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The map label for this gene is ompB [H]

Identifier: 94310886

GI number: 94310886

Start: 2118232

End: 2119581

Strand: Direct

Name: ompB [H]

Synonym: Rmet_1948

Alternate gene names: 94310886

Gene position: 2118232-2119581 (Clockwise)

Preceding gene: 94310885

Following gene: 94310887

Centisome position: 53.93

GC content: 64.96

Gene sequence:

>1350_bases
GTGGCGACCGCTCTCGGCCGTACCGCAACGCGGTTCTTTGGTTCGCTCTTCTGGCGAACCTTCATGCTGATCGCCCTGTT
GCTGGCGATCTCGCTGGGTATCTGGTTCCAGAGCTACCGGCTCTTCGAACGCGCGCCGCGTGCCCAGCAGATCGCCATGC
AGGTAGTCAGCGTGGTCAAGCTCACCCGCGCGGCCCTGCTCTACTCGGACCCGGCTCGTCGCCGGTTCCTTCTGCTCGAC
CTCGTCCAGAACGAGGGCATCAAGGTCTATCCGCGCGAGAAGGACGATGACTTCGCCGCGCCCACGGCCAACCCGTTCCT
GACACAACTCGTGCAACAGGAGATTCGCGGCCGCCTGGGCGAAGACACGGTCATCGCGACCACGGTCAACGACATTCCCG
GCGTGTGGGTCAGCTTCGAAATCGAAGGCGACGACTACTGGGTCGCCATCAGCCCAGAACGATTCGAGCGCGTGCCAGGC
ATCCAGTGGCTCTGGTGGAGTATCGCGGCGCTGATGCTGTCGATCATCGGCGCGGCATTCATCACCGCGCGCGTCAACTA
TCCGCTCAAACGACTGGCCAACGCCGCGCGCCAGATCGGGTCCGGTGGCGATCCGCCGCCGCTGCGCGAACAGGGCGCAA
GCGAAGTGGCGCAGGCCAACCGCAGCTTCAACCAGATGGTGCACGACCTGCGTCAGCTCGATGACGACCGTGTAGTGATG
CTGGCAGGTATCTCGCACGATCTGCGCACGCCGCTCACCCGCCTGCGGCTGGAAACCGAAATGTCCCCCGTGGACAACGT
CACCCGCGACGCGATGATCGCCGACATCGAACAGATGGACGCGATCATCGGCCAGTTCCTGAACTATGCCCGGCCAGGGC
AGGAAGTCGTGGAACCGGTCGATCTGTCGACGCTCGTGCAAGAGTCCGTCGGCGTCTATGCCGCGCATGACGACGTGCGC
ATCCACGTGCGATCGAACGGCCCGGTGATGGCCATGGCCAACCGCATGGAAATCCAGCGCATTCTCGACAACCTCGTGGA
GAACGCGCGGCGCTACGCCAAGGACGAAGAGACCGGCATGGCCGAAGTGGAGATCTCCACGCGCGTCGAGGACAAGGATG
CGTTGCTGGTAGTGGCGGACAACGGCATGGGCGTGCCAGACGAAGAACTGTCGCTGCTGACGCGCCCGTTCTACCGGCTC
GACGCCGCCCGCAGCGAGGCCAAGGGGGCCGGCCTGGGCATGTCCATCGTCAACCGCATCCTGCAGCGCAACGGCGGCAG
GCTGGTCCTTGCCAACCGTCCGGCGCCCAAGTCCGGGCTGGTGGTCAGCGCAATCTTCCGGCGCGCCTGA

Upstream 100 bases:

>100_bases
ATCCGGGTAACCCGCGCTTCATCCAGACGGTCTGGGGCCTGGGTTATGTCTTTATCCCCGATGGCGTGAAGTAATTCCGG
TCGCACCTCACAGCTTCATC

Downstream 100 bases:

>100_bases
GCGCCATCTCGCGAAAATCGCCGCGAATGTATTCGATGCGGCGCATTGACAGGTTTTCGACAGCAAACGATAGGGTTTTG
TAAGCTCGCTGACAGGCGAT

Product: sensory histidine kinase in two-component regulatory system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MATALGRTATRFFGSLFWRTFMLIALLLAISLGIWFQSYRLFERAPRAQQIAMQVVSVVKLTRAALLYSDPARRRFLLLD
LVQNEGIKVYPREKDDDFAAPTANPFLTQLVQQEIRGRLGEDTVIATTVNDIPGVWVSFEIEGDDYWVAISPERFERVPG
IQWLWWSIAALMLSIIGAAFITARVNYPLKRLANAARQIGSGGDPPPLREQGASEVAQANRSFNQMVHDLRQLDDDRVVM
LAGISHDLRTPLTRLRLETEMSPVDNVTRDAMIADIEQMDAIIGQFLNYARPGQEVVEPVDLSTLVQESVGVYAAHDDVR
IHVRSNGPVMAMANRMEIQRILDNLVENARRYAKDEETGMAEVEISTRVEDKDALLVVADNGMGVPDEELSLLTRPFYRL
DAARSEAKGAGLGMSIVNRILQRNGGRLVLANRPAPKSGLVVSAIFRRA

Sequences:

>Translated_449_residues
MATALGRTATRFFGSLFWRTFMLIALLLAISLGIWFQSYRLFERAPRAQQIAMQVVSVVKLTRAALLYSDPARRRFLLLD
LVQNEGIKVYPREKDDDFAAPTANPFLTQLVQQEIRGRLGEDTVIATTVNDIPGVWVSFEIEGDDYWVAISPERFERVPG
IQWLWWSIAALMLSIIGAAFITARVNYPLKRLANAARQIGSGGDPPPLREQGASEVAQANRSFNQMVHDLRQLDDDRVVM
LAGISHDLRTPLTRLRLETEMSPVDNVTRDAMIADIEQMDAIIGQFLNYARPGQEVVEPVDLSTLVQESVGVYAAHDDVR
IHVRSNGPVMAMANRMEIQRILDNLVENARRYAKDEETGMAEVEISTRVEDKDALLVVADNGMGVPDEELSLLTRPFYRL
DAARSEAKGAGLGMSIVNRILQRNGGRLVLANRPAPKSGLVVSAIFRRA
>Mature_448_residues
ATALGRTATRFFGSLFWRTFMLIALLLAISLGIWFQSYRLFERAPRAQQIAMQVVSVVKLTRAALLYSDPARRRFLLLDL
VQNEGIKVYPREKDDDFAAPTANPFLTQLVQQEIRGRLGEDTVIATTVNDIPGVWVSFEIEGDDYWVAISPERFERVPGI
QWLWWSIAALMLSIIGAAFITARVNYPLKRLANAARQIGSGGDPPPLREQGASEVAQANRSFNQMVHDLRQLDDDRVVML
AGISHDLRTPLTRLRLETEMSPVDNVTRDAMIADIEQMDAIIGQFLNYARPGQEVVEPVDLSTLVQESVGVYAAHDDVRI
HVRSNGPVMAMANRMEIQRILDNLVENARRYAKDEETGMAEVEISTRVEDKDALLVVADNGMGVPDEELSLLTRPFYRLD
AARSEAKGAGLGMSIVNRILQRNGGRLVLANRPAPKSGLVVSAIFRRA

Specific function: Member of the two-component regulatory system envZ/ompR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates ompR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789808, Length=449, Percent_Identity=34.075723830735, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787894, Length=272, Percent_Identity=33.0882352941176, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=28.673835125448, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=268, Percent_Identity=26.865671641791, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790551, Length=268, Percent_Identity=27.6119402985075, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=213, Percent_Identity=27.2300469483568, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=24.3986254295533, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=284, Percent_Identity=27.8169014084507, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=217, Percent_Identity=27.1889400921659, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=212, Percent_Identity=25.9433962264151, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=24.1509433962264, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=23.7068965517241, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50126; Mature: 49995

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATALGRTATRFFGSLFWRTFMLIALLLAISLGIWFQSYRLFERAPRAQQIAMQVVSVVK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LTRAALLYSDPARRRFLLLDLVQNEGIKVYPREKDDDFAAPTANPFLTQLVQQEIRGRLG
HHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
EDTVIATTVNDIPGVWVSFEIEGDDYWVAISPERFERVPGIQWLWWSIAALMLSIIGAAF
CCCEEEEECCCCCCEEEEEEEECCEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ITARVNYPLKRLANAARQIGSGGDPPPLREQGASEVAQANRSFNQMVHDLRQLDDDRVVM
HHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LAGISHDLRTPLTRLRLETEMSPVDNVTRDAMIADIEQMDAIIGQFLNYARPGQEVVEPV
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
DLSTLVQESVGVYAAHDDVRIHVRSNGPVMAMANRMEIQRILDNLVENARRYAKDEETGM
HHHHHHHHHCCEEEECCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AEVEISTRVEDKDALLVVADNGMGVPDEELSLLTRPFYRLDAARSEAKGAGLGMSIVNRI
EEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LQRNGGRLVLANRPAPKSGLVVSAIFRRA
HHCCCCEEEEECCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
ATALGRTATRFFGSLFWRTFMLIALLLAISLGIWFQSYRLFERAPRAQQIAMQVVSVVK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LTRAALLYSDPARRRFLLLDLVQNEGIKVYPREKDDDFAAPTANPFLTQLVQQEIRGRLG
HHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
EDTVIATTVNDIPGVWVSFEIEGDDYWVAISPERFERVPGIQWLWWSIAALMLSIIGAAF
CCCEEEEECCCCCCEEEEEEEECCEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ITARVNYPLKRLANAARQIGSGGDPPPLREQGASEVAQANRSFNQMVHDLRQLDDDRVVM
HHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LAGISHDLRTPLTRLRLETEMSPVDNVTRDAMIADIEQMDAIIGQFLNYARPGQEVVEPV
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
DLSTLVQESVGVYAAHDDVRIHVRSNGPVMAMANRMEIQRILDNLVENARRYAKDEETGM
HHHHHHHHHCCEEEECCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AEVEISTRVEDKDALLVVADNGMGVPDEELSLLTRPFYRLDAARSEAKGAGLGMSIVNRI
EEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LQRNGGRLVLANRPAPKSGLVVSAIFRRA
HHCCCCEEEEECCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6292200; 2997120; 9278503; 8132603; 2277041; 2824492; 1323560; 9817206; 10426948 [H]