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The map label for this gene is dppA [H]

Identifier: 94310870

GI number: 94310870

Start: 2100202

End: 2101962

Strand: Direct

Name: dppA [H]

Synonym: Rmet_1932

Alternate gene names: 94310870

Gene position: 2100202-2101962 (Clockwise)

Preceding gene: 94310868

Following gene: 94310871

Centisome position: 53.47

GC content: 62.58

Gene sequence:

>1761_bases
ATGGTGCATGGCCACTGGCACATCAATTGCTTGACGGAGCGATGTCCATCCACAGCCCATTCCGTTTCAGGAGCCCCGCC
CGTGACCTACTCCACGCCCTCCCATTCGAAAGGCCTTTCCGCCGCGATTCGCACTGTCTCCGCCGCCGTCACGTTGTCGC
TGCTGGCCCTGCCCGGCGCCGCGATGGCCGAGAAGGTGCTCCGCATCGGCATGACGGCCGCTGACATCCCGCGCACACTC
GGCCAGCCCGACCAGGGTTTCGAAGGCAACCGGTTCACCGGCATCCCGATGTATGACGCACTCACCCAGTGGGACCTGTC
GAAGAGCAACGGCCCAAGCCTGCTGATTCCCGACCTGGCAACCGAATGGAAGGTCGACGACAAGAACAAGACCGAATGGA
CGTTCAAGCTGCGCCCAGGCGTGAAGTTTCACGACGGCTCGCCGTTCAATGCCGATGCCGTGGTCTGGAACGTCAACAAG
GTGCTCGACAAGACCGCGAAGCAGTTCGACCCCAGCCAGGTTGGCGTCACCGCTTCGCGCATGCCCACGTTGCGTAGCGC
GAAGAAGATCGATGACATGACCGTGCAACTCGTCACGTCAGAGCCGGATTCGTTCCTGCCGTACAACGTGTCGAACCTGT
TCATGGCGTCGCCGACCCAGTGGGAGAAGAAGTACGCGGCGGTCCCTGCCTCCGTGACCGAGCCGGCGGAGCGCAGCAAG
CAGGCATGGGTGGCCTTTGCGGCAGATGCATCGGGTACGGGCCCATTCAAGATGACCCGATTCGTCCCGCGCGAACGCCT
GGAGCTTGCCAAGAACCCCGCCTACTGGGACAGCAAGCGGGTGCCAAAGATCGACAAGGTCGTGATGCTGCCGATGCCCG
AGGCCAATGCACGCACCGCGGCACTGCTGTCAGGCCAGGTGGACTGGATCGAGGCCCCGGCACCTGATGCCATCGCGCAG
ATCAAGAGCCGTGGCTTCGATGTGTACGCCAACGCGCAGCCGCACATGTGGCCATGGCAATTGTCATTCGCGCCGAATTC
CCCGTGGCTCGACAAGCGCGTGCGCCAGGCCGCGAACCTTTGCGTGAATCGCGCCGGCCTGAAGACACTGCTCGGCGGCT
ACATGGCCGAGGCCAAGGGCATCGTCGAAGCCGGAAACCCGTGGTGGGGCAATCCGGCATTCACCATCAAGTACGACCCC
GCGGCCGCGCGCAAGCTGATGACGGAGGCCGGATACTCCGCCGCCAAGCCGGTGAAGGTAAAGGTCCAGGTATCCGCATC
GGGCTCCGGCCAGATGCAGCCGCTGCCCATGAACGAGTACGTACAGCAAAACCTCAAGGAGTGCTTCTTCGACGTGGACT
TTGACGTCGTCGAATGGAACACGCTGTTCACGAACTGGCGCATTGGCGCGAAGGACGCGAGCGCGCATGGCGCCAACGCG
ATCAACGTGAGCTTTGCGGCGATGGACCCTTTCTTTGCCATGGTCCGCTTCGTCAGCACGAAGACGCAGCCGCCGGTTTC
GAACAACTGGGGCTACTTCGGCAACGCGGAGTTTGACAAGCTGATCGAGACCGCGCGCACCTCGTTTGGCGAAAAGGAAC
GAGATGCCGCGCTGGCAAAACTCCACGCGCGCATCGTTGAAGAAGCGCCATTCGTGCTGATCGCCCACGATGTGGGCCCG
CGAGCGATCTCCCGGAAGATCAAGGGGGTGGTGCAGCCGCAGAGCTGGTTCATCGATATCGCGACGATGTCTATCGATTG
A

Upstream 100 bases:

