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The map label for this gene is hflX [H]

Identifier: 94311038

GI number: 94311038

Start: 2280889

End: 2282124

Strand: Reverse

Name: hflX [H]

Synonym: Rmet_2100

Alternate gene names: 94311038

Gene position: 2282124-2280889 (Counterclockwise)

Preceding gene: 94311039

Following gene: 94311037

Centisome position: 58.1

GC content: 64.24

Gene sequence:

>1236_bases
TTGCAACCCAGAGCTACCTCCCAGACCGAACCGACCCGTGCCATCCTGGTTGGCGTCGACTTCGGCAAGCATGACTTCCA
GGAAAGCCTTTCCGAACTGGCGCTGTTGACGACCACGGCCGGCTCGGTGCCTGTGCACACGCTGACCGGCAAGCGTTCGC
GCCCCGATCCGGCACTCTTCATCGGATCCGGCAAGGCCGAGGAACTGCGGCAGGCCGCTGACGCGCTGGATGCCGATGTG
GTGGTGTTCAACCACGCCTTGAGTCCTGCCCAGCAGCGCAACCTGGAGCGATTCCTGGGGCGTCATGTGATCGACCGAAC
CGGTCTGATCCTGGATATCTTTGGTCAGCGTGCACAGAGCCACGTCGGCAAGGTGCAGGTGGAACTGGCGCAGGTGCAGT
ACCAGGCGTCGCGCCTGGTTCGCGCGTGGAGCCACCTGGAACGGCAGAAGGGTGGTATCGGGATGCGCGGCGGCCCTGGC
GAGCGACAGCTCGAACTGGATCGGCGGATGCTCGATGATCGAGCCAAACGACTCAAGTCCGATCTGGCGCGCCTGCAGCG
CCAGCACCATACGCAGCGCCGCGCCCGGGCCCGTAATGACACGCTCAGTATCTCGCTGGTCGGATATACGAACGCCGGCA
AGTCGACGCTGTTCAATGCGCTGACCAAGGCGCGGGCCTATGCGGCCGATCAGCTTTTTGCCACGCTCGATACGACCTCG
CGCCGCCTGTTTCTCGACGGATTCGGCAATGTGGTGCTGTCCGACACCGTCGGGTTCATCCGGGATCTGCCGACACAACT
CGTGGCGGCGTTCCGCGCCACGCTCGACGAGACCGTGCATGCCGACCTGCTCCTGCATGTGGTCGATGCATCGAGTCCAG
TGCGCCACGAGCAGATCGAACAGGTCAATCGTGTGCTCGCCGAGATCGACGCCTCGGACATTCCGCAGATCGTGGTCATG
AACAAGATCGATGCGGCACCAGAGCTGCTCGAACTCGGCCCCCGTGTCGAGCGAGACGAAGACGGTGTTCCAACGAAAGT
GTTTGTCTCCGCCCGGGATGGCCTGGGGCTGGATGGCCTCCGCGAGGCCATCGTCGCGATGGCCCAATGGCTGTCGTCGC
GGCCGGAGGCCCCGGCCCCCTATGATCCAAGGCTGGAAGGGCTGCAGCCCGCCCAGGATGGGGAGCCGTGGGACGTCGAT
GACGAACCAGATACCCGCCAGCAAGGTGCCAATTGA

Upstream 100 bases:

>100_bases
ACCTGTCCCGAGCCTTACGGCGTCCGGGGGCGGCAGGCTGCGCCAACGCGGCCAGATTTTGTCTTAACAACGATCCCTTC
GGCGCACTGCGTCCATCCGC

Downstream 100 bases:

>100_bases
TCGTTTTTGAACGAGAATCCCCGCCCGATTGGGGATTCTGGGCAAAAGTGATCAAGATGGCTGCTAGAATCCCTCTGATC
CAAACTTCCCGGACCCGTGC

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MQPRATSQTEPTRAILVGVDFGKHDFQESLSELALLTTTAGSVPVHTLTGKRSRPDPALFIGSGKAEELRQAADALDADV
VVFNHALSPAQQRNLERFLGRHVIDRTGLILDIFGQRAQSHVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPG
ERQLELDRRMLDDRAKRLKSDLARLQRQHHTQRRARARNDTLSISLVGYTNAGKSTLFNALTKARAYAADQLFATLDTTS
RRLFLDGFGNVVLSDTVGFIRDLPTQLVAAFRATLDETVHADLLLHVVDASSPVRHEQIEQVNRVLAEIDASDIPQIVVM
NKIDAAPELLELGPRVERDEDGVPTKVFVSARDGLGLDGLREAIVAMAQWLSSRPEAPAPYDPRLEGLQPAQDGEPWDVD
DEPDTRQQGAN

Sequences:

>Translated_411_residues
MQPRATSQTEPTRAILVGVDFGKHDFQESLSELALLTTTAGSVPVHTLTGKRSRPDPALFIGSGKAEELRQAADALDADV
VVFNHALSPAQQRNLERFLGRHVIDRTGLILDIFGQRAQSHVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPG
ERQLELDRRMLDDRAKRLKSDLARLQRQHHTQRRARARNDTLSISLVGYTNAGKSTLFNALTKARAYAADQLFATLDTTS
RRLFLDGFGNVVLSDTVGFIRDLPTQLVAAFRATLDETVHADLLLHVVDASSPVRHEQIEQVNRVLAEIDASDIPQIVVM
NKIDAAPELLELGPRVERDEDGVPTKVFVSARDGLGLDGLREAIVAMAQWLSSRPEAPAPYDPRLEGLQPAQDGEPWDVD
DEPDTRQQGAN
>Mature_411_residues
MQPRATSQTEPTRAILVGVDFGKHDFQESLSELALLTTTAGSVPVHTLTGKRSRPDPALFIGSGKAEELRQAADALDADV
VVFNHALSPAQQRNLERFLGRHVIDRTGLILDIFGQRAQSHVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPG
ERQLELDRRMLDDRAKRLKSDLARLQRQHHTQRRARARNDTLSISLVGYTNAGKSTLFNALTKARAYAADQLFATLDTTS
RRLFLDGFGNVVLSDTVGFIRDLPTQLVAAFRATLDETVHADLLLHVVDASSPVRHEQIEQVNRVLAEIDASDIPQIVVM
NKIDAAPELLELGPRVERDEDGVPTKVFVSARDGLGLDGLREAIVAMAQWLSSRPEAPAPYDPRLEGLQPAQDGEPWDVD
DEPDTRQQGAN

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=236, Percent_Identity=37.2881355932203, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI310133116, Length=232, Percent_Identity=37.9310344827586, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI310124269, Length=211, Percent_Identity=38.3886255924171, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI310124267, Length=211, Percent_Identity=38.3886255924171, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI310124171, Length=211, Percent_Identity=38.3886255924171, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI310124169, Length=211, Percent_Identity=38.3886255924171, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1790615, Length=352, Percent_Identity=55.1136363636364, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17561038, Length=353, Percent_Identity=29.4617563739377, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24650079, Length=301, Percent_Identity=33.8870431893688, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 45332; Mature: 45332

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPRATSQTEPTRAILVGVDFGKHDFQESLSELALLTTTAGSVPVHTLTGKRSRPDPALF
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEE
IGSGKAEELRQAADALDADVVVFNHALSPAQQRNLERFLGRHVIDRTGLILDIFGQRAQS
ECCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPGERQLELDRRMLDDRAKRLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DLARLQRQHHTQRRARARNDTLSISLVGYTNAGKSTLFNALTKARAYAADQLFATLDTTS
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RRLFLDGFGNVVLSDTVGFIRDLPTQLVAAFRATLDETVHADLLLHVVDASSPVRHEQIE
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QVNRVLAEIDASDIPQIVVMNKIDAAPELLELGPRVERDEDGVPTKVFVSARDGLGLDGL
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHH
REAIVAMAQWLSSRPEAPAPYDPRLEGLQPAQDGEPWDVDDEPDTRQQGAN
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MQPRATSQTEPTRAILVGVDFGKHDFQESLSELALLTTTAGSVPVHTLTGKRSRPDPALF
CCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEE
IGSGKAEELRQAADALDADVVVFNHALSPAQQRNLERFLGRHVIDRTGLILDIFGQRAQS
ECCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVGKVQVELAQVQYQASRLVRAWSHLERQKGGIGMRGGPGERQLELDRRMLDDRAKRLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DLARLQRQHHTQRRARARNDTLSISLVGYTNAGKSTLFNALTKARAYAADQLFATLDTTS
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RRLFLDGFGNVVLSDTVGFIRDLPTQLVAAFRATLDETVHADLLLHVVDASSPVRHEQIE
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QVNRVLAEIDASDIPQIVVMNKIDAAPELLELGPRVERDEDGVPTKVFVSARDGLGLDGL
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHH
REAIVAMAQWLSSRPEAPAPYDPRLEGLQPAQDGEPWDVDDEPDTRQQGAN
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]