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The map label for this gene is cutL [H]

Identifier: 94986046

GI number: 94986046

Start: 2048844

End: 2051234

Strand: Reverse

Name: cutL [H]

Synonym: Dgeo_1947

Alternate gene names: 94986046

Gene position: 2051234-2048844 (Counterclockwise)

Preceding gene: 94986047

Following gene: 94986045

Centisome position: 83.14

GC content: 65.96

Gene sequence:

>2391_bases
ATGACCGAATCCAGACCCGAAAAATACGTAGGCCAGGCCCTCAAGCGCAAGGAAGATCCCCGCTTCATCACAGGGACCGG
CCACTACACCGACGACTTTGTGCTGCCGGGGATGCTGCATGCGGCGATGGTGCGCAGTCCCTACGCGCACGCCCGGATTA
CGAACATCGACACGAGCAGTGTGGACGGGATGCCCGGCGTGGTGGCCGTGCTGACTGGTGAGGACGTGCGGGCGGCGGGC
CTGGGCAGCATCCCGGTCGGCTGGCTGCTGCCTGATCTGAAGGTGCCCGCACACCCCGCCATCGCGCAGGGCGAGGTGAA
TCACGTCGGGGACATCGTGGCGGCGGTGATTGCGGAGACGCGGGCGCAGGCGGAGGATGCGGCGGCGCTGCTGGCGGTGG
ACTACGAACCGCTGCCCTCGGTGGCACTGGGAAGTGCCGCGCTGGAGCAGGGCGCCCCACAGGTCCATGAGGACGTGCCC
GGCAATGTCGCTTTCCGGTGGGAGATCGGAGATGAGGCTGCGCTGCAGGAGGCCTTTAACCGGGCGCACAAGACGGTGAA
AGTGAAGCTTCGCAACCACCGCCTGATCCCCAATGCGATCGAGCCGCGTGCCTCGCTGGCACAGTTCACCCCCGCAAGCG
GCGAGTACACGCTCTACACCACCTCGCAAAACCCGCACATCCACCGCCTGATCCTGGCGGCCTTTGTGATGGGCATTCCC
GAGCACAAGCTGCGGGTGATCAGCCCAGATGTGGGCGGCGGCTTCGGCTCCAAGATCTTCCAATATCAGGAAGAGGTGAT
CGTGCTGCTTGCCGCGCAGAAGCTCGGCAAACCGGTGAAGTGGGCCGCCCGGCGCAGCGAGAGTTTCGTCTCGGACATGC
AGGGCCGCGACCACGAGTCTGAGGCCGAACTGGCGGTCGACGAACAGGGCCGAATGCTGGGGCTGCGCGTGCACACCGTC
GCCAACCTGGGTGCCTACCTCACGCTCTTTGCGCCCGCTGTGCCTACGTACCTCTACGGCACCCTGATGAACGGCGTGTA
CAAGTTCCCGGCCATCCACGTGAAGGTGACGGGCGTGCTGACCAACACCGTTCCGGTGGACGCCTATCGCGGCGCGGGTC
GCCCGGAGGCCACCTACCTGATCGAGCGCGTCGTGGACGTGATGGCGCATGAACTCGGGCTGGACCCTGCCGAGTTCCGC
CGCCGCAACTTCATCGGGCCTGACGAGTTCCCCTACCAGACACCCGTCGCCCTGGTCTATGACAGCGGCAACTATGAACC
GGCGCTCGACAAGGCGCTGGAGATGATGAACTACGCGGGACTGCGTGAGGAGCAGGCACGGCGCCGGGGAACGAACAAGA
TCCTGGGCATTGGGGTGATCTCCTACCTCGAGGCGTGTGGGCTGGCTCCCTCCGCGCTCGTCGGGCAACTGGGCGCACAG
GCCGGGCAATGGGAAAGCTCGCTGGTGCGGGTGCATCCGACCGGCAAGGTGGAGCTGTACACCGGCTCGCATAGCCACGG
ACAGGGCCACGAGACGGCCTTCCCGCAGATCGCCGCGGACGAACTCCAGATTCCCATCGAGGACATTGAGCTGATTCACG
GCGACACGGGCCGGATGCCCTACGGCTGGGGCACCTACGGCAGCCGCTCGGCGGCGGTGGGGGGCAGCGCGCTGAAGATG
GCCCTGGGCAAAATCACCGCCAAGGCCAGAAAGATCGCCGCACACCTGCTCGAAGTCTCCGAGGAGGACATCGAACACAA
AGATGGCGTTTTCCGGGTGAAGGGGGCGCCCTCACAACAGAAGACCTTCTTCGACGTGGCGCTGATGGCGCACCTGGCCC
ACAACCTGCCCGAAGGGATGGAGCCGGGCCTGGAGGCGACGGCCTTCTACGATCCCAAGAACTTTGTGTACCCCTTCGGC
ACCCATATCGCGGTGGTCGAAATCGACACCGACACCGGCCAGGTCACGCTGAAGCACTACGGCTGTGTGGACGACTGCGG
TCCCCTGATCAATCCCCTGATCGCAGAAGGACAGGTCCACGGCGGCATCGCGCAGGGTGCCGGGCAGGCCCTCTGGGAGG
AAGCCGCCTACGACGAGGACGGCAACCTGCTCGCCGGGACCTTCATGGAGTATGCCGTGCCCCGCGCCGACGATCTGCCC
AGCTTCCAGATTGACCACACGGTCACCCCCAGTCCCCACAATCCCCTCGGCGTGAAGGGCATCGGTGAGGCGGGGACAAT
CGCCAGCACCGCCGCCGTCGCCAACGCCGTCATGGACGCTCTCTGGCACGAGTACGGCATCCAGCACCTCGACATGCCCT
ACACCAGCGAGAAGGTCTGGCGCGCCATCCGTGAGGCGCGCGGCGGCCTGGGGCAGGCGGCAGACGACTGA

Upstream 100 bases:

>100_bases
TCGTCCTTGCTGTGCAGCAGGCGGCAAGCGCGATTCGCGAGGCAACGGCGGCAGCGGGACAGGCGGCGGACGACTGAGCT
CAGCGCGGGAGGGACACCCC

Downstream 100 bases:

>100_bases
GAGATCCCGGAGGAAACATGTACCCAGCCCAGTTCGACTATCAGAAAGCCGCCACTGTCGATGAGGCCCTGGCCTTGATG
GCGGCCAATCCGGACCTCAA

Product: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MTESRPEKYVGQALKRKEDPRFITGTGHYTDDFVLPGMLHAAMVRSPYAHARITNIDTSSVDGMPGVVAVLTGEDVRAAG
LGSIPVGWLLPDLKVPAHPAIAQGEVNHVGDIVAAVIAETRAQAEDAAALLAVDYEPLPSVALGSAALEQGAPQVHEDVP
GNVAFRWEIGDEAALQEAFNRAHKTVKVKLRNHRLIPNAIEPRASLAQFTPASGEYTLYTTSQNPHIHRLILAAFVMGIP
EHKLRVISPDVGGGFGSKIFQYQEEVIVLLAAQKLGKPVKWAARRSESFVSDMQGRDHESEAELAVDEQGRMLGLRVHTV
ANLGAYLTLFAPAVPTYLYGTLMNGVYKFPAIHVKVTGVLTNTVPVDAYRGAGRPEATYLIERVVDVMAHELGLDPAEFR
RRNFIGPDEFPYQTPVALVYDSGNYEPALDKALEMMNYAGLREEQARRRGTNKILGIGVISYLEACGLAPSALVGQLGAQ
AGQWESSLVRVHPTGKVELYTGSHSHGQGHETAFPQIAADELQIPIEDIELIHGDTGRMPYGWGTYGSRSAAVGGSALKM
ALGKITAKARKIAAHLLEVSEEDIEHKDGVFRVKGAPSQQKTFFDVALMAHLAHNLPEGMEPGLEATAFYDPKNFVYPFG
THIAVVEIDTDTGQVTLKHYGCVDDCGPLINPLIAEGQVHGGIAQGAGQALWEEAAYDEDGNLLAGTFMEYAVPRADDLP
SFQIDHTVTPSPHNPLGVKGIGEAGTIASTAAVANAVMDALWHEYGIQHLDMPYTSEKVWRAIREARGGLGQAADD

Sequences:

>Translated_796_residues
MTESRPEKYVGQALKRKEDPRFITGTGHYTDDFVLPGMLHAAMVRSPYAHARITNIDTSSVDGMPGVVAVLTGEDVRAAG
LGSIPVGWLLPDLKVPAHPAIAQGEVNHVGDIVAAVIAETRAQAEDAAALLAVDYEPLPSVALGSAALEQGAPQVHEDVP
GNVAFRWEIGDEAALQEAFNRAHKTVKVKLRNHRLIPNAIEPRASLAQFTPASGEYTLYTTSQNPHIHRLILAAFVMGIP
EHKLRVISPDVGGGFGSKIFQYQEEVIVLLAAQKLGKPVKWAARRSESFVSDMQGRDHESEAELAVDEQGRMLGLRVHTV
ANLGAYLTLFAPAVPTYLYGTLMNGVYKFPAIHVKVTGVLTNTVPVDAYRGAGRPEATYLIERVVDVMAHELGLDPAEFR
RRNFIGPDEFPYQTPVALVYDSGNYEPALDKALEMMNYAGLREEQARRRGTNKILGIGVISYLEACGLAPSALVGQLGAQ
AGQWESSLVRVHPTGKVELYTGSHSHGQGHETAFPQIAADELQIPIEDIELIHGDTGRMPYGWGTYGSRSAAVGGSALKM
ALGKITAKARKIAAHLLEVSEEDIEHKDGVFRVKGAPSQQKTFFDVALMAHLAHNLPEGMEPGLEATAFYDPKNFVYPFG
THIAVVEIDTDTGQVTLKHYGCVDDCGPLINPLIAEGQVHGGIAQGAGQALWEEAAYDEDGNLLAGTFMEYAVPRADDLP
SFQIDHTVTPSPHNPLGVKGIGEAGTIASTAAVANAVMDALWHEYGIQHLDMPYTSEKVWRAIREARGGLGQAADD
>Mature_795_residues
TESRPEKYVGQALKRKEDPRFITGTGHYTDDFVLPGMLHAAMVRSPYAHARITNIDTSSVDGMPGVVAVLTGEDVRAAGL
GSIPVGWLLPDLKVPAHPAIAQGEVNHVGDIVAAVIAETRAQAEDAAALLAVDYEPLPSVALGSAALEQGAPQVHEDVPG
NVAFRWEIGDEAALQEAFNRAHKTVKVKLRNHRLIPNAIEPRASLAQFTPASGEYTLYTTSQNPHIHRLILAAFVMGIPE
HKLRVISPDVGGGFGSKIFQYQEEVIVLLAAQKLGKPVKWAARRSESFVSDMQGRDHESEAELAVDEQGRMLGLRVHTVA
NLGAYLTLFAPAVPTYLYGTLMNGVYKFPAIHVKVTGVLTNTVPVDAYRGAGRPEATYLIERVVDVMAHELGLDPAEFRR
RNFIGPDEFPYQTPVALVYDSGNYEPALDKALEMMNYAGLREEQARRRGTNKILGIGVISYLEACGLAPSALVGQLGAQA
GQWESSLVRVHPTGKVELYTGSHSHGQGHETAFPQIAADELQIPIEDIELIHGDTGRMPYGWGTYGSRSAAVGGSALKMA
LGKITAKARKIAAHLLEVSEEDIEHKDGVFRVKGAPSQQKTFFDVALMAHLAHNLPEGMEPGLEATAFYDPKNFVYPFGT
HIAVVEIDTDTGQVTLKHYGCVDDCGPLINPLIAEGQVHGGIAQGAGQALWEEAAYDEDGNLLAGTFMEYAVPRADDLPS
FQIDHTVTPSPHNPLGVKGIGEAGTIASTAAVANAVMDALWHEYGIQHLDMPYTSEKVWRAIREARGGLGQAADD

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=811, Percent_Identity=25.5240443896424, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI91823271, Length=792, Percent_Identity=24.7474747474747, Blast_Score=147, Evalue=3e-35,
Organism=Escherichia coli, GI1789230, Length=767, Percent_Identity=28.0312907431552, Blast_Score=246, Evalue=4e-66,
Organism=Escherichia coli, GI1789246, Length=833, Percent_Identity=26.2905162064826, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1786478, Length=785, Percent_Identity=25.9872611464968, Blast_Score=131, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17540638, Length=764, Percent_Identity=24.3455497382199, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17539860, Length=790, Percent_Identity=24.5569620253165, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32566215, Length=793, Percent_Identity=23.203026481715, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17737937, Length=741, Percent_Identity=26.0458839406208, Blast_Score=146, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85844; Mature: 85713

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESRPEKYVGQALKRKEDPRFITGTGHYTDDFVLPGMLHAAMVRSPYAHARITNIDTSS
CCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
VDGMPGVVAVLTGEDVRAAGLGSIPVGWLLPDLKVPAHPAIAQGEVNHVGDIVAAVIAET
CCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RAQAEDAAALLAVDYEPLPSVALGSAALEQGAPQVHEDVPGNVAFRWEIGDEAALQEAFN
HHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCHHHHHHHHH
RAHKTVKVKLRNHRLIPNAIEPRASLAQFTPASGEYTLYTTSQNPHIHRLILAAFVMGIP
HHHHEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
EHKLRVISPDVGGGFGSKIFQYQEEVIVLLAAQKLGKPVKWAARRSESFVSDMQGRDHES
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
EAELAVDEQGRMLGLRVHTVANLGAYLTLFAPAVPTYLYGTLMNGVYKFPAIHVKVTGVL
CCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEE
TNTVPVDAYRGAGRPEATYLIERVVDVMAHELGLDPAEFRRRNFIGPDEFPYQTPVALVY
ECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEEEE
DSGNYEPALDKALEMMNYAGLREEQARRRGTNKILGIGVISYLEACGLAPSALVGQLGAQ
ECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHCCC
AGQWESSLVRVHPTGKVELYTGSHSHGQGHETAFPQIAADELQIPIEDIELIHGDTGRMP
CCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCHHHHHEEECCCCCCC
YGWGTYGSRSAAVGGSALKMALGKITAKARKIAAHLLEVSEEDIEHKDGVFRVKGAPSQQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
KTFFDVALMAHLAHNLPEGMEPGLEATAFYDPKNFVYPFGTHIAVVEIDTDTGQVTLKHY
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEECCCEEEEEEEECCCCEEEEEEC
GCVDDCGPLINPLIAEGQVHGGIAQGAGQALWEEAAYDEDGNLLAGTFMEYAVPRADDLP
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCC
SFQIDHTVTPSPHNPLGVKGIGEAGTIASTAAVANAVMDALWHEYGIQHLDMPYTSEKVW
CEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RAIREARGGLGQAADD
HHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TESRPEKYVGQALKRKEDPRFITGTGHYTDDFVLPGMLHAAMVRSPYAHARITNIDTSS
CCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
VDGMPGVVAVLTGEDVRAAGLGSIPVGWLLPDLKVPAHPAIAQGEVNHVGDIVAAVIAET
CCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RAQAEDAAALLAVDYEPLPSVALGSAALEQGAPQVHEDVPGNVAFRWEIGDEAALQEAFN
HHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCHHHHHHHHH
RAHKTVKVKLRNHRLIPNAIEPRASLAQFTPASGEYTLYTTSQNPHIHRLILAAFVMGIP
HHHHEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
EHKLRVISPDVGGGFGSKIFQYQEEVIVLLAAQKLGKPVKWAARRSESFVSDMQGRDHES
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
EAELAVDEQGRMLGLRVHTVANLGAYLTLFAPAVPTYLYGTLMNGVYKFPAIHVKVTGVL
CCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEE
TNTVPVDAYRGAGRPEATYLIERVVDVMAHELGLDPAEFRRRNFIGPDEFPYQTPVALVY
ECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEEEE
DSGNYEPALDKALEMMNYAGLREEQARRRGTNKILGIGVISYLEACGLAPSALVGQLGAQ
ECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHCCC
AGQWESSLVRVHPTGKVELYTGSHSHGQGHETAFPQIAADELQIPIEDIELIHGDTGRMP
CCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHCCCCHHHHHEEECCCCCCC
YGWGTYGSRSAAVGGSALKMALGKITAKARKIAAHLLEVSEEDIEHKDGVFRVKGAPSQQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
KTFFDVALMAHLAHNLPEGMEPGLEATAFYDPKNFVYPFGTHIAVVEIDTDTGQVTLKHY
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEECCCEEEEEEEECCCCEEEEEEC
GCVDDCGPLINPLIAEGQVHGGIAQGAGQALWEEAAYDEDGNLLAGTFMEYAVPRADDLP
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCCCCCC
SFQIDHTVTPSPHNPLGVKGIGEAGTIASTAAVANAVMDALWHEYGIQHLDMPYTSEKVW
CEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RAIREARGGLGQAADD
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]