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The map label for this gene is creB [H]

Identifier: 94310594

GI number: 94310594

Start: 1787449

End: 1788147

Strand: Reverse

Name: creB [H]

Synonym: Rmet_1652

Alternate gene names: 94310594

Gene position: 1788147-1787449 (Counterclockwise)

Preceding gene: 94310595

Following gene: 94310593

Centisome position: 45.52

GC content: 61.95

Gene sequence:

>699_bases
ATGAAACAGCCAGCCGTACTTGTAGTGGAAGATGAATCAGCCATTGCGGACACGATTCTGTACGCCCTACGCACGGAAGG
TATGCAGGTCGAGACTTGCACGCTGGGGAGTGAGGCATTGGATCGCGTGCGATCACGACGCCCCGATCTCGTTATCCTCG
ACGTTGGGCTGCCAGATATCAGCGGTTTTGAGGTTTGCCGCTCGATGCGGACGTTTTCGGACGTTCCCGTCATCTTCCTG
ACTGCCCGGCACGAGGAAATCGACCGCATCGTCGGGCTCGAAATTGGCGCGGATGACTACGTGGTAAAGCCATTCTCGCC
ACGTGAGCTTGCCGCTCGCGTGCGCGTGATCCTCCGTCGCGCCAAGGGCGCCAGCGACTCACCCCACCCATCGCCAATGG
CCCAGGAGGAAGCCGATTTCGTCCATGACACCGACGGCGCCCGCCTGGCCTATCGTGGCCGATGGCTGGACCTCACCCGC
TACGAATACCGCCTGCTGGCGCTTCTGGTGCAACACCCGGGGCGCATCTTCGCCCGCTCGCAGCTCATGGATCTGGTCTG
GCACGATTCGCTCGATACGGTCGATCGTACCGTCGACACGCACGTCAAGACGCTCCGAGCCAAGCTCCGCGAGATCGCCC
CCGCTGGCGACCCGATCCGGACCCATCGCGGCATGGGCTACTCACTCGAATCACGATAA

Upstream 100 bases:

>100_bases
CTGTTGCATTCGGCGCCTTTGCGATGGGTCGCGGAACGCATCTATTTCCACAAACGCGGCGTCGCGGCAGAGATTTAAAC
CTGATAGCGAGACTTGTGTA

Downstream 100 bases:

>100_bases
GGAAGATAAGGGCATTCCATGCATATCGGCCTGCGCATCTTCTTCGGCTTCTTCCTGATCGTCGGGCTGGCAGCGTTCCT
GACCTTGCGCGTGTTTGTCC

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKQPAVLVVEDESAIADTILYALRTEGMQVETCTLGSEALDRVRSRRPDLVILDVGLPDISGFEVCRSMRTFSDVPVIFL
TARHEEIDRIVGLEIGADDYVVKPFSPRELAARVRVILRRAKGASDSPHPSPMAQEEADFVHDTDGARLAYRGRWLDLTR
YEYRLLALLVQHPGRIFARSQLMDLVWHDSLDTVDRTVDTHVKTLRAKLREIAPAGDPIRTHRGMGYSLESR

Sequences:

>Translated_232_residues
MKQPAVLVVEDESAIADTILYALRTEGMQVETCTLGSEALDRVRSRRPDLVILDVGLPDISGFEVCRSMRTFSDVPVIFL
TARHEEIDRIVGLEIGADDYVVKPFSPRELAARVRVILRRAKGASDSPHPSPMAQEEADFVHDTDGARLAYRGRWLDLTR
YEYRLLALLVQHPGRIFARSQLMDLVWHDSLDTVDRTVDTHVKTLRAKLREIAPAGDPIRTHRGMGYSLESR
>Mature_232_residues
MKQPAVLVVEDESAIADTILYALRTEGMQVETCTLGSEALDRVRSRRPDLVILDVGLPDISGFEVCRSMRTFSDVPVIFL
TARHEEIDRIVGLEIGADDYVVKPFSPRELAARVRVILRRAKGASDSPHPSPMAQEEADFVHDTDGARLAYRGRWLDLTR
YEYRLLALLVQHPGRIFARSQLMDLVWHDSLDTVDRTVDTHVKTLRAKLREIAPAGDPIRTHRGMGYSLESR

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=56.0869565217391, Blast_Score=246, Evalue=7e-67,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=40.8695652173913, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=37.2881355932203, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=40.3508771929825, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=36.2445414847162, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=33.4782608695652, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=34.9557522123894, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.6812227074236, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.920704845815, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.4821428571429, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=32.1739130434783, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.8777292576419, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=30.2631578947368, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=31.6239316239316, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26189; Mature: 26189

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQPAVLVVEDESAIADTILYALRTEGMQVETCTLGSEALDRVRSRRPDLVILDVGLPDI
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCC
SGFEVCRSMRTFSDVPVIFLTARHEEIDRIVGLEIGADDYVVKPFSPRELAARVRVILRR
CHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCEEECCCCEEECCCCHHHHHHHHHHHHHH
AKGASDSPHPSPMAQEEADFVHDTDGARLAYRGRWLDLTRYEYRLLALLVQHPGRIFARS
HCCCCCCCCCCCCCHHHCCCEECCCCCEEEECCCEEEHHHHHHHHHHHHHHCCCHHHHHH
QLMDLVWHDSLDTVDRTVDTHVKTLRAKLREIAPAGDPIRTHRGMGYSLESR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEECCCC
>Mature Secondary Structure
MKQPAVLVVEDESAIADTILYALRTEGMQVETCTLGSEALDRVRSRRPDLVILDVGLPDI
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCC
SGFEVCRSMRTFSDVPVIFLTARHEEIDRIVGLEIGADDYVVKPFSPRELAARVRVILRR
CHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCEEECCCCEEECCCCHHHHHHHHHHHHHH
AKGASDSPHPSPMAQEEADFVHDTDGARLAYRGRWLDLTRYEYRLLALLVQHPGRIFARS
HCCCCCCCCCCCCCHHHCCCEECCCCCEEEECCCEEEHHHHHHHHHHHHHHCCCHHHHHH
QLMDLVWHDSLDTVDRTVDTHVKTLRAKLREIAPAGDPIRTHRGMGYSLESR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]