Click here to switch to the map view.

The map label for this gene is talB

Identifier: 94311027

GI number: 94311027

Start: 2268201

End: 2269157

Strand: Direct

Name: talB

Synonym: Rmet_2089

Alternate gene names: 94311027

Gene position: 2268201-2269157 (Clockwise)

Preceding gene: 94311025

Following gene: 94311031

Centisome position: 57.74

GC content: 61.86

Gene sequence:

>957_bases
ATGAACGAGCTTGAACAACTGAGGCAGTTCACCACGGTAGTGGCCGACACCGGCGACTTCCAGTTGATGAAGCAATACAA
GCCACAGGACGCGACTACCAATCCGTCGCTGATTTTCAAGGCGGTACAGAAGCCGGAATACCGCCCGCTGCTGGAACAGG
CTGTGCGCGATCACCACGGCAATTCGGGGCTCGATGGCGTCATGGACCAGCTCCTGATCGCATTCGGCTGCGAGATCCTG
GCCATCGTGCCCGGCCGCGTGTCGACCGAGGTCGACGCCCGTCTGTCGTTCGATACCGAGGCCACCGTTGCCAAGGCGCG
CCACCTGATCGGCCTGTACGAGCAACGTGGCGTGGCACGCGAGCGCGTGCTGATCAAGATCGCCTCGACATGGGAAGGCA
TCCGCGCTGCCGAGGTCCTGCAACGCGAGAACATCCGCTGCAACATGACGCTGCTGTTCTCGCTGGCGCAGGCAGTGGCT
TGTGCCGAGGCCGGCGCGCAGCTGATCTCCCCGTTCGTGGGCCGCATTCTCGATTGGTACAAGAAGCAGGCTGGCGAGAA
ATGGGACCCCGTGGCGAACGGCGGCGAAAACGATCCCGGCGTGCGTTCCGTGCGCCAGATCTATGACTATTACAAGAAGT
TCGGCTACGCGACCGAGGTCATGGGTGCCAGTTTCCGCGGCACCGATCAGATCCTGTCGCTGGCAGGCTGCGACCTGCTG
ACGATCAGTCCGGAACTGCTCGAGCAGCTTGCAGGCGGACAGAGTGCCGTTGCGCTCAAGCTGTCCGTGGAACAGGCACA
GGCCGGCAACGTCGCGCGAATCGCCGCAGATGAACCCGCCTTCCGCTGGCAACTCAACGAAGATGCGATGGCAACGGAGA
AGCTCTCCGAAGGTATCCGCCTGTTTGCAGCCGATGCGGTGAAATTGGAAAAACTCGTCGGCGAACTGGCCAGTTGA

Upstream 100 bases:

>100_bases
GTTGGGAAACGCGTAGTGTAGCGGATTGGTTCCCCATCTCCGACGTTTACGCCACGCGCCACGCCGTTACAATGGCCCCT
CCCTCCGACGGAACCCAATC

Downstream 100 bases:

>100_bases
GTCGGGATCGCGGCTCTATCCAACACCTTGGAGGGAGCCGCGGATCCGCAGTCGAACAGTCGTTCAGACTGCCTGCGGCC
AGAGCAACGGCAGGCATTCA

Product: transaldolase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNELEQLRQFTTVVADTGDFQLMKQYKPQDATTNPSLIFKAVQKPEYRPLLEQAVRDHHGNSGLDGVMDQLLIAFGCEIL
AIVPGRVSTEVDARLSFDTEATVAKARHLIGLYEQRGVARERVLIKIASTWEGIRAAEVLQRENIRCNMTLLFSLAQAVA
CAEAGAQLISPFVGRILDWYKKQAGEKWDPVANGGENDPGVRSVRQIYDYYKKFGYATEVMGASFRGTDQILSLAGCDLL
TISPELLEQLAGGQSAVALKLSVEQAQAGNVARIAADEPAFRWQLNEDAMATEKLSEGIRLFAADAVKLEKLVGELAS

Sequences:

>Translated_318_residues
MNELEQLRQFTTVVADTGDFQLMKQYKPQDATTNPSLIFKAVQKPEYRPLLEQAVRDHHGNSGLDGVMDQLLIAFGCEIL
AIVPGRVSTEVDARLSFDTEATVAKARHLIGLYEQRGVARERVLIKIASTWEGIRAAEVLQRENIRCNMTLLFSLAQAVA
CAEAGAQLISPFVGRILDWYKKQAGEKWDPVANGGENDPGVRSVRQIYDYYKKFGYATEVMGASFRGTDQILSLAGCDLL
TISPELLEQLAGGQSAVALKLSVEQAQAGNVARIAADEPAFRWQLNEDAMATEKLSEGIRLFAADAVKLEKLVGELAS
>Mature_318_residues
MNELEQLRQFTTVVADTGDFQLMKQYKPQDATTNPSLIFKAVQKPEYRPLLEQAVRDHHGNSGLDGVMDQLLIAFGCEIL
AIVPGRVSTEVDARLSFDTEATVAKARHLIGLYEQRGVARERVLIKIASTWEGIRAAEVLQRENIRCNMTLLFSLAQAVA
CAEAGAQLISPFVGRILDWYKKQAGEKWDPVANGGENDPGVRSVRQIYDYYKKFGYATEVMGASFRGTDQILSLAGCDLL
TISPELLEQLAGGQSAVALKLSVEQAQAGNVARIAADEPAFRWQLNEDAMATEKLSEGIRLFAADAVKLEKLVGELAS

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=319, Percent_Identity=57.6802507836991, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI1788807, Length=319, Percent_Identity=57.9937304075235, Blast_Score=349, Evalue=1e-97,
Organism=Escherichia coli, GI1786189, Length=321, Percent_Identity=57.0093457943925, Blast_Score=348, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI25153750, Length=319, Percent_Identity=54.858934169279, Blast_Score=351, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI25153752, Length=165, Percent_Identity=57.5757575757576, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17570473, Length=93, Percent_Identity=56.989247311828, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321480, Length=321, Percent_Identity=54.8286604361371, Blast_Score=335, Evalue=6e-93,
Organism=Saccharomyces cerevisiae, GI6323386, Length=321, Percent_Identity=58.2554517133956, Blast_Score=328, Evalue=5e-91,
Organism=Drosophila melanogaster, GI45549185, Length=320, Percent_Identity=57.8125, Blast_Score=369, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_RALME (Q1LLK8)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_584237.1
- ProteinModelPortal:   Q1LLK8
- SMR:   Q1LLK8
- STRING:   Q1LLK8
- GeneID:   4038896
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_2089
- eggNOG:   COG0176
- HOGENOM:   HBG286747
- OMA:   GCEILAI
- PhylomeDB:   Q1LLK8
- ProtClustDB:   PRK05269
- BioCyc:   RMET266264:RMET_2089-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 34919; Mature: 34919

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELEQLRQFTTVVADTGDFQLMKQYKPQDATTNPSLIFKAVQKPEYRPLLEQAVRDHHG
CCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
NSGLDGVMDQLLIAFGCEILAIVPGRVSTEVDARLSFDTEATVAKARHLIGLYEQRGVAR
CCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHHCCHHH
ERVLIKIASTWEGIRAAEVLQRENIRCNMTLLFSLAQAVACAEAGAQLISPFVGRILDWY
HHHHEEEHHHHCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQAGEKWDPVANGGENDPGVRSVRQIYDYYKKFGYATEVMGASFRGTDQILSLAGCDLL
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHCCCEE
TISPELLEQLAGGQSAVALKLSVEQAQAGNVARIAADEPAFRWQLNEDAMATEKLSEGIR
EECHHHHHHHCCCCCEEEEEEEHHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHH
LFAADAVKLEKLVGELAS
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNELEQLRQFTTVVADTGDFQLMKQYKPQDATTNPSLIFKAVQKPEYRPLLEQAVRDHHG
CCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
NSGLDGVMDQLLIAFGCEILAIVPGRVSTEVDARLSFDTEATVAKARHLIGLYEQRGVAR
CCCHHHHHHHHHHHHCCCEEEECCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHHCCHHH
ERVLIKIASTWEGIRAAEVLQRENIRCNMTLLFSLAQAVACAEAGAQLISPFVGRILDWY
HHHHEEEHHHHCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQAGEKWDPVANGGENDPGVRSVRQIYDYYKKFGYATEVMGASFRGTDQILSLAGCDLL
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHCCCEE
TISPELLEQLAGGQSAVALKLSVEQAQAGNVARIAADEPAFRWQLNEDAMATEKLSEGIR
EECHHHHHHHCCCCCEEEEEEEHHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHH
LFAADAVKLEKLVGELAS
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA