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The map label for this gene is dapB

Identifier: 94311906

GI number: 94311906

Start: 3233552

End: 3234349

Strand: Reverse

Name: dapB

Synonym: Rmet_2974

Alternate gene names: 94311906

Gene position: 3234349-3233552 (Counterclockwise)

Preceding gene: 94311907

Following gene: 94311905

Centisome position: 82.34

GC content: 65.04

Gene sequence:

>798_bases
ATGAAAATCGCCATTGCAGGGGCTTCCGGCCGCATGGGTCGCATGTTGATCGAAACGGTGCTCAATACCGACGGCGTGAC
GCTGGCCGGCGCGCTCGACGTGCCAGGTGCTGCGGCGCTGGGCCAGGATGCCGGGCTGTTTCTGGGCCGCGAGACGGGCA
TCAAGATCTCCTCTGACATCGAGGCCGTGCTCTCGGCCGCCGATTGCCTGATTGATTTCACCCGCCCCGAGGGCACGCTG
GCGCACCTGGCGGTGGCCAAGCGCCTCGGCAAGAAGATGGTGATTGGTACCACCGGTTTCGATGCCGCCGGCAAGCAGGC
ACTGGCCGATGCCGCCAAGTCGATCGGCGTGGTGTTTGCCGCGAACATGAGCGTCGGCGTCAATGCCACGTTCAAGCTGC
TGGAAGTGGCGGCCAAGCTGCTTTCCACGGGCTACGACATCGAGATCATCGAAGCGCACCATCGCCACAAGGTCGACGCG
CCGTCGGGCACGGCGCTGGCGATGGGCGAAGTGGTCGCCAAGGCCATCGGCCGCGATCTCGACGAATGCGCGGTCTACGC
GCGCGAAGGCCATACTGGCCCGCGCGACGCGAAGTCGATTGGCTTCGCGACGGTCCGTGGCGGCGATATCGTCGGCGATC
ACACGGTGATGTTCGCCGGCATCGGCGAGCGCATCGAGATCAGCCACAAGTCGTCCAGCCGCCAGTCGTATGCCGATGGT
GCTGTGCGTGCGGCGCGTTTCCTGGCCGACAAGCCGAGCGGCATGTTTGACATGCAGGATGTGCTGGGCCTGAAGTAA

Upstream 100 bases:

>100_bases
TCCGGCCAAACCTGCCAGCTAAACGCGGCGGCGAGTCCATTTCAGACACCCAAGCCGTCCGGTCGAATGCCGGACGGTTT
TCATTCCGACATACCCAATC

Downstream 100 bases:

>100_bases
GCCCGCAAGCACGCCCGGCGCGGCCCAGAGGCGGGCCGTTCCAGCCTTTCCGTGCGAGCCGTGGCGGACATACGCCACGG
TTATAATCGTCTCTTTCGCA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKIAIAGASGRMGRMLIETVLNTDGVTLAGALDVPGAAALGQDAGLFLGRETGIKISSDIEAVLSAADCLIDFTRPEGTL
AHLAVAKRLGKKMVIGTTGFDAAGKQALADAAKSIGVVFAANMSVGVNATFKLLEVAAKLLSTGYDIEIIEAHHRHKVDA
PSGTALAMGEVVAKAIGRDLDECAVYAREGHTGPRDAKSIGFATVRGGDIVGDHTVMFAGIGERIEISHKSSSRQSYADG
AVRAARFLADKPSGMFDMQDVLGLK

Sequences:

>Translated_265_residues
MKIAIAGASGRMGRMLIETVLNTDGVTLAGALDVPGAAALGQDAGLFLGRETGIKISSDIEAVLSAADCLIDFTRPEGTL
AHLAVAKRLGKKMVIGTTGFDAAGKQALADAAKSIGVVFAANMSVGVNATFKLLEVAAKLLSTGYDIEIIEAHHRHKVDA
PSGTALAMGEVVAKAIGRDLDECAVYAREGHTGPRDAKSIGFATVRGGDIVGDHTVMFAGIGERIEISHKSSSRQSYADG
AVRAARFLADKPSGMFDMQDVLGLK
>Mature_265_residues
MKIAIAGASGRMGRMLIETVLNTDGVTLAGALDVPGAAALGQDAGLFLGRETGIKISSDIEAVLSAADCLIDFTRPEGTL
AHLAVAKRLGKKMVIGTTGFDAAGKQALADAAKSIGVVFAANMSVGVNATFKLLEVAAKLLSTGYDIEIIEAHHRHKVDA
PSGTALAMGEVVAKAIGRDLDECAVYAREGHTGPRDAKSIGFATVRGGDIVGDHTVMFAGIGERIEISHKSSSRQSYADG
AVRAARFLADKPSGMFDMQDVLGLK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=266, Percent_Identity=62.406015037594, Blast_Score=313, Evalue=9e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_RALME (Q1LJ29)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_585116.1
- ProteinModelPortal:   Q1LJ29
- SMR:   Q1LJ29
- STRING:   Q1LJ29
- GeneID:   4039802
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_2974
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GALKACE
- PhylomeDB:   Q1LJ29
- ProtClustDB:   PRK00048
- BioCyc:   RMET266264:RMET_2974-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27407; Mature: 27407

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIAGASGRMGRMLIETVLNTDGVTLAGALDVPGAAALGQDAGLFLGRETGIKISSDI
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCEEEECCCCCEEHHHH
EAVLSAADCLIDFTRPEGTLAHLAVAKRLGKKMVIGTTGFDAAGKQALADAAKSIGVVFA
HHHHHHHHHHEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCEEEE
ANMSVGVNATFKLLEVAAKLLSTGYDIEIIEAHHRHKVDAPSGTALAMGEVVAKAIGRDL
ECCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCH
DECAVYAREGHTGPRDAKSIGFATVRGGDIVGDHTVMFAGIGERIEISHKSSSRQSYADG
HHHHHHHHCCCCCCCCHHHCCEEEECCCCEECCCEEEEECCCCEEEECCCCCCHHHHHHH
AVRAARFLADKPSGMFDMQDVLGLK
HHHHHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKIAIAGASGRMGRMLIETVLNTDGVTLAGALDVPGAAALGQDAGLFLGRETGIKISSDI
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCEEEECCCCCEEHHHH
EAVLSAADCLIDFTRPEGTLAHLAVAKRLGKKMVIGTTGFDAAGKQALADAAKSIGVVFA
HHHHHHHHHHEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCEEEE
ANMSVGVNATFKLLEVAAKLLSTGYDIEIIEAHHRHKVDAPSGTALAMGEVVAKAIGRDL
ECCEECCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCH
DECAVYAREGHTGPRDAKSIGFATVRGGDIVGDHTVMFAGIGERIEISHKSSSRQSYADG
HHHHHHHHCCCCCCCCHHHCCEEEECCCCEECCCEEEEECCCCEEEECCCCCCHHHHHHH
AVRAARFLADKPSGMFDMQDVLGLK
HHHHHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA