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The map label for this gene is pdhB [H]

Identifier: 94313060

GI number: 94313060

Start: 707434

End: 708414

Strand: Reverse

Name: pdhB [H]

Synonym: Rmet_4133

Alternate gene names: 94313060

Gene position: 708414-707434 (Counterclockwise)

Preceding gene: 94313061

Following gene: 94313059

Centisome position: 27.46

GC content: 69.72

Gene sequence:

>981_bases
ATGGCTGAACTGCATATGGTGGAAGCCGTCAACCTGGCCCTGGCCCATGCCCTCGCCAACGATCCCGACGTGGTGCTGCT
GGGCGAGGACATCGGCGTGAACGGCGGCGTATTCCGCTCGACTGTGGGGCTGCAGTCGCGCTTCGGCGAGGCCCGCGTCA
TCGACACGCCGCTGGCCGAAGGCGCCATCGTCGGCGCGGCCATCGGCATGGCGGCGATGGGGCTCAAGCCCGTCGCGGAG
ATCCAGTTCGCCGGCTTCATCTATCCGGCGATCGACAACATCCTGAATCACGCGGGTCATATGCGGCACCGCACACGCGG
CCGGATCACGTGCCCGATGGTTGTGCGCGCGCCGAGCGGCGCGGGCATCCACGCGCCCGAACACCATTCCGAAAGCCCGG
AGGCCCTGTTCGCGCAGATGCCGGGCATCCGCGTGGTCATGCCTTCATCGCCGGCGCGCGCCTACGGGCTGCTGCTCGCG
GCGATTCGCGACCCGGACCCGGTGATCTTCCTGGAGCCCACCCGCCTGTACCGGCTGTTCCGGCAGGAGGTCGCCGACGA
CGGCCAGGCGCTGCCCCTCGACGCCTGCTTCACGCTGCGCGAGGGCACGGACCTCACGCTGGTGAGCTGGGGCGCGATGT
TGCGGGAAACGCTGGCCGCGGCCGATGTGCTGGCCGACGACGGCGTTTCCGCGGCAGTGATCGACGTGGCCACGCTCAAG
CCGCTGGACATGGAGACCATCCTGGAGTCGGTTGCGCAGAGCGGCCGATGCGTGATCGTGCATGAAGCACCGCGCACCGC
CGGCCTGGGCGCAGAGATTGCCGCCAACCTGGCCGACGCGGGACTCTATTCGCTGAGCGCCCCGGTGCAGCGCGTGACGG
CGCCTGACACGGTGGTGCCGCTGGCGCGACTCGAACACAGCTACATGCCGTCGGTGGCGCGGATTGTCGACGCGGCGCGA
CGCGCGCTGGAAGCAGCCTAG

Upstream 100 bases:

>100_bases
GATTGCCTGTATGAAACGCTGCCCGACGCCATGGCCGAACAACTCGACACCGCGCGGCAATACGACGCCTCTGGCAAGAC
CGATACCTCGGGAGCCCATC

Downstream 100 bases:

>100_bases
CCAAGGAGAGATAGCGATGCGGATCTTCAAGCTGCCCGACCTGGGCGAAGGCCTGCAGGAAGCGGAAATCGTCAACTGGC
ATGTGAAGCCCGGGGACACC

Product: putative puryvate dehydrogenase E1 component subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAELHMVEAVNLALAHALANDPDVVLLGEDIGVNGGVFRSTVGLQSRFGEARVIDTPLAEGAIVGAAIGMAAMGLKPVAE
IQFAGFIYPAIDNILNHAGHMRHRTRGRITCPMVVRAPSGAGIHAPEHHSESPEALFAQMPGIRVVMPSSPARAYGLLLA
AIRDPDPVIFLEPTRLYRLFRQEVADDGQALPLDACFTLREGTDLTLVSWGAMLRETLAAADVLADDGVSAAVIDVATLK
PLDMETILESVAQSGRCVIVHEAPRTAGLGAEIAANLADAGLYSLSAPVQRVTAPDTVVPLARLEHSYMPSVARIVDAAR
RALEAA

Sequences:

>Translated_326_residues
MAELHMVEAVNLALAHALANDPDVVLLGEDIGVNGGVFRSTVGLQSRFGEARVIDTPLAEGAIVGAAIGMAAMGLKPVAE
IQFAGFIYPAIDNILNHAGHMRHRTRGRITCPMVVRAPSGAGIHAPEHHSESPEALFAQMPGIRVVMPSSPARAYGLLLA
AIRDPDPVIFLEPTRLYRLFRQEVADDGQALPLDACFTLREGTDLTLVSWGAMLRETLAAADVLADDGVSAAVIDVATLK
PLDMETILESVAQSGRCVIVHEAPRTAGLGAEIAANLADAGLYSLSAPVQRVTAPDTVVPLARLEHSYMPSVARIVDAAR
RALEAA
>Mature_325_residues
AELHMVEAVNLALAHALANDPDVVLLGEDIGVNGGVFRSTVGLQSRFGEARVIDTPLAEGAIVGAAIGMAAMGLKPVAEI
QFAGFIYPAIDNILNHAGHMRHRTRGRITCPMVVRAPSGAGIHAPEHHSESPEALFAQMPGIRVVMPSSPARAYGLLLAA
IRDPDPVIFLEPTRLYRLFRQEVADDGQALPLDACFTLREGTDLTLVSWGAMLRETLAAADVLADDGVSAAVIDVATLKP
LDMETILESVAQSGRCVIVHEAPRTAGLGAEIAANLADAGLYSLSAPVQRVTAPDTVVPLARLEHSYMPSVARIVDAARR
ALEAA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=324, Percent_Identity=41.9753086419753, Blast_Score=264, Evalue=7e-71,
Organism=Homo sapiens, GI34101272, Length=324, Percent_Identity=41.9753086419753, Blast_Score=264, Evalue=7e-71,
Organism=Homo sapiens, GI156564403, Length=322, Percent_Identity=34.472049689441, Blast_Score=188, Evalue=5e-48,
Organism=Homo sapiens, GI291084858, Length=321, Percent_Identity=33.0218068535826, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17506935, Length=326, Percent_Identity=41.4110429447853, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17538422, Length=324, Percent_Identity=36.4197530864198, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6319698, Length=322, Percent_Identity=38.1987577639752, Blast_Score=212, Evalue=6e-56,
Organism=Drosophila melanogaster, GI160714828, Length=317, Percent_Identity=41.6403785488959, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI160714832, Length=317, Percent_Identity=41.6403785488959, Blast_Score=247, Evalue=6e-66,
Organism=Drosophila melanogaster, GI21358145, Length=326, Percent_Identity=36.5030674846626, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24650940, Length=326, Percent_Identity=36.5030674846626, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24650943, Length=91, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24650945, Length=91, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 34389; Mature: 34258

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELHMVEAVNLALAHALANDPDVVLLGEDIGVNGGVFRSTVGLQSRFGEARVIDTPLAE
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
GAIVGAAIGMAAMGLKPVAEIQFAGFIYPAIDNILNHAGHMRHRTRGRITCPMVVRAPSG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCC
AGIHAPEHHSESPEALFAQMPGIRVVMPSSPARAYGLLLAAIRDPDPVIFLEPTRLYRLF
CCCCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHEECCCCCEEEECHHHHHHHH
RQEVADDGQALPLDACFTLREGTDLTLVSWGAMLRETLAAADVLADDGVSAAVIDVATLK
HHHHCCCCCCCCHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCC
PLDMETILESVAQSGRCVIVHEAPRTAGLGAEIAANLADAGLYSLSAPVQRVTAPDTVVP
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHHCCCHHHCCCCCHHHH
LARLEHSYMPSVARIVDAARRALEAA
HHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AELHMVEAVNLALAHALANDPDVVLLGEDIGVNGGVFRSTVGLQSRFGEARVIDTPLAE
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
GAIVGAAIGMAAMGLKPVAEIQFAGFIYPAIDNILNHAGHMRHRTRGRITCPMVVRAPSG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEEEECCCC
AGIHAPEHHSESPEALFAQMPGIRVVMPSSPARAYGLLLAAIRDPDPVIFLEPTRLYRLF
CCCCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHEECCCCCEEEECHHHHHHHH
RQEVADDGQALPLDACFTLREGTDLTLVSWGAMLRETLAAADVLADDGVSAAVIDVATLK
HHHHCCCCCCCCHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCC
PLDMETILESVAQSGRCVIVHEAPRTAGLGAEIAANLADAGLYSLSAPVQRVTAPDTVVP
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHHCCCHHHCCCCCHHHH
LARLEHSYMPSVARIVDAARRALEAA
HHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2200674; 2253629 [H]