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The map label for this gene is qseC [H]

Identifier: 94310568

GI number: 94310568

Start: 1754314

End: 1755750

Strand: Reverse

Name: qseC [H]

Synonym: Rmet_1626

Alternate gene names: 94310568

Gene position: 1755750-1754314 (Counterclockwise)

Preceding gene: 94310569

Following gene: 94310566

Centisome position: 44.7

GC content: 67.08

Gene sequence:

>1437_bases
ATGAAAACAGGCAGCCTGAGGCTGCAGATCACGCTCTGGCTGCTGATACCGCTGCTGGGGCTGCTGGCATTCGACGCGTG
GCTGACCGATCGGCGCGCGATGTCCGCGGCCCACCAGGCATTCGACCGCACGCTGGCCGCATCGCTCAAGTCCATGCGCG
AAGGGATTTCGCTGCGCGACGGACGCGTCGAAGTGGAAATCCCCAATCTGGCCCTGGAAGTCTTCGACGCCGAGGATGGC
TCGCGCGTCTACTACCAGATTCGCGACGAGCGTGGCACGACGATCACCGGCTATGAAGGGCTGCCGATGCCGGAAGGACC
GGTGAATTCGCTCTATCGCACCCAGTTCTACGACGCCGAGTACCTTGGCGTGCCCGTCCGCATGGCAGCCATGCCACTGC
CGCTGCACGACGTCCGCTCGGCCCGCACGCAAATGGTCTGGGTGCTGCTGGCCGAATCGACCGAGCCGCGCGAGCAGCTT
GCCAGCGACATCCTGGTCGGCTCGCTGCTGCAGGAACTGATGCTGATCAGCCTGGCGCTGGGCATCGTCTGGCTTGGCGT
GCGGCGGGGCCTGCTGCCGCTGCAACGGCTGTCCGACGCCATGTCCGCACGCGGCCCCGACGATCTGGAGCCATTGGAAG
ACACCGCGCTGCCGGTCGAAATGAAGCCACTGGTGGCCGCAGTGAACCAGTATGTGGCCCGGCTGCACCGCATGATAGAA
GGCCGCAAGCGTTTCTTTGCCGATGCCGCGCACCAACTCAAGACGCCGTTGGCCATCATCCAGGCCGAATCGGAACTCGC
ACTGCGCGAGAAGGACCTGCCGAGCGTGCGCGCGCACGTCGAGCGGCTGCATGGATCCGTGCAGCAGGCCGCCAAGGAAG
TCGCCCAGCTGCTGTCGCTGTCGCGGCTCGAGCCAGACAGCGGCTACGCGCCCACGCTGCGGCACCTGCGATTGGATACG
CTGGCGCAGAACGTGGCGCTTGAATGGGCGCCGCTGGCCCGGCGCGCGGGGGTGGATCTGGGTTTCGAGGGTCGCGGCCC
GGCCGACATCGACGGCCAGACCGAACTGCTGCAGGAACTGCTCGGGAATCTGATCGACAACGCTATCCGCTATGCGGGCG
CCGGCGCGATGGTCACGGTGCGCGTCGACGGGCAACGGCTGGCCGTAGAGGACAACGGTCCCGGCGTGCCCGCGTTCGAG
CGCGAGTCGATCTTCAAGCGCTTCTATCGTGGAGAGTCGAGCGCTAGCCGCGATGGCAGCGGCCTGGGGCTGTCGATCGT
GCGGGAGATCGCCCGCATTCATGGCGCCGCCGTCGCGCTGGAAAGCACGCCGGGCGGCGGCCTGACCGTGGTGGTTACTT
TCCCTGCGCCTGCGCTTGCGTCTGGGCCAGGGCCGGCTTCGACAGATTCCCCCGGGCGCGCTGCAGAAAGCCGATGA

Upstream 100 bases:

>100_bases
TGCGCAAGAAGCTGGAAGGCAGCGGCGTGAGCATCGTCACGCTGCGCGGGCTCGGCTATCTGCTGGAATCACGCGACACC
GCCACGTCGGACGCGCGCCA

Downstream 100 bases:

>100_bases
ATTGCTCCGCTTCTTCGGCGTTGAAGCCGTTGAGCGCCTCCGATGTCACCACATCCCCCACCTCGCGCGCGGCATGCAGT
GCCTGCTCCGCTTTTTCCGT

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MKTGSLRLQITLWLLIPLLGLLAFDAWLTDRRAMSAAHQAFDRTLAASLKSMREGISLRDGRVEVEIPNLALEVFDAEDG
SRVYYQIRDERGTTITGYEGLPMPEGPVNSLYRTQFYDAEYLGVPVRMAAMPLPLHDVRSARTQMVWVLLAESTEPREQL
ASDILVGSLLQELMLISLALGIVWLGVRRGLLPLQRLSDAMSARGPDDLEPLEDTALPVEMKPLVAAVNQYVARLHRMIE
GRKRFFADAAHQLKTPLAIIQAESELALREKDLPSVRAHVERLHGSVQQAAKEVAQLLSLSRLEPDSGYAPTLRHLRLDT
LAQNVALEWAPLARRAGVDLGFEGRGPADIDGQTELLQELLGNLIDNAIRYAGAGAMVTVRVDGQRLAVEDNGPGVPAFE
RESIFKRFYRGESSASRDGSGLGLSIVREIARIHGAAVALESTPGGGLTVVVTFPAPALASGPGPASTDSPGRAAESR

Sequences:

>Translated_478_residues
MKTGSLRLQITLWLLIPLLGLLAFDAWLTDRRAMSAAHQAFDRTLAASLKSMREGISLRDGRVEVEIPNLALEVFDAEDG
SRVYYQIRDERGTTITGYEGLPMPEGPVNSLYRTQFYDAEYLGVPVRMAAMPLPLHDVRSARTQMVWVLLAESTEPREQL
ASDILVGSLLQELMLISLALGIVWLGVRRGLLPLQRLSDAMSARGPDDLEPLEDTALPVEMKPLVAAVNQYVARLHRMIE
GRKRFFADAAHQLKTPLAIIQAESELALREKDLPSVRAHVERLHGSVQQAAKEVAQLLSLSRLEPDSGYAPTLRHLRLDT
LAQNVALEWAPLARRAGVDLGFEGRGPADIDGQTELLQELLGNLIDNAIRYAGAGAMVTVRVDGQRLAVEDNGPGVPAFE
RESIFKRFYRGESSASRDGSGLGLSIVREIARIHGAAVALESTPGGGLTVVVTFPAPALASGPGPASTDSPGRAAESR
>Mature_478_residues
MKTGSLRLQITLWLLIPLLGLLAFDAWLTDRRAMSAAHQAFDRTLAASLKSMREGISLRDGRVEVEIPNLALEVFDAEDG
SRVYYQIRDERGTTITGYEGLPMPEGPVNSLYRTQFYDAEYLGVPVRMAAMPLPLHDVRSARTQMVWVLLAESTEPREQL
ASDILVGSLLQELMLISLALGIVWLGVRRGLLPLQRLSDAMSARGPDDLEPLEDTALPVEMKPLVAAVNQYVARLHRMIE
GRKRFFADAAHQLKTPLAIIQAESELALREKDLPSVRAHVERