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The map label for this gene is qseC [H]

Identifier: 94312863

GI number: 94312863

Start: 492483

End: 493910

Strand: Direct

Name: qseC [H]

Synonym: Rmet_3935

Alternate gene names: 94312863

Gene position: 492483-493910 (Clockwise)

Preceding gene: 94312862

Following gene: 94312864

Centisome position: 19.09

GC content: 65.76

Gene sequence:

>1428_bases
ATGGCTAGGCAGCCTTCGGCGACGAGCTTGCGCCGGACCCTGCTCTGGCGCCTGGCGCTCGCGTTGCTGACCGTCGGCAT
CGTCTCGGCTTTCGCCTCATATCGCACCGCGCTGAAGGAAGCCAATCAGGCGCACGACCGAACGCTGCTGGCCTCTACGC
GCTCGATTGCCGAGCGTATCCACGTGACTAACGGCCGGGTGACCGTCAACGTCCCCTATGGCGCGCTGGATACGTTCCAG
ATCGATGCGCGCGGGCGGATTTTCTATCGCGTGCTGGATCCGGCAGGCCATTTCGTCTCCGGCGAGAAGGACTTCCCGGC
AATGCCGGCCAATGTGCCGCGCAGCGAGGACTATCCGGCGCTGGTCCATTTCTATGACGATGCCTATGCCGGAACGCCCC
TGCGCGTGGCGGCGCTGTGGCAGCCGGTGACCGAGGGCGGGCAGCAGGGCGTTGCGCTGGTGCAGGTGGGGGAATCGCTG
GAGATGCGGGATGACATGGCCAGACGGTTGCTGTTCACCATGCTCTGGCAACAGGCGGCGATGATCGGCGTCTCGATGAC
GTTGCTGGCATTGACGGTGGCCGCCACGCTGCGGCCGCTGAAGCGGTTGCAGGATCGCATTCAGGCCCGCCGGGCATCGG
ACCTCGCTCCGGTCGAGGGCGATGACCTGCCCAGGGAAATCCAGCCGCTGCTGCAAACGCTGAATCAGTACCTCGAACGT
CTGCGGGTCATCGTCGAAAACCAGAAGCGCTTTCTCGACGATGCCGCGCATCAGCTTCGGACATCGCTGACGCTGGTCAG
GGGCCATGTGGACCAGCGCATACGCGCTTCGGATCACGGCGGCGATCTCGCCGAGGTCAAGGCCGCCATCGACCGGACAG
TGCGGTTGACCAACCAGTTGCTGACGTTGGCGCGTACAGGGGATGGCGACGTCCTTGCGCCGGACGGTGACGCGATGCAG
CGCATCGAACTGGGCAACCTTTGCCGCGATATCTGCGCGGAGTGGTATCTCCATGCGCGGGAGCGGAGGCAGGATCTCAG
CGTGGGCGAATGTCCGGCTGGTGCATGGGTCGTTGGCAACGAGGCCATGCTACGAGAGATGCTGGCCAACCTCCTGCACA
ATGCCGTGAGCTACACGCCGGCTGGTGGGAGCATCTCCGTGACGGTGGAGCGGTCCGACAGCACGCTCTGCATCCTGGTG
GACGATAGCGGGCCCGGCATCCCTTCGGCGGATCGCGAACGCGTGTTCGAACGCTTCGTTCGCATCGCCGGCACGCTCGG
GGCGGGGAGCGGACTTGGTCTGGCGATCGTTCGGCAAATCTGCGAAGCGCATCAGGGTAGCGTGCAACTGGAGTCCGGCG
ACAAGGGCGGGCTACGCGTCAGGGTGACGCTGCCGGCGGCCCCCGCCGCACCGCCCGCTGTGGCCTGA

Upstream 100 bases:

>100_bases
ATCGAACTGTATGTGTCGCGGGTCAGGAAGAAGCTGAAGCCGAGCGGTCTGGTCATCACCGCCGTGCGAGGCGTCGGCTA
TCTGCTGGAACAGCGTCAGG

Downstream 100 bases:

>100_bases
CAGGCGCTGCAATCCAATCCGATTGGCCATTTGTAACTCCCCCCTGCAAGTCATCAGACGACGGCCTATAATCCCTGATT
CATTGATGCAACAACGATTG

Product: sensor protein in two-component regulatory system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MARQPSATSLRRTLLWRLALALLTVGIVSAFASYRTALKEANQAHDRTLLASTRSIAERIHVTNGRVTVNVPYGALDTFQ
IDARGRIFYRVLDPAGHFVSGEKDFPAMPANVPRSEDYPALVHFYDDAYAGTPLRVAALWQPVTEGGQQGVALVQVGESL
EMRDDMARRLLFTMLWQQAAMIGVSMTLLALTVAATLRPLKRLQDRIQARRASDLAPVEGDDLPREIQPLLQTLNQYLER
LRVIVENQKRFLDDAAHQLRTSLTLVRGHVDQRIRASDHGGDLAEVKAAIDRTVRLTNQLLTLARTGDGDVLAPDGDAMQ
RIELGNLCRDICAEWYLHARERRQDLSVGECPAGAWVVGNEAMLREMLANLLHNAVSYTPAGGSISVTVERSDSTLCILV
DDSGPGIPSADRERVFERFVRIAGTLGAGSGLGLAIVRQICEAHQGSVQLESGDKGGLRVRVTLPAAPAAPPAVA

Sequences:

>Translated_475_residues
MARQPSATSLRRTLLWRLALALLTVGIVSAFASYRTALKEANQAHDRTLLASTRSIAERIHVTNGRVTVNVPYGALDTFQ
IDARGRIFYRVLDPAGHFVSGEKDFPAMPANVPRSEDYPALVHFYDDAYAGTPLRVAALWQPVTEGGQQGVALVQVGESL
EMRDDMARRLLFTMLWQQAAMIGVSMTLLALTVAATLRPLKRLQDRIQARRASDLAPVEGDDLPREIQPLLQTLNQYLER
LRVIVENQKRFLDDAAHQLRTSLTLVRGHVDQRIRASDHGGDLAEVKAAIDRTVRLTNQLLTLARTGDGDVLAPDGDAMQ
RIELGNLCRDICAEWYLHARERRQDLSVGECPAGAWVVGNEAMLREMLANLLHNAVSYTPAGGSISVTVERSDSTLCILV
DDSGPGIPSADRERVFERFVRIAGTLGAGSGLGLAIVRQICEAHQGSVQLESGDKGGLRVRVTLPAAPAAPPAVA
>Mature_474_residues
ARQPSATSLRRTLLWRLALALLTVGIVSAFASYRTALKEANQAHDRTLLASTRSIAERIHVTNGRVTVNVPYGALDTFQI
DARGRIFYRVLDPAGHFVSGEKDFPAMPANVPRSEDYPALVHFYDDAYAGTPLRVAALWQPVTEGGQQGVALVQVGESLE
MRDDMARRLLFTMLWQQAAMIGVSMTLLALTVAATLRPLKRLQDRIQARRASDLAPVEGDDLPREIQPLLQTLNQYLERL
RVIVENQKRFLDDAAHQLRTSLTLVRGHVDQRIRASDHGGDLAEVKAAIDRTVRLTNQLLTLARTGDGDVLAPDGDAMQR
IELGNLCRDICAEWYLHARERRQDLSVGECPAGAWVVGNEAMLREMLANLLHNAVSYTPAGGSISVTVERSDSTLCILVD
DSGPGIPSADRERVFERFVRIAGTLGAGSGLGLAIVRQICEAHQGSVQLESGDKGGLRVRVTLPAAPAAPPAVA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=328, Percent_Identity=28.6585365853659, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790551, Length=286, Percent_Identity=31.1188811188811, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786783, Length=317, Percent_Identity=27.7602523659306, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790346, Length=246, Percent_Identity=29.2682926829268, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788279, Length=306, Percent_Identity=27.4509803921569, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=29.4964028776978, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=29.3333333333333, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790861, Length=325, Percent_Identity=26.4615384615385, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=31.1111111111111, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=29.1479820627803, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=27.3092369477912, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=243, Percent_Identity=26.7489711934156, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=309, Percent_Identity=26.2135922330097, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=214, Percent_Identity=28.9719626168224, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=311, Percent_Identity=25.7234726688103, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51835; Mature: 51704

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQPSATSLRRTLLWRLALALLTVGIVSAFASYRTALKEANQAHDRTLLASTRSIAERI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVTNGRVTVNVPYGALDTFQIDARGRIFYRVLDPAGHFVSGEKDFPAMPANVPRSEDYPA
EECCCEEEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCE
LVHFYDDAYAGTPLRVAALWQPVTEGGQQGVALVQVGESLEMRDDMARRLLFTMLWQQAA
EEEEECCCCCCCCEEHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
MIGVSMTLLALTVAATLRPLKRLQDRIQARRASDLAPVEGDDLPREIQPLLQTLNQYLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRVIVENQKRFLDDAAHQLRTSLTLVRGHVDQRIRASDHGGDLAEVKAAIDRTVRLTNQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LTLARTGDGDVLAPDGDAMQRIELGNLCRDICAEWYLHARERRQDLSVGECPAGAWVVGN
HHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECC
EAMLREMLANLLHNAVSYTPAGGSISVTVERSDSTLCILVDDSGPGIPSADRERVFERFV
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHH
RIAGTLGAGSGLGLAIVRQICEAHQGSVQLESGDKGGLRVRVTLPAAPAAPPAVA
HHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ARQPSATSLRRTLLWRLALALLTVGIVSAFASYRTALKEANQAHDRTLLASTRSIAERI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVTNGRVTVNVPYGALDTFQIDARGRIFYRVLDPAGHFVSGEKDFPAMPANVPRSEDYPA
EECCCEEEEEECCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCE
LVHFYDDAYAGTPLRVAALWQPVTEGGQQGVALVQVGESLEMRDDMARRLLFTMLWQQAA
EEEEECCCCCCCCEEHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
MIGVSMTLLALTVAATLRPLKRLQDRIQARRASDLAPVEGDDLPREIQPLLQTLNQYLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRVIVENQKRFLDDAAHQLRTSLTLVRGHVDQRIRASDHGGDLAEVKAAIDRTVRLTNQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LTLARTGDGDVLAPDGDAMQRIELGNLCRDICAEWYLHARERRQDLSVGECPAGAWVVGN
HHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECC
EAMLREMLANLLHNAVSYTPAGGSISVTVERSDSTLCILVDDSGPGIPSADRERVFERFV
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHH
RIAGTLGAGSGLGLAIVRQICEAHQGSVQLESGDKGGLRVRVTLPAAPAAPPAVA
HHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]