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The map label for this gene is ompR [H]

Identifier: 94310885

GI number: 94310885

Start: 2117483

End: 2118205

Strand: Direct

Name: ompR [H]

Synonym: Rmet_1947

Alternate gene names: 94310885

Gene position: 2117483-2118205 (Clockwise)

Preceding gene: 94310883

Following gene: 94310886

Centisome position: 53.91

GC content: 63.07

Gene sequence:

>723_bases
ATGGAAAATACCAGCCACAAGATTCTCGTCGTGGACGACGACCCGCGCCTGCGCGATCTTCTACGCCGCTATCTCGGCGA
GCAGGGCTTCACGGTCCTCGTGGCGGAAAACGCCACGGCCATGAATAAGCTCTGGCTGCGCGAGCGTTTCGACCTGCTGG
TGCTGGACCTGATGATGCCGGGCGAGGACGGCCTTTCCATCTGCCGCCGCCTGCGAGGCGCCAACGACCAGACCCCGATC
ATCATGCTCACCGCCAAGGGTGAGGACGTGGACCGTATCGTCGGCCTGGAAATGGGCGCGGACGACTATCTGCCCAAGCC
CTTCAACCCGCGTGAACTGATCGCGCGGATTCACGCCGTGCTGCGCCGCAAGGGTCCCGCCGAAGTGCCTGGCGCCCCGT
CGGAAACCCCGGAAACGTTCGCCTTCGGCGATTTCGTACTCAACCTGGCCACGCGTACGCTGACCAAGAACGACGAGGAA
ATCACGCTCACCACGGGCGAGTTCTCGGTGCTCAAGGTTTTCGCGCGCCACCCACGCCAGCCGCTCTCGCGCGAAAAGCT
CATGGAAATGGCACGCGGCCGCGAGTACGAAGTCTTCGACCGCAGCCTGGACGTGCAGATTTCTCGCCTGCGCAAGCTGA
TCGAGCCGGATCCGGGTAACCCGCGCTTCATCCAGACGGTCTGGGGCCTGGGTTATGTCTTTATCCCCGATGGCGTGAAG
TAA

Upstream 100 bases:

>100_bases
GTAAATGCACAAAAGGTGCACGCCGCCATACCACAGGGTAAAGTATGTAACGTTTTGTTAAGCCATTTTGAGCGAAAGCG
ATAGTCGCTAAGATACCGCC

Downstream 100 bases:

>100_bases
TTCCGGTCGCACCTCACAGCTTCATCGTGGCGACCGCTCTCGGCCGTACCGCAACGCGGTTCTTTGGTTCGCTCTTCTGG
CGAACCTTCATGCTGATCGC

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MENTSHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRKGPAEVPGAPSETPETFAFGDFVLNLATRTLTKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDPGNPRFIQTVWGLGYVFIPDGVK

Sequences:

>Translated_240_residues
MENTSHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRKGPAEVPGAPSETPETFAFGDFVLNLATRTLTKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDPGNPRFIQTVWGLGYVFIPDGVK
>Mature_240_residues
MENTSHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRKGPAEVPGAPSETPETFAFGDFVLNLATRTLTKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDPGNPRFIQTVWGLGYVFIPDGVK

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=66.5254237288136, Blast_Score=325, Evalue=1e-90,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=38.1974248927039, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=42.8571428571429, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=38.5593220338983, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=36.6666666666667, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=34.1991341991342, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.6223175965665, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=37.4468085106383, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=31.7391304347826, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=33.1877729257642, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=34.7639484978541, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=30.7017543859649, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.9004329004329, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=33.6363636363636, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788550, Length=163, Percent_Identity=26.9938650306748, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788905, Length=126, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788191, Length=129, Percent_Identity=32.5581395348837, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=130, Percent_Identity=30, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27317; Mature: 27317

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTSHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCC
GEDGLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAV
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
LRRKGPAEVPGAPSETPETFAFGDFVLNLATRTLTKNDEEITLTTGEFSVLKVFARHPRQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCC
PLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDPGNPRFIQTVWGLGYVFIPDGVK
CCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MENTSHKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCC
GEDGLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAV
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
LRRKGPAEVPGAPSETPETFAFGDFVLNLATRTLTKNDEEITLTTGEFSVLKVFARHPRQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCC
PLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDPGNPRFIQTVWGLGYVFIPDGVK
CCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]