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The map label for this gene is htpG

Identifier: 94311442

GI number: 94311442

Start: 2720365

End: 2722266

Strand: Reverse

Name: htpG

Synonym: Rmet_2506

Alternate gene names: 94311442

Gene position: 2722266-2720365 (Counterclockwise)

Preceding gene: 94311443

Following gene: 94311441

Centisome position: 69.3

GC content: 63.88

Gene sequence:

>1902_bases
ATGACCGCACCGCACGAAACGATGAGCTTCCAGGCGGAAGTGAAGCAGCTACTGCACCTGATGATCCACTCGCTGTACAG
CAACAAGGAGATCTTCCTGCGCGAGCTGGTATCGAATGCTTCCGACGCCACCGACAAGCTGCGCTTCGAGGCGATCGCGA
ATCCCGCGTTGCTCGAGAACGATGCCGACCTGGCGATCCGGATCGAAGCCGATCCCGCCGCCCGCACCCTGAAGATCACC
GACAACGGCATCGGCATGAGCCGTGACGAGGCGATCCGCAATCTCGGCACCATCGCGCGGTCGGGCACCAAGGAGTTCTT
CCAGCAGCTTTCCGGCGACCAGCAGAAGGACGCCGCGCTGATTGGCCAGTTTGGCGTGGGCTTCTACTCGGCATTCATCG
TGGCCGACAAGGTCACCGTGGAAACGCGTCGCGCGGGTCTTGCCGCCGACGAGGCCGTGCGCTGGGAAAGCGCCGGCGAC
GGCGAGTTCAGCATCGATGCGATCAACCGTGCCGAGCGCGGCAGCACGATCACGCTGCATCTGCGCGAGGGCGAGGACGA
TTTCCTGTCGTCGTACCGCCTGCAGAACATCATCCGCAAGTACTCGGACCACATTTCGCTGCCGATCCGGATGCCCAAGG
AGGAATGGGATGCCGAGGCGCAGCAGCAGAAGGTCACGGGCGAGTGGGAAAGCGTGAACCAGGCCAGCGCGCTCTGGACT
CGCAGCAAGTCGGATATCACGGACGAGCAATACCAGGCGTTCTATCAGCACATCGCGCACGATCACGAGGCGCCGCTGGC
CTGGACCCACAATCGCGTGGAAGGCCGCAGCGAGTACACGCAGCTGCTGTACATCCCGGCGCGCGCGCCGTTCGACCTGT
GGGACCGTAATCACAAGGCCGGCCTGAAGCTGTACGTGAAGCGCGTGTTCATCATGGATGACGCGGACCAGCTCCTGCCG
GCGTACCTACGCTGGGTCAAGGGCGTGGTCGATTCGGCGGACCTGCCGCTGAACGTGTCGCGTGAACTGCTGCAGGAGAG
CCGCGATGTGAAGGCGATCCGCGAGGGCTGCGCCAAGCGCGTGCTGTCGATGCTGGAAGCGATGGCCGATAGCGAAGACG
AAGCCGAACGCGCCAAGTACAAGACCTTCTGGGAACAGTTCGGTCAGGTGCTCAAGGAAGGCGTTGGCGAAGACCATGGC
AACGGCGAACGCATCGCAAAGCTGCTGCGCTTCGCGACCACGCATGGCGACACGGCTGAACAGTCGGTCTCGCTGGTCGA
CTACGTGGGCCGCATGAAGGAAGGTCAGGACAAGATCTACTACGTCACGGCCGATACCTGGGTGGCCGCGAAGTCGAGCC
CGCACCTCGAGGTGTTCCGCAAGAAGGGCATCGAAGTGGTGCTGTTGACCGACCGCGTTGACGAATGGCTGCTGTCCTAC
CTGCATGAATTCGACGGCAAGCAACTAGTGTCGGTGGCCCGTGGCGACCTGGACCTGGGCGCGCTGGCCGACGAAGCCGA
GAAGGCCGAGCAGGAGAAGGCCAGCGCCGACTGGAAGGAAGTGGTCGACCGCGCGAAGTCCGTGCTCGAAGGCAAGGCCA
AGGACGTACGCGTGACGCTGCGCCTGACGGATTCGGCATCGTGCCTGGTGTCCGACGATGGCGACATGAGCGGCTACCTG
CAGCGTCTGCTGAAGCAGGCTGGCCAGAAGGCGCCCGATGCCCAGCCGATCCTGGAGCTGAATCCGGAGCACGCGCTGGT
GAAGAAGCTGCGCGATCTGCCGGATGGCGAAGCCTTCGGCGACCGCGTGCGCGTGCTGTTCGACCAGGCGTTGCTGGCCG
AGGGCGGCATGCTCGACGATCCGGCTGCCTATGTGCAGCGGGTGAACCGACTGCTGGCCTGA

Upstream 100 bases:

>100_bases
AAAACCGGCTGCCGATCCCTATTTCCACACGCATCGATCCCGGTCCGGACGCACGGACCAGGGCAAATACGCGCCCGTTT
TCGTTTTCAAGAGGAGAACC

Downstream 100 bases:

>100_bases
TCGGTATCGTCGTTTCGGTATCGTCGTATGAAACGCCTGCCCTCTCACCCGACCTTTCTTCCCGCGCATGGGAAAGGGTA
TCGCGGGGGAGGGCAGGACT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPALLENDADLAIRIEADPAARTLKIT
DNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAALIGQFGVGFYSAFIVADKVTVETRRAGLAADEAVRWESAGD
GEFSIDAINRAERGSTITLHLREGEDDFLSSYRLQNIIRKYSDHISLPIRMPKEEWDAEAQQQKVTGEWESVNQASALWT
RSKSDITDEQYQAFYQHIAHDHEAPLAWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKAGLKLYVKRVFIMDDADQLLP
AYLRWVKGVVDSADLPLNVSRELLQESRDVKAIREGCAKRVLSMLEAMADSEDEAERAKYKTFWEQFGQVLKEGVGEDHG
NGERIAKLLRFATTHGDTAEQSVSLVDYVGRMKEGQDKIYYVTADTWVAAKSSPHLEVFRKKGIEVVLLTDRVDEWLLSY
LHEFDGKQLVSVARGDLDLGALADEAEKAEQEKASADWKEVVDRAKSVLEGKAKDVRVTLRLTDSASCLVSDDGDMSGYL
QRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPDGEAFGDRVRVLFDQALLAEGGMLDDPAAYVQRVNRLLA

Sequences:

>Translated_633_residues
MTAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPALLENDADLAIRIEADPAARTLKIT
DNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAALIGQFGVGFYSAFIVADKVTVETRRAGLAADEAVRWESAGD
GEFSIDAINRAERGSTITLHLREGEDDFLSSYRLQNIIRKYSDHISLPIRMPKEEWDAEAQQQKVTGEWESVNQASALWT
RSKSDITDEQYQAFYQHIAHDHEAPLAWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKAGLKLYVKRVFIMDDADQLLP
AYLRWVKGVVDSADLPLNVSRELLQESRDVKAIREGCAKRVLSMLEAMADSEDEAERAKYKTFWEQFGQVLKEGVGEDHG
NGERIAKLLRFATTHGDTAEQSVSLVDYVGRMKEGQDKIYYVTADTWVAAKSSPHLEVFRKKGIEVVLLTDRVDEWLLSY
LHEFDGKQLVSVARGDLDLGALADEAEKAEQEKASADWKEVVDRAKSVLEGKAKDVRVTLRLTDSASCLVSDDGDMSGYL
QRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPDGEAFGDRVRVLFDQALLAEGGMLDDPAAYVQRVNRLLA
>Mature_632_residues
TAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPALLENDADLAIRIEADPAARTLKITD
NGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAALIGQFGVGFYSAFIVADKVTVETRRAGLAADEAVRWESAGDG
EFSIDAINRAERGSTITLHLREGEDDFLSSYRLQNIIRKYSDHISLPIRMPKEEWDAEAQQQKVTGEWESVNQASALWTR
SKSDITDEQYQAFYQHIAHDHEAPLAWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKAGLKLYVKRVFIMDDADQLLPA
YLRWVKGVVDSADLPLNVSRELLQESRDVKAIREGCAKRVLSMLEAMADSEDEAERAKYKTFWEQFGQVLKEGVGEDHGN
GERIAKLLRFATTHGDTAEQSVSLVDYVGRMKEGQDKIYYVTADTWVAAKSSPHLEVFRKKGIEVVLLTDRVDEWLLSYL
HEFDGKQLVSVARGDLDLGALADEAEKAEQEKASADWKEVVDRAKSVLEGKAKDVRVTLRLTDSASCLVSDDGDMSGYLQ
RLLKQAGQKAPDAQPILELNPEHALVKKLRDLPDGEAFGDRVRVLFDQALLAEGGMLDDPAAYVQRVNRLLA

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=686, Percent_Identity=37.7551020408163, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI4507677, Length=691, Percent_Identity=37.7713458755427, Blast_Score=434, Evalue=1e-122,
Organism=Homo sapiens, GI155722983, Length=646, Percent_Identity=35.6037151702786, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=37.6811594202899, Blast_Score=282, Evalue=6e-76,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=37.43961352657, Blast_Score=280, Evalue=2e-75,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=59.2063492063492, Blast_Score=766, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=677, Percent_Identity=38.5524372230428, Blast_Score=475, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17542208, Length=679, Percent_Identity=37.4079528718704, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=649, Percent_Identity=32.9738058551618, Blast_Score=305, Evalue=5e-83,
Organism=Caenorhabditis elegans, GI115535167, Length=432, Percent_Identity=34.7222222222222, Blast_Score=245, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6323840, Length=682, Percent_Identity=37.8299120234604, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6325016, Length=418, Percent_Identity=37.0813397129187, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI17647529, Length=693, Percent_Identity=38.0952380952381, Blast_Score=471, Evalue=1e-133,
Organism=Drosophila melanogaster, GI21357739, Length=684, Percent_Identity=36.8421052631579, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24586016, Length=653, Percent_Identity=33.843797856049, Blast_Score=350, Evalue=1e-96,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_RALME (Q1LKE3)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_584652.1
- ProteinModelPortal:   Q1LKE3
- STRING:   Q1LKE3
- GeneID:   4039329
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_2506
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   Q1LKE3
- ProtClustDB:   PRK05218
- BioCyc:   RMET266264:RMET_2506-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71068; Mature: 70936

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPALLEN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCC
DADLAIRIEADPAARTLKITDNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAAL
CCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
IGQFGVGFYSAFIVADKVTVETRRAGLAADEAVRWESAGDGEFSIDAINRAERGSTITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEHHHHHHCCCCCEEEEE
LREGEDDFLSSYRLQNIIRKYSDHISLPIRMPKEEWDAEAQQQKVTGEWESVNQASALWT
EECCCHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHCCHHHHHHCCCCHHHHHHHHHHHH
RSKSDITDEQYQAFYQHIAHDHEAPLAWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKA
CCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHCCCCCC
GLKLYVKRVFIMDDADQLLPAYLRWVKGVVDSADLPLNVSRELLQESRDVKAIREGCAKR
HHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLSMLEAMADSEDEAERAKYKTFWEQFGQVLKEGVGEDHGNGERIAKLLRFATTHGDTAE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHH
QSVSLVDYVGRMKEGQDKIYYVTADTWVAAKSSPHLEVFRKKGIEVVLLTDRVDEWLLSY
HHHHHHHHHHHHCCCCCEEEEEEECCEEECCCCCHHHHHHHCCCEEEEECCHHHHHHHHH
LHEFDGKQLVSVARGDLDLGALADEAEKAEQEKASADWKEVVDRAKSVLEGKAKDVRVTL
HHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEE
RLTDSASCLVSDDGDMSGYLQRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPDGEAFG
EEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCHHH
DRVRVLFDQALLAEGGMLDDPAAYVQRVNRLLA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDATDKLRFEAIANPALLEN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCC
DADLAIRIEADPAARTLKITDNGIGMSRDEAIRNLGTIARSGTKEFFQQLSGDQQKDAAL
CCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
IGQFGVGFYSAFIVADKVTVETRRAGLAADEAVRWESAGDGEFSIDAINRAERGSTITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEHHHHHHCCCCCEEEEE
LREGEDDFLSSYRLQNIIRKYSDHISLPIRMPKEEWDAEAQQQKVTGEWESVNQASALWT
EECCCHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHCCHHHHHHCCCCHHHHHHHHHHHH
RSKSDITDEQYQAFYQHIAHDHEAPLAWTHNRVEGRSEYTQLLYIPARAPFDLWDRNHKA
CCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHCCCCCC
GLKLYVKRVFIMDDADQLLPAYLRWVKGVVDSADLPLNVSRELLQESRDVKAIREGCAKR
HHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VLSMLEAMADSEDEAERAKYKTFWEQFGQVLKEGVGEDHGNGERIAKLLRFATTHGDTAE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHH
QSVSLVDYVGRMKEGQDKIYYVTADTWVAAKSSPHLEVFRKKGIEVVLLTDRVDEWLLSY
HHHHHHHHHHHHCCCCCEEEEEEECCEEECCCCCHHHHHHHCCCEEEEECCHHHHHHHHH
LHEFDGKQLVSVARGDLDLGALADEAEKAEQEKASADWKEVVDRAKSVLEGKAKDVRVTL
HHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEE
RLTDSASCLVSDDGDMSGYLQRLLKQAGQKAPDAQPILELNPEHALVKKLRDLPDGEAFG
EEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCHHH
DRVRVLFDQALLAEGGMLDDPAAYVQRVNRLLA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA