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The map label for this gene is prc [C]

Identifier: 94985318

GI number: 94985318

Start: 1296105

End: 1297421

Strand: Reverse

Name: prc [C]

Synonym: Dgeo_1216

Alternate gene names: 94985318

Gene position: 1297421-1296105 (Counterclockwise)

Preceding gene: 94985319

Following gene: 94985317

Centisome position: 52.59

GC content: 68.56

Gene sequence:

>1317_bases
GTGCCTCCAGCCCGCCGCGTTTTGGCCCTCGCGCTTCTCGTTGCCCTCCCGGCAGGGGCAAGCCCCGCGACGGATCTCTT
TGGCGCCGCCACCAGCGCCGTCGAGCACCAGTATTACGGGTGGTCCACTGTGGACCGCACACAACTAAGCCACAAATACG
CGGCGGTGCTCGCCGAAAAGTGCGCCCCGCAGGGGGACACCTGTGACTACGCGACCGCCCGAACCGTCTTGAACGACATG
CTGGGCGAGTTGGGCGATCCTCACACCAACCTGCGCGACGCCGAGGGAGCCGAGCGACTCGCCGAGATTGCCCAGAACCG
GGCCGTCAACCGCACAGGCGCGCGGGTGGTGCGGGTCACAGGCGGCCTGCTGGTTGTTTCGGTGATGCCCGGGAGTCCCG
CCGAACAGGTGGGGTTGCGCCGCCTTGACCTCCTCACCGAGGTGAACGGCCAGGCCGCCGGGAAAGATGATGCGGGAAAG
AACCTCCCGGTTGGCGCGAACGAGTTCATCCGGCTGGAACGGGAGGGGGCGCCCCTGCGCGTGACCCTGCGCCGCGCGGG
TCAGGCCGACCGTGAACTGACGCTGCCCACCGCCCGCCTCCAGGCCCGCGATGAACCAACCCTAAGCTGGACCGGGGCAG
ATGGCAAGACCGCCGTGATCGATTACCCTTCCTTTCTGCCGGGTGACAGTGCCGAGCTGTTCTTGAAGCGCGTGGGAGAG
GCGCAGGCACGCGGGGCCGGGGCGCTGGTGGTCGACCTGCGCTACAACGGTGGCGGGAGCCTGGACCAGTGTGTCGCGGC
GGCAAGCACTTTTGCTCCGGTTCTGTACAAGACCCGCTGGCGGGATGGCGGCTACACCTATGCGGGGCTGCGCGGCGAGG
TGACGTTCCCCTGGCTGGCTCGCCTGGCCCGTTCCGACTGGGGCCTCTGGCGCGGTCCACTGGCCGTGCTGGTGGGTCCA
AACACCGCCTCCTGCGCGGAGGTTTTTACCTACTATGCCCAGAAGGCCGGGGCCATCGTGGTGGGGGAGAAGACGCGCGG
GGTGGGCAACAGCGGCGTGATGTTCGAGCCGATGCCCGACGGCGGCGTGTTGTCGGTCACGGTTTTGCGGGCCTACACCG
ATGCGGGCGAGCCGCTTCCCGCGGCCATCACGCCGGATGTGGCCGCGCCTACCGATGTTGCCGTGCTGAGCAGCGAGGGC
CGCGACACCACGCTGGAGGCCGCCCTGGCCACTCTGAGCGCTCGCAGCGCGAATGGTGCAGGACAGACAGAGACCGGTCA
GGGGCAGGACGCTAACCTGAGTGCGGGCAGAAGGTAA

Upstream 100 bases:

>100_bases
CGGCACGCTGGTGACGCCTATTGGCTAGCACATCTTGGTTGGCTAGCACACATGGGCCAGTGCCACGGTTCCTCCCCGCC
CCGGCGCGCTAGCCTGAGGC

Downstream 100 bases:

>100_bases
CGCTCAACCGCGTACGACACGCGAACCGGCCCGTACACTAGAATCGATGCAGCACCTTCGCCCGCTTTTCAACACGCTGC
GCTCCGGCGCAACGTGGCCT

Product: peptidase S41

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MPPARRVLALALLVALPAGASPATDLFGAATSAVEHQYYGWSTVDRTQLSHKYAAVLAEKCAPQGDTCDYATARTVLNDM
LGELGDPHTNLRDAEGAERLAEIAQNRAVNRTGARVVRVTGGLLVVSVMPGSPAEQVGLRRLDLLTEVNGQAAGKDDAGK
NLPVGANEFIRLEREGAPLRVTLRRAGQADRELTLPTARLQARDEPTLSWTGADGKTAVIDYPSFLPGDSAELFLKRVGE
AQARGAGALVVDLRYNGGGSLDQCVAAASTFAPVLYKTRWRDGGYTYAGLRGEVTFPWLARLARSDWGLWRGPLAVLVGP
NTASCAEVFTYYAQKAGAIVVGEKTRGVGNSGVMFEPMPDGGVLSVTVLRAYTDAGEPLPAAITPDVAAPTDVAVLSSEG
RDTTLEAALATLSARSANGAGQTETGQGQDANLSAGRR

