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The map label for this gene is cutS [H]

Identifier: 94986047

GI number: 94986047

Start: 2051258

End: 2051755

Strand: Reverse

Name: cutS [H]

Synonym: Dgeo_1948

Alternate gene names: 94986047

Gene position: 2051755-2051258 (Counterclockwise)

Preceding gene: 94986051

Following gene: 94986046

Centisome position: 83.16

GC content: 64.86

Gene sequence:

>498_bases
ATGAACGTGACCGTAACGGTAAATGGCCGCCCCTACACGCGTGACGTTGAACCGCGGACGCTGCTGGTGTACTTCCTGCG
CGAACATCTGGGCCTCACGGGCACCCACGTGGGCTGCGACACCAGCCAATGCGGCGCGTGTACCGTCCACCTGAACGGCC
ACGCGGTCAAGAGCTGCACCGTCCTGGCTGTGCAGGCTGATGGCCAGCAGGTCACCACCATCGAGGGCCTCGGTACCCCA
GCCGATCTCCACCCCCTTCAGGCAGGCTTCTGGGAGAAACATGGCCTCCAGTGCGGCTTTTGCACCCCCGGCATGATTAT
GAGCGCCGCCGAGCTGCTGAAGCACAACCCCGACCCCAGCGAGGAAGAGATTCGCCACCACCTCGAAGGCAACTACTGCC
GCTGCACCGGCTACCACAACATCGTCCTTGCTGTGCAGCAGGCGGCAAGCGCGATTCGCGAGGCAACGGCGGCAGCGGGA
CAGGCGGCGGACGACTGA

Upstream 100 bases:

>100_bases
AGACCCGTTCTCGGCTCGACACTCCCCTCTCGCCCCCAACTCGGAGGTGGACCATGCAGGACAGGAACCGCCGTACCCCG
CCCATTCGTGGAGGTCAACT

Downstream 100 bases:

>100_bases
GCTCAGCGCGGGAGGGACACCCCATGACCGAATCCAGACCCGAAAAATACGTAGGCCAGGCCCTCAAGCGCAAGGAAGAT
CCCCGCTTCATCACAGGGAC

Product: (2Fe-2S)-binding

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNVTVTVNGRPYTRDVEPRTLLVYFLREHLGLTGTHVGCDTSQCGACTVHLNGHAVKSCTVLAVQADGQQVTTIEGLGTP
ADLHPLQAGFWEKHGLQCGFCTPGMIMSAAELLKHNPDPSEEEIRHHLEGNYCRCTGYHNIVLAVQQAASAIREATAAAG
QAADD

Sequences:

>Translated_165_residues
MNVTVTVNGRPYTRDVEPRTLLVYFLREHLGLTGTHVGCDTSQCGACTVHLNGHAVKSCTVLAVQADGQQVTTIEGLGTP
ADLHPLQAGFWEKHGLQCGFCTPGMIMSAAELLKHNPDPSEEEIRHHLEGNYCRCTGYHNIVLAVQQAASAIREATAAAG
QAADD
>Mature_165_residues
MNVTVTVNGRPYTRDVEPRTLLVYFLREHLGLTGTHVGCDTSQCGACTVHLNGHAVKSCTVLAVQADGQQVTTIEGLGTP
ADLHPLQAGFWEKHGLQCGFCTPGMIMSAAELLKHNPDPSEEEIRHHLEGNYCRCTGYHNIVLAVQQAASAIREATAAAG
QAADD

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=148, Percent_Identity=42.5675675675676, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI71773480, Length=152, Percent_Identity=39.4736842105263, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=44.047619047619, Blast_Score=145, Evalue=1e-36,
Organism=Escherichia coli, GI1789232, Length=144, Percent_Identity=41.6666666666667, Blast_Score=111, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=43.5064935064935, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=150, Percent_Identity=40, Blast_Score=122, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=155, Percent_Identity=38.7096774193548, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17737937, Length=148, Percent_Identity=41.8918918918919, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=36.7088607594937, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=36.5853658536585, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=36.5853658536585, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24647199, Length=158, Percent_Identity=35.4430379746835, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=36.25, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17677; Mature: 17677

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTVTVNGRPYTRDVEPRTLLVYFLREHLGLTGTHVGCDTSQCGACTVHLNGHAVKSCT
CEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEECEEE
VLAVQADGQQVTTIEGLGTPADLHPLQAGFWEKHGLQCGFCTPGMIMSAAELLKHNPDPS
EEEEECCCCEEEEEECCCCCCCCCCCCCCCHHHCCCEECCCCCHHHHHHHHHHHCCCCCC
EEEIRHHLEGNYCRCTGYHNIVLAVQQAASAIREATAAAGQAADD
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNVTVTVNGRPYTRDVEPRTLLVYFLREHLGLTGTHVGCDTSQCGACTVHLNGHAVKSCT
CEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEECEEE
VLAVQADGQQVTTIEGLGTPADLHPLQAGFWEKHGLQCGFCTPGMIMSAAELLKHNPDPS
EEEEECCCCEEEEEECCCCCCCCCCCCCCCHHHCCCEECCCCCHHHHHHHHHHHCCCCCC
EEEIRHHLEGNYCRCTGYHNIVLAVQQAASAIREATAAAGQAADD
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]