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The map label for this gene is tctD [H]

Identifier: 94312862

GI number: 94312862

Start: 491819

End: 492490

Strand: Direct

Name: tctD [H]

Synonym: Rmet_3934

Alternate gene names: 94312862

Gene position: 491819-492490 (Clockwise)

Preceding gene: 94312853

Following gene: 94312863

Centisome position: 19.06

GC content: 64.43

Gene sequence:

>672_bases
GTGCGCCTGCTACTCGTTGAAGATCACCCGGATCTGGCTGCGCTGGTCATCAAGTCCCTCGGGGACAGCGGCTTCGTCAT
TGACCACGCCGTGGACGGCGAGGCCGCGCTGCTGATGATCGCCACCGCTTCGTACGATCTGATCCTTCTGGACCTCTCGC
TGGGGAAGGTCGACGGGCTGGACGTTCTTCGCTCGATCCGGACGCAGGGTGTCACGACACCGGTGTTGATCCTGACGGCC
CGCAGCGAGATCGCCGATCGCATCCTGGGCCTCGACCTCGGGGCCGACGACTATATCGCCAAGCCCTTCGACCTTGGCGA
ACTCGAGGCACGCATCAAGGCGCAGCTTCGCCGCCGCCAGGGTGGCCAGCCGGTGACCACCTACGGCGGCCTGTCATTCG
ATTCGGTGGAGAGATCGTTCTACTGCGAGGGCACGGCGTTGACGCTGAGCCGGCGCGAACTGGCGGTGCTGGAAGCGCTG
TTCCTGAGGGCCGGCCGCGTCGCCACCCGGGACGTGCTGTTCCAGTGCGTGTTCTCGATCGACGACGAGGTCAATCCCGA
AACTATCGAACTGTATGTGTCGCGGGTCAGGAAGAAGCTGAAGCCGAGCGGTCTGGTCATCACCGCCGTGCGAGGCGTCG
GCTATCTGCTGGAACAGCGTCAGGATGGCTAG

Upstream 100 bases:

>100_bases
CGCCGGATGGCTATCATTTCTGTCTTGCCATGCTAAGTCGGTCGGCTGTCGCCAAGCTGTCGAACGCCTGCCAGATTGTT
TAACGTAAACCCTGCCAAAA

Downstream 100 bases:

>100_bases
GCAGCCTTCGGCGACGAGCTTGCGCCGGACCCTGCTCTGGCGCCTGGCGCTCGCGTTGCTGACCGTCGGCATCGTCTCGG
CTTTCGCCTCATATCGCACC

Product: DNA-binding response regulator in two-component regulatory system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRLLLVEDHPDLAALVIKSLGDSGFVIDHAVDGEAALLMIATASYDLILLDLSLGKVDGLDVLRSIRTQGVTTPVLILTA
RSEIADRILGLDLGADDYIAKPFDLGELEARIKAQLRRRQGGQPVTTYGGLSFDSVERSFYCEGTALTLSRRELAVLEAL
FLRAGRVATRDVLFQCVFSIDDEVNPETIELYVSRVRKKLKPSGLVITAVRGVGYLLEQRQDG

Sequences:

>Translated_223_residues
MRLLLVEDHPDLAALVIKSLGDSGFVIDHAVDGEAALLMIATASYDLILLDLSLGKVDGLDVLRSIRTQGVTTPVLILTA
RSEIADRILGLDLGADDYIAKPFDLGELEARIKAQLRRRQGGQPVTTYGGLSFDSVERSFYCEGTALTLSRRELAVLEAL
FLRAGRVATRDVLFQCVFSIDDEVNPETIELYVSRVRKKLKPSGLVITAVRGVGYLLEQRQDG
>Mature_223_residues
MRLLLVEDHPDLAALVIKSLGDSGFVIDHAVDGEAALLMIATASYDLILLDLSLGKVDGLDVLRSIRTQGVTTPVLILTA
RSEIADRILGLDLGADDYIAKPFDLGELEARIKAQLRRRQGGQPVTTYGGLSFDSVERSFYCEGTALTLSRRELAVLEAL
FLRAGRVATRDVLFQCVFSIDDEVNPETIELYVSRVRKKLKPSGLVITAVRGVGYLLEQRQDG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=38.4615384615385, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=37.1559633027523, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=38.0733944954128, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=36.6071428571429, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=33.1838565022422, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=34.2222222222222, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.5991189427313, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=32.579185520362, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=32.1266968325792, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=34.5291479820628, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.6491228070175, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.4159292035398, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=112, Percent_Identity=30.3571428571429, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24402; Mature: 24402

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLVEDHPDLAALVIKSLGDSGFVIDHAVDGEAALLMIATASYDLILLDLSLGKVDGL
CEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCEEEEEEECCCCCCHH
DVLRSIRTQGVTTPVLILTARSEIADRILGLDLGADDYIAKPFDLGELEARIKAQLRRRQ
HHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GGQPVTTYGGLSFDSVERSFYCEGTALTLSRRELAVLEALFLRAGRVATRDVLFQCVFSI
CCCCEEEECCCCHHHHCCEEEECCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
DDEVNPETIELYVSRVRKKLKPSGLVITAVRGVGYLLEQRQDG
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLLLVEDHPDLAALVIKSLGDSGFVIDHAVDGEAALLMIATASYDLILLDLSLGKVDGL
CEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCEEEEEEECCCCCCHH
DVLRSIRTQGVTTPVLILTARSEIADRILGLDLGADDYIAKPFDLGELEARIKAQLRRRQ
HHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GGQPVTTYGGLSFDSVERSFYCEGTALTLSRRELAVLEALFLRAGRVATRDVLFQCVFSI
CCCCEEEECCCCHHHHCCEEEECCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
DDEVNPETIELYVSRVRKKLKPSGLVITAVRGVGYLLEQRQDG
CCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]