Sequences:

>Translated_438_residues
MPPARRVLALALLVALPAGASPATDLFGAATSAVEHQYYGWSTVDRTQLSHKYAAVLAEKCAPQGDTCDYATARTVLNDM
LGELGDPHTNLRDAEGAERLAEIAQNRAVNRTGARVVRVTGGLLVVSVMPGSPAEQVGLRRLDLLTEVNGQAAGKDDAGK
NLPVGANEFIRLEREGAPLRVTLRRAGQADRELTLPTARLQARDEPTLSWTGADGKTAVIDYPSFLPGDSAELFLKRVGE
AQARGAGALVVDLRYNGGGSLDQCVAAASTFAPVLYKTRWRDGGYTYAGLRGEVTFPWLARLARSDWGLWRGPLAVLVGP
NTASCAEVFTYYAQKAGAIVVGEKTRGVGNSGVMFEPMPDGGVLSVTVLRAYTDAGEPLPAAITPDVAAPTDVAVLSSEG
RDTTLEAALATLSARSANGAGQTETGQGQDANLSAGRR
>Mature_437_residues
PPARRVLALALLVALPAGASPATDLFGAATSAVEHQYYGWSTVDRTQLSHKYAAVLAEKCAPQGDTCDYATARTVLNDML
GELGDPHTNLRDAEGAERLAEIAQNRAVNRTGARVVRVTGGLLVVSVMPGSPAEQVGLRRLDLLTEVNGQAAGKDDAGKN
LPVGANEFIRLEREGAPLRVTLRRAGQADRELTLPTARLQARDEPTLSWTGADGKTAVIDYPSFLPGDSAELFLKRVGEA
QARGAGALVVDLRYNGGGSLDQCVAAASTFAPVLYKTRWRDGGYTYAGLRGEVTFPWLARLARSDWGLWRGPLAVLVGPN
TASCAEVFTYYAQKAGAIVVGEKTRGVGNSGVMFEPMPDGGVLSVTVLRAYTDAGEPLPAAITPDVAAPTDVAVLSSEGR
DTTLEAALATLSARSANGAGQTETGQGQDANLSAGRR

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 45956; Mature: 45825

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPARRVLALALLVALPAGASPATDLFGAATSAVEHQYYGWSTVDRTQLSHKYAAVLAEK
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
CAPQGDTCDYATARTVLNDMLGELGDPHTNLRDAEGAERLAEIAQNRAVNRTGARVVRVT
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
GGLLVVSVMPGSPAEQVGLRRLDLLTEVNGQAAGKDDAGKNLPVGANEFIRLEREGAPLR
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEEECCCCCEE
VTLRRAGQADRELTLPTARLQARDEPTLSWTGADGKTAVIDYPSFLPGDSAELFLKRVGE
EEEECCCCCCCEEECCHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHH
AQARGAGALVVDLRYNGGGSLDQCVAAASTFAPVLYKTRWRDGGYTYAGLRGEVTFPWLA
HHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHH
RLARSDWGLWRGPLAVLVGPNTASCAEVFTYYAQKAGAIVVGEKTRGVGNSGVMFEPMPD
HHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEECCC
GGVLSVTVLRAYTDAGEPLPAAITPDVAAPTDVAVLSSEGRDTTLEAALATLSARSANGA
CCEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC
GQTETGQGQDANLSAGRR
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPARRVLALALLVALPAGASPATDLFGAATSAVEHQYYGWSTVDRTQLSHKYAAVLAEK
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
CAPQGDTCDYATARTVLNDMLGELGDPHTNLRDAEGAERLAEIAQNRAVNRTGARVVRVT
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEE
GGLLVVSVMPGSPAEQVGLRRLDLLTEVNGQAAGKDDAGKNLPVGANEFIRLEREGAPLR
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEEECCCCCEE
VTLRRAGQADRELTLPTARLQARDEPTLSWTGADGKTAVIDYPSFLPGDSAELFLKRVGE
EEEECCCCCCCEEECCHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHH
AQARGAGALVVDLRYNGGGSLDQCVAAASTFAPVLYKTRWRDGGYTYAGLRGEVTFPWLA
HHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHH
RLARSDWGLWRGPLAVLVGPNTASCAEVFTYYAQKAGAIVVGEKTRGVGNSGVMFEPMPD
HHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEECCC
GGVLSVTVLRAYTDAGEPLPAAITPDVAAPTDVAVLSSEGRDTTLEAALATLSARSANGA
CCEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC
GQTETGQGQDANLSAGRR
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA