRVYEYFLGQFAGAEGKRGGE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
FYTPRSVVRVLVEMLEPYHGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNYT
CCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEECHHHHHHHHCCCEEEEEEEECCCCCC
TWRLCKMNLAVRGIDADIRWNNEGSFHKDELRDLKADFILANPPFNISDWGGERLREDVR
EEEEEEEEEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHH
WSFGVPPVGNANYAWLQHIHHHLAPNGTAGVVLANGSMSSNQSGEGEIRKAMVEADVVDC
HCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
MVALPGQLFYSTQIPACLWFLARNKNPGKGLRDRRGQVLFIDARKLGVLVDRTRRELTDA
HHHCCCHHEECCCHHHHHHHHHCCCCCCCCHHHCCCCEEEEECHHHHHHHHHHHHHHHHH
EIQKIADTYHAWRGEPDAGEYQDVPGFCKSATLEEIRKHGFVLTPGRYVGAAQQEDDGEP
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCHHCCCCCCCCCCCC
FEEKMARLAAQWREQRAAAAKLDAAIEANLKELGYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]