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The map label for this gene is hflC [H]

Identifier: 94311036

GI number: 94311036

Start: 2278526

End: 2279428

Strand: Reverse

Name: hflC [H]

Synonym: Rmet_2098

Alternate gene names: 94311036

Gene position: 2279428-2278526 (Counterclockwise)

Preceding gene: 94311037

Following gene: 94311035

Centisome position: 58.03

GC content: 61.24

Gene sequence:

>903_bases
ATGAATCGACTGATTTCCTTTGTCATTGGCCTGTTTATCCTGCTGGCCGTTGCTTCGTCGATGCTGTTCGTGGTCGACCA
GCGCCAGTACGCCGTCGTCTTCGCTTTCGGCGAAATCAAGCAGGTCGTGCGTGAGCCCGGTCTGCATTTCAAGCTGCCGC
CGCCGTTGCAGAACGTAGTGTTCATGGATCGTCGTCTGCAGACGATCGATGTCGCAGCCAACGAGCGTTTCCTGACCGCC
GAGAAGAAATCGATGGTGGTGGACTGGTTCGTGAAGTGGCGCATCACCGATCCGCGCAAATTCTTCGTGGCGTTTGGTGG
CAACCTGCGCGGCGCGCAGGACCGCATGACGCAGCGTATCGATGCTGTGGCGCGTGAGGAGTTCGGCAAGCGCACCGTGG
CGGATGTGGTGGCGGGCCAGCGCGAGCAGGTCATGCAGAACATCCGGGTTGGTATGGCCGAGTACGCGCAGTCGGTGGGT
GTCGAGATCATCGATGTGCGCCTGAAGCGTGTGGATCTGCTGCCGGCCATCAGCGAGTCGGTCTATCGACGCATGGAGGC
CGAGCGCAAGCGCGTGGCCAACGAACTGCGTTCGACTGGCGCCGCGGAAGGTGAGAAAATCCGGGCCGATGCTGATCGCC
AGCGTGAGGTGGTGCTGGCCGAGGCTTATCGTGATGCGCAGGTGGTCAAGGGTGAGGGCGATGCCAAGGCTTCGCAGATC
TATGCCGATGCATTCGGCAAGGATCCGAGCTTCGCCCAGTTCTGGCGCAGCATGGAGGCCTACCGCAACACGTTCCGCGA
CAAGGGCAACGTGATGGTGCTGGAGCCCAATTCGGACTTCTTCCGCTATATGCGTTCGCCGGGTGGCAACACCGCACCGG
CCCCGTCAGGTGGCAAGAAGTAG

Upstream 100 bases:

>100_bases
GCACGAATGCGCCGGCGGTACCGGATGCGACCACGCCGGATATCCGGTCACGTGAGTCGATGCGCAACCGCGACCGCGAC
ATTCGCTAAGGAGACCCGTC

Downstream 100 bases:

>100_bases
CGTGGATGGCGCACCAGGCGCCTGATCGCGTGATTCGACAGAACCCCGGATCTTCCGGGGTTTTGTCCGGCTGGAGGGCA
TGAACCTTTCCCGCCTGTGT

Product: modulator for HflB protease specific for phage lambda cII repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNRLISFVIGLFILLAVASSMLFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVVFMDRRLQTIDVAANERFLTA
EKKSMVVDWFVKWRITDPRKFFVAFGGNLRGAQDRMTQRIDAVAREEFGKRTVADVVAGQREQVMQNIRVGMAEYAQSVG
VEIIDVRLKRVDLLPAISESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVVKGEGDAKASQI
YADAFGKDPSFAQFWRSMEAYRNTFRDKGNVMVLEPNSDFFRYMRSPGGNTAPAPSGGKK

Sequences:

>Translated_300_residues
MNRLISFVIGLFILLAVASSMLFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVVFMDRRLQTIDVAANERFLTA
EKKSMVVDWFVKWRITDPRKFFVAFGGNLRGAQDRMTQRIDAVAREEFGKRTVADVVAGQREQVMQNIRVGMAEYAQSVG
VEIIDVRLKRVDLLPAISESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVVKGEGDAKASQI
YADAFGKDPSFAQFWRSMEAYRNTFRDKGNVMVLEPNSDFFRYMRSPGGNTAPAPSGGKK
>Mature_300_residues
MNRLISFVIGLFILLAVASSMLFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVVFMDRRLQTIDVAANERFLTA
EKKSMVVDWFVKWRITDPRKFFVAFGGNLRGAQDRMTQRIDAVAREEFGKRTVADVVAGQREQVMQNIRVGMAEYAQSVG
VEIIDVRLKRVDLLPAISESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVVKGEGDAKASQI
YADAFGKDPSFAQFWRSMEAYRNTFRDKGNVMVLEPNSDFFRYMRSPGGNTAPAPSGGKK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=316, Percent_Identity=36.7088607594937, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33954; Mature: 33954

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLISFVIGLFILLAVASSMLFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVV
CHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDRRLQTIDVAANERFLTAEKKSMVVDWFVKWRITDPRKFFVAFGGNLRGAQDRMTQRI
HHHHHHHEEEECCCCCEEEHHHHHHEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
DAVAREEFGKRTVADVVAGQREQVMQNIRVGMAEYAQSVGVEIIDVRLKRVDLLPAISES
HHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVVKGEGDAKASQI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHH
YADAFGKDPSFAQFWRSMEAYRNTFRDKGNVMVLEPNSDFFRYMRSPGGNTAPAPSGGKK
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRLISFVIGLFILLAVASSMLFVVDQRQYAVVFAFGEIKQVVREPGLHFKLPPPLQNVV
CHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDRRLQTIDVAANERFLTAEKKSMVVDWFVKWRITDPRKFFVAFGGNLRGAQDRMTQRI
HHHHHHHEEEECCCCCEEEHHHHHHEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
DAVAREEFGKRTVADVVAGQREQVMQNIRVGMAEYAQSVGVEIIDVRLKRVDLLPAISES
HHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLAEAYRDAQVVKGEGDAKASQI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHH
YADAFGKDPSFAQFWRSMEAYRNTFRDKGNVMVLEPNSDFFRYMRSPGGNTAPAPSGGKK
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]