| Definition | Cupriavidus metallidurans CH34 chromosome, complete genome. |
|---|---|
| Accession | NC_007973 |
| Length | 3,928,089 |
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The map label for this gene is murC [H]
Identifier: 94312058
GI number: 94312058
Start: 3389180
End: 3390595
Strand: Reverse
Name: murC [H]
Synonym: Rmet_3127
Alternate gene names: 94312058
Gene position: 3390595-3389180 (Counterclockwise)
Preceding gene: 94312059
Following gene: 94312057
Centisome position: 86.32
GC content: 66.03
Gene sequence:
>1416_bases ATGAAGCATATTGTCAAGAACATCCACTTCGTAGGCATTGGCGGGGCCGGCATGAGCGGCATCGCCGAGGTCCTGCTGAA TCTGGGCTACAAGGTCTCGGGTTCCGACGTGGGCAGCAATGCCGCCACGCGGCGCCTGGCTTCGCTCGGCGCGCGCGTGG CTCATGGCCACGACGCGGAAAACGTGACGGGCGCCAATGCCGTGGTGGTATCCACCGCGGTGACCAACGACAACCCCGAA GTGCTGGCAGCCCGCGCCAGGCGTATCCCGGTGGTGCCGCGCGCGGTGATGCTGGCCGAGCTGATGCGCCTGAAGCAGGG CGTGGCTATCGCCGGCACCCATGGCAAGACCACCACGACCAGCCTGGTGGCATCGGTGCTGGCCGAAGGCGGGCTAGATC CGACGTTCGTGATCGGTGGCCGCCTGAATTCAGCCGGCGCTAACGCGCGGCTCGGCACGGGCGATTTCATCGTCGCGGAA GCCGACGAGTCCGACGCGTCGTTCCTGAACCTGTTTCCGGTGATGGAAGTCATCACCAATATCGACGCCGACCACATGGA CACCTACGGGCATGATTTTGCCCGGCTCAAGCAGGCGTTCGTGGAGTTTACCCAGCGCCTGCCGTTCTACGGCATTGCCG TGCTGTGTGTCGATGACCCGAACGTGCGCGAGATCCTGCCGTTCGTGTCCAAGCCGGTGGTGCGCTACGGTTTTGCCGAG GACGCGCAGATTCGTGCGGTCAATGCGCGCGCCGTTGATGGACAGATGCACTTCACCGTGCTGCGCCAGCTCAATGGCCA CGCCGAGCCGCCGCTCGACATCGTGCTGAACCTGCCGGGGATTCACAACGTCCAGAACGCGCTGGCCGCCATCGCGATTG CCACCGAACTCGAAGTGCCGGACGCGTCGATCGTCAAGGCGCTGCGCGAGTTTCACGGCGTGGGCCGCCGCTTCCAGCGC TACGGCGAGGTGGCGACGCCCGACGGTTCGGGCACGTTCACGCTGGTCGACGATTACGGCCATCACCCGGTGGAGATGGC CGCGACGCTGGCTGCCGCGCGCGGCGCGTTCCCGGACCGCCGCCTGGTGCTGGCATTCCAGCCCCATCGCTTCACACGCA CGCGCGACTGTTTCGAGGACTTCGTCAAGGTGCTGGGCACCGTCGACGCGCTGCTGCTGGCGGAGGTGTACGCCGCCGGC GAATCGCCGATCGTCGCGGCCGATGGCCGCGCGCTGACGCGCGCGCTGCGCGTTGCAAACAAGGTAGAACCCGTTTTTGT CGAGCAGATCGAGGACATGCCCCAGGCCATCCTGAATGCCGTACGGCCCGGCGATGTGGTCGTAACCATGGGCGCTGGCT CGATCGGCGCAGTGCCGGGCCAGTTGGTGTCGCATCAACAAGGGGGGCAGCAATGA
Upstream 100 bases:
>100_bases GACATGGCGCGCGCTGCGCGTGGCCTGGCCAAACCGGAGGCAACCCGGCGCGTCGCCGAGATCTGCAGCCAGTTGGCGGG TAAATCGTGAAACGAATTCA
Downstream 100 bases:
>100_bases GCTTCGTCGCCCATCCCAATATCGATCCGAAGTCGCTGGGCAAGGTTGGCGTGCTGCTGGGTGGCAAGTCCGCCGAGCGC GAGATCTCGCTGCTGTCCGG
Product: UDP-N-acetylmuramate--L-alanine ligase
Products: NA
Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]
Number of amino acids: Translated: 471; Mature: 471
Protein sequence:
>471_residues MKHIVKNIHFVGIGGAGMSGIAEVLLNLGYKVSGSDVGSNAATRRLASLGARVAHGHDAENVTGANAVVVSTAVTNDNPE VLAARARRIPVVPRAVMLAELMRLKQGVAIAGTHGKTTTTSLVASVLAEGGLDPTFVIGGRLNSAGANARLGTGDFIVAE ADESDASFLNLFPVMEVITNIDADHMDTYGHDFARLKQAFVEFTQRLPFYGIAVLCVDDPNVREILPFVSKPVVRYGFAE DAQIRAVNARAVDGQMHFTVLRQLNGHAEPPLDIVLNLPGIHNVQNALAAIAIATELEVPDASIVKALREFHGVGRRFQR YGEVATPDGSGTFTLVDDYGHHPVEMAATLAAARGAFPDRRLVLAFQPHRFTRTRDCFEDFVKVLGTVDALLLAEVYAAG ESPIVAADGRALTRALRVANKVEPVFVEQIEDMPQAILNAVRPGDVVVTMGAGSIGAVPGQLVSHQQGGQQ
Sequences:
>Translated_471_residues MKHIVKNIHFVGIGGAGMSGIAEVLLNLGYKVSGSDVGSNAATRRLASLGARVAHGHDAENVTGANAVVVSTAVTNDNPE VLAARARRIPVVPRAVMLAELMRLKQGVAIAGTHGKTTTTSLVASVLAEGGLDPTFVIGGRLNSAGANARLGTGDFIVAE ADESDASFLNLFPVMEVITNIDADHMDTYGHDFARLKQAFVEFTQRLPFYGIAVLCVDDPNVREILPFVSKPVVRYGFAE DAQIRAVNARAVDGQMHFTVLRQLNGHAEPPLDIVLNLPGIHNVQNALAAIAIATELEVPDASIVKALREFHGVGRRFQR YGEVATPDGSGTFTLVDDYGHHPVEMAATLAAARGAFPDRRLVLAFQPHRFTRTRDCFEDFVKVLGTVDALLLAEVYAAG ESPIVAADGRALTRALRVANKVEPVFVEQIEDMPQAILNAVRPGDVVVTMGAGSIGAVPGQLVSHQQGGQQ >Mature_471_residues MKHIVKNIHFVGIGGAGMSGIAEVLLNLGYKVSGSDVGSNAATRRLASLGARVAHGHDAENVTGANAVVVSTAVTNDNPE VLAARARRIPVVPRAVMLAELMRLKQGVAIAGTHGKTTTTSLVASVLAEGGLDPTFVIGGRLNSAGANARLGTGDFIVAE ADESDASFLNLFPVMEVITNIDADHMDTYGHDFARLKQAFVEFTQRLPFYGIAVLCVDDPNVREILPFVSKPVVRYGFAE DAQIRAVNARAVDGQMHFTVLRQLNGHAEPPLDIVLNLPGIHNVQNALAAIAIATELEVPDASIVKALREFHGVGRRFQR YGEVATPDGSGTFTLVDDYGHHPVEMAATLAAARGAFPDRRLVLAFQPHRFTRTRDCFEDFVKVLGTVDALLLAEVYAAG ESPIVAADGRALTRALRVANKVEPVFVEQIEDMPQAILNAVRPGDVVVTMGAGSIGAVPGQLVSHQQGGQQ
Specific function: Cell wall formation [H]
COG id: COG0773
COG function: function code M; UDP-N-acetylmuramate-alanine ligase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786279, Length=457, Percent_Identity=53.6105032822757, Blast_Score=439, Evalue=1e-124, Organism=Escherichia coli, GI1790680, Length=471, Percent_Identity=28.6624203821656, Blast_Score=153, Evalue=3e-38,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR016040 - InterPro: IPR005758 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.8 [H]
Molecular weight: Translated: 50017; Mature: 50017
Theoretical pI: Translated: 6.35; Mature: 6.35
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKHIVKNIHFVGIGGAGMSGIAEVLLNLGYKVSGSDVGSNAATRRLASLGARVAHGHDAE CCCHHCCEEEEEECCCCHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCC NVTGANAVVVSTAVTNDNPEVLAARARRIPVVPRAVMLAELMRLKQGVAIAGTHGKTTTT CCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHH SLVASVLAEGGLDPTFVIGGRLNSAGANARLGTGDFIVAEADESDASFLNLFPVMEVITN HHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC IDADHMDTYGHDFARLKQAFVEFTQRLPFYGIAVLCVDDPNVREILPFVSKPVVRYGFAE CCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCC DAQIRAVNARAVDGQMHFTVLRQLNGHAEPPLDIVLNLPGIHNVQNALAAIAIATELEVP CCEEEEEECEEECCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCC DASIVKALREFHGVGRRFQRYGEVATPDGSGTFTLVDDYGHHPVEMAATLAAARGAFPDR CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCC RLVLAFQPHRFTRTRDCFEDFVKVLGTVDALLLAEVYAAGESPIVAADGRALTRALRVAN EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH KVEPVFVEQIEDMPQAILNAVRPGDVVVTMGAGSIGAVPGQLVSHQQGGQQ CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCCCC >Mature Secondary Structure MKHIVKNIHFVGIGGAGMSGIAEVLLNLGYKVSGSDVGSNAATRRLASLGARVAHGHDAE CCCHHCCEEEEEECCCCHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCC NVTGANAVVVSTAVTNDNPEVLAARARRIPVVPRAVMLAELMRLKQGVAIAGTHGKTTTT CCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHH SLVASVLAEGGLDPTFVIGGRLNSAGANARLGTGDFIVAEADESDASFLNLFPVMEVITN HHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC IDADHMDTYGHDFARLKQAFVEFTQRLPFYGIAVLCVDDPNVREILPFVSKPVVRYGFAE CCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCHHHCCCCC DAQIRAVNARAVDGQMHFTVLRQLNGHAEPPLDIVLNLPGIHNVQNALAAIAIATELEVP CCEEEEEECEEECCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCC DASIVKALREFHGVGRRFQRYGEVATPDGSGTFTLVDDYGHHPVEMAATLAAARGAFPDR CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCC RLVLAFQPHRFTRTRDCFEDFVKVLGTVDALLLAEVYAAGESPIVAADGRALTRALRVAN EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH KVEPVFVEQIEDMPQAILNAVRPGDVVVTMGAGSIGAVPGQLVSHQQGGQQ CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA