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The map label for this gene is rcsC [H]

Identifier: 94313181

GI number: 94313181

Start: 844245

End: 848501

Strand: Direct

Name: rcsC [H]

Synonym: Rmet_4255

Alternate gene names: 94313181

Gene position: 844245-848501 (Clockwise)

Preceding gene: 94313180

Following gene: 94313183

Centisome position: 32.72

GC content: 63.75

Gene sequence:

>4257_bases
GTGGCGCAGCAGCCCATTGCTACCACGGCGCAAACGATACGGGTTGGGGTAGTGCAGAACGACTGGCCGCCGTTTGCCAT
CGTGCAAGACGGACAGGTGAGCGGCATCGGTGTCGACTTCCTGCGCGCGGCGCTTGGCGACCGCCCCGTGCGCATTGTCA
CGACCACGTTTGCCAGTATGCCTGCCCTGCTGGCCGCCGCGTGCGCCAACCAGGTGGACGTGGTGCTGAACGTTGGCGAG
ACTGCCGAGCGCGCGCGTTGCCTGCGCTTTTCCGAGGCCTACTTCGATGCCACTGCCGCAATCGTCGGCCGCGCAGGGGC
AGCGGGGCAGGATGCCGTCGCATTGGAGCAGGCACGGATTGCGGTGGAGCCGGGCTCTTTCATGGACGAGCGGCTTCGCG
CACGGTTCCCGAATGCGCGGTTTGTGCCCGTGAAGGACGCTGAAGGCGGGTTGCGTGCCGTACGCGACAACCAGGCGGAT
TACTACCCCACGCGGCAGCCAGTGGCGGACTATTACTTGGGACGGCCCGAGTACAAAGGCCTGGCCGTTCAGGCAGGCTA
CCGGGAGCCCGGTGGCGGCCTGCATTTCGCGTTCAGTCCGGCCGCCGCCGCCCTACAGACCACCGTCAATCAGGGGCTCG
CCACGATGCCACAAGACGCGCGGCGCGCCATTATCGGTCGTTGGGTGACGCCTCCGATCGTAGCGTCGTCGCCTGCAGGA
GAGTTCTTTCTGACGCCGGAGGAGCGGGCGTTTCTGCAATCGCTGCCCGTGCTGAAGGTGGCATTCGACGCGGGGTCGGC
ACCCTATAGTTACGTCGACGACAGAGGACGACCCGGCGGCATGGCGGCTGACTACCTGTCATATCTGGGTCGCACGCTCG
GCGTACGGTTCCAGCGTGAGCGTGCCGCACCCTTTGCGCAGACCGTGGAAGCGCTGCGGCAAGGCAAGCTGGACCTGATG
GCCGTCGCCGTGGCCGAGGATCCAGCGCTGGCTGGCCTGCCGGTGACCCGGCCCTATGCCTCCTTCCCGATGGTCATCGT
GGGGCGCCAGCTGGATGTGGCGGTCGAAGGCCTCAACGACCTGACTGGCAAGCGTGTGGTCGTTTGTGAGGCGAGTGGTG
TGGAGGGCCTGCTCAGGGCAGCCGTCCCGCATCTGCAGTTGTCCGTCGTAAGTTCCGTGCATGCCGGCATGGAGGCGGTT
GCCAATGGGAAAGCCGATGCATATGTGGACGATCTGGCTACGGTGGACGTGGAGCTGCAACGTTATTTCGCGGGGACGCT
GCGCATCATAGGTTCCGGCAGACAAACGCTGGACATGGGCTTTGGCTTGTCCCCCGAGCTGGGAGCACGGCTGCTGCCGC
TCATTGACCGTGCCATGGAATACATGCCGCAAGTCGAGCGCCTCGCGATCCAGAGCCGTTACATCGCCGCCAGCTATGCT
CTGGAGCCCTCATGGCAGCAGGTCCTGCGACGCATCGCCCCATACCTGGTCGCCGTCATCGTTATTATCGGGATCCTGCT
GCGCTCGCAGTATCGATTGCGACGGGAGGCGTCCGCCAGGCGACTCGCCAAACAGCAGCTTCAGGCGCAACTGGATTTCC
AGCGCACGTTGATCGACGCCGTCCCGATTCCGATCACCGTCAAGGATGCCCAAGGGCGATACGTTGAAGTCAATGCCGCC
TTCCAGTCGCGGGCGGGGATGACTAGACAGCAGATGGTTGGTCACTTGCCCACAGAGCTGAATGTGCCGGGCAACCGCGC
AGCCGAAGCGTTGGAAGCGGGCTCCCGGCGAGCCCTGGAGACCCAACAGCTGCAGCAGTTTGCGGTGGACTACGTGGACG
CCGATGGCAAGCAACGCTATTACCTGTGCTGGGCGCAACCCATCAAGAGAGTCGGGCCGGAGTTCGCCGGGGTCATCTCG
GCCGCGGTGGATGTGACGGAGATTCGCAACGCCGAAGCCAAGGCCCAAGCTGCCGAGGCCATGCTTGTGGACGCGACTCG
CCATTTGCCCGCCACGGCTTTCCGAATGCGCGAGCGCGACGGTGTCTTTTCGTATGAGTGGGTGAGCGGCAATGCGCAGC
AACTGCTCGGTCGCTCATCAGAATCGTTGATTGGTCCGGCTAATCCGCTGCTGGGCATGGCCAACGTGGAGGACCGCATC
GCGGCGTTGGCCGCAGCCGAAGAGGCCAAAACCACGGGGCGGCCTTTGAGCGCGGACATGCGTCTTCTGATCCGTGGACA
AACACGCTGGATCCGCATCCATGCCGTGCCTAAGACAGAGCCGGATGGCGGCGTCCTGTGGCACGGCTACTATGTGGACC
TCACGGAAGAGCGCGAGCGTGCCAACGCACTGGCGCAGGCAAAGGATGCGGCCGAAGCGGCATCGCGAGCCAAGGACAGT
TTTCTGGCCATGATGAGCCATGAGATCCGCACGCCAATGAATGGCATTCTCGGCCTGATCGAACTGCTGCAAAGAACGCC
GCTGACGGCCGAGCAGCAGCGCATGGTCGCGTTGGCCGGCGAGTCTGGCCAGGCACTCGGACGGATACTGGACGACATTC
TGGACTACGCCAAACTCGAGGCCGGGCGGCTTGCCATCCTGCGAGCGCCGGTGGATCTTCGGGAACTCTTCGACGGCGTG
CTCGGCTCGCTGTTGCCGCAAGCTTTCCAGAAGGGCTTGCGTCTGAAGCAAAGGGTGAGCGCGGAGGTGGCGGCCATCGT
GCAGGCCGATGGCATCCGTCTGCGCCAGATTCTGTTCAATCTGCTAGGTAATGCCATCAAGTTTACCGATCACGGCAGCG
TGATGTTGCGCGCAACCATGGAGCCAGGTGCTACCGGGTTGCCAATGCTGGTCGTGGTCGTGGAAGACACTGGAATCGGT
ATTGCCAGGACGGATCTCGCTCGCCTGTTCGCCCCGTTCATGCAAAGCGAGCGCAGTACCGCACGCCGATTCGGTGGAAC
CGGGCTGGGGCTAACCATTGTCAGGACGCTGGCAGAGCTCATGGACGGCGAGATAACCCTGAAGAGCGAGGCGGGGGTGG
GTACGACGGCGGTACTCCGGGTGCCATGCGAAGTCGTCAGCCAGGGCTATGATTTGCCGAACCTCCGCGGCAGGGCGCTA
TCCGTTCTTGTCAGCGATGACAGCAGGCGTGCGGCCCTGATCGCCTACGGCGAGGCCGCCGGCATGCGCTGCGTCAGCCC
GGAGGATGAGACTCCGGACGATGGCATCGCAATTACCGATCGGATGGAGCGAGCCGGGCGAAAGGGCCAGTTTGCGATTC
ACCTGACCGATGAATTGCTGCCATTGGGTTACAGCCAGGATGAGTCTGGCGTGTCGCTCGGCAGCAATCCGTTGCGATGG
ACGGCTTTTGTGGGAGCACTGGAAGCGCTGCTCAAGGGCATTGCACCAGCCTCACCACAGGCCTCGCGGGCGGGAGAGGG
GAAAGCAGACGATCTGGTGCCCCAGGGCGCCAGGATCCTTGTCGTCGAGGACCATCCCATCAACCGGGAAGTTATCGGGC
AGCAATTGCGTCTGCTGGGCTACCGCAGCACGGTGTGCACCAACGGGCAGGAAGCGGTAACGGCGCTGCGGGCCGATACG
TATGATCTGGTGCTGACTGATTGCCACATGCCGGTCATGGACGGATTTGACTTGACTCGGTCGATCCGGGCGAGTGATCG
GCCGTCCGTCCGAGCGCTGCCCGTGGTGGGACTGACTGCAACAGTCGCCAGGGAAGAGCATGTCCTGTGCATGGAAGTGG
GCATGAACGCGTTCCTGGTGAAGCCGGCGACATTGGCATCGCTACAGCAGACGATCGAGACCGCATTGCAAGGAGGTCCG
GAGGCACCGTCGCCCAAGACGGAGGTTCGATCTCGGGAAGCATCACCGGCCCGTCGGACGCCCGAATCCGGCGGATTCCG
TCCGGAATGCATCGATACCGTCGGGCTGCGGTCCCAACTGGAGCCCATGTTGGCGGAGCGCGACGTGCGCCAGATCTTCT
TGCGATCCCTGGAACAAGACCGCGACGCCTTGCGTGCGCAGCTGGCGGCGCCGACGCCCGCAGGACTGGGCAAGTGGTGT
CATCGTGCCGGTGGCGCGATTTCGGTGATGGAGCAGCCATACCTGCACGAGTTGCTCGATCGGCTGGATGGTCTGCTGGA
GACCGGCTCCCCGGCTCAAATCCAGTCGGCGGGCGCTTCGCTGTCGGCGATGTATGACTACCTGATCGATTGGCTGGAGA
AGCTGGATGTTGCGTGA

Upstream 100 bases:

>100_bases
TGGTGTGCGCCTGTTGACGAGGCGGATTCGGTGGATCGACCTGCTCGGTCTGCTACGGTGCGTTGGCTTCTTGCTGTTGA
TGTCCATCTGGCATGACGCA

Downstream 100 bases:

>100_bases
CCGGCCTGCCAGGAAGATCGGGCGAGCGCCAGCCGAGACCGGCCCCGAATGCAAGGCCATCGGAATAGCCGGGCGATGTC
AGGCGATTGACGGCATCTTC

Product: PAS/PAC sensor, hybrid histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 1418; Mature: 1417

Protein sequence:

>1418_residues
MAQQPIATTAQTIRVGVVQNDWPPFAIVQDGQVSGIGVDFLRAALGDRPVRIVTTTFASMPALLAAACANQVDVVLNVGE
TAERARCLRFSEAYFDATAAIVGRAGAAGQDAVALEQARIAVEPGSFMDERLRARFPNARFVPVKDAEGGLRAVRDNQAD
YYPTRQPVADYYLGRPEYKGLAVQAGYREPGGGLHFAFSPAAAALQTTVNQGLATMPQDARRAIIGRWVTPPIVASSPAG
EFFLTPEERAFLQSLPVLKVAFDAGSAPYSYVDDRGRPGGMAADYLSYLGRTLGVRFQRERAAPFAQTVEALRQGKLDLM
AVAVAEDPALAGLPVTRPYASFPMVIVGRQLDVAVEGLNDLTGKRVVVCEASGVEGLLRAAVPHLQLSVVSSVHAGMEAV
ANGKADAYVDDLATVDVELQRYFAGTLRIIGSGRQTLDMGFGLSPELGARLLPLIDRAMEYMPQVERLAIQSRYIAASYA
LEPSWQQVLRRIAPYLVAVIVIIGILLRSQYRLRREASARRLAKQQLQAQLDFQRTLIDAVPIPITVKDAQGRYVEVNAA
FQSRAGMTRQQMVGHLPTELNVPGNRAAEALEAGSRRALETQQLQQFAVDYVDADGKQRYYLCWAQPIKRVGPEFAGVIS
AAVDVTEIRNAEAKAQAAEAMLVDATRHLPATAFRMRERDGVFSYEWVSGNAQQLLGRSSESLIGPANPLLGMANVEDRI
AALAAAEEAKTTGRPLSADMRLLIRGQTRWIRIHAVPKTEPDGGVLWHGYYVDLTEERERANALAQAKDAAEAASRAKDS
FLAMMSHEIRTPMNGILGLIELLQRTPLTAEQQRMVALAGESGQALGRILDDILDYAKLEAGRLAILRAPVDLRELFDGV
LGSLLPQAFQKGLRLKQRVSAEVAAIVQADGIRLRQILFNLLGNAIKFTDHGSVMLRATMEPGATGLPMLVVVVEDTGIG
IARTDLARLFAPFMQSERSTARRFGGTGLGLTIVRTLAELMDGEITLKSEAGVGTTAVLRVPCEVVSQGYDLPNLRGRAL
SVLVSDDSRRAALIAYGEAAGMRCVSPEDETPDDGIAITDRMERAGRKGQFAIHLTDELLPLGYSQDESGVSLGSNPLRW
TAFVGALEALLKGIAPASPQASRAGEGKADDLVPQGARILVVEDHPINREVIGQQLRLLGYRSTVCTNGQEAVTALRADT
YDLVLTDCHMPVMDGFDLTRSIRASDRPSVRALPVVGLTATVAREEHVLCMEVGMNAFLVKPATLASLQQTIETALQGGP
EAPSPKTEVRSREASPARRTPESGGFRPECIDTVGLRSQLEPMLAERDVRQIFLRSLEQDRDALRAQLAAPTPAGLGKWC
HRAGGAISVMEQPYLHELLDRLDGLLETGSPAQIQSAGASLSAMYDYLIDWLEKLDVA

Sequences:

>Translated_1418_residues
MAQQPIATTAQTIRVGVVQNDWPPFAIVQDGQVSGIGVDFLRAALGDRPVRIVTTTFASMPALLAAACANQVDVVLNVGE
TAERARCLRFSEAYFDATAAIVGRAGAAGQDAVALEQARIAVEPGSFMDERLRARFPNARFVPVKDAEGGLRAVRDNQAD
YYPTRQPVADYYLGRPEYKGLAVQAGYREPGGGLHFAFSPAAAALQTTVNQGLATMPQDARRAIIGRWVTPPIVASSPAG
EFFLTPEERAFLQSLPVLKVAFDAGSAPYSYVDDRGRPGGMAADYLSYLGRTLGVRFQRERAAPFAQTVEALRQGKLDLM
AVAVAEDPALAGLPVTRPYASFPMVIVGRQLDVAVEGLNDLTGKRVVVCEASGVEGLLRAAVPHLQLSVVSSVHAGMEAV
ANGKADAYVDDLATVDVELQRYFAGTLRIIGSGRQTLDMGFGLSPELGARLLPLIDRAMEYMPQVERLAIQSRYIAASYA
LEPSWQQVLRRIAPYLVAVIVIIGILLRSQYRLRREASARRLAKQQLQAQLDFQRTLIDAVPIPITVKDAQGRYVEVNAA
FQSRAGMTRQQMVGHLPTELNVPGNRAAEALEAGSRRALETQQLQQFAVDYVDADGKQRYYLCWAQPIKRVGPEFAGVIS
AAVDVTEIRNAEAKAQAAEAMLVDATRHLPATAFRMRERDGVFSYEWVSGNAQQLLGRSSESLIGPANPLLGMANVEDRI
AALAAAEEAKTTGRPLSADMRLLIRGQTRWIRIHAVPKTEPDGGVLWHGYYVDLTEERERANALAQAKDAAEAASRAKDS
FLAMMSHEIRTPMNGILGLIELLQRTPLTAEQQRMVALAGESGQALGRILDDILDYAKLEAGRLAILRAPVDLRELFDGV
LGSLLPQAFQKGLRLKQRVSAEVAAIVQADGIRLRQILFNLLGNAIKFTDHGSVMLRATMEPGATGLPMLVVVVEDTGIG
IARTDLARLFAPFMQSERSTARRFGGTGLGLTIVRTLAELMDGEITLKSEAGVGTTAVLRVPCEVVSQGYDLPNLRGRAL
SVLVSDDSRRAALIAYGEAAGMRCVSPEDETPDDGIAITDRMERAGRKGQFAIHLTDELLPLGYSQDESGVSLGSNPLRW
TAFVGALEALLKGIAPASPQASRAGEGKADDLVPQGARILVVEDHPINREVIGQQLRLLGYRSTVCTNGQEAVTALRADT
YDLVLTDCHMPVMDGFDLTRSIRASDRPSVRALPVVGLTATVAREEHVLCMEVGMNAFLVKPATLASLQQTIETALQGGP
EAPSPKTEVRSREASPARRTPESGGFRPECIDTVGLRSQLEPMLAERDVRQIFLRSLEQDRDALRAQLAAPTPAGLGKWC
HRAGGAISVMEQPYLHELLDRLDGLLETGSPAQIQSAGASLSAMYDYLIDWLEKLDVA
>Mature_1417_residues
AQQPIATTAQTIRVGVVQNDWPPFAIVQDGQVSGIGVDFLRAALGDRPVRIVTTTFASMPALLAAACANQVDVVLNVGET
AERARCLRFSEAYFDATAAIVGRAGAAGQDAVALEQARIAVEPGSFMDERLRARFPNARFVPVKDAEGGLRAVRDNQADY
YPTRQPVADYYLGRPEYKGLAVQAGYREPGGGLHFAFSPAAAALQTTVNQGLATMPQDARRAIIGRWVTPPIVASSPAGE
FFLTPEERAFLQSLPVLKVAFDAGSAPYSYVDDRGRPGGMAADYLSYLGRTLGVRFQRERAAPFAQTVEALRQGKLDLMA
VAVAEDPALAGLPVTRPYASFPMVIVGRQLDVAVEGLNDLTGKRVVVCEASGVEGLLRAAVPHLQLSVVSSVHAGMEAVA
NGKADAYVDDLATVDVELQRYFAGTLRIIGSGRQTLDMGFGLSPELGARLLPLIDRAMEYMPQVERLAIQSRYIAASYAL
EPSWQQVLRRIAPYLVAVIVIIGILLRSQYRLRREASARRLAKQQLQAQLDFQRTLIDAVPIPITVKDAQGRYVEVNAAF
QSRAGMTRQQMVGHLPTELNVPGNRAAEALEAGSRRALETQQLQQFAVDYVDADGKQRYYLCWAQPIKRVGPEFAGVISA
AVDVTEIRNAEAKAQAAEAMLVDATRHLPATAFRMRERDGVFSYEWVSGNAQQLLGRSSESLIGPANPLLGMANVEDRIA
ALAAAEEAKTTGRPLSADMRLLIRGQTRWIRIHAVPKTEPDGGVLWHGYYVDLTEERERANALAQAKDAAEAASRAKDSF
LAMMSHEIRTPMNGILGLIELLQRTPLTAEQQRMVALAGESGQALGRILDDILDYAKLEAGRLAILRAPVDLRELFDGVL
GSLLPQAFQKGLRLKQRVSAEVAAIVQADGIRLRQILFNLLGNAIKFTDHGSVMLRATMEPGATGLPMLVVVVEDTGIGI
ARTDLARLFAPFMQSERSTARRFGGTGLGLTIVRTLAELMDGEITLKSEAGVGTTAVLRVPCEVVSQGYDLPNLRGRALS
VLVSDDSRRAALIAYGEAAGMRCVSPEDETPDDGIAITDRMERAGRKGQFAIHLTDELLPLGYSQDESGVSLGSNPLRWT
AFVGALEALLKGIAPASPQASRAGEGKADDLVPQGARILVVEDHPINREVIGQQLRLLGYRSTVCTNGQEAVTALRADTY
DLVLTDCHMPVMDGFDLTRSIRASDRPSVRALPVVGLTATVAREEHVLCMEVGMNAFLVKPATLASLQQTIETALQGGPE
APSPKTEVRSREASPARRTPESGGFRPECIDTVGLRSQLEPMLAERDVRQIFLRSLEQDRDALRAQLAAPTPAGLGKWCH
RAGGAISVMEQPYLHELLDRLDGLLETGSPAQIQSAGASLSAMYDYLIDWLEKLDVA

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=522, Percent_Identity=34.4827586206897, Blast_Score=258, Evalue=2e-69,
Organism=Escherichia coli, GI1789149, Length=656, Percent_Identity=29.1158536585366, Blast_Score=211, Evalue=2e-55,
Organism=Escherichia coli, GI48994928, Length=292, Percent_Identity=37.6712328767123, Blast_Score=173, Evalue=9e-44,
Organism=Escherichia coli, GI1788713, Length=310, Percent_Identity=32.5806451612903, Blast_Score=153, Evalue=7e-38,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=40, Blast_Score=153, Evalue=8e-38,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=28.2786885245902, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1786600, Length=369, Percent_Identity=24.390243902439, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=30.6666666666667, Blast_Score=84, Evalue=7e-17,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=28.3842794759825, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=248, Percent_Identity=29.8387096774194, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=31.404958677686, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=238, Percent_Identity=28.1512605042017, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=22.7450980392157, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=27.1929824561404, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=28.5106382978723, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=33.8983050847458, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=350, Percent_Identity=29.7142857142857, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 153346; Mature: 153215

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQQPIATTAQTIRVGVVQNDWPPFAIVQDGQVSGIGVDFLRAALGDRPVRIVTTTFASM
CCCCCCCHHHHHEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEHHHHH
PALLAAACANQVDVVLNVGETAERARCLRFSEAYFDATAAIVGRAGAAGQDAVALEQARI
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEE
AVEPGSFMDERLRARFPNARFVPVKDAEGGLRAVRDNQADYYPTRQPVADYYLGRPEYKG
EECCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCCCCC
LAVQAGYREPGGGLHFAFSPAAAALQTTVNQGLATMPQDARRAIIGRWVTPPIVASSPAG
EEEECCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEECCCCC
EFFLTPEERAFLQSLPVLKVAFDAGSAPYSYVDDRGRPGGMAADYLSYLGRTLGVRFQRE
CEEECCHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCEEEHH
RAAPFAQTVEALRQGKLDLMAVAVAEDPALAGLPVTRPYASFPMVIVGRQLDVAVEGLND
HCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCHHC
LTGKRVVVCEASGVEGLLRAAVPHLQLSVVSSVHAGMEAVANGKADAYVDDLATVDVELQ
CCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RYFAGTLRIIGSGRQTLDMGFGLSPELGARLLPLIDRAMEYMPQVERLAIQSRYIAASYA
HHHHHHHHEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LEPSWQQVLRRIAPYLVAVIVIIGILLRSQYRLRREASARRLAKQQLQAQLDFQRTLIDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIPITVKDAQGRYVEVNAAFQSRAGMTRQQMVGHLPTELNVPGNRAAEALEAGSRRALE
CCCCEEEECCCCCEEEEECHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHH
TQQLQQFAVDYVDADGKQRYYLCWAQPIKRVGPEFAGVISAAVDVTEIRNAEAKAQAAEA
HHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MLVDATRHLPATAFRMRERDGVFSYEWVSGNAQQLLGRSSESLIGPANPLLGMANVEDRI
HHHHHHHCCCHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
AALAAAEEAKTTGRPLSADMRLLIRGQTRWIRIHAVPKTEPDGGVLWHGYYVDLTEERER
HHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCEEEEEEEEEECHHHHH
ANALAQAKDAAEAASRAKDSFLAMMSHEIRTPMNGILGLIELLQRTPLTAEQQRMVALAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHEEEEEC
ESGQALGRILDDILDYAKLEAGRLAILRAPVDLRELFDGVLGSLLPQAFQKGLRLKQRVS
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEVAAIVQADGIRLRQILFNLLGNAIKFTDHGSVMLRATMEPGATGLPMLVVVVEDTGIG
HHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCC
IARTDLARLFAPFMQSERSTARRFGGTGLGLTIVRTLAELMDGEITLKSEAGVGTTAVLR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEE
VPCEVVSQGYDLPNLRGRALSVLVSDDSRRAALIAYGEAAGMRCVSPEDETPDDGIAITD
CCHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCCCCEEEHH
RMERAGRKGQFAIHLTDELLPLGYSQDESGVSLGSNPLRWTAFVGALEALLKGIAPASPQ
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
ASRAGEGKADDLVPQGARILVVEDHPINREVIGQQLRLLGYRSTVCTNGQEAVTALRADT
CCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
YDLVLTDCHMPVMDGFDLTRSIRASDRPSVRALPVVGLTATVAREEHVLCMEVGMNAFLV
EEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCEEEEECCCCEEEE
KPATLASLQQTIETALQGGPEAPSPKTEVRSREASPARRTPESGGFRPECIDTVGLRSQL
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EPMLAERDVRQIFLRSLEQDRDALRAQLAAPTPAGLGKWCHRAGGAISVMEQPYLHELLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCHHHHHHHH
RLDGLLETGSPAQIQSAGASLSAMYDYLIDWLEKLDVA
HHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQQPIATTAQTIRVGVVQNDWPPFAIVQDGQVSGIGVDFLRAALGDRPVRIVTTTFASM
CCCCCCHHHHHEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEHHHHH
PALLAAACANQVDVVLNVGETAERARCLRFSEAYFDATAAIVGRAGAAGQDAVALEQARI
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHEE
AVEPGSFMDERLRARFPNARFVPVKDAEGGLRAVRDNQADYYPTRQPVADYYLGRPEYKG
EECCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCCCCC
LAVQAGYREPGGGLHFAFSPAAAALQTTVNQGLATMPQDARRAIIGRWVTPPIVASSPAG
EEEECCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEECCCCC
EFFLTPEERAFLQSLPVLKVAFDAGSAPYSYVDDRGRPGGMAADYLSYLGRTLGVRFQRE
CEEECCHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCEEEHH
RAAPFAQTVEALRQGKLDLMAVAVAEDPALAGLPVTRPYASFPMVIVGRQLDVAVEGLND
HCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCHHC
LTGKRVVVCEASGVEGLLRAAVPHLQLSVVSSVHAGMEAVANGKADAYVDDLATVDVELQ
CCCCEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RYFAGTLRIIGSGRQTLDMGFGLSPELGARLLPLIDRAMEYMPQVERLAIQSRYIAASYA
HHHHHHHHEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LEPSWQQVLRRIAPYLVAVIVIIGILLRSQYRLRREASARRLAKQQLQAQLDFQRTLIDA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIPITVKDAQGRYVEVNAAFQSRAGMTRQQMVGHLPTELNVPGNRAAEALEAGSRRALE
CCCCEEEECCCCCEEEEECHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHH
TQQLQQFAVDYVDADGKQRYYLCWAQPIKRVGPEFAGVISAAVDVTEIRNAEAKAQAAEA
HHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MLVDATRHLPATAFRMRERDGVFSYEWVSGNAQQLLGRSSESLIGPANPLLGMANVEDRI
HHHHHHHCCCHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
AALAAAEEAKTTGRPLSADMRLLIRGQTRWIRIHAVPKTEPDGGVLWHGYYVDLTEERER
HHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCEEEEEEEEEECHHHHH
ANALAQAKDAAEAASRAKDSFLAMMSHEIRTPMNGILGLIELLQRTPLTAEQQRMVALAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHEEEEEC
ESGQALGRILDDILDYAKLEAGRLAILRAPVDLRELFDGVLGSLLPQAFQKGLRLKQRVS
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEVAAIVQADGIRLRQILFNLLGNAIKFTDHGSVMLRATMEPGATGLPMLVVVVEDTGIG
HHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEECCCCC
IARTDLARLFAPFMQSERSTARRFGGTGLGLTIVRTLAELMDGEITLKSEAGVGTTAVLR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEE
VPCEVVSQGYDLPNLRGRALSVLVSDDSRRAALIAYGEAAGMRCVSPEDETPDDGIAITD
CCHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCCCCEEEHH
RMERAGRKGQFAIHLTDELLPLGYSQDESGVSLGSNPLRWTAFVGALEALLKGIAPASPQ
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
ASRAGEGKADDLVPQGARILVVEDHPINREVIGQQLRLLGYRSTVCTNGQEAVTALRADT
CCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
YDLVLTDCHMPVMDGFDLTRSIRASDRPSVRALPVVGLTATVAREEHVLCMEVGMNAFLV
EEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCEEEEECCCCEEEE
KPATLASLQQTIETALQGGPEAPSPKTEVRSREASPARRTPESGGFRPECIDTVGLRSQL
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EPMLAERDVRQIFLRSLEQDRDALRAQLAAPTPAGLGKWCHRAGGAISVMEQPYLHELLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCHHHHHHHH
RLDGLLETGSPAQIQSAGASLSAMYDYLIDWLEKLDVA
HHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]