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The map label for this gene is ycfH [C]

Identifier: 94984259

GI number: 94984259

Start: 141148

End: 141978

Strand: Reverse

Name: ycfH [C]

Synonym: Dgeo_0151

Alternate gene names: 94984259

Gene position: 141978-141148 (Counterclockwise)

Preceding gene: 94984263

Following gene: 94984257

Centisome position: 5.75

GC content: 67.99

Gene sequence:

>831_bases
ATGATCGACACCCACTGCCACCTTGACTACCTCGACGACCCAGCCTCGGCGCGGGGAGAATTGGGCCTAAGCGGGATGGT
CTGTATCGGGGCCAGCCTGGAACACGCCCGGAACGCGGTGGCGCTGGCCGAGCAGTTCCCCGACGTGTGGGCAACGGTGG
GCTTGCATCCCACCGACACCGCCGAGGACGGGCCGCAGCTGCGGGCTGAGCTGGAGGCGCTGGCACAACATCCGCGCGTG
GTGGGCATCGGGGAGAGCGGGCTGGATGACTACTGGGACGACACGCGGCGCGCGGCCCAGGTGTCCGCCTTCGAGTGGCA
GCTCGAGCTGGCGCGGCGCACCGGCAAGCCGCTGGTGATTCACGTGCGCGACAAGGCCGGGCAGGACTCCGCACAACAGG
GCGTGATGGAGATCCTCAAGAGCTGGCCGGACGTGCCGGTGATTCTCCACTGCTTCAGCGGCCATCCTGGCCTGCTGGCC
TACGGGCTAGAGCGCGGCGCATATTTCGGGTTCGCGGGCAACACCACCTACAAGAACGCCCAGGCAATTCAGCAGGCAGC
CCGGCAGGTGCCGCAAGACCGCCTGCTGATAGAAACCGACGCGCCCTTCCTGGCCCCGGTCCCAAAGCGCGGCCAGCCCA
ACCGCCCCGGCTACGTGCGCTATACGCTGGACTTTATCGCGGCCCTGCGTGGGGTCGAAGCGGCGGTCTTGGAGCAGGTC
ACCGATGCCAACGCCCGCCGGGTTTACCGCCTCCCAGACAGAGAGCAGCAACATACCTCCTCTGCCTCAGAGCGCGAGGG
CCACGCCGCTACCACCAACCCCGGCGCTTGA

Upstream 100 bases:

>100_bases
CGCTGACGGGAGGTGAGGCGGCAGGGAGGACCGCCGAGTCCCAAGCCAAAAAGCAGCTCCTCCCACAACCTGCGGCCCAC
CACCCTCTACCCTTTCTCCC

Downstream 100 bases:

>100_bases
AGGAGTACGCCAGCCACACACCAATCACCAAAAAACTGAGCCAGGCAAAAGCATACCCGTAGCGGGTGTGCAGCTCCGGC
ATATGTTCGAAATTCATGCC

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MIDTHCHLDYLDDPASARGELGLSGMVCIGASLEHARNAVALAEQFPDVWATVGLHPTDTAEDGPQLRAELEALAQHPRV
VGIGESGLDDYWDDTRRAAQVSAFEWQLELARRTGKPLVIHVRDKAGQDSAQQGVMEILKSWPDVPVILHCFSGHPGLLA
YGLERGAYFGFAGNTTYKNAQAIQQAARQVPQDRLLIETDAPFLAPVPKRGQPNRPGYVRYTLDFIAALRGVEAAVLEQV
TDANARRVYRLPDREQQHTSSASEREGHAATTNPGA

Sequences:

>Translated_276_residues
MIDTHCHLDYLDDPASARGELGLSGMVCIGASLEHARNAVALAEQFPDVWATVGLHPTDTAEDGPQLRAELEALAQHPRV
VGIGESGLDDYWDDTRRAAQVSAFEWQLELARRTGKPLVIHVRDKAGQDSAQQGVMEILKSWPDVPVILHCFSGHPGLLA
YGLERGAYFGFAGNTTYKNAQAIQQAARQVPQDRLLIETDAPFLAPVPKRGQPNRPGYVRYTLDFIAALRGVEAAVLEQV
TDANARRVYRLPDREQQHTSSASEREGHAATTNPGA
>Mature_276_residues
MIDTHCHLDYLDDPASARGELGLSGMVCIGASLEHARNAVALAEQFPDVWATVGLHPTDTAEDGPQLRAELEALAQHPRV
VGIGESGLDDYWDDTRRAAQVSAFEWQLELARRTGKPLVIHVRDKAGQDSAQQGVMEILKSWPDVPVILHCFSGHPGLLA
YGLERGAYFGFAGNTTYKNAQAIQQAARQVPQDRLLIETDAPFLAPVPKRGQPNRPGYVRYTLDFIAALRGVEAAVLEQV
TDANARRVYRLPDREQQHTSSASEREGHAATTNPGA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=279, Percent_Identity=32.9749103942652, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI14042943, Length=274, Percent_Identity=27.007299270073, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI225903439, Length=251, Percent_Identity=27.0916334661355, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=24.5136186770428, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=24.2537313432836, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=24.2537313432836, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=24.4525547445255, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=32.4427480916031, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI48994985, Length=245, Percent_Identity=32.2448979591837, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082439, Length=260, Percent_Identity=28.0769230769231, Blast_Score=95, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=27.8810408921933, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=272, Percent_Identity=26.8382352941176, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=189, Percent_Identity=30.6878306878307, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648690, Length=192, Percent_Identity=34.375, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24586117, Length=220, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221330018, Length=203, Percent_Identity=30.5418719211823, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30149; Mature: 30149

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00889 CNMP_BINDING_2 ; PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTHCHLDYLDDPASARGELGLSGMVCIGASLEHARNAVALAEQFPDVWATVGLHPTDT
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCCC
AEDGPQLRAELEALAQHPRVVGIGESGLDDYWDDTRRAAQVSAFEWQLELARRTGKPLVI
CCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
HVRDKAGQDSAQQGVMEILKSWPDVPVILHCFSGHPGLLAYGLERGAYFGFAGNTTYKNA
EECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEHHCCCEEEEECCCCCCHHH
QAIQQAARQVPQDRLLIETDAPFLAPVPKRGQPNRPGYVRYTLDFIAALRGVEAAVLEQV
HHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHH
TDANARRVYRLPDREQQHTSSASEREGHAATTNPGA
HCCCCCEEEECCCHHHHHHCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MIDTHCHLDYLDDPASARGELGLSGMVCIGASLEHARNAVALAEQFPDVWATVGLHPTDT
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCCC
AEDGPQLRAELEALAQHPRVVGIGESGLDDYWDDTRRAAQVSAFEWQLELARRTGKPLVI
CCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
HVRDKAGQDSAQQGVMEILKSWPDVPVILHCFSGHPGLLAYGLERGAYFGFAGNTTYKNA
EECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEHHCCCEEEEECCCCCCHHH
QAIQQAARQVPQDRLLIETDAPFLAPVPKRGQPNRPGYVRYTLDFIAALRGVEAAVLEQV
HHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHH
TDANARRVYRLPDREQQHTSSASEREGHAATTNPGA
HCCCCCEEEECCCHHHHHHCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]