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The map label for this gene is ydfD [H]

Identifier: 94311443

GI number: 94311443

Start: 2722367

End: 2723914

Strand: Reverse

Name: ydfD [H]

Synonym: Rmet_2507

Alternate gene names: 94311443

Gene position: 2723914-2722367 (Counterclockwise)

Preceding gene: 94311453

Following gene: 94311442

Centisome position: 69.34

GC content: 67.7

Gene sequence:

>1548_bases
ATGGAAGGTAGCCAGAAGGATAGCCGGGGGGATCTTGGCAGTGCCGCAGGCGGCACACGGCCGTTGCGGCTCGTGATGCC
GGCGACGGGGCTCGAGCAGCTTCCGGACCCGATTCCGTCGGCCCAGATGACGCTGGTGGAGCAGTTGACCGAGTGGGCGC
GGCTGCGTATCGACGAACGGGTGTTCCGGGCTGGCATGCGTATGCCGTCGATCCGTCAGTTGGCGACCGAGAAGAGCATT
TCGCGTTTTACCGTGGTGGAGGCCTATGAGCGGCTGGTGGCGCTGGGCTACCTCGAGTCGCGCCGCGGCTCGGGCTTCTA
CGTCCGAGAGCGCACGCCGCTCGCGTCCACCGTGGCGCCACCGGCCACTCCCGCGATCCGCAACGTCGATGTCACCTGGC
TGCTGCGCAGCATGTTCCATTCGGCCGAGAGCCACAAGGCGCCCGGCTGGGGCTTCCTGCCCAACGAATGGCTGGACGGG
GAGCTCCTGTCGGGTGCGCTGCGCAGCCTGGGCCGTCAGCCCGGCAGCCATTTCCTGGTCAGCGGCACGCCGCAGGGTTT
TCTGCCGCTGCGGCAGCAACTGCGCACGCGGCTCGAAGAGCTGGAGATCGGCGTCACGCCGGACCAGATCGTGATGACTT
CCGGCATCACGCAGGCGTTCGACCTGATCGCGCGCCAGTTCCTGCAGCCGGGCGACACGGTGGTGGTAGGCGACCCGGCC
TGGTTCGTGATGTTCGCCCGCTTCGCCACGCAGGGCGCCAACGTGATCGGCGTGCCCTATACCGTGGAGGGCCCCGACGT
GGAGGCGCTGGAGCGGATCGTCCAGGCCCACCGGCCGAAGCTGCTGGTGGTCAACTCCGTGCTGCACAACCCGACCGGGA
CGTCGCTGTCCGCCGCCCGCGCTTTTCGGCTGCTGCAACTGGCCGAACAGTACGATTTCACGATCGTCGAGGATGACATC
TACAGCGATCTCTGCCCTCCGGGCCACGCCGCCACCCGGCTGGCCAGCCTGGACCAGCTCAAGCGCGTGATCTACCTGGG
CAGCTTCTCCAAGACGCTGGCCGCCAACCTGCGCGTGGGCTTTATCGCCGCCAGTCCGGACCTGGCCGTGACCTTGACCG
ACAGCAAGCTCGTGACCGGCATGGCCTCGCCCGAAGTCAACGAACGCGTGGTCTACAAGGTGCTGACGGAAGGGCACTAC
CGCAAGCACGTGGAGCGCGTGCGCGGCCGGCTGGACCGGGCGCGCGACGAGACACGCGAGCAGCTCGAGCGGTTGGGTTT
GCGCATCTTCCCGGGCAATCATGCGGGTATCTACCTGTGGGCCGATACCGGCGTGGACACCAACGTGATCGCCACGGCCG
GGCACGAGGAAGGTTATCTGTTCGCGCCGGGCAGCCTGTTCTCGCCATCGCAGATGCCGTCCACGTGGACGCGCTTCAAC
GTGGCCAGCAGCAGCGATCCGGGCATGCTCCGGTTCCTGGCCGGCCAGATGGACCGCTTGTCCGGCCAATCGGGCCTGTC
TGGCCTGCCCGTCAACGCCGGGGCTTGA

Upstream 100 bases:

>100_bases
CGATGGCAAGTGTCATGGTCGGTTGATGTTAGTCAAGCTCGTCGGTACAGTACCGATACAGTTGAGCAGATCGTCTTCAG
TACAGTTGCGGGAGCGCCAC

Downstream 100 bases:

>100_bases
AAAACCGGCTGCCGATCCCTATTTCCACACGCATCGATCCCGGTCCGGACGCACGGACCAGGGCAAATACGCGCCCGTTT
TCGTTTTCAAGAGGAGAACC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MEGSQKDSRGDLGSAAGGTRPLRLVMPATGLEQLPDPIPSAQMTLVEQLTEWARLRIDERVFRAGMRMPSIRQLATEKSI
SRFTVVEAYERLVALGYLESRRGSGFYVRERTPLASTVAPPATPAIRNVDVTWLLRSMFHSAESHKAPGWGFLPNEWLDG
ELLSGALRSLGRQPGSHFLVSGTPQGFLPLRQQLRTRLEELEIGVTPDQIVMTSGITQAFDLIARQFLQPGDTVVVGDPA
WFVMFARFATQGANVIGVPYTVEGPDVEALERIVQAHRPKLLVVNSVLHNPTGTSLSAARAFRLLQLAEQYDFTIVEDDI
YSDLCPPGHAATRLASLDQLKRVIYLGSFSKTLAANLRVGFIAASPDLAVTLTDSKLVTGMASPEVNERVVYKVLTEGHY
RKHVERVRGRLDRARDETREQLERLGLRIFPGNHAGIYLWADTGVDTNVIATAGHEEGYLFAPGSLFSPSQMPSTWTRFN
VASSSDPGMLRFLAGQMDRLSGQSGLSGLPVNAGA

Sequences:

>Translated_515_residues
MEGSQKDSRGDLGSAAGGTRPLRLVMPATGLEQLPDPIPSAQMTLVEQLTEWARLRIDERVFRAGMRMPSIRQLATEKSI
SRFTVVEAYERLVALGYLESRRGSGFYVRERTPLASTVAPPATPAIRNVDVTWLLRSMFHSAESHKAPGWGFLPNEWLDG
ELLSGALRSLGRQPGSHFLVSGTPQGFLPLRQQLRTRLEELEIGVTPDQIVMTSGITQAFDLIARQFLQPGDTVVVGDPA
WFVMFARFATQGANVIGVPYTVEGPDVEALERIVQAHRPKLLVVNSVLHNPTGTSLSAARAFRLLQLAEQYDFTIVEDDI
YSDLCPPGHAATRLASLDQLKRVIYLGSFSKTLAANLRVGFIAASPDLAVTLTDSKLVTGMASPEVNERVVYKVLTEGHY
RKHVERVRGRLDRARDETREQLERLGLRIFPGNHAGIYLWADTGVDTNVIATAGHEEGYLFAPGSLFSPSQMPSTWTRFN
VASSSDPGMLRFLAGQMDRLSGQSGLSGLPVNAGA
>Mature_515_residues
MEGSQKDSRGDLGSAAGGTRPLRLVMPATGLEQLPDPIPSAQMTLVEQLTEWARLRIDERVFRAGMRMPSIRQLATEKSI
SRFTVVEAYERLVALGYLESRRGSGFYVRERTPLASTVAPPATPAIRNVDVTWLLRSMFHSAESHKAPGWGFLPNEWLDG
ELLSGALRSLGRQPGSHFLVSGTPQGFLPLRQQLRTRLEELEIGVTPDQIVMTSGITQAFDLIARQFLQPGDTVVVGDPA
WFVMFARFATQGANVIGVPYTVEGPDVEALERIVQAHRPKLLVVNSVLHNPTGTSLSAARAFRLLQLAEQYDFTIVEDDI
YSDLCPPGHAATRLASLDQLKRVIYLGSFSKTLAANLRVGFIAASPDLAVTLTDSKLVTGMASPEVNERVVYKVLTEGHY
RKHVERVRGRLDRARDETREQLERLGLRIFPGNHAGIYLWADTGVDTNVIATAGHEEGYLFAPGSLFSPSQMPSTWTRFN
VASSSDPGMLRFLAGQMDRLSGQSGLSGLPVNAGA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=334, Percent_Identity=27.2455089820359, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI33469970, Length=334, Percent_Identity=27.2455089820359, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1787710, Length=454, Percent_Identity=27.0925110132159, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1790797, Length=458, Percent_Identity=28.3842794759825, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321236, Length=185, Percent_Identity=31.3513513513514, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56445; Mature: 56445

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGSQKDSRGDLGSAAGGTRPLRLVMPATGLEQLPDPIPSAQMTLVEQLTEWARLRIDER
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VFRAGMRMPSIRQLATEKSISRFTVVEAYERLVALGYLESRRGSGFYVRERTPLASTVAP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCC
PATPAIRNVDVTWLLRSMFHSAESHKAPGWGFLPNEWLDGELLSGALRSLGRQPGSHFLV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
SGTPQGFLPLRQQLRTRLEELEIGVTPDQIVMTSGITQAFDLIARQFLQPGDTVVVGDPA
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEECCHH
WFVMFARFATQGANVIGVPYTVEGPDVEALERIVQAHRPKLLVVNSVLHNPTGTSLSAAR
HHHHHHHHHHCCCCEEECCEEECCCCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCHHHHH
AFRLLQLAEQYDFTIVEDDIYSDLCPPGHAATRLASLDQLKRVIYLGSFSKTLAANLRVG
HHHHHHHHHHCCCEEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEE
FIAASPDLAVTLTDSKLVTGMASPEVNERVVYKVLTEGHYRKHVERVRGRLDRARDETRE
EEEECCCEEEEEECCHHEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QLERLGLRIFPGNHAGIYLWADTGVDTNVIATAGHEEGYLFAPGSLFSPSQMPSTWTRFN
HHHHCCEEEECCCCCEEEEEECCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHEEE
VASSSDPGMLRFLAGQMDRLSGQSGLSGLPVNAGA
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEGSQKDSRGDLGSAAGGTRPLRLVMPATGLEQLPDPIPSAQMTLVEQLTEWARLRIDER
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VFRAGMRMPSIRQLATEKSISRFTVVEAYERLVALGYLESRRGSGFYVRERTPLASTVAP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCC
PATPAIRNVDVTWLLRSMFHSAESHKAPGWGFLPNEWLDGELLSGALRSLGRQPGSHFLV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
SGTPQGFLPLRQQLRTRLEELEIGVTPDQIVMTSGITQAFDLIARQFLQPGDTVVVGDPA
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEECCHH
WFVMFARFATQGANVIGVPYTVEGPDVEALERIVQAHRPKLLVVNSVLHNPTGTSLSAAR
HHHHHHHHHHCCCCEEECCEEECCCCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCHHHHH
AFRLLQLAEQYDFTIVEDDIYSDLCPPGHAATRLASLDQLKRVIYLGSFSKTLAANLRVG
HHHHHHHHHHCCCEEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEE
FIAASPDLAVTLTDSKLVTGMASPEVNERVVYKVLTEGHYRKHVERVRGRLDRARDETRE
EEEECCCEEEEEECCHHEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QLERLGLRIFPGNHAGIYLWADTGVDTNVIATAGHEEGYLFAPGSLFSPSQMPSTWTRFN
HHHHCCEEEECCCCCEEEEEECCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHEEE
VASSSDPGMLRFLAGQMDRLSGQSGLSGLPVNAGA
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]