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The map label for this gene is ycgM [C]

Identifier: 94985319

GI number: 94985319

Start: 1297494

End: 1298267

Strand: Reverse

Name: ycgM [C]

Synonym: Dgeo_1217

Alternate gene names: 94985319

Gene position: 1298267-1297494 (Counterclockwise)

Preceding gene: 94985322

Following gene: 94985318

Centisome position: 52.62

GC content: 66.8

Gene sequence:

>774_bases
GTGAGCGTATATCCTCCCTCCATGCGTCTTGTCAGGATGAACTGCGGCAACGCCCCCCGCTGGGGTCAGCTGGAGGGGAG
CACCATTCACCTCACGCGTGGCATGGGAGGCGAGCGGACGGGAGAGACGGTGCCGCTCGCAGGTGCCCAGCTGCTGGCGC
CTGCCGAACCCACCAAGATCGTCTGTGTGGGCCGCAACTACCTGGACCACATCCGGGAACTCGGCAACGACACGGGCGAC
CTGCCGGGTGAACCGGGCCTCTTTCTCAAGGGACCGAACGCGCTGGCCGAACCCGGCGGCACGGTGGCCTACCCCGACTG
GACGCAGAACTTTCACTACGAGGGCGAGTTGGCCCTGGTGATGGGGCAGCGGGCGCGCGACCTCAAGCCCGACACGGCCC
TCGCCGCGGTGCTGGGCTTTACCTGCGCCCTGGACCTGACGGCGCGTGACCTCCAGAAACAAGACCTCCAGTGGTTTCGC
GCCAAGGCTGCCGACCGCTTCTGCCCGCTGGGTCCCTGGCTGGAGACCGACTTCGACCCGACCGACGTACGTGTCCAAAC
GCGAGTGAACGGCGAGACCCGCCAGGACGGCCGCACCAGCCACATGATCTTCGATGTGGTGCAGATTCTGACCTATATCA
CTCGGTACGTGACGCTGGAACCCGGTGACGTGGTGCTCACCGGCACGCCTGAAGGGGTCGGCGCGCTGCAGCGGGGCGAC
ACGGTGGAGGTGGAGGTGGAGGGGATCGGCACGCTGGTGACGCCTATTGGCTAG

Upstream 100 bases:

>100_bases
GCCGCTCGTAGCGCTCGCGGTCATAGGGATCGCGCGTGTAGGTGAGGCCCGCCTGGGCAAGCAACTGAAGTTCACGAAGC
TGCGGGAGGGTCGGCATGGC

Downstream 100 bases:

>100_bases
CACATCTTGGTTGGCTAGCACACATGGGCCAGTGCCACGGTTCCTCCCCGCCCCGGCGCGCTAGCCTGAGGCGTGCCTCC
AGCCCGCCGCGTTTTGGCCC

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSVYPPSMRLVRMNCGNAPRWGQLEGSTIHLTRGMGGERTGETVPLAGAQLLAPAEPTKIVCVGRNYLDHIRELGNDTGD
LPGEPGLFLKGPNALAEPGGTVAYPDWTQNFHYEGELALVMGQRARDLKPDTALAAVLGFTCALDLTARDLQKQDLQWFR
AKAADRFCPLGPWLETDFDPTDVRVQTRVNGETRQDGRTSHMIFDVVQILTYITRYVTLEPGDVVLTGTPEGVGALQRGD
TVEVEVEGIGTLVTPIG

Sequences:

>Translated_257_residues
MSVYPPSMRLVRMNCGNAPRWGQLEGSTIHLTRGMGGERTGETVPLAGAQLLAPAEPTKIVCVGRNYLDHIRELGNDTGD
LPGEPGLFLKGPNALAEPGGTVAYPDWTQNFHYEGELALVMGQRARDLKPDTALAAVLGFTCALDLTARDLQKQDLQWFR
AKAADRFCPLGPWLETDFDPTDVRVQTRVNGETRQDGRTSHMIFDVVQILTYITRYVTLEPGDVVLTGTPEGVGALQRGD
TVEVEVEGIGTLVTPIG
>Mature_256_residues
SVYPPSMRLVRMNCGNAPRWGQLEGSTIHLTRGMGGERTGETVPLAGAQLLAPAEPTKIVCVGRNYLDHIRELGNDTGDL
PGEPGLFLKGPNALAEPGGTVAYPDWTQNFHYEGELALVMGQRARDLKPDTALAAVLGFTCALDLTARDLQKQDLQWFRA
KAADRFCPLGPWLETDFDPTDVRVQTRVNGETRQDGRTSHMIFDVVQILTYITRYVTLEPGDVVLTGTPEGVGALQRGDT
VEVEVEGIGTLVTPIG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=227, Percent_Identity=38.7665198237885, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=42.3469387755102, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI13654274, Length=199, Percent_Identity=41.7085427135678, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=42.3469387755102, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI40786394, Length=227, Percent_Identity=37.8854625550661, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1787428, Length=198, Percent_Identity=41.9191919191919, Blast_Score=147, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17557057, Length=204, Percent_Identity=44.1176470588235, Blast_Score=156, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6324161, Length=226, Percent_Identity=34.9557522123894, Blast_Score=123, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28572127, Length=219, Percent_Identity=36.986301369863, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24663695, Length=229, Percent_Identity=32.3144104803493, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571789, Length=200, Percent_Identity=32, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27944; Mature: 27813

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYPPSMRLVRMNCGNAPRWGQLEGSTIHLTRGMGGERTGETVPLAGAQLLAPAEPTKI
CCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCEE
VCVGRNYLDHIRELGNDTGDLPGEPGLFLKGPNALAEPGGTVAYPDWTQNFHYEGELALV
EEECCHHHHHHHHHCCCCCCCCCCCCEEEECCCHHCCCCCEEECCCCCCCCCCCCCEEEE
MGQRARDLKPDTALAAVLGFTCALDLTARDLQKQDLQWFRAKAADRFCPLGPWLETDFDP
ECCCCCCCCCHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TDVRVQTRVNGETRQDGRTSHMIFDVVQILTYITRYVTLEPGDVVLTGTPEGVGALQRGD
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHCCCC
TVEVEVEGIGTLVTPIG
EEEEEECCCEEEECCCC
>Mature Secondary Structure 
SVYPPSMRLVRMNCGNAPRWGQLEGSTIHLTRGMGGERTGETVPLAGAQLLAPAEPTKI
CCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCEE
VCVGRNYLDHIRELGNDTGDLPGEPGLFLKGPNALAEPGGTVAYPDWTQNFHYEGELALV
EEECCHHHHHHHHHCCCCCCCCCCCCEEEECCCHHCCCCCEEECCCCCCCCCCCCCEEEE
MGQRARDLKPDTALAAVLGFTCALDLTARDLQKQDLQWFRAKAADRFCPLGPWLETDFDP
ECCCCCCCCCHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
TDVRVQTRVNGETRQDGRTSHMIFDVVQILTYITRYVTLEPGDVVLTGTPEGVGALQRGD
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHCCCC
TVEVEVEGIGTLVTPIG
EEEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]