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The map label for this gene is nadA [H]

Identifier: 94311806

GI number: 94311806

Start: 3123820

End: 3124974

Strand: Reverse

Name: nadA [H]

Synonym: Rmet_2874

Alternate gene names: 94311806

Gene position: 3124974-3123820 (Counterclockwise)

Preceding gene: 94311807

Following gene: 94311805

Centisome position: 79.55

GC content: 64.33

Gene sequence:

>1155_bases
ATGACCCCACAAACGATCAAGAGCGTCGAGTTCGAGAAGCCGAACCTGACGGACCCTGACGCGGCCGCCGGTGGTAGCTG
CGTCGCGCACGCCTGGGCCAAGGTGCCCCCGGCGCTGACACCCGATGAGCGCCAGGCGCTCAAGTCCCGCATTCGCAAGT
TGCTGAAAGAGCGCAATGCGGTGCTGGTAGCGCATTACTACGTCGATGCCGACCTGCAGGATCTTGCCGAGGAAACCGGC
GGCTGCGTGTCCGATTCGCTGGAAATGGCCCGCTTCGGGCGCGATCACGATGCCAAGACGCTCGTGGTGGCCGGTGTACG
ATTCATGGGCGAGACCGCCAAGATCCTGAGCCCCGAGAAGACCATCCTGATGCCGGATCTGGACGCCACCTGCTCGCTGG
ACCTGGGCTGCCCGGCCGACGATTTCTCGGCATTCTGCGATGCGCACCCGGATCGCACCGTGGTGGTCTATGCCAACACC
AGCGCGGCGGTGAAGGCGCGCGCCGACTGGATGGTGACGTCGAGCATCGGCCTGAAGATCGTCGAGCATCTGCACGCGCG
CGGCGAGAAGATCCTGTGGGCGCCGGACAAGCATCTGGGCAGCTACATCCAGCAGCAGACCGGCGCCGACATGCTGTTGT
GGCAGGGCTCGTGCCTGGTGCACGACGAGTTCAAGGGTATCGAACTCGATCTGCTGCGCCGCGAGCATCCGAAGGCCAAG
ATCCTGGTCCACCCGGAGTCGCCGGCCAACGTGGTTGCGCAGGCTGACGTGGTTGGCTCGACCAGCCAGCTGATCGCCGC
GGCCCAGCAGTTGGACGCCAACGAGTTCATCGTTGCCACCGATAACGGCATCCTGCACAAGATGCGTATGGCCGCGCCGG
GCAAGATGTTCATCGAGGCCCCGACCGCCGGCAACAGCGCCACCTGCAAGAGCTGCGCGCATTGCCCGTGGATGGCCATG
AATGCGCTGACCAATCTGGCCGAAGTCCTCGAGACCGGCCGCAACGAAATTCACGTCGACGCCGACATCGGACGACGCGC
CGTAACGTGTATCAACCGGATGCTCGATTTCGCCGCGCAGCAGAAAGCCAATGTTCGCCCCGCAGCCGATCTCGCCAAGG
AATCGGCACTGTTCAGCGGAGTTGGCCCGGCATGA

Upstream 100 bases:

>100_bases
CCAGGCGGGGCTTTTCTTTTGGCTAAACTTCTCCATGTGATGGCACAGACCGCGCGTTCACAGCGCGGCGGCCAACGGTG
CGCCGAGGAGTACTGCAGAG

Downstream 100 bases:

>100_bases
GCGTGAATTCCGTATTCGATAGCTACGGCCCCGCGCTGCGTGTGGCGCTGGCCGCCAACGTCAAGGCGGCGATTGCCGAG
GATGTGGGGGCTGGTGACCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTPQTIKSVEFEKPNLTDPDAAAGGSCVAHAWAKVPPALTPDERQALKSRIRKLLKERNAVLVAHYYVDADLQDLAEETG
GCVSDSLEMARFGRDHDAKTLVVAGVRFMGETAKILSPEKTILMPDLDATCSLDLGCPADDFSAFCDAHPDRTVVVYANT
SAAVKARADWMVTSSIGLKIVEHLHARGEKILWAPDKHLGSYIQQQTGADMLLWQGSCLVHDEFKGIELDLLRREHPKAK
ILVHPESPANVVAQADVVGSTSQLIAAAQQLDANEFIVATDNGILHKMRMAAPGKMFIEAPTAGNSATCKSCAHCPWMAM
NALTNLAEVLETGRNEIHVDADIGRRAVTCINRMLDFAAQQKANVRPAADLAKESALFSGVGPA

