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The map label for this gene is vsrB [H]

Identifier: 94311813

GI number: 94311813

Start: 3132458

End: 3134356

Strand: Reverse

Name: vsrB [H]

Synonym: Rmet_2881

Alternate gene names: 94311813

Gene position: 3134356-3132458 (Counterclockwise)

Preceding gene: 94311814

Following gene: 94311810

Centisome position: 79.79

GC content: 63.67

Gene sequence:

>1899_bases
ATGATATGCCCCACTTGCAACAAAATTGCGCGATTTCTGCAACGTCGGCAGACTTGTCTGATGCCAGTTGCAGCGACGAA
GAACGTCGCCTTACGTGCCACGCCACACTTGAACGCGCTGCTCAACAAGATCCTGCCCCCGCCCGGGCCGCAACTGGACA
CCGAAACGCGAGCCAAGCTGCTCGTCACCGTTCATCGTGTCTCCCCCACGGGCATTGCATCCTCGGCCCTGCTGCCGGGA
CTGACCGCGTACACGTTCTGGAACGAAGCCAACCACGTGGCGCTGGTGATCTGGTGCGCCATCATGCTGCTGCTGACCAT
CGGCGGGATGTGGTTCTACCTCGGGTTCCAGCGCGATATGGGTAGGTTGAGCCGCTCGGCGCACACGCGCAAGTGGTGGA
ACAATATGCGCGCCATTGCGTTCCTGACGGGACTGACCTGGGGCAGTTCGGCGCTGCTGCATCTGTATTCGTCGTCCGTG
GTGTTCTCGAGCGTGCTGTATCTGCTGACGTTGGGTGTGCTCGCGGGCGGCGCCACGTCGCAGTCGCCCATCCCATCGAA
CCTGGTCTTTGCCGGCGTGCCGATCCTTGTGCCGAATGTGCTGCTGGCTGACTTTGCCTTTCCGGGCCACGGCACCTATG
TGCAATTGCTGCTGGCTATCTACGCGCTGATGCTGGCACGGCACTCGCTGAATCTGCAGCACACGCTGGTGCGGGCCATC
CAGCTCGAATCCGAAAGCCGCCGGCTCGCCAAGCAGTTTCAGGAAGAGAAGGAACGGGCACTTCATGCCAGTGAGGAGAA
ATCCCGCTTCCTGGCGGCCGCGAGTCACGACCTGCGCCAGCCTGTTCATGCCCTGGTGATGCTGGTCGAAGCGTTGCGTG
CGCGCAACCAATCGAGTTCGCTCCACCCGCTCGTCGAGCAGGTGGCCGCCGGGACGCAGACCATCGACCTGCTGTTCCGG
TCCCTGCTTGACCTGTCCAAGCTTGAAGGGCGCAAGGTGTTACCAACGCTGGAGCCATGCGAACTTAATTCGCTGATCCA
TGACGTGATGAGCCAGTTCGCCGCCGATGCGCGCGAAAGCGGTCTGACGCTGACGCCACGCGTGCCTGACGAACTGTTCG
CCATGGCCGAGCCGGTGCTGCTGCGGCGGGCGCTGTTCAACCTCGTGCAGAACGCGCTGCGCTATACGAAGCGCGGCGGC
ATTCTGGTAACCGCACGACAGCGCCGCAAGCACGTGCGGCTGGAGGTCTGGGACACCGGTGCGGGCATCACGCCCGAGCA
CCTGCCGGAAATTTTCTCGCCGTACTACCAGGTTCACAATCCGCAGCGCGATCCGTCGCAGGGTCTTGGTCTGGGGCTCG
CGATCTTCCGGGAATGCGTGCGTCTGATGCGCGGGACTTACGGCGTGCGCTCGGTGCCGGGCAAGGGATCGGTATTCTGG
TTCGCGCTGGCGCCGGTGCCCGAGGAGACCGTAGCCAGTGTTCGGGCGATGCGGGCGAATGCGCAGGCGGAAGAAGCGCG
ACACGATCGTTTACGTGGCACTGTGCTGGTGGTCGATGACGATAGCCAGATTCGCAAGGCGTGGATCGCCTTGATGGAGG
CCTGGGGCATTCGCGTGGCATGTGCCGCGCACGGGGGAGAGGCCGACCGTCTCTTCGCGAAGGGTCTCAAGCCGGACATT
ATCTTCTGTGACCTGCGCTTGCCCGGCAACGAGAACGGGCTCGATTTGCTGGAGCGCTGGCAGACCTCGCAGCCTCAGGC
ACGCAGCGCGCTGCTGACGGGCGATCTGAAGTCCGCGGCGCTGCAGGCGGCCGAGGAGGCAGGCTACTTCGTCCTGCCGA
AACCGGTGGACCCGGCGAACCTGCGCATGTTGCTGCGCCGCTGGTTGCCCACGGCATGA

Upstream 100 bases:

>100_bases
GCGCGCGCTTTCGACACACGCCCCCCACAAACGTGGTGCTTTTGACAAATTTGTGGGTTATTGGGGCGCCTCGCAATGGC
GCGGCGCCGCAAAAATCGGC

Downstream 100 bases:

>100_bases
ACGCATGAATGACAACGCCGCCCTTGAGGCGGCGTTGTCATTCATGCGTGGCGATGTTCACTGCCTCACTGGCGCAGGCG
AAAACGCTCCATGCGCGACA

Product: Response regulator receiver :ATP-binding region, ATPase-like:Histidine kinase A, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MICPTCNKIARFLQRRQTCLMPVAATKNVALRATPHLNALLNKILPPPGPQLDTETRAKLLVTVHRVSPTGIASSALLPG
LTAYTFWNEANHVALVIWCAIMLLLTIGGMWFYLGFQRDMGRLSRSAHTRKWWNNMRAIAFLTGLTWGSSALLHLYSSSV
VFSSVLYLLTLGVLAGGATSQSPIPSNLVFAGVPILVPNVLLADFAFPGHGTYVQLLLAIYALMLARHSLNLQHTLVRAI
QLESESRRLAKQFQEEKERALHASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSSSLHPLVEQVAAGTQTIDLLFR
SLLDLSKLEGRKVLPTLEPCELNSLIHDVMSQFAADARESGLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGG
ILVTARQRRKHVRLEVWDTGAGITPEHLPEIFSPYYQVHNPQRDPSQGLGLGLAIFRECVRLMRGTYGVRSVPGKGSVFW
FALAPVPEETVASVRAMRANAQAEEARHDRLRGTVLVVDDDSQIRKAWIALMEAWGIRVACAAHGGEADRLFAKGLKPDI
IFCDLRLPGNENGLDLLERWQTSQPQARSALLTGDLKSAALQAAEEAGYFVLPKPVDPANLRMLLRRWLPTA

Sequences:

>Translated_632_residues
MICPTCNKIARFLQRRQTCLMPVAATKNVALRATPHLNALLNKILPPPGPQLDTETRAKLLVTVHRVSPTGIASSALLPG
LTAYTFWNEANHVALVIWCAIMLLLTIGGMWFYLGFQRDMGRLSRSAHTRKWWNNMRAIAFLTGLTWGSSALLHLYSSSV
VFSSVLYLLTLGVLAGGATSQSPIPSNLVFAGVPILVPNVLLADFAFPGHGTYVQLLLAIYALMLARHSLNLQHTLVRAI
QLESESRRLAKQFQEEKERALHASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSSSLHPLVEQVAAGTQTIDLLFR
SLLDLSKLEGRKVLPTLEPCELNSLIHDVMSQFAADARESGLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGG
ILVTARQRRKHVRLEVWDTGAGITPEHLPEIFSPYYQVHNPQRDPSQGLGLGLAIFRECVRLMRGTYGVRSVPGKGSVFW
FALAPVPEETVASVRAMRANAQAEEARHDRLRGTVLVVDDDSQIRKAWIALMEAWGIRVACAAHGGEADRLFAKGLKPDI
IFCDLRLPGNENGLDLLERWQTSQPQARSALLTGDLKSAALQAAEEAGYFVLPKPVDPANLRMLLRRWLPTA
>Mature_632_residues
MICPTCNKIARFLQRRQTCLMPVAATKNVALRATPHLNALLNKILPPPGPQLDTETRAKLLVTVHRVSPTGIASSALLPG
LTAYTFWNEANHVALVIWCAIMLLLTIGGMWFYLGFQRDMGRLSRSAHTRKWWNNMRAIAFLTGLTWGSSALLHLYSSSV
VFSSVLYLLTLGVLAGGATSQSPIPSNLVFAGVPILVPNVLLADFAFPGHGTYVQLLLAIYALMLARHSLNLQHTLVRAI
QLESESRRLAKQFQEEKERALHASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSSSLHPLVEQVAAGTQTIDLLFR
SLLDLSKLEGRKVLPTLEPCELNSLIHDVMSQFAADARESGLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGG
ILVTARQRRKHVRLEVWDTGAGITPEHLPEIFSPYYQVHNPQRDPSQGLGLGLAIFRECVRLMRGTYGVRSVPGKGSVFW
FALAPVPEETVASVRAMRANAQAEEARHDRLRGTVLVVDDDSQIRKAWIALMEAWGIRVACAAHGGEADRLFAKGLKPDI
IFCDLRLPGNENGLDLLERWQTSQPQARSALLTGDLKSAALQAAEEAGYFVLPKPVDPANLRMLLRRWLPTA

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=331, Percent_Identity=29.9093655589124, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=29.1187739463602, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788713, Length=345, Percent_Identity=24.9275362318841, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081816, Length=334, Percent_Identity=26.6467065868263, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789149, Length=278, Percent_Identity=27.3381294964029, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=30.0813008130081, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=30.0429184549356, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=29.4871794871795, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=30.4545454545455, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=28.75, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=27.7551020408163, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=28.6290322580645, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789808, Length=217, Percent_Identity=25.3456221198157, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69977; Mature: 69977

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICPTCNKIARFLQRRQTCLMPVAATKNVALRATPHLNALLNKILPPPGPQLDTETRAKL
CCCCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHEE
LVTVHRVSPTGIASSALLPGLTAYTFWNEANHVALVIWCAIMLLLTIGGMWFYLGFQRDM
EEEEEECCCCCCCHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLSRSAHTRKWWNNMRAIAFLTGLTWGSSALLHLYSSSVVFSSVLYLLTLGVLAGGATS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QSPIPSNLVFAGVPILVPNVLLADFAFPGHGTYVQLLLAIYALMLARHSLNLQHTLVRAI
CCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QLESESRRLAKQFQEEKERALHASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSSS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LHPLVEQVAAGTQTIDLLFRSLLDLSKLEGRKVLPTLEPCELNSLIHDVMSQFAADARES
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGGILVTARQRRKHVRLEVWDTG
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEEEEECC
AGITPEHLPEIFSPYYQVHNPQRDPSQGLGLGLAIFRECVRLMRGTYGVRSVPGKGSVFW
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
FALAPVPEETVASVRAMRANAQAEEARHDRLRGTVLVVDDDSQIRKAWIALMEAWGIRVA
EEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCEEE
CAAHGGEADRLFAKGLKPDIIFCDLRLPGNENGLDLLERWQTSQPQARSALLTGDLKSAA
EECCCCCHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHH
LQAAEEAGYFVLPKPVDPANLRMLLRRWLPTA
HHHHHHCCEEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MICPTCNKIARFLQRRQTCLMPVAATKNVALRATPHLNALLNKILPPPGPQLDTETRAKL
CCCCCHHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHEE
LVTVHRVSPTGIASSALLPGLTAYTFWNEANHVALVIWCAIMLLLTIGGMWFYLGFQRDM
EEEEEECCCCCCCHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRLSRSAHTRKWWNNMRAIAFLTGLTWGSSALLHLYSSSVVFSSVLYLLTLGVLAGGATS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QSPIPSNLVFAGVPILVPNVLLADFAFPGHGTYVQLLLAIYALMLARHSLNLQHTLVRAI
CCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QLESESRRLAKQFQEEKERALHASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSSS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LHPLVEQVAAGTQTIDLLFRSLLDLSKLEGRKVLPTLEPCELNSLIHDVMSQFAADARES
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGGILVTARQRRKHVRLEVWDTG
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEEEEECC
AGITPEHLPEIFSPYYQVHNPQRDPSQGLGLGLAIFRECVRLMRGTYGVRSVPGKGSVFW
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
FALAPVPEETVASVRAMRANAQAEEARHDRLRGTVLVVDDDSQIRKAWIALMEAWGIRVA
EEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCEEE
CAAHGGEADRLFAKGLKPDIIFCDLRLPGNENGLDLLERWQTSQPQARSALLTGDLKSAA
EECCCCCHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHH
LQAAEEAGYFVLPKPVDPANLRMLLRRWLPTA
HHHHHHCCEEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]