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The map label for this gene is setA [C]

Identifier: 94985132

GI number: 94985132

Start: 1098468

End: 1098950

Strand: Reverse

Name: setA [C]

Synonym: Dgeo_1027

Alternate gene names: 94985132

Gene position: 1098950-1098468 (Counterclockwise)

Preceding gene: 94985142

Following gene: 94985131

Centisome position: 44.54

GC content: 66.25

Gene sequence:

>483_bases
GTGCTACACGGGACCGACGCCCAGGTCGGCTTTCTGGTGGGCCTGTGTGCGCTGCTGGAGATTCCGGTCATGCTGGCCTT
CGTGGTGGTTCGCCGCCTGCCCGCCACCGAACGGCTGGTGAAATACGCGTTGGCCCTGTTTGTGCTGCATTTTGCGCTCC
TGTACCTTGCGGCGGGAATGCCGCTCCTGACCCTCACGCAGGGGGTGCGGGCGGTGGTGATCGCGGTGATGGCGGGGCTG
GGAATGGCCTATTTTCAGGAGCTGATGCCCGGCCGCCTGGCTGCGGCCACCACCCTCTTTGCCAACACCACCAACCTCGG
GGCCATGCTCGCGGGGATCGTGTCGGGGGCCTGCGCACAACTGTTTGGCTACCGGGCGGTGTTCCTGCTGTGCGGGCTGC
TGACGCTGGGGGCCTGGCTGGTGATGGCGGTGGTCACACGTCGCCCGGCGAACCGAACAAAGGAAGCCGCAAGGAGAGCA
TAA

Upstream 100 bases:

>100_bases
CCCCTGGTCTGGGTCGCCTTTGCCTTTGTGCTGTATGGCATGAGCATGAGCATGGGCATGACGATGTTTCCGCTGCTAGT
TTCCGCTGCTAATCACCAAG

Downstream 100 bases:

>100_bases
AGCGAACTTCACAGCCTGCCCATCCTGCCTTCCCCCACAGCATGAAGACTGGGTCAGCACCCGATGAGACAGGGTGGGTC
GAAGCGAGGGAGGCTGAAGA

Product: hypothetical protein

Products: lactose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MLHGTDAQVGFLVGLCALLEIPVMLAFVVVRRLPATERLVKYALALFVLHFALLYLAAGMPLLTLTQGVRAVVIAVMAGL
GMAYFQELMPGRLAAATTLFANTTNLGAMLAGIVSGACAQLFGYRAVFLLCGLLTLGAWLVMAVVTRRPANRTKEAARRA

Sequences:

>Translated_160_residues
MLHGTDAQVGFLVGLCALLEIPVMLAFVVVRRLPATERLVKYALALFVLHFALLYLAAGMPLLTLTQGVRAVVIAVMAGL
GMAYFQELMPGRLAAATTLFANTTNLGAMLAGIVSGACAQLFGYRAVFLLCGLLTLGAWLVMAVVTRRPANRTKEAARRA
>Mature_160_residues
MLHGTDAQVGFLVGLCALLEIPVMLAFVVVRRLPATERLVKYALALFVLHFALLYLAAGMPLLTLTQGVRAVVIAVMAGL
GMAYFQELMPGRLAAATTLFANTTNLGAMLAGIVSGACAQLFGYRAVFLLCGLLTLGAWLVMAVVTRRPANRTKEAARRA

Specific function: Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Set transporter family [H]

Homologues:

Organism=Escherichia coli, GI48994875, Length=133, Percent_Identity=43.609022556391, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1790091, Length=131, Percent_Identity=37.4045801526718, Blast_Score=77, Evalue=4e-16,
Organism=Escherichia coli, GI1788495, Length=128, Percent_Identity=38.28125, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 17022; Mature: 17022

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHGTDAQVGFLVGLCALLEIPVMLAFVVVRRLPATERLVKYALALFVLHFALLYLAAGM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLTLTQGVRAVVIAVMAGLGMAYFQELMPGRLAAATTLFANTTNLGAMLAGIVSGACAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGYRAVFLLCGLLTLGAWLVMAVVTRRPANRTKEAARRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MLHGTDAQVGFLVGLCALLEIPVMLAFVVVRRLPATERLVKYALALFVLHFALLYLAAGM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLTLTQGVRAVVIAVMAGLGMAYFQELMPGRLAAATTLFANTTNLGAMLAGIVSGACAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGYRAVFLLCGLLTLGAWLVMAVVTRRPANRTKEAARRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: lactose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: lactose [Cytoplasm] + Proton [Periplasm] = lactose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]