Sequences:

>Translated_384_residues
MTPQTIKSVEFEKPNLTDPDAAAGGSCVAHAWAKVPPALTPDERQALKSRIRKLLKERNAVLVAHYYVDADLQDLAEETG
GCVSDSLEMARFGRDHDAKTLVVAGVRFMGETAKILSPEKTILMPDLDATCSLDLGCPADDFSAFCDAHPDRTVVVYANT
SAAVKARADWMVTSSIGLKIVEHLHARGEKILWAPDKHLGSYIQQQTGADMLLWQGSCLVHDEFKGIELDLLRREHPKAK
ILVHPESPANVVAQADVVGSTSQLIAAAQQLDANEFIVATDNGILHKMRMAAPGKMFIEAPTAGNSATCKSCAHCPWMAM
NALTNLAEVLETGRNEIHVDADIGRRAVTCINRMLDFAAQQKANVRPAADLAKESALFSGVGPA
>Mature_383_residues
TPQTIKSVEFEKPNLTDPDAAAGGSCVAHAWAKVPPALTPDERQALKSRIRKLLKERNAVLVAHYYVDADLQDLAEETGG
CVSDSLEMARFGRDHDAKTLVVAGVRFMGETAKILSPEKTILMPDLDATCSLDLGCPADDFSAFCDAHPDRTVVVYANTS
AAVKARADWMVTSSIGLKIVEHLHARGEKILWAPDKHLGSYIQQQTGADMLLWQGSCLVHDEFKGIELDLLRREHPKAKI
LVHPESPANVVAQADVVGSTSQLIAAAQQLDANEFIVATDNGILHKMRMAAPGKMFIEAPTAGNSATCKSCAHCPWMAMN
ALTNLAEVLETGRNEIHVDADIGRRAVTCINRMLDFAAQQKANVRPAADLAKESALFSGVGPA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=346, Percent_Identity=64.7398843930636, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 41439; Mature: 41308

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQTIKSVEFEKPNLTDPDAAAGGSCVAHAWAKVPPALTPDERQALKSRIRKLLKERNA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
VLVAHYYVDADLQDLAEETGGCVSDSLEMARFGRDHDAKTLVVAGVRFMGETAKILSPEK
EEEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCC
TILMPDLDATCSLDLGCPADDFSAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLKI
EEEECCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHH
VEHLHARGEKILWAPDKHLGSYIQQQTGADMLLWQGSCLVHDEFKGIELDLLRREHPKAK
HHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEHHCCCCCEE
ILVHPESPANVVAQADVVGSTSQLIAAAQQLDANEFIVATDNGILHKMRMAAPGKMFIEA
EEECCCCCCCCEEEHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEEEEC
PTAGNSATCKSCAHCPWMAMNALTNLAEVLETGRNEIHVDADIGRRAVTCINRMLDFAAQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
QKANVRPAADLAKESALFSGVGPA
HCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TPQTIKSVEFEKPNLTDPDAAAGGSCVAHAWAKVPPALTPDERQALKSRIRKLLKERNA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
VLVAHYYVDADLQDLAEETGGCVSDSLEMARFGRDHDAKTLVVAGVRFMGETAKILSPEK
EEEEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCC
TILMPDLDATCSLDLGCPADDFSAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLKI
EEEECCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHH
VEHLHARGEKILWAPDKHLGSYIQQQTGADMLLWQGSCLVHDEFKGIELDLLRREHPKAK
HHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEHHCCCCCEE
ILVHPESPANVVAQADVVGSTSQLIAAAQQLDANEFIVATDNGILHKMRMAAPGKMFIEA
EEECCCCCCCCEEEHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEEEEC
PTAGNSATCKSCAHCPWMAMNALTNLAEVLETGRNEIHVDADIGRRAVTCINRMLDFAAQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
QKANVRPAADLAKESALFSGVGPA
HCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA