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The map label for this gene is moeZ [H]

Identifier: 94984284

GI number: 94984284

Start: 164378

End: 165118

Strand: Reverse

Name: moeZ [H]

Synonym: Dgeo_0176

Alternate gene names: 94984284

Gene position: 165118-164378 (Counterclockwise)

Preceding gene: 94984288

Following gene: 94984283

Centisome position: 6.69

GC content: 71.12

Gene sequence:

>741_bases
ATGACCCCATCCCTCTCCCGAACCGAACTGCGGCGCTACTCGCGGCAACTCCTGGTGCCTGAATGGCAGGGCGCGGGCGC
TCAGGAGCGGGTGAGGGGAGCAGCCGTGCTGGTGGTCGGCGCAGGCGGACTGGGCGGCCCGGTCATCCTCCAGCTCGCCG
GAGCCGGCGTGGGACGGTTGGTGATCGCGGACGGGGACACGGTCGACCTCAGCAACCTGCATCGCCAGACCCAGTTCAGC
CTGGCGGATGTGGGCCGGCCCAAGGCGGAGGTGGCAGCCGCGCGAGCACAGGCCCTCAATCCCTTTGTCCGGGTGGAGGT
GGCCCCACGGTTAGACGCTGGGAACGCGGACACCCTGCTTGCGGGCGTGGACCTGATTGTGGACGCGACCGACAACTTCG
AGGCGCGTTACGCCATTGCCGACGCCTGCGGGCGCGCCCAGCGCGAGTGGGTGTGGGGCGCGGCCAGCGGCACAAGCGGG
CTGGTGAGCGTGTTTGGGCCGGACCTTGGTCTGCGCGACGTGTTCCCCGACCCCGGCGACGCGGCGTCTTGCGATGAGGC
CGGAGTCCTGGGGCCACTGCCCAACGTGGTCGGCGGCGTGATGGCGCTCGAAGCCCTCAAGCTGTTGGGCGGCGTGGGCG
AGCCGCTGCGCGGGCGGCTGTGGACCTTCGACGCCCTGAGTGGACGTGTTCGGGTGCTCCATCTGCGGGGCACGGGAGGC
CAAGTGGGCGGCCGAGCGTAA

Upstream 100 bases:

>100_bases
CACGCCCGCCACGAGAGAACCGAGCAGATAGGAGACGAGAGCGACCAGGGCGAGCATCCCGCGCATTCTAGAGTCTGGCA
TCCCGTTCTAGACTTCCCGC

Downstream 100 bases:

>100_bases
CCCTGCGGCTTGCATCCGGCCAAACGTGTGTTACTGTGCATTTGAGCCAACAATTCGCTCAAATCCACCTTTCGGAGGTC
TATGGCATGGCCAGAACGTC

Product: UBA/THIF-type NAD/FAD binding fold

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTPSLSRTELRRYSRQLLVPEWQGAGAQERVRGAAVLVVGAGGLGGPVILQLAGAGVGRLVIADGDTVDLSNLHRQTQFS
LADVGRPKAEVAAARAQALNPFVRVEVAPRLDAGNADTLLAGVDLIVDATDNFEARYAIADACGRAQREWVWGAASGTSG
LVSVFGPDLGLRDVFPDPGDAASCDEAGVLGPLPNVVGGVMALEALKLLGGVGEPLRGRLWTFDALSGRVRVLHLRGTGG
QVGGRA

Sequences:

>Translated_246_residues
MTPSLSRTELRRYSRQLLVPEWQGAGAQERVRGAAVLVVGAGGLGGPVILQLAGAGVGRLVIADGDTVDLSNLHRQTQFS
LADVGRPKAEVAAARAQALNPFVRVEVAPRLDAGNADTLLAGVDLIVDATDNFEARYAIADACGRAQREWVWGAASGTSG
LVSVFGPDLGLRDVFPDPGDAASCDEAGVLGPLPNVVGGVMALEALKLLGGVGEPLRGRLWTFDALSGRVRVLHLRGTGG
QVGGRA
>Mature_245_residues
TPSLSRTELRRYSRQLLVPEWQGAGAQERVRGAAVLVVGAGGLGGPVILQLAGAGVGRLVIADGDTVDLSNLHRQTQFSL
ADVGRPKAEVAAARAQALNPFVRVEVAPRLDAGNADTLLAGVDLIVDATDNFEARYAIADACGRAQREWVWGAASGTSGL
VSVFGPDLGLRDVFPDPGDAASCDEAGVLGPLPNVVGGVMALEALKLLGGVGEPLRGRLWTFDALSGRVRVLHLRGTGGQ
VGGRA

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=232, Percent_Identity=42.2413793103448, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI38045948, Length=181, Percent_Identity=37.5690607734807, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI23510338, Length=156, Percent_Identity=30.1282051282051, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI23510340, Length=156, Percent_Identity=30.1282051282051, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=38.8, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI87082356, Length=237, Percent_Identity=39.2405063291139, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17540406, Length=239, Percent_Identity=38.9121338912134, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71984476, Length=69, Percent_Identity=47.8260869565217, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=245, Percent_Identity=37.1428571428571, Blast_Score=139, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322639, Length=170, Percent_Identity=28.8235294117647, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582879, Length=242, Percent_Identity=37.603305785124, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24660640, Length=141, Percent_Identity=35.4609929078014, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641311, Length=227, Percent_Identity=31.2775330396476, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 25417; Mature: 25286

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSLSRTELRRYSRQLLVPEWQGAGAQERVRGAAVLVVGAGGLGGPVILQLAGAGVGRL
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEEEEECCCCCCCEEEEECCCCCEEE
VIADGDTVDLSNLHRQTQFSLADVGRPKAEVAAARAQALNPFVRVEVAPRLDAGNADTLL
EEECCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEE
AGVDLIVDATDNFEARYAIADACGRAQREWVWGAASGTSGLVSVFGPDLGLRDVFPDPGD
ECEEEEEECCCCCCEEEHHHHHHCCCHHHEEEEECCCCCCEEEECCCCCCCCCCCCCCCC
AASCDEAGVLGPLPNVVGGVMALEALKLLGGVGEPLRGRLWTFDALSGRVRVLHLRGTGG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEECCCC
QVGGRA
CCCCCC
>Mature Secondary Structure 
TPSLSRTELRRYSRQLLVPEWQGAGAQERVRGAAVLVVGAGGLGGPVILQLAGAGVGRL
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEEEEECCCCCCCEEEEECCCCCEEE
VIADGDTVDLSNLHRQTQFSLADVGRPKAEVAAARAQALNPFVRVEVAPRLDAGNADTLL
EEECCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEE
AGVDLIVDATDNFEARYAIADACGRAQREWVWGAASGTSGLVSVFGPDLGLRDVFPDPGD
ECEEEEEECCCCCCEEEHHHHHHCCCHHHEEEEECCCCCCEEEECCCCCCCCCCCCCCCC
AASCDEAGVLGPLPNVVGGVMALEALKLLGGVGEPLRGRLWTFDALSGRVRVLHLRGTGG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEECCCC
QVGGRA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]