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The map label for this gene is narL [H]

Identifier: 94311025

GI number: 94311025

Start: 2266681

End: 2267334

Strand: Direct

Name: narL [H]

Synonym: Rmet_2087

Alternate gene names: 94311025

Gene position: 2266681-2267334 (Clockwise)

Preceding gene: 94311024

Following gene: 94311027

Centisome position: 57.7

GC content: 62.84

Gene sequence:

>654_bases
ATGACCATCCGTATCCTACTGATCGACGATCACACATTGTTCCGCTCGGGTGTCCGTGCGCTGCTGCAGCGGCAGAGCGA
TTTCGAAGTGGTCGACGAAGCCGCCGATGGCGTGGAAGGCATCAAGCGGGCCAAACAGCATCGACCGGACGTGATCCTGC
TCGATCTGAATATGCCGGGCCTGTCAGGACTCGAAGCCCTGCAACTGCTGACGGAGGATCTGCCGGAATGCGCGGTGATT
GTGCTGACGGTATCCGAGGAAGGAGAAGAACTGGCCAGCGCCCTGCGCAGCGGTGCACGGGGTTACCTGATCAAGAACAT
AGAGACCGAAGCGCTGACGAGCGCGATCCGGCGGGCTGCCGCAGGGGAACCGGTGATCTCCGACACGATGACCGCCAAGC
TGGTGCAGCAGTTCAAGGCTCCGGCGGCCGCACCTGCCCTGCTAGAGCGTGGCGACGCGGCCCCTCTGACGGCGCGTGAG
CGGGACATTGTGCGCGGACTGGTACGCGGCGAAAGCAACAAGATGATCGCGCGCGCGCTGGGCGTGGCGGAGAGCACAGT
CAAGATTCACGTGCAGAACATTCTGAAGAAGCTCAATCTGGCCAGCCGCGTGCAAGTGGCCGTCTACGCAGTGGAGCATG
GGCTCACCGCGTGA

Upstream 100 bases:

>100_bases
ACGCCCGCCCAGGGGCTGGCGTCCGCGTCGCACTATCATTGCCGCGCGGCGAAACCATGCCGCATCCAGACGAGTTGCTG
GCGGCGCAGGAGTCTTCCCA

Downstream 100 bases:

>100_bases
GGCATTCGAAGCCGGGGGGCCATCACCGCCCGGCCTCTCACTCATACGACGCTTATGCGATTCAGTAATCCGAGCGCTGC
ACGCCCTGTTCGGTACCCAG

Product: luxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTIRILLIDDHTLFRSGVRALLQRQSDFEVVDEAADGVEGIKRAKQHRPDVILLDLNMPGLSGLEALQLLTEDLPECAVI
VLTVSEEGEELASALRSGARGYLIKNIETEALTSAIRRAAAGEPVISDTMTAKLVQQFKAPAAAPALLERGDAAPLTARE
RDIVRGLVRGESNKMIARALGVAESTVKIHVQNILKKLNLASRVQVAVYAVEHGLTA

Sequences:

>Translated_217_residues
MTIRILLIDDHTLFRSGVRALLQRQSDFEVVDEAADGVEGIKRAKQHRPDVILLDLNMPGLSGLEALQLLTEDLPECAVI
VLTVSEEGEELASALRSGARGYLIKNIETEALTSAIRRAAAGEPVISDTMTAKLVQQFKAPAAAPALLERGDAAPLTARE
RDIVRGLVRGESNKMIARALGVAESTVKIHVQNILKKLNLASRVQVAVYAVEHGLTA
>Mature_216_residues
TIRILLIDDHTLFRSGVRALLQRQSDFEVVDEAADGVEGIKRAKQHRPDVILLDLNMPGLSGLEALQLLTEDLPECAVIV
LTVSEEGEELASALRSGARGYLIKNIETEALTSAIRRAAAGEPVISDTMTAKLVQQFKAPAAAPALLERGDAAPLTARER
DIVRGLVRGESNKMIARALGVAESTVKIHVQNILKKLNLASRVQVAVYAVEHGLTA

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=205, Percent_Identity=47.8048780487805, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1788521, Length=211, Percent_Identity=39.8104265402844, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788222, Length=214, Percent_Identity=31.7757009345794, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790102, Length=205, Percent_Identity=32.6829268292683, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=26.6990291262136, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082052, Length=116, Percent_Identity=37.0689655172414, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=22.5961538461538, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788191, Length=105, Percent_Identity=34.2857142857143, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789937, Length=206, Percent_Identity=22.8155339805825, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23387; Mature: 23256

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRILLIDDHTLFRSGVRALLQRQSDFEVVDEAADGVEGIKRAKQHRPDVILLDLNMPG
CEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
LSGLEALQLLTEDLPECAVIVLTVSEEGEELASALRSGARGYLIKNIETEALTSAIRRAA
CCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
AGEPVISDTMTAKLVQQFKAPAAAPALLERGDAAPLTARERDIVRGLVRGESNKMIARAL
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
GVAESTVKIHVQNILKKLNLASRVQVAVYAVEHGLTA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIRILLIDDHTLFRSGVRALLQRQSDFEVVDEAADGVEGIKRAKQHRPDVILLDLNMPG
EEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
LSGLEALQLLTEDLPECAVIVLTVSEEGEELASALRSGARGYLIKNIETEALTSAIRRAA
CCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
AGEPVISDTMTAKLVQQFKAPAAAPALLERGDAAPLTARERDIVRGLVRGESNKMIARAL
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
GVAESTVKIHVQNILKKLNLASRVQVAVYAVEHGLTA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]