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The map label for this gene is metX [H]

Identifier: 94984624

GI number: 94984624

Start: 544759

End: 545769

Strand: Reverse

Name: metX [H]

Synonym: Dgeo_0517

Alternate gene names: 94984624

Gene position: 545769-544759 (Counterclockwise)

Preceding gene: 94984625

Following gene: 94984623

Centisome position: 22.12

GC content: 68.35

Gene sequence:

>1011_bases
ATGACCGCTTTGATCTCCCAGCCGGACCTGCTTCCCCCGCCGGCGCCGGAGCGATGTCCGCCGCAACAGACGGCGCGGCT
GTTCCGCGAGACACCGCTGCTCCTGGATTGCGGGCAGGTGGTCCAAGACGTGCGGGTGGCCTACCACACCTACGGGACGC
CGTCTGACCACGCGATTCTGGTGCTGCACGCCCTGACGGGCACAAGCGCCGTACACGAGTGGTGGCCGGACTTTCTGGGC
GAGGGCAAGCCGCTAGACCCCACCCGCGACTACATTGTCTGCGCGAATGTGCTGGGCGGCTGCGCGGGCAGCACGGGACC
GGCGGAGCTGCCCCGGGTCAACGGCGAGGATCCGCCCCTCACCCTGCGCGACATGGCGCGGGTGGGGCGCGCCCTGCTGG
AAGAGCTGGGCGTGCGGCGCGTCTCGGTCATCGGCGCCAGCATGGGGGGGATGCTGGCCTATGCCTGGCTCCTGGAATGC
CCGGACCTGGTGGACCGAGCGGTGATCATCGGCGCTCCGGCCCGCCACTCCCCTTGGGCCATCGGACTGAACACAGCCGC
ACGGAATGCTATCCGCGCGGCGCCGGGTGGTGAGGGCCTGAAGGTTGCCCGGCAGATCGCCATGTTGAGCTACCGCAGCC
CCGAGAGCTTCGCGCTCACGCAGTCGGGCTGGGGCACGCGGCGGCCTGGCACACCAGATATCACGACCTATCTGGAACAC
CAGGGCGAGAAGCTCTCGACCCGCTTCTGCGAGCGCAGCTACCTGGCCCTGACCGGCGCGATGGACCGCTTTCAGCCCAC
CGACGCCGAACTGCGGAGTATTCGCGTACCGGTGCTGGTGGTGGGGATCTCCAGTGACGTGCTGTATCCACCCGCCGAGG
TACGAACTTACGCGGGTCTGCTTCCACGCGGCCAGTATCTGGAACTGCAGAGCCCTCACGGTCACGACGCTTTCCTGATC
GACCCACAAGGGTTACCGGAGGCGGCAGCCGCCTTCCTGCACGGAGCCTGA

Upstream 100 bases:

>100_bases
CGGGACTGGTGCGCGTGTCGGTGGGGATCGAGCACATTGACGACATCCGCGAGGACTTTGCGCAGGCACTGGCCACCGCG
CTGGTGGACGCGGAGGGCGC

Downstream 100 bases:

>100_bases
CTCCGGCTCACCGGTTCGCTGTCCGCTCCAGACTGCCCGGGGTGCGCCGTGGCATCATAGACGACGTGCAGGCCAGCCAG
AGAGAGCCCTCTTTGCAAGA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTALISQPDLLPPPAPERCPPQQTARLFRETPLLLDCGQVVQDVRVAYHTYGTPSDHAILVLHALTGTSAVHEWWPDFLG
EGKPLDPTRDYIVCANVLGGCAGSTGPAELPRVNGEDPPLTLRDMARVGRALLEELGVRRVSVIGASMGGMLAYAWLLEC
PDLVDRAVIIGAPARHSPWAIGLNTAARNAIRAAPGGEGLKVARQIAMLSYRSPESFALTQSGWGTRRPGTPDITTYLEH
QGEKLSTRFCERSYLALTGAMDRFQPTDAELRSIRVPVLVVGISSDVLYPPAEVRTYAGLLPRGQYLELQSPHGHDAFLI
DPQGLPEAAAAFLHGA

Sequences:

>Translated_336_residues
MTALISQPDLLPPPAPERCPPQQTARLFRETPLLLDCGQVVQDVRVAYHTYGTPSDHAILVLHALTGTSAVHEWWPDFLG
EGKPLDPTRDYIVCANVLGGCAGSTGPAELPRVNGEDPPLTLRDMARVGRALLEELGVRRVSVIGASMGGMLAYAWLLEC
PDLVDRAVIIGAPARHSPWAIGLNTAARNAIRAAPGGEGLKVARQIAMLSYRSPESFALTQSGWGTRRPGTPDITTYLEH
QGEKLSTRFCERSYLALTGAMDRFQPTDAELRSIRVPVLVVGISSDVLYPPAEVRTYAGLLPRGQYLELQSPHGHDAFLI
DPQGLPEAAAAFLHGA
>Mature_335_residues
TALISQPDLLPPPAPERCPPQQTARLFRETPLLLDCGQVVQDVRVAYHTYGTPSDHAILVLHALTGTSAVHEWWPDFLGE
GKPLDPTRDYIVCANVLGGCAGSTGPAELPRVNGEDPPLTLRDMARVGRALLEELGVRRVSVIGASMGGMLAYAWLLECP
DLVDRAVIIGAPARHSPWAIGLNTAARNAIRAAPGGEGLKVARQIAMLSYRSPESFALTQSGWGTRRPGTPDITTYLEHQ
GEKLSTRFCERSYLALTGAMDRFQPTDAELRSIRVPVLVVGISSDVLYPPAEVRTYAGLLPRGQYLELQSPHGHDAFLID
PQGLPEAAAAFLHGA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=217, Percent_Identity=35.0230414746544, Blast_Score=126, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 36246; Mature: 36115

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALISQPDLLPPPAPERCPPQQTARLFRETPLLLDCGQVVQDVRVAYHTYGTPSDHAIL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCCEEE
VLHALTGTSAVHEWWPDFLGEGKPLDPTRDYIVCANVLGGCAGSTGPAELPRVNGEDPPL
EEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCC
TLRDMARVGRALLEELGVRRVSVIGASMGGMLAYAWLLECPDLVDRAVIIGAPARHSPWA
CHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCEE
IGLNTAARNAIRAAPGGEGLKVARQIAMLSYRSPESFALTQSGWGTRRPGTPDITTYLEH
EECCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHH
QGEKLSTRFCERSYLALTGAMDRFQPTDAELRSIRVPVLVVGISSDVLYPPAEVRTYAGL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCEEEEEECCCCCCCCHHHHHHHHC
LPRGQYLELQSPHGHDAFLIDPQGLPEAAAAFLHGA
CCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TALISQPDLLPPPAPERCPPQQTARLFRETPLLLDCGQVVQDVRVAYHTYGTPSDHAIL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCCCEEE
VLHALTGTSAVHEWWPDFLGEGKPLDPTRDYIVCANVLGGCAGSTGPAELPRVNGEDPPL
EEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCCCCCCCCCCCCCCCCCCCCC
TLRDMARVGRALLEELGVRRVSVIGASMGGMLAYAWLLECPDLVDRAVIIGAPARHSPWA
CHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCEE
IGLNTAARNAIRAAPGGEGLKVARQIAMLSYRSPESFALTQSGWGTRRPGTPDITTYLEH
EECCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHH
QGEKLSTRFCERSYLALTGAMDRFQPTDAELRSIRVPVLVVGISSDVLYPPAEVRTYAGL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCEEEEEECCCCCCCCHHHHHHHHC
LPRGQYLELQSPHGHDAFLIDPQGLPEAAAAFLHGA
CCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]