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The map label for this gene is hflK [H]

Identifier: 94311037

GI number: 94311037

Start: 2279440

End: 2280783

Strand: Reverse

Name: hflK [H]

Synonym: Rmet_2099

Alternate gene names: 94311037

Gene position: 2280783-2279440 (Counterclockwise)

Preceding gene: 94311038

Following gene: 94311036

Centisome position: 58.06

GC content: 62.72

Gene sequence:

>1344_bases
ATGCCCCTGTTCCCTCGGAATCCTGACCCGCACATCGTGCCAGGCAGCCGCGCCCTGCGGTTTGCGCGCTGGCCGCGCCT
GCGCGCCATCTTCTCGCTGAACGACCCCCGCTGGGGCCGCAACGGACAGGACGATGAAGACAAGGACAATAGCCGCCAGC
AAAACCAGCGCCCGCAGGATGGCCCGCCCGATCTCGATGAGCTCTGGCGCGACTTCAATCGCCGCCTGAACGGCCTGCTG
GGCCGCAAGGACAACGGCGGTGGTGGCCAGGGTTTCGGCAGTGGCCCGCGCCCGTCAGGCAAGGGTTCTAATGTCGGCAT
CGGCGTGATCATCGCCGCCGTGATCGGTATCTGGCTGGCCAGCGGTTTCTTCATGGTGCAGGAAGGGCAGACCGCTGTGA
TCCTGCAGTTCGGCAAGTTCAAGTACTCCACCGGTCCCGGTATCAACTGGCGTATGCCATGGCCGATCCAGTCGGCCGAA
GTGGTAAACCTGTCGGCTGTGCGTTCGGTGGAGGTCGGTCGTGCCACGTCGATCAAGGACAGCAACCTGAAGGACTCGTC
GATGCTGACGCAGGACGAGAACATCATCGACGTCCGGTTCACGGTGCAATACGACATCCAGGACGCCAGCGAATTCCTGT
TCTTCAACAAGACCGACCGCGGTGGCGACGAAGAACTCGTGACGCAGGCCGCGGAAACGTCAGTGCGTGAGATCGTCGGC
CGCAACAAGATGGATGCGGTGCTCTACGAGAATCGCGAGCAGATTGCGCAATCGCTGGCCAAGTCGATTCAATCGATCCT
CACGGCCTACAAGACGGGTATTCGTGTGATTTCCGTCAACGTTCAGAGCGTGCAGCCGCCCGAGCAGGTGCAGGCCGCAT
TCGACGACGTCAACAAGGCGAGCCAGGATCGCGAGCGCGCGATCAGCGAAGGCCAGGCCTATGCGAACGACATCATTCCG
CGCGCGAAGGGCACGGCGGCTCGCCTGAAGGAAGAATCGGAGGCCTACCGTTCCCGCGTGGTGGCACAGGCCGAAGGTGA
CGCAGCGCGCTTCCGCTCGGTGCAGTCCGAGTATGCCAAGGCACCGCAGGTCACGCGTGACCGTATTTATCTGGAGACCA
TGCAGCAGATCTACGCCAATTCGAGCAAGATTCTTGTCGATGCCAAGTCGGGCAATAACCTGCTGTATCTGCCGCTGGAC
AAGCTGATGACACAGGTGCCGGGCTCGTCGGCCGCACCGTCCTCGGCAGCGCCGGGCACGAATGCGCCGGCGGTACCGGA
TGCGACCACGCCGGATATCCGGTCACGTGAGTCGATGCGCAACCGCGACCGCGACATTCGCTAA

Upstream 100 bases:

>100_bases
TTTGAACGAGAATCCCCGCCCGATTGGGGATTCTGGGCAAAAGTGATCAAGATGGCTGCTAGAATCCCTCTGATCCAAAC
TTCCCGGACCCGTGCTCTTC

Downstream 100 bases:

>100_bases
GGAGACCCGTCATGAATCGACTGATTTCCTTTGTCATTGGCCTGTTTATCCTGCTGGCCGTTGCTTCGTCGATGCTGTTC
GTGGTCGACCAGCGCCAGTA

Product: modulator for HflB protease specific for phage lambda cII repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPLFPRNPDPHIVPGSRALRFARWPRLRAIFSLNDPRWGRNGQDDEDKDNSRQQNQRPQDGPPDLDELWRDFNRRLNGLL
GRKDNGGGGQGFGSGPRPSGKGSNVGIGVIIAAVIGIWLASGFFMVQEGQTAVILQFGKFKYSTGPGINWRMPWPIQSAE
VVNLSAVRSVEVGRATSIKDSNLKDSSMLTQDENIIDVRFTVQYDIQDASEFLFFNKTDRGGDEELVTQAAETSVREIVG
RNKMDAVLYENREQIAQSLAKSIQSILTAYKTGIRVISVNVQSVQPPEQVQAAFDDVNKASQDRERAISEGQAYANDIIP
RAKGTAARLKEESEAYRSRVVAQAEGDAARFRSVQSEYAKAPQVTRDRIYLETMQQIYANSSKILVDAKSGNNLLYLPLD
KLMTQVPGSSAAPSSAAPGTNAPAVPDATTPDIRSRESMRNRDRDIR

Sequences:

>Translated_447_residues
MPLFPRNPDPHIVPGSRALRFARWPRLRAIFSLNDPRWGRNGQDDEDKDNSRQQNQRPQDGPPDLDELWRDFNRRLNGLL
GRKDNGGGGQGFGSGPRPSGKGSNVGIGVIIAAVIGIWLASGFFMVQEGQTAVILQFGKFKYSTGPGINWRMPWPIQSAE
VVNLSAVRSVEVGRATSIKDSNLKDSSMLTQDENIIDVRFTVQYDIQDASEFLFFNKTDRGGDEELVTQAAETSVREIVG
RNKMDAVLYENREQIAQSLAKSIQSILTAYKTGIRVISVNVQSVQPPEQVQAAFDDVNKASQDRERAISEGQAYANDIIP
RAKGTAARLKEESEAYRSRVVAQAEGDAARFRSVQSEYAKAPQVTRDRIYLETMQQIYANSSKILVDAKSGNNLLYLPLD
KLMTQVPGSSAAPSSAAPGTNAPAVPDATTPDIRSRESMRNRDRDIR
>Mature_446_residues
PLFPRNPDPHIVPGSRALRFARWPRLRAIFSLNDPRWGRNGQDDEDKDNSRQQNQRPQDGPPDLDELWRDFNRRLNGLLG
RKDNGGGGQGFGSGPRPSGKGSNVGIGVIIAAVIGIWLASGFFMVQEGQTAVILQFGKFKYSTGPGINWRMPWPIQSAEV
VNLSAVRSVEVGRATSIKDSNLKDSSMLTQDENIIDVRFTVQYDIQDASEFLFFNKTDRGGDEELVTQAAETSVREIVGR
NKMDAVLYENREQIAQSLAKSIQSILTAYKTGIRVISVNVQSVQPPEQVQAAFDDVNKASQDRERAISEGQAYANDIIPR
AKGTAARLKEESEAYRSRVVAQAEGDAARFRSVQSEYAKAPQVTRDRIYLETMQQIYANSSKILVDAKSGNNLLYLPLDK
LMTQVPGSSAAPSSAAPGTNAPAVPDATTPDIRSRESMRNRDRDIR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=396, Percent_Identity=34.8484848484849, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 49412; Mature: 49281

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFPRNPDPHIVPGSRALRFARWPRLRAIFSLNDPRWGRNGQDDEDKDNSRQQNQRPQD
CCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCC
GPPDLDELWRDFNRRLNGLLGRKDNGGGGQGFGSGPRPSGKGSNVGIGVIIAAVIGIWLA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SGFFMVQEGQTAVILQFGKFKYSTGPGINWRMPWPIQSAEVVNLSAVRSVEVGRATSIKD
CCEEEEECCCEEEEEEECCEEECCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCC
SNLKDSSMLTQDENIIDVRFTVQYDIQDASEFLFFNKTDRGGDEELVTQAAETSVREIVG
CCCCCCHHCCCCCCEEEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHC
RNKMDAVLYENREQIAQSLAKSIQSILTAYKTGIRVISVNVQSVQPPEQVQAAFDDVNKA
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHH
SQDRERAISEGQAYANDIIPRAKGTAARLKEESEAYRSRVVAQAEGDAARFRSVQSEYAK
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
APQVTRDRIYLETMQQIYANSSKILVDAKSGNNLLYLPLDKLMTQVPGSSAAPSSAAPGT
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCCCCCCC
NAPAVPDATTPDIRSRESMRNRDRDIR
CCCCCCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PLFPRNPDPHIVPGSRALRFARWPRLRAIFSLNDPRWGRNGQDDEDKDNSRQQNQRPQD
CCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCC
GPPDLDELWRDFNRRLNGLLGRKDNGGGGQGFGSGPRPSGKGSNVGIGVIIAAVIGIWLA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SGFFMVQEGQTAVILQFGKFKYSTGPGINWRMPWPIQSAEVVNLSAVRSVEVGRATSIKD
CCEEEEECCCEEEEEEECCEEECCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCC
SNLKDSSMLTQDENIIDVRFTVQYDIQDASEFLFFNKTDRGGDEELVTQAAETSVREIVG
CCCCCCHHCCCCCCEEEEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHC
RNKMDAVLYENREQIAQSLAKSIQSILTAYKTGIRVISVNVQSVQPPEQVQAAFDDVNKA
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHH
SQDRERAISEGQAYANDIIPRAKGTAARLKEESEAYRSRVVAQAEGDAARFRSVQSEYAK
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
APQVTRDRIYLETMQQIYANSSKILVDAKSGNNLLYLPLDKLMTQVPGSSAAPSSAAPGT
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHCCCCCCCCCCCCCCC
NAPAVPDATTPDIRSRESMRNRDRDIR
CCCCCCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]