>100_bases
CCATGTCTGTGTTGTCTGCAGTGAGTGAACATCAACCTGGGTACGAGCAAGAAGCAGACCACTGACAGGTGCGGACAGTC
TCGGCCATGACCACCCGTCG

Downstream 100 bases:

>100_bases
CGGACTCGCCGCAGTGCCCTCCTCCGCGGAAGGGGGCACTTTCCCGCGCCAACGTATTTGCCTATTCCGCAAGCCGGCCA
TAGACCATGACTTACCTGCT

Product: PepT family ABC transporter periplasmic protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MVHGHWHINCLTERCPSTAHSVSGAPPVTYSTPSHSKGLSAAIRTVSAAVTLSLLALPGAAMAEKVLRIGMTAADIPRTL
GQPDQGFEGNRFTGIPMYDALTQWDLSKSNGPSLLIPDLATEWKVDDKNKTEWTFKLRPGVKFHDGSPFNADAVVWNVNK
VLDKTAKQFDPSQVGVTASRMPTLRSAKKIDDMTVQLVTSEPDSFLPYNVSNLFMASPTQWEKKYAAVPASVTEPAERSK
QAWVAFAADASGTGPFKMTRFVPRERLELAKNPAYWDSKRVPKIDKVVMLPMPEANARTAALLSGQVDWIEAPAPDAIAQ
IKSRGFDVYANAQPHMWPWQLSFAPNSPWLDKRVRQAANLCVNRAGLKTLLGGYMAEAKGIVEAGNPWWGNPAFTIKYDP
AAARKLMTEAGYSAAKPVKVKVQVSASGSGQMQPLPMNEYVQQNLKECFFDVDFDVVEWNTLFTNWRIGAKDASAHGANA
INVSFAAMDPFFAMVRFVSTKTQPPVSNNWGYFGNAEFDKLIETARTSFGEKERDAALAKLHARIVEEAPFVLIAHDVGP
RAISRKIKGVVQPQSWFIDIATMSID

Sequences:

>Translated_586_residues
MVHGHWHINCLTERCPSTAHSVSGAPPVTYSTPSHSKGLSAAIRTVSAAVTLSLLALPGAAMAEKVLRIGMTAADIPRTL
GQPDQGFEGNRFTGIPMYDALTQWDLSKSNGPSLLIPDLATEWKVDDKNKTEWTFKLRPGVKFHDGSPFNADAVVWNVNK
VLDKTAKQFDPSQVGVTASRMPTLRSAKKIDDMTVQLVTSEPDSFLPYNVSNLFMASPTQWEKKYAAVPASVTEPAERSK
QAWVAFAADASGTGPFKMTRFVPRERLELAKNPAYWDSKRVPKIDKVVMLPMPEANARTAALLSGQVDWIEAPAPDAIAQ
IKSRGFDVYANAQPHMWPWQLSFAPNSPWLDKRVRQAANLCVNRAGLKTLLGGYMAEAKGIVEAGNPWWGNPAFTIKYDP
AAARKLMTEAGYSAAKPVKVKVQVSASGSGQMQPLPMNEYVQQNLKECFFDVDFDVVEWNTLFTNWRIGAKDASAHGANA
INVSFAAMDPFFAMVRFVSTKTQPPVSNNWGYFGNAEFDKLIETARTSFGEKERDAALAKLHARIVEEAPFVLIAHDVGP
RAISRKIKGVVQPQSWFIDIATMSID
>Mature_586_residues
MVHGHWHINCLTERCPSTAHSVSGAPPVTYSTPSHSKGLSAAIRTVSAAVTLSLLALPGAAMAEKVLRIGMTAADIPRTL
GQPDQGFEGNRFTGIPMYDALTQWDLSKSNGPSLLIPDLATEWKVDDKNKTEWTFKLRPGVKFHDGSPFNADAVVWNVNK
VLDKTAKQFDPSQVGVTASRMPTLRSAKKIDDMTVQLVTSEPDSFLPYNVSNLFMASPTQWEKKYAAVPASVTEPAERSK
QAWVAFAADASGTGPFKMTRFVPRERLELAKNPAYWDSKRVPKIDKVVMLPMPEANARTAALLSGQVDWIEAPAPDAIAQ
IKSRGFDVYANAQPHMWPWQLSFAPNSPWLDKRVRQAANLCVNRAGLKTLLGGYMAEAKGIVEAGNPWWGNPAFTIKYDP
AAARKLMTEAGYSAAKPVKVKVQVSASGSGQMQPLPMNEYVQQNLKECFFDVDFDVVEWNTLFTNWRIGAKDASAHGANA
INVSFAAMDPFFAMVRFVSTKTQPPVSNNWGYFGNAEFDKLIETARTSFGEKERDAALAKLHARIVEEAPFVLIAHDVGP
RAISRKIKGVVQPQSWFIDIATMSID

