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The map label for this gene is aidB [H]

Identifier: 94314812

GI number: 94314812

Start: 91347

End: 93143

Strand: Direct

Name: aidB [H]

Synonym: Rmet_5893

Alternate gene names: 94314812

Gene position: 91347-93143 (Clockwise)

Preceding gene: 94314807

Following gene: 94314813

Centisome position: 3.54

GC content: 68.89

Gene sequence:

>1797_bases
ATGCCGACCAGCGCCGCGCGCCCAGCCGCGTCCACCACCGCGTACCCCGAAGTTGCCGCGCATCCGGTGCCAGATCGCCA
TGGCGCGAGTCTGTTCACGGCCGATCCGGACCTGCGCGCGCTGCTGCCGCTCTACCTGCCTGCTGACCTGTTCAACCACC
TGCTGCCGCACCTCGAGCGCATGGGCGCGCTGGCCGGCGGCGTGCTCGACGAACTGGCCAACGAGGCCGATCACGCGCCG
CCCACGCTGTCGCACCGCATCCGCACCGGCCTGGATGCCCAGCGCATCCATAAGCATCCGTCCTACGTGGAACTGGAGCG
CGTGGCGTTCTCGGAATTCGGGCTGGCTGCGGCGTCGCATCGCGGCGGCGTGCTCGGCTGGGACAAGCCAATGCCCCCTG
CCGCGAAGTACGCACTGACCTACCTGTTCGTGCAGGCCGAATTCGGCCTGTGCTGCCCGCTGTCGATGACCGATTCGCTG
ACGCGCACGCTGCGCAAGTTCGGCGATCCGGCGCTGGTCGACCGCTTCCTGCCGAACCTGACCACGCAGGTGTTCGACGA
CCTTTACCAGGGCGCGATGTTCATGACCGAACAGGGGGCAGGCTCTGACGTCGCCGCCACGACCACCCGTGCGATTCGCG
ACGGCAACGCCGAGGGTGGCTGGCGTCTGGTGGGCGACAAGTGGTTCTGCTCGAATCCCGATGCCGCGCTGGCGATGGTG
TTGGCGCGGGTGGAGGAAGCCGACGGTTCGGCCGTTGCCGGTATCAAGGGCGTCTCGCTGTTCCTGTTGCCGCGCACGCT
GGCGGATGGCAGCGCCAACCACTTCCGCATCATCCGTCTCAAGGACAAGCTCGGCACACGCTCGATGGCTAGCGGCGAGA
TCCGGCTGGAGGGCGCGCACGCCTACATGGTTGGCGAACTGGGCCGTGGTTTCGTGCAGATGGCCGACATGATCAACAAC
TCGCGCCTGTCCAACGGCGTGCGCGCGGCCGGCCTGATGCGCCGGGCGTTGACCGAGGGCCAGTTCATCGCCCGCGAGCG
CCGCGCGTTCGGCAAGCGCCTGGCGGACATGCCGCTGATGCGTCGCCAGTTGCTGAAGCTGACGCTGCCCACGGAGCAGG
CGCGCACGATGGTGTTCCAGACTGCCGAAGCCCTGCGCCGTGCCGACGCGGGCGATGCCGACGCCTATCCGCTGATGCGC
ATCCTGACACCGCTGATCAAGTTCCGCGCCTGCCGAGACGCACGCAAGGTCACGGGTGATGCGATGGAGATCCGCGGCGG
CTGCGGCTACATCGAGGAATGGAGCGACCCGCGCCTCGTGCGCGACGCGCATCTCGGTTCGATCTGGGAAGGCACGAGCA
ATATCGTCGCACTCGACGTGCTGCGCGCAATTCGCCGCGAGGGCTCGCTGCCCGTGTTGCAGGCACACCTGCAGGCGCTG
CTTGGCGATACGCCGATGCACGCCACCGCGCGCGCCACGTTCGATCTGGCCCTGGCCAACACCGTCGCGCTGGCGACCCG
TGCGGCAGAAGCCGGGGCCGATGGCGACGTGCTGGCGCGTCAGGCGGCTTCCGCGCTGTATCACGTGACCAGTGCCGTCG
CCATGGCATGGGAAGCCGGCCAGATCGGTTCGGTTCGCCGGATGCGGCTGGCGCAGTTGGTGCTGGTGCATCGCGTGCTG
CCGCAGGATCCGCTCGGCGGCGGCGTCGAGCCCGAGTGGCTGGCCGAAACCGTGGAGCCGCCCGCCGATGGCGTGGTGCG
CGCGGCGGGGCCCGTGGACCAGATCAACGTGTTCTGA

Upstream 100 bases:

>100_bases
ACACGAATCGTTGGGGTTTGAATAATGGACGCAAACCATCCCGCCCGACAGCCGCCCGACAGGCATCGTGTCCAGGACGG
GGACTTCCAGGAGACGATTC

Downstream 100 bases:

>100_bases
CGGCTCACCCAGAGAACACCCAGGCAGTACGGTGCGCCCGCAACGGCGCACCTCGCGCGCCCGCGGCGCGCATTCCAAAC
ATAAAAAGCTTTACCGGAGA

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MPTSAARPAASTTAYPEVAAHPVPDRHGASLFTADPDLRALLPLYLPADLFNHLLPHLERMGALAGGVLDELANEADHAP
PTLSHRIRTGLDAQRIHKHPSYVELERVAFSEFGLAAASHRGGVLGWDKPMPPAAKYALTYLFVQAEFGLCCPLSMTDSL
TRTLRKFGDPALVDRFLPNLTTQVFDDLYQGAMFMTEQGAGSDVAATTTRAIRDGNAEGGWRLVGDKWFCSNPDAALAMV
LARVEEADGSAVAGIKGVSLFLLPRTLADGSANHFRIIRLKDKLGTRSMASGEIRLEGAHAYMVGELGRGFVQMADMINN
SRLSNGVRAAGLMRRALTEGQFIARERRAFGKRLADMPLMRRQLLKLTLPTEQARTMVFQTAEALRRADAGDADAYPLMR
ILTPLIKFRACRDARKVTGDAMEIRGGCGYIEEWSDPRLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLQAHLQAL
LGDTPMHATARATFDLALANTVALATRAAEAGADGDVLARQAASALYHVTSAVAMAWEAGQIGSVRRMRLAQLVLVHRVL
PQDPLGGGVEPEWLAETVEPPADGVVRAAGPVDQINVF

Sequences:

>Translated_598_residues
MPTSAARPAASTTAYPEVAAHPVPDRHGASLFTADPDLRALLPLYLPADLFNHLLPHLERMGALAGGVLDELANEADHAP
PTLSHRIRTGLDAQRIHKHPSYVELERVAFSEFGLAAASHRGGVLGWDKPMPPAAKYALTYLFVQAEFGLCCPLSMTDSL
TRTLRKFGDPALVDRFLPNLTTQVFDDLYQGAMFMTEQGAGSDVAATTTRAIRDGNAEGGWRLVGDKWFCSNPDAALAMV
LARVEEADGSAVAGIKGVSLFLLPRTLADGSANHFRIIRLKDKLGTRSMASGEIRLEGAHAYMVGELGRGFVQMADMINN
SRLSNGVRAAGLMRRALTEGQFIARERRAFGKRLADMPLMRRQLLKLTLPTEQARTMVFQTAEALRRADAGDADAYPLMR
ILTPLIKFRACRDARKVTGDAMEIRGGCGYIEEWSDPRLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLQAHLQAL
LGDTPMHATARATFDLALANTVALATRAAEAGADGDVLARQAASALYHVTSAVAMAWEAGQIGSVRRMRLAQLVLVHRVL
PQDPLGGGVEPEWLAETVEPPADGVVRAAGPVDQINVF
>Mature_597_residues
PTSAARPAASTTAYPEVAAHPVPDRHGASLFTADPDLRALLPLYLPADLFNHLLPHLERMGALAGGVLDELANEADHAPP
TLSHRIRTGLDAQRIHKHPSYVELERVAFSEFGLAAASHRGGVLGWDKPMPPAAKYALTYLFVQAEFGLCCPLSMTDSLT
RTLRKFGDPALVDRFLPNLTTQVFDDLYQGAMFMTEQGAGSDVAATTTRAIRDGNAEGGWRLVGDKWFCSNPDAALAMVL
ARVEEADGSAVAGIKGVSLFLLPRTLADGSANHFRIIRLKDKLGTRSMASGEIRLEGAHAYMVGELGRGFVQMADMINNS
RLSNGVRAAGLMRRALTEGQFIARERRAFGKRLADMPLMRRQLLKLTLPTEQARTMVFQTAEALRRADAGDADAYPLMRI
LTPLIKFRACRDARKVTGDAMEIRGGCGYIEEWSDPRLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLQAHLQALL
GDTPMHATARATFDLALANTVALATRAAEAGADGDVLARQAASALYHVTSAVAMAWEAGQIGSVRRMRLAQLVLVHRVLP
QDPLGGGVEPEWLAETVEPPADGVVRAAGPVDQINVF

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=329, Percent_Identity=29.1793313069909, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI21361497, Length=336, Percent_Identity=26.1904761904762, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI226958414, Length=313, Percent_Identity=26.517571884984, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI226958412, Length=313, Percent_Identity=26.517571884984, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI4557233, Length=283, Percent_Identity=28.2685512367491, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4557235, Length=354, Percent_Identity=25.1412429378531, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI76496475, Length=354, Percent_Identity=25.1412429378531, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4501857, Length=361, Percent_Identity=24.9307479224377, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557231, Length=276, Percent_Identity=30.0724637681159, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI187960098, Length=276, Percent_Identity=30.0724637681159, Blast_Score=75, Evalue=3e-13,
Organism=Escherichia coli, GI87082384, Length=409, Percent_Identity=34.9633251833741, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI87081958, Length=309, Percent_Identity=27.831715210356, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=556, Percent_Identity=28.7769784172662, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI86563383, Length=516, Percent_Identity=29.2635658914729, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17508101, Length=318, Percent_Identity=25.7861635220126, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=297, Percent_Identity=26.5993265993266, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=360, Percent_Identity=30.8333333333333, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=363, Percent_Identity=24.7933884297521, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=314, Percent_Identity=31.2101910828025, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=286, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=212, Percent_Identity=24.5283018867925, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=276, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=313, Percent_Identity=25.5591054313099, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=272, Percent_Identity=26.8382352941176, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=299, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666513, Length=319, Percent_Identity=23.8244514106583, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=25.5072463768116, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355753, Length=308, Percent_Identity=27.5974025974026, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21356377, Length=319, Percent_Identity=26.3322884012539, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646207, Length=277, Percent_Identity=25.2707581227437, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=272, Percent_Identity=27.9411764705882, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 64646; Mature: 64515

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSAARPAASTTAYPEVAAHPVPDRHGASLFTADPDLRALLPLYLPADLFNHLLPHLER
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
MGALAGGVLDELANEADHAPPTLSHRIRTGLDAQRIHKHPSYVELERVAFSEFGLAAASH
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHCC
RGGVLGWDKPMPPAAKYALTYLFVQAEFGLCCPLSMTDSLTRTLRKFGDPALVDRFLPNL
CCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
TTQVFDDLYQGAMFMTEQGAGSDVAATTTRAIRDGNAEGGWRLVGDKWFCSNPDAALAMV
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEECCCCHHHHHHH
LARVEEADGSAVAGIKGVSLFLLPRTLADGSANHFRIIRLKDKLGTRSMASGEIRLEGAH
HHHHHHCCCCEEECCCCCEEEEEEHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCC
AYMVGELGRGFVQMADMINNSRLSNGVRAAGLMRRALTEGQFIARERRAFGKRLADMPLM
EEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
RRQLLKLTLPTEQARTMVFQTAEALRRADAGDADAYPLMRILTPLIKFRACRDARKVTGD
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
AMEIRGGCGYIEEWSDPRLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLQAHLQAL
HHEECCCCCCCCCCCCCCEEHHHCCCCHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LGDTPMHATARATFDLALANTVALATRAAEAGADGDVLARQAASALYHVTSAVAMAWEAG
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QIGSVRRMRLAQLVLVHRVLPQDPLGGGVEPEWLAETVEPPADGVVRAAGPVDQINVF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCC
>Mature Secondary Structure 
PTSAARPAASTTAYPEVAAHPVPDRHGASLFTADPDLRALLPLYLPADLFNHLLPHLER
CCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
MGALAGGVLDELANEADHAPPTLSHRIRTGLDAQRIHKHPSYVELERVAFSEFGLAAASH
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCHHHCC
RGGVLGWDKPMPPAAKYALTYLFVQAEFGLCCPLSMTDSLTRTLRKFGDPALVDRFLPNL
CCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
TTQVFDDLYQGAMFMTEQGAGSDVAATTTRAIRDGNAEGGWRLVGDKWFCSNPDAALAMV
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEECCCCHHHHHHH
LARVEEADGSAVAGIKGVSLFLLPRTLADGSANHFRIIRLKDKLGTRSMASGEIRLEGAH
HHHHHHCCCCEEECCCCCEEEEEEHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCC
AYMVGELGRGFVQMADMINNSRLSNGVRAAGLMRRALTEGQFIARERRAFGKRLADMPLM
EEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
RRQLLKLTLPTEQARTMVFQTAEALRRADAGDADAYPLMRILTPLIKFRACRDARKVTGD
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
AMEIRGGCGYIEEWSDPRLVRDAHLGSIWEGTSNIVALDVLRAIRREGSLPVLQAHLQAL
HHEECCCCCCCCCCCCCCEEHHHCCCCHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LGDTPMHATARATFDLALANTVALATRAAEAGADGDVLARQAASALYHVTSAVAMAWEAG
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
QIGSVRRMRLAQLVLVHRVLPQDPLGGGVEPEWLAETVEPPADGVVRAAGPVDQINVF
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]