Click here to switch to the map view.

The map label for this gene is allD [C]

Identifier: 94314014

GI number: 94314014

Start: 1785824

End: 1786834

Strand: Reverse

Name: allD [C]

Synonym: Rmet_5095

Alternate gene names: 94314014

Gene position: 1786834-1785824 (Counterclockwise)

Preceding gene: 94314015

Following gene: 94314004

Centisome position: 69.25

GC content: 64.79

Gene sequence:

>1011_bases
ATGTCGGAAACCATCCAGCTCTCGCTCGCGGAGGTACGCGAGCTTTCGCTCAACGTTCTGCAAACGAACGGCTACTCCGA
GGCGCACAGCAAGGCGATCACGGACGTGATCGTCGCGGGCCAGCGCGACGAGTGCCAGTCTCATGGCCTGTATCGCTTGC
TGGTCTGCGTTCATACCATTCGCAACGGGAAGGTGGATGGCCACGCGGTGCCGGAAGTCGTCGATCAGGCGAAAGCGATC
GTCCGGGTCGATGCCCGCTTTGGTAACTCGCTGCTGGCGTTTCAGACCGGCCTGCCGCATTTCATCCGGAAAGCCCGGGA
ATGCGGTTTGGCGGCCATGGCCATCAATCGCTGCTTTCACTTCTCCGCGCTCTGGCCCGAAGTGGAATCGCTGGCGAGCG
AAGGACTGGTCGCAATGGCCATGACGCCCAGCCACGCGTGGGTGGCCCCTGCCGGCGGAACCAAACCGGTATTCGGAACG
AATCCCCTGGCGTTCGCCTGGCCGCGTCCGGGCAGAACGCCATTTGTCTTCGACTTTGCGACCAGCGCGATCGCCAGAGG
CGATATCGAGCTTCATCGCCGGCAAGGCAAGGCGCTGCCGGAGGGGTGGGCCATCGATGCGGACGGGAACCCGACGACCG
ACCCGCTGGCGGCCCTGAAAGGCGCCATGCTGACGTTCGGCGGGCACAAGGGGTCTGCGTTGTCCGCGATGATCGAACTG
ATGGCCGGCCCGCTGATCGGCGACATGACCAGCGCCGAATCCATGGCGTTCGATGCGAGCGCGGGGGCCACGCCTTGTCA
TGGCGAACTGCTGCTGGCATTCGATCCCACCGTCTTTCTGGGCGATCGGGCCAGCGAGTACCTTGAGAAAGCCGAGAGCC
TGTTCGAGGCAATCACGAGCCAGGGCGCGCGCTTGCCGTCGCAACGCCGCTACGCCGCGCGAGCCAGGAGCGATGAGGCG
GGCGTGACGGTGCCACGGGCGCTGTACGAGGATCTGCTCAAGCTGCGATAG

Upstream 100 bases:

>100_bases
CAGCGTTTTCTTCGGCCCGTGGCACTTCAGGATGCGCCGGAGTGGCTGCTCCAGCGCGCGTGATATCTCACAGGCAACGA
TAAGGAGGCATGGCAGATCA

Downstream 100 bases:

>100_bases
CCGAGCCATCCTATGACGACGATTCGCGTACCGCCTCGGCTCGCGAATCGCCGGCGATTGGCGGCTTACTCGAAGTCTGG
CTCGCCCTGCCAGTCAAAGA

Product: malate/L-sulfolactate dehydrogenase

Products: Oxalureate; NAD(P)H. [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSETIQLSLAEVRELSLNVLQTNGYSEAHSKAITDVIVAGQRDECQSHGLYRLLVCVHTIRNGKVDGHAVPEVVDQAKAI
VRVDARFGNSLLAFQTGLPHFIRKARECGLAAMAINRCFHFSALWPEVESLASEGLVAMAMTPSHAWVAPAGGTKPVFGT
NPLAFAWPRPGRTPFVFDFATSAIARGDIELHRRQGKALPEGWAIDADGNPTTDPLAALKGAMLTFGGHKGSALSAMIEL
MAGPLIGDMTSAESMAFDASAGATPCHGELLLAFDPTVFLGDRASEYLEKAESLFEAITSQGARLPSQRRYAARARSDEA
GVTVPRALYEDLLKLR

Sequences:

>Translated_336_residues
MSETIQLSLAEVRELSLNVLQTNGYSEAHSKAITDVIVAGQRDECQSHGLYRLLVCVHTIRNGKVDGHAVPEVVDQAKAI
VRVDARFGNSLLAFQTGLPHFIRKARECGLAAMAINRCFHFSALWPEVESLASEGLVAMAMTPSHAWVAPAGGTKPVFGT
NPLAFAWPRPGRTPFVFDFATSAIARGDIELHRRQGKALPEGWAIDADGNPTTDPLAALKGAMLTFGGHKGSALSAMIEL
MAGPLIGDMTSAESMAFDASAGATPCHGELLLAFDPTVFLGDRASEYLEKAESLFEAITSQGARLPSQRRYAARARSDEA
GVTVPRALYEDLLKLR
>Mature_335_residues
SETIQLSLAEVRELSLNVLQTNGYSEAHSKAITDVIVAGQRDECQSHGLYRLLVCVHTIRNGKVDGHAVPEVVDQAKAIV
RVDARFGNSLLAFQTGLPHFIRKARECGLAAMAINRCFHFSALWPEVESLASEGLVAMAMTPSHAWVAPAGGTKPVFGTN
PLAFAWPRPGRTPFVFDFATSAIARGDIELHRRQGKALPEGWAIDADGNPTTDPLAALKGAMLTFGGHKGSALSAMIELM
AGPLIGDMTSAESMAFDASAGATPCHGELLLAFDPTVFLGDRASEYLEKAESLFEAITSQGARLPSQRRYAARARSDEAG
VTVPRALYEDLLKLR

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=340, Percent_Identity=28.5294117647059, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787020, Length=240, Percent_Identity=31.25, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790000, Length=338, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17507179, Length=347, Percent_Identity=25.0720461095101, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536633, Length=298, Percent_Identity=27.8523489932886, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI45553211, Length=283, Percent_Identity=30.0353356890459, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24667912, Length=283, Percent_Identity=30.0353356890459, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24667908, Length=283, Percent_Identity=30.0353356890459, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24667904, Length=283, Percent_Identity=30.0353356890459, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24648360, Length=266, Percent_Identity=26.6917293233083, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24658010, Length=306, Percent_Identity=25.4901960784314, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.154 [C]

Molecular weight: Translated: 36056; Mature: 35924

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETIQLSLAEVRELSLNVLQTNGYSEAHSKAITDVIVAGQRDECQSHGLYRLLVCVHTI
CCCCEEEHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHH
RNGKVDGHAVPEVVDQAKAIVRVDARFGNSLLAFQTGLPHFIRKARECGLAAMAINRCFH
HCCCCCCCHHHHHHHHHHHHEEEHHHHCCEEEEHHCCCHHHHHHHHHCCHHHHHHHHHHH
FSALWPEVESLASEGLVAMAMTPSHAWVAPAGGTKPVFGTNPLAFAWPRPGRTPFVFDFA
HHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCEEEEHH
TSAIARGDIELHRRQGKALPEGWAIDADGNPTTDPLAALKGAMLTFGGHKGSALSAMIEL
HHHHHHCCHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHEEECCCCCHHHHHHHHH
MAGPLIGDMTSAESMAFDASAGATPCHGELLLAFDPTVFLGDRASEYLEKAESLFEAITS
HHCCHHCCCCCHHHHEECCCCCCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHH
QGARLPSQRRYAARARSDEAGVTVPRALYEDLLKLR
CCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SETIQLSLAEVRELSLNVLQTNGYSEAHSKAITDVIVAGQRDECQSHGLYRLLVCVHTI
CCCEEEHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHH
RNGKVDGHAVPEVVDQAKAIVRVDARFGNSLLAFQTGLPHFIRKARECGLAAMAINRCFH
HCCCCCCCHHHHHHHHHHHHEEEHHHHCCEEEEHHCCCHHHHHHHHHCCHHHHHHHHHHH
FSALWPEVESLASEGLVAMAMTPSHAWVAPAGGTKPVFGTNPLAFAWPRPGRTPFVFDFA
HHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCEEEEHH
TSAIARGDIELHRRQGKALPEGWAIDADGNPTTDPLAALKGAMLTFGGHKGSALSAMIEL
HHHHHHCCHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHEEECCCCCHHHHHHHHH
MAGPLIGDMTSAESMAFDASAGATPCHGELLLAFDPTVFLGDRASEYLEKAESLFEAITS
HHCCHHCCCCCHHHHEECCCCCCCCCCCCEEEEECCEEEECCHHHHHHHHHHHHHHHHHH
QGARLPSQRRYAARARSDEAGVTVPRALYEDLLKLR
CCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: @UREI01.txt*(S)-Ureidoglycolate!; NAD(P)(+) [C]

Specific reaction: @UREI01.txt*(S)-Ureidoglycolate! + NAD(P)(+) = Oxalureate + NAD(P)H. [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]