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=518, Percent_Identity=25.8687258687259, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081878, Length=494, Percent_Identity=24.0890688259109, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787762, Length=533, Percent_Identity=24.765478424015, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787052, Length=345, Percent_Identity=28.1159420289855, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787495, Length=550, Percent_Identity=22.1818181818182, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787551, Length=478, Percent_Identity=23.0125523012552, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64385; Mature: 64385

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHGHWHINCLTERCPSTAHSVSGAPPVTYSTPSHSKGLSAAIRTVSAAVTLSLLALPGA
CCCCEEEEEEHHHHCCCHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
AMAEKVLRIGMTAADIPRTLGQPDQGFEGNRFTGIPMYDALTQWDLSKSNGPSLLIPDLA
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHCCCCCCCCCEEEECCCC
TEWKVDDKNKTEWTFKLRPGVKFHDGSPFNADAVVWNVNKVLDKTAKQFDPSQVGVTASR
CCCCCCCCCCCEEEEEECCCEEECCCCCCCCCEEEEEHHHHHHHHHHHCCCHHCCEEHHH
MPTLRSAKKIDDMTVQLVTSEPDSFLPYNVSNLFMASPTQWEKKYAAVPASVTEPAERSK
CCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCHHHHCC
QAWVAFAADASGTGPFKMTRFVPRERLELAKNPAYWDSKRVPKIDKVVMLPMPEANARTA
CEEEEEEECCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEE
ALLSGQVDWIEAPAPDAIAQIKSRGFDVYANAQPHMWPWQLSFAPNSPWLDKRVRQAANL
EEECCCCCEECCCCCHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHH
CVNRAGLKTLLGGYMAEAKGIVEAGNPWWGNPAFTIKYDPAAARKLMTEAGYSAAKPVKV
HHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCEEE
KVQVSASGSGQMQPLPMNEYVQQNLKECFFDVDFDVVEWNTLFTNWRIGAKDASAHGANA
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCCCCCCE
INVSFAAMDPFFAMVRFVSTKTQPPVSNNWGYFGNAEFDKLIETARTSFGEKERDAALAK
EEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
LHARIVEEAPFVLIAHDVGPRAISRKIKGVVQPQSWFIDIATMSID
HHHHHHHCCCEEEEEECCCHHHHHHHHHCEECCCEEEEEEEEEECC
>Mature Secondary Structure
MVHGHWHINCLTERCPSTAHSVSGAPPVTYSTPSHSKGLSAAIRTVSAAVTLSLLALPGA
CCCCEEEEEEHHHHCCCHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
AMAEKVLRIGMTAADIPRTLGQPDQGFEGNRFTGIPMYDALTQWDLSKSNGPSLLIPDLA
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHCCCCCCCCCEEEECCCC
TEWKVDDKNKTEWTFKLRPGVKFHDGSPFNADAVVWNVNKVLDKTAKQFDPSQVGVTASR
CCCCCCCCCCCEEEEEECCCEEECCCCCCCCCEEEEEHHHHHHHHHHHCCCHHCCEEHHH
MPTLRSAKKIDDMTVQLVTSEPDSFLPYNVSNLFMASPTQWEKKYAAVPASVTEPAERSK
CCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCCHHHHCC
QAWVAFAADASGTGPFKMTRFVPRERLELAKNPAYWDSKRVPKIDKVVMLPMPEANARTA
CEEEEEEECCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEE
ALLSGQVDWIEAPAPDAIAQIKSRGFDVYANAQPHMWPWQLSFAPNSPWLDKRVRQAANL
EEECCCCCEECCCCCHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHH
CVNRAGLKTLLGGYMAEAKGIVEAGNPWWGNPAFTIKYDPAAARKLMTEAGYSAAKPVKV
HHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCEEE
KVQVSASGSGQMQPLPMNEYVQQNLKECFFDVDFDVVEWNTLFTNWRIGAKDASAHGANA
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCCCCCCE
INVSFAAMDPFFAMVRFVSTKTQPPVSNNWGYFGNAEFDKLIETARTSFGEKERDAALAK
EEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
LHARIVEEAPFVLIAHDVGPRAISRKIKGVVQPQSWFIDIATMSID
HHHHHHHCCCEEEEEECCCHHHHHHHHHCEECCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]