Click here to switch to the map view.

The map label for this gene is ileS [H]

Identifier: 94985204

GI number: 94985204

Start: 1169134

End: 1172409

Strand: Reverse

Name: ileS [H]

Synonym: Dgeo_1101

Alternate gene names: 94985204

Gene position: 1172409-1169134 (Counterclockwise)

Preceding gene: 94985213

Following gene: 94985202

Centisome position: 47.52

GC content: 66.91

Gene sequence:

>3276_bases
ATGACCACCAAGACCCAAGCTTCTCCCCTGTTTCAACCGGTGGGTTCGCAGCCCAGCTTCCGTGAGCTGGAGGCAGGCAT
CCTGAACTTCTGGCAGGAGAACCGCATCTTTGAGCAAACGCAGGAACGCCAAGACGGACAGCCTGAATTTGTGTTCTACG
AGGGGCCACCCACGGCCAACGGACGCCCGGCGCTGCACCACGTTCTGGCACGTTCCTTTAAAGACCTCTTTCCGCGCTAC
AAGGTGATGCAGGGCTACTTTGTGACCCGCAAGGGCGGCTGGGACACCCACGGCCTCCCGGTCGAGATCAGCGTGGAGAA
AAAACTCGGGCTGCTCGGACGCAACCACGGCGCGAGCCGCGAGGAGCTGGAGGAGTTCAACCGCCTGTGCCGCGCGTCGG
TCTGGGAAACGATTCAGGAGTGGAACACCTTTACCCAGCGCCTGGGCTACTGGGTGGACCTCAGTGATCCCTACATCACG
TATGAAAACGAATACGTGGAGAGCGTGTGGAACCTGCTCAAGAGGCTTCACGCCAAAGGGCTGATCGCACAGGACTACAA
GGTGGTGCCGCTCTCGCCGCGCATCAGCACCACCCTCTCGCGCGCGGAGCTGGGCGAGGTGGACTCTTACCGGATGGTGG
ATGATCCCAGCGTGTACGTGCGCTTCCCGGTGATCTGGGACACCCTGCCTGAGCGGGCGCGGGCCGCGTTGGCGACGCTG
GACGAGGCCGACCGCCAGGATCTCGCCCTGGTGGTGTGGACCACGACCCCCTGGACCCTCCCCAGCAACACGCTCGCGGC
GGTGAATCCGGACCTCACCTACGTGGTGGCACGCAGTGGGCTGGGGCCGGTGATCGTGGCGGCAGATGCTACCCGGCGCC
TCTCGGAGCTGCACAAGCACTGGGCGCCGCTGGAGGTGCTGACCAGCTTTCCAGGCCGCGACCTGGAGGGCGTGGAGTAC
GAGCCGCCCTTTCCAGAGGTCGCCACCGAGCTGGGCGTCTTGAGGGAGCTGCACGAGCGCAACGCCGAGGGCCGCCCGGT
GATGCACTTTGTCGCGCTGGCGGATTTTGTGTCGGCAGCGGACGGCTCCGGCGTGGCGCACGAGGCCCCCGCATACGGCG
CAGAGGACCTCGAACTGGCCCGCCGGTACGAGGTGCCGCTGCTGTTCGGGGTGGACGATCACGGCATTCTGCAGGTAACG
AAGGAGCGGGGCAAGTTCTTCAAGGACGCCGACAAGGGCCTGATCGCCGATCTCAAGGCGCGGGGGCTGATGTTCCACGC
GGGCACCATCCGGCACCGTTATCCCTTCCACGACCGCACAGGCGACCCCATCCTCTACTTCGCCAAGAAGGGCTGGTACA
TCCGCACCAACTCGGTGGCGGACCGCATGCTAGAGACGAACGAGGAGATCAACTGGGTGCCGCCGGGCATCAAGCACGGG
AGATTCGGCCACTGGCTGGAGGGCAACGTGGACTGGGCCATCTCCCGCGAGCGCTACTGGGGCACCCCGCTTCCCTTCTG
GATGAGCGAGGACGGCGACCTGCAGGTGGTGGGGAGCGTGGCAGAGCTCTCGGCGCTGACCGGACGCGACCTCACCGGAC
TGGACCTGCACCGGCCCTCTATCGATGACGTGACCTTTACGCGAGACGGCAAGACGTACCGCCGGGTGCCGGAGGTGCTG
GACGTGTGGTTTGACTCCGGCGCGATGCCCTACGCGCAGTGGCACCTGCTCACCGACGAGACGGGCGAGCACGCGCTGCC
GGGCACCGAAGCCAACCTGAGGCAGTTTGAGCGGCATTTCCCCGCCGACTTCATCAGCGAGGCAATCGACCAGACGCGCG
GCTGGTTCTACTCCCTGCACGCGATCGCCACCATGCTCTACGACCAGCCCGCCTACCGAAACGTGATCTGCCTGGGGCAC
ATCGTGGACGAGCACGGCGCCAAGATGAGCAAGAGCAAGGGCAACGTGGTGGAGCCGCTCCCGCTGTTTGACCGCTACGG
TGCGGACTCGGTGCGCTGGTACATGTTCATGGCGTCGGACCCCGGCGACCAGAAGCGCTTCTCCGAGCGGCTGGTGGCGG
AGGCGCAGCGCAATTACGTCAACACGCTGTGGAACGTGTATGCCTTTTTCGTGCTGTACGCGAACCTGGACCGCCCCGAG
CTGGGGGCCGCACCCGCCGTCGCTGAGCGCCCCGAGATGGACCGCTGGCTGCTCGCGCGCCTCGAGGAGACGGTGCGGGA
CGTGACGACCTCGCTCGACGCCTATGACGCCCGCGGCGGTGGACGGGCGCTGGAACGCTTTGTGCACGACCTCAGCAACT
GGTACGTCCGGCGCAACCGTTCCCGATTCTGGGGTGAAGGTGGGCAGGTGGACCTGAGCGCCTACGCCACGCTTCATGAG
GCCCTCCTGACGGTCTCGCAGCTCACCGCCCCCTTCACGCCGTTCCTGGCCGAGGCGCTGTACCGCAACCTCACGCGTGG
GGAGGGGGCCTTGAGCGTTCACCTCACCCGCTGGCCGCAGGTCCGCCCCGAGCGGCTCGACGAGCGGCTGACGGCGGAGA
TGGCCGCCGTGATGAAGGTGGTGGAGCTGGGCCGGGCGGTGCGCGGCGCGCACAACCTCAAGACGCGGCAACCACTCGCC
AGCGTCACGGTGCGGGCCAGCACGCCCGAGCTGACAGAAGCGCTGCGCCGGGCGCAGGAGCAGCTCAAAGAAGAGCTGAA
TGTCAAGCAGGTGATCTTCCTGGAGGGTGTGACGGATCTGGTGCGCTACAGCCTGCGCCCCAACCTGCCGGTCCTGGGCA
AGGTGTACGGCAAAGCGCTCCCCGCGGTGCGCGCGGCACTCGAGCAGGCGGACGCGGCGGCGGTGGCTCACGCTGTTCAG
CGCGGCGAGCGCTTCACGGTGGCGGCGAATGGACAGACGTTCACACTCACGCCGGAACAGGTGCTTGTGGACGCCAAGGC
GCCCGAAGGCGTCGCGGCGGCGGAAGACGGCGGCTTCTTGGTCGCCTTCGACACGCAGCTCACCCCTGAGCTGCTGCGAG
AAGGCTTGGCCCGAGACTTGGTGCGCGGCATCCAGGAGGCGCGCAAAGCGGCGGGCTTCGAGGTGCAAGACCGCATCCGC
CTCGCGCTGGACTTGACGGGCGACGCCCGTGAAGCCGCCGAGACGTGGCGTGACTTTATCGCGGGAGAGGTGCTGGCGAC
CGAGCTGACCTTCGGGCCGGGCGAGGGATACGCGGCGGCGGTGGAAGGCGGCACGGCCTACCTGCTGCGGCACTGA

Upstream 100 bases:

>100_bases
AAGTTGGGTGGTACCACGCGCACAGGCGTTTCCCGGCGCGTCCCAGCAGGCCATCTGGGACGCGCCGCTGTTTTTCCACT
GTTTTTCCATAAGGAGCCAT

Downstream 100 bases:

>100_bases
GGAAGCCTTAACCCACCTGTGGCCAGCAGCTCAGACCCGCCCCCGAGCATGGCGGTGAGGAGGAAGCATGCCCTACAAGA
GCATCGCGGATCTGCCCCAG

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1091; Mature: 1090

Protein sequence:

>1091_residues
MTTKTQASPLFQPVGSQPSFRELEAGILNFWQENRIFEQTQERQDGQPEFVFYEGPPTANGRPALHHVLARSFKDLFPRY
KVMQGYFVTRKGGWDTHGLPVEISVEKKLGLLGRNHGASREELEEFNRLCRASVWETIQEWNTFTQRLGYWVDLSDPYIT
YENEYVESVWNLLKRLHAKGLIAQDYKVVPLSPRISTTLSRAELGEVDSYRMVDDPSVYVRFPVIWDTLPERARAALATL
DEADRQDLALVVWTTTPWTLPSNTLAAVNPDLTYVVARSGLGPVIVAADATRRLSELHKHWAPLEVLTSFPGRDLEGVEY
EPPFPEVATELGVLRELHERNAEGRPVMHFVALADFVSAADGSGVAHEAPAYGAEDLELARRYEVPLLFGVDDHGILQVT
KERGKFFKDADKGLIADLKARGLMFHAGTIRHRYPFHDRTGDPILYFAKKGWYIRTNSVADRMLETNEEINWVPPGIKHG
RFGHWLEGNVDWAISRERYWGTPLPFWMSEDGDLQVVGSVAELSALTGRDLTGLDLHRPSIDDVTFTRDGKTYRRVPEVL
DVWFDSGAMPYAQWHLLTDETGEHALPGTEANLRQFERHFPADFISEAIDQTRGWFYSLHAIATMLYDQPAYRNVICLGH
IVDEHGAKMSKSKGNVVEPLPLFDRYGADSVRWYMFMASDPGDQKRFSERLVAEAQRNYVNTLWNVYAFFVLYANLDRPE
LGAAPAVAERPEMDRWLLARLEETVRDVTTSLDAYDARGGGRALERFVHDLSNWYVRRNRSRFWGEGGQVDLSAYATLHE
ALLTVSQLTAPFTPFLAEALYRNLTRGEGALSVHLTRWPQVRPERLDERLTAEMAAVMKVVELGRAVRGAHNLKTRQPLA
SVTVRASTPELTEALRRAQEQLKEELNVKQVIFLEGVTDLVRYSLRPNLPVLGKVYGKALPAVRAALEQADAAAVAHAVQ
RGERFTVAANGQTFTLTPEQVLVDAKAPEGVAAAEDGGFLVAFDTQLTPELLREGLARDLVRGIQEARKAAGFEVQDRIR
LALDLTGDAREAAETWRDFIAGEVLATELTFGPGEGYAAAVEGGTAYLLRH

Sequences:

>Translated_1091_residues
MTTKTQASPLFQPVGSQPSFRELEAGILNFWQENRIFEQTQERQDGQPEFVFYEGPPTANGRPALHHVLARSFKDLFPRY
KVMQGYFVTRKGGWDTHGLPVEISVEKKLGLLGRNHGASREELEEFNRLCRASVWETIQEWNTFTQRLGYWVDLSDPYIT
YENEYVESVWNLLKRLHAKGLIAQDYKVVPLSPRISTTLSRAELGEVDSYRMVDDPSVYVRFPVIWDTLPERARAALATL
DEADRQDLALVVWTTTPWTLPSNTLAAVNPDLTYVVARSGLGPVIVAADATRRLSELHKHWAPLEVLTSFPGRDLEGVEY
EPPFPEVATELGVLRELHERNAEGRPVMHFVALADFVSAADGSGVAHEAPAYGAEDLELARRYEVPLLFGVDDHGILQVT
KERGKFFKDADKGLIADLKARGLMFHAGTIRHRYPFHDRTGDPILYFAKKGWYIRTNSVADRMLETNEEINWVPPGIKHG
RFGHWLEGNVDWAISRERYWGTPLPFWMSEDGDLQVVGSVAELSALTGRDLTGLDLHRPSIDDVTFTRDGKTYRRVPEVL
DVWFDSGAMPYAQWHLLTDETGEHALPGTEANLRQFERHFPADFISEAIDQTRGWFYSLHAIATMLYDQPAYRNVICLGH
IVDEHGAKMSKSKGNVVEPLPLFDRYGADSVRWYMFMASDPGDQKRFSERLVAEAQRNYVNTLWNVYAFFVLYANLDRPE
LGAAPAVAERPEMDRWLLARLEETVRDVTTSLDAYDARGGGRALERFVHDLSNWYVRRNRSRFWGEGGQVDLSAYATLHE
ALLTVSQLTAPFTPFLAEALYRNLTRGEGALSVHLTRWPQVRPERLDERLTAEMAAVMKVVELGRAVRGAHNLKTRQPLA
SVTVRASTPELTEALRRAQEQLKEELNVKQVIFLEGVTDLVRYSLRPNLPVLGKVYGKALPAVRAALEQADAAAVAHAVQ
RGERFTVAANGQTFTLTPEQVLVDAKAPEGVAAAEDGGFLVAFDTQLTPELLREGLARDLVRGIQEARKAAGFEVQDRIR
LALDLTGDAREAAETWRDFIAGEVLATELTFGPGEGYAAAVEGGTAYLLRH
>Mature_1090_residues
TTKTQASPLFQPVGSQPSFRELEAGILNFWQENRIFEQTQERQDGQPEFVFYEGPPTANGRPALHHVLARSFKDLFPRYK
VMQGYFVTRKGGWDTHGLPVEISVEKKLGLLGRNHGASREELEEFNRLCRASVWETIQEWNTFTQRLGYWVDLSDPYITY
ENEYVESVWNLLKRLHAKGLIAQDYKVVPLSPRISTTLSRAELGEVDSYRMVDDPSVYVRFPVIWDTLPERARAALATLD
EADRQDLALVVWTTTPWTLPSNTLAAVNPDLTYVVARSGLGPVIVAADATRRLSELHKHWAPLEVLTSFPGRDLEGVEYE
PPFPEVATELGVLRELHERNAEGRPVMHFVALADFVSAADGSGVAHEAPAYGAEDLELARRYEVPLLFGVDDHGILQVTK
ERGKFFKDADKGLIADLKARGLMFHAGTIRHRYPFHDRTGDPILYFAKKGWYIRTNSVADRMLETNEEINWVPPGIKHGR
FGHWLEGNVDWAISRERYWGTPLPFWMSEDGDLQVVGSVAELSALTGRDLTGLDLHRPSIDDVTFTRDGKTYRRVPEVLD
VWFDSGAMPYAQWHLLTDETGEHALPGTEANLRQFERHFPADFISEAIDQTRGWFYSLHAIATMLYDQPAYRNVICLGHI
VDEHGAKMSKSKGNVVEPLPLFDRYGADSVRWYMFMASDPGDQKRFSERLVAEAQRNYVNTLWNVYAFFVLYANLDRPEL
GAAPAVAERPEMDRWLLARLEETVRDVTTSLDAYDARGGGRALERFVHDLSNWYVRRNRSRFWGEGGQVDLSAYATLHEA
LLTVSQLTAPFTPFLAEALYRNLTRGEGALSVHLTRWPQVRPERLDERLTAEMAAVMKVVELGRAVRGAHNLKTRQPLAS
VTVRASTPELTEALRRAQEQLKEELNVKQVIFLEGVTDLVRYSLRPNLPVLGKVYGKALPAVRAALEQADAAAVAHAVQR
GERFTVAANGQTFTLTPEQVLVDAKAPEGVAAAEDGGFLVAFDTQLTPELLREGLARDLVRGIQEARKAAGFEVQDRIRL
ALDLTGDAREAAETWRDFIAGEVLATELTFGPGEGYAAAVEGGTAYLLRH

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1069, Percent_Identity=35.4536950420954, Blast_Score=615, Evalue=1e-176,
Organism=Homo sapiens, GI94721241, Length=1069, Percent_Identity=35.4536950420954, Blast_Score=615, Evalue=1e-176,
Organism=Homo sapiens, GI46852147, Length=828, Percent_Identity=26.3285024154589, Blast_Score=255, Evalue=2e-67,
Organism=Homo sapiens, GI268370293, Length=942, Percent_Identity=22.6114649681529, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI268370297, Length=942, Percent_Identity=22.6114649681529, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI5454158, Length=932, Percent_Identity=21.244635193133, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI268370295, Length=902, Percent_Identity=22.6164079822616, Blast_Score=124, Evalue=7e-28,
Organism=Escherichia coli, GI2367096, Length=915, Percent_Identity=26.0109289617486, Blast_Score=245, Evalue=1e-65,
Organism=Escherichia coli, GI1790708, Length=953, Percent_Identity=23.189926547744, Blast_Score=151, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17541896, Length=1052, Percent_Identity=34.9809885931559, Blast_Score=559, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71980946, Length=925, Percent_Identity=24.6486486486486, Blast_Score=207, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1063, Percent_Identity=33.6782690498589, Blast_Score=563, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6325217, Length=868, Percent_Identity=23.7327188940092, Blast_Score=213, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6321531, Length=918, Percent_Identity=21.8954248366013, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574730, Length=1078, Percent_Identity=32.6530612244898, Blast_Score=540, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24668547, Length=1078, Percent_Identity=32.6530612244898, Blast_Score=540, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24668543, Length=1078, Percent_Identity=32.6530612244898, Blast_Score=540, Evalue=1e-153,
Organism=Drosophila melanogaster, GI281366294, Length=860, Percent_Identity=26.3953488372093, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI17864482, Length=969, Percent_Identity=22.3942208462332, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24653289, Length=969, Percent_Identity=22.3942208462332, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21355675, Length=917, Percent_Identity=20.2835332606325, Blast_Score=110, Evalue=6e-24,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 122775; Mature: 122644

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKTQASPLFQPVGSQPSFRELEAGILNFWQENRIFEQTQERQDGQPEFVFYEGPPTAN
CCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEECCCCCCC
GRPALHHVLARSFKDLFPRYKVMQGYFVTRKGGWDTHGLPVEISVEKKLGLLGRNHGASR
CCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCCCCH
EELEEFNRLCRASVWETIQEWNTFTQRLGYWVDLSDPYITYENEYVESVWNLLKRLHAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECHHHHHHHHHHHHHHHHCC
LIAQDYKVVPLSPRISTTLSRAELGEVDSYRMVDDPSVYVRFPVIWDTLPERARAALATL
EEECCCEEEECCCCHHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHH
DEADRQDLALVVWTTTPWTLPSNTLAAVNPDLTYVVARSGLGPVIVAADATRRLSELHKH
HHCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCEEEECCHHHHHHHHHHC
WAPLEVLTSFPGRDLEGVEYEPPFPEVATELGVLRELHERNAEGRPVMHFVALADFVSAA
CCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DGSGVAHEAPAYGAEDLELARRYEVPLLFGVDDHGILQVTKERGKFFKDADKGLIADLKA
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEEEHHHCCHHHHCCCCHHHHHHH
RGLMFHAGTIRHRYPFHDRTGDPILYFAKKGWYIRTNSVADRMLETNEEINWVPPGIKHG
CCEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEECHHHHHHHHCCCCCCCCCCCCCCC
RFGHWLEGNVDWAISRERYWGTPLPFWMSEDGDLQVVGSVAELSALTGRDLTGLDLHRPS
CCCCEECCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCCCCC
IDDVTFTRDGKTYRRVPEVLDVWFDSGAMPYAQWHLLTDETGEHALPGTEANLRQFERHF
CCCEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHC
PADFISEAIDQTRGWFYSLHAIATMLYDQPAYRNVICLGHIVDEHGAKMSKSKGNVVEPL
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCC
PLFDRYGADSVRWYMFMASDPGDQKRFSERLVAEAQRNYVNTLWNVYAFFVLYANLDRPE
CHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LGAAPAVAERPEMDRWLLARLEETVRDVTTSLDAYDARGGGRALERFVHDLSNWYVRRNR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
SRFWGEGGQVDLSAYATLHEALLTVSQLTAPFTPFLAEALYRNLTRGEGALSVHLTRWPQ
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
VRPERLDERLTAEMAAVMKVVELGRAVRGAHNLKTRQPLASVTVRASTPELTEALRRAQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCHHHHHHHHHHHH
QLKEELNVKQVIFLEGVTDLVRYSLRPNLPVLGKVYGKALPAVRAALEQADAAAVAHAVQ
HHHHHCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGERFTVAANGQTFTLTPEQVLVDAKAPEGVAAAEDGGFLVAFDTQLTPELLREGLARDL
CCCEEEEEECCCEEEECHHHHEEECCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHH
VRGIQEARKAAGFEVQDRIRLALDLTGDAREAAETWRDFIAGEVLATELTFGPGEGYAAA
HHHHHHHHHHCCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEE
VEGGTAYLLRH
ECCCEEEEEEC
>Mature Secondary Structure 
TTKTQASPLFQPVGSQPSFRELEAGILNFWQENRIFEQTQERQDGQPEFVFYEGPPTAN
CCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEECCCCCCC
GRPALHHVLARSFKDLFPRYKVMQGYFVTRKGGWDTHGLPVEISVEKKLGLLGRNHGASR
CCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEEHHHHHHHCCCCCCCH
EELEEFNRLCRASVWETIQEWNTFTQRLGYWVDLSDPYITYENEYVESVWNLLKRLHAKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECHHHHHHHHHHHHHHHHCC
LIAQDYKVVPLSPRISTTLSRAELGEVDSYRMVDDPSVYVRFPVIWDTLPERARAALATL
EEECCCEEEECCCCHHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHH
DEADRQDLALVVWTTTPWTLPSNTLAAVNPDLTYVVARSGLGPVIVAADATRRLSELHKH
HHCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCEEEECCHHHHHHHHHHC
WAPLEVLTSFPGRDLEGVEYEPPFPEVATELGVLRELHERNAEGRPVMHFVALADFVSAA
CCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DGSGVAHEAPAYGAEDLELARRYEVPLLFGVDDHGILQVTKERGKFFKDADKGLIADLKA
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEEEHHHCCHHHHCCCCHHHHHHH
RGLMFHAGTIRHRYPFHDRTGDPILYFAKKGWYIRTNSVADRMLETNEEINWVPPGIKHG
CCEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEEECHHHHHHHHCCCCCCCCCCCCCCC
RFGHWLEGNVDWAISRERYWGTPLPFWMSEDGDLQVVGSVAELSALTGRDLTGLDLHRPS
CCCCEECCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCCCCC
IDDVTFTRDGKTYRRVPEVLDVWFDSGAMPYAQWHLLTDETGEHALPGTEANLRQFERHF
CCCEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHC
PADFISEAIDQTRGWFYSLHAIATMLYDQPAYRNVICLGHIVDEHGAKMSKSKGNVVEPL
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCC
PLFDRYGADSVRWYMFMASDPGDQKRFSERLVAEAQRNYVNTLWNVYAFFVLYANLDRPE
CHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LGAAPAVAERPEMDRWLLARLEETVRDVTTSLDAYDARGGGRALERFVHDLSNWYVRRNR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
SRFWGEGGQVDLSAYATLHEALLTVSQLTAPFTPFLAEALYRNLTRGEGALSVHLTRWPQ
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
VRPERLDERLTAEMAAVMKVVELGRAVRGAHNLKTRQPLASVTVRASTPELTEALRRAQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCHHHHHHHHHHHH
QLKEELNVKQVIFLEGVTDLVRYSLRPNLPVLGKVYGKALPAVRAALEQADAAAVAHAVQ
HHHHHCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGERFTVAANGQTFTLTPEQVLVDAKAPEGVAAAEDGGFLVAFDTQLTPELLREGLARDL
CCCEEEEEECCCEEEECHHHHEEECCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHH
VRGIQEARKAAGFEVQDRIRLALDLTGDAREAAETWRDFIAGEVLATELTFGPGEGYAAA
HHHHHHHHHHCCCCHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEE
VEGGTAYLLRH
ECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]