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The map label for this gene is yezC [H]

Identifier: 94985092

GI number: 94985092

Start: 1058503

End: 1058964

Strand: Reverse

Name: yezC [H]

Synonym: Dgeo_0987

Alternate gene names: 94985092

Gene position: 1058964-1058503 (Counterclockwise)

Preceding gene: 94985095

Following gene: 94985083

Centisome position: 42.92

GC content: 63.64

Gene sequence:

>462_bases
ATGAAGCAGCACGGCAGCTCACTCGACTCCCTTGATCACCGCATCCTGGAAGAATTGCAAAGCGACGCGCGCCTGAGCAT
GCGCGAACTCGGCCGCCGCGTCGGCCTCTCGGCGCCGGCTGTCACCGAACGGGTCCGGCGCCTCGAAGACGCGGGGGTGA
TTCTGGGGTACGGCATCCGGGTGGCCTCCAAGCCCCTTGGGCGCACCATCACGGCGTTCATCGGCGTTCAAGACAGCGGG
CGCAATGATCCCACCCTGGTTCGCTGGGCCAAGAAACACGACGGCGTGCTGGAATGCCACAGCGTCACCGGCGACAATTC
CTGCATCCTGAAAGTCGCCGTGCCGGACGTAGCCGCGCTCGAAGCGCTGCTGGGCGAGTTGATTCAGATGGGCTTTACCT
GCGACACCAGCATTGTGCTGAGTACACCACTGGAGGGAAAGACGCTGTTGCCGCCAAAGTGA

Upstream 100 bases:

>100_bases
AGCTCCTTTGGAAGGCGCGCAGGACGCCTGCATGCCGCCTCTCTCCACACACGAAGCTGGCAAACGCCACCCCTCACCTT
GCAAACGTTAAGATAGATTC

Downstream 100 bases:

>100_bases
GCCTCAGCTCGCTGCCCTCTGCGTATGCGCCGCATACCTTTGCAAGAGGTCCCAGCCCGCCCCGCTGGCCATCACCTCGC
GTGCTCGGGCCACGCCCTGC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MKQHGSSLDSLDHRILEELQSDARLSMRELGRRVGLSAPAVTERVRRLEDAGVILGYGIRVASKPLGRTITAFIGVQDSG
RNDPTLVRWAKKHDGVLECHSVTGDNSCILKVAVPDVAALEALLGELIQMGFTCDTSIVLSTPLEGKTLLPPK

Sequences:

>Translated_153_residues
MKQHGSSLDSLDHRILEELQSDARLSMRELGRRVGLSAPAVTERVRRLEDAGVILGYGIRVASKPLGRTITAFIGVQDSG
RNDPTLVRWAKKHDGVLECHSVTGDNSCILKVAVPDVAALEALLGELIQMGFTCDTSIVLSTPLEGKTLLPPK
>Mature_153_residues
MKQHGSSLDSLDHRILEELQSDARLSMRELGRRVGLSAPAVTERVRRLEDAGVILGYGIRVASKPLGRTITAFIGVQDSG
RNDPTLVRWAKKHDGVLECHSVTGDNSCILKVAVPDVAALEALLGELIQMGFTCDTSIVLSTPLEGKTLLPPK

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=129, Percent_Identity=40.3100775193798, Blast_Score=86, Evalue=8e-19,
Organism=Escherichia coli, GI1790182, Length=141, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR000835
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16524; Mature: 16524

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQHGSSLDSLDHRILEELQSDARLSMRELGRRVGLSAPAVTERVRRLEDAGVILGYGIR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCE
VASKPLGRTITAFIGVQDSGRNDPTLVRWAKKHDGVLECHSVTGDNSCILKVAVPDVAAL
ECCCCCCCEEEEEEECCCCCCCCCCEEEEHHHCCCEEEEEECCCCCCEEEEEECCCHHHH
EALLGELIQMGFTCDTSIVLSTPLEGKTLLPPK
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKQHGSSLDSLDHRILEELQSDARLSMRELGRRVGLSAPAVTERVRRLEDAGVILGYGIR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCE
VASKPLGRTITAFIGVQDSGRNDPTLVRWAKKHDGVLECHSVTGDNSCILKVAVPDVAAL
ECCCCCCCEEEEEEECCCCCCCCCCEEEEHHHCCCEEEEEECCCCCCEEEEEECCCHHHH
EALLGELIQMGFTCDTSIVLSTPLEGKTLLPPK
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]