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The map label for this gene is anr [H]

Identifier: 94313446

GI number: 94313446

Start: 1126289

End: 1127062

Strand: Direct

Name: anr [H]

Synonym: Rmet_4521

Alternate gene names: 94313446

Gene position: 1126289-1127062 (Clockwise)

Preceding gene: 94313443

Following gene: 94313448

Centisome position: 43.65

GC content: 62.66

Gene sequence:

>774_bases
ATGTATGAAGTGGTAGAGGGGTCAACCGTCGAAGCAGGAATGGATGGGGAATGCACCGGACATGCGCACGCGCCGAGCAC
GACGCGGCATTTCCAGGCGCGCTGCATGGATTGCGGCCTGCGCCGCCTCTGCATCGCCTCGTCTCTCGAACCGGAGGAGC
TTCCGCAACTGGAAGCCGTGGTCAGCCACTGGCGCATGGTGCATCGTGGCGAATACCTGTACCGCTCCGGCGACAAATTC
CAGAACCTCTACACCGTCCGGTCGGGATCGCTGAAGACCGTGGCCACCCACGCTGGCGGCCATGAGCACGTCACCGGCTT
CTTCCTGCCGGGAGAAACGGTCGGCCTTGGGGCGATTGGCGAAGGCGAGTATGACTGCGACGCGATTGCGCTCGAAGACA
GTGCCGTCTGCGTGCTGCCGTTCTCACCGCTCGAAGGACTGTGCCGCGACGTCAAGAGCGTGCAACAGCATTTCCACCGG
ATGCTGAGCCGCGAGATCCTGCGCGAGTCCAAGCAGATGATCCTGCTGTCGGGCATGACTTCGGAACAGCGTGTAGCGGC
ATTCCTGATCAACGTGTCGTGTCGCCTGCAGGAACGCGGCTATGCTTCGCGCGACTTCACGCTGCGCATGACCCGCGAGG
AAATCGGCAGCTACCTCGGCATCAAGCTCGAAACGGTCAGCCGCACGTTCTCCCGCTTCCAGCGCGAAGGCCTGATCCGC
GTGGATGGGAAGCGCATCGAACTGTTCGATATCGAGGCGCTCGCGGCCATCTGA

Upstream 100 bases:

>100_bases
TTTCCGATCACAAGGCATACTTCCGCGCAGATGGGGAGTTATTCAGATCAAAGAACCTTGATTTGGCGGTGAACGCCTGA
CGGCCCCAGGGGAGAGCATC

Downstream 100 bases:

>100_bases
GCCGCTGGCACCAGCGCCTGCTACTCACGGGCCTCCCGCCGCACCGCCTGCGGCGGCACGCCGAACCCCCGCAGGAACGC
CTCGCGCATATGGCGCCGGT

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MYEVVEGSTVEAGMDGECTGHAHAPSTTRHFQARCMDCGLRRLCIASSLEPEELPQLEAVVSHWRMVHRGEYLYRSGDKF
QNLYTVRSGSLKTVATHAGGHEHVTGFFLPGETVGLGAIGEGEYDCDAIALEDSAVCVLPFSPLEGLCRDVKSVQQHFHR
MLSREILRESKQMILLSGMTSEQRVAAFLINVSCRLQERGYASRDFTLRMTREEIGSYLGIKLETVSRTFSRFQREGLIR
VDGKRIELFDIEALAAI

Sequences:

>Translated_257_residues
MYEVVEGSTVEAGMDGECTGHAHAPSTTRHFQARCMDCGLRRLCIASSLEPEELPQLEAVVSHWRMVHRGEYLYRSGDKF
QNLYTVRSGSLKTVATHAGGHEHVTGFFLPGETVGLGAIGEGEYDCDAIALEDSAVCVLPFSPLEGLCRDVKSVQQHFHR
MLSREILRESKQMILLSGMTSEQRVAAFLINVSCRLQERGYASRDFTLRMTREEIGSYLGIKLETVSRTFSRFQREGLIR
VDGKRIELFDIEALAAI
>Mature_257_residues
MYEVVEGSTVEAGMDGECTGHAHAPSTTRHFQARCMDCGLRRLCIASSLEPEELPQLEAVVSHWRMVHRGEYLYRSGDKF
QNLYTVRSGSLKTVATHAGGHEHVTGFFLPGETVGLGAIGEGEYDCDAIALEDSAVCVLPFSPLEGLCRDVKSVQQHFHR
MLSREILRESKQMILLSGMTSEQRVAAFLINVSCRLQERGYASRDFTLRMTREEIGSYLGIKLETVSRTFSRFQREGLIR
VDGKRIELFDIEALAAI

Specific function: Transcriptional activator of anaerobic gene expression [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=223, Percent_Identity=39.9103139013453, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28749; Mature: 28749

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEVVEGSTVEAGMDGECTGHAHAPSTTRHFQARCMDCGLRRLCIASSLEPEELPQLEAV
CCEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VSHWRMVHRGEYLYRSGDKFQNLYTVRSGSLKTVATHAGGHEHVTGFFLPGETVGLGAIG
HHHHHHHHCCCCEECCCCHHHHEEEEECCCEEEEEECCCCCCCEEEEEECCCCEEECCCC
EGEYDCDAIALEDSAVCVLPFSPLEGLCRDVKSVQQHFHRMLSREILRESKQMILLSGMT
CCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SEQRVAAFLINVSCRLQERGYASRDFTLRMTREEIGSYLGIKLETVSRTFSRFQREGLIR
CHHHHEEEEEEEEEEECCCCCCCCCEEEEEEHHHHCHHHCEEHHHHHHHHHHHHHCCCEE
VDGKRIELFDIEALAAI
ECCCEEEEEEHHHHHCC
>Mature Secondary Structure
MYEVVEGSTVEAGMDGECTGHAHAPSTTRHFQARCMDCGLRRLCIASSLEPEELPQLEAV
CCEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VSHWRMVHRGEYLYRSGDKFQNLYTVRSGSLKTVATHAGGHEHVTGFFLPGETVGLGAIG
HHHHHHHHCCCCEECCCCHHHHEEEEECCCEEEEEECCCCCCCEEEEEECCCCEEECCCC
EGEYDCDAIALEDSAVCVLPFSPLEGLCRDVKSVQQHFHRMLSREILRESKQMILLSGMT
CCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
SEQRVAAFLINVSCRLQERGYASRDFTLRMTREEIGSYLGIKLETVSRTFSRFQREGLIR
CHHHHEEEEEEEEEEECCCCCCCCCEEEEEEHHHHCHHHCEEHHHHHHHHHHHHHCCCEE
VDGKRIELFDIEALAAI
ECCCEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787797; 1787798; 10984043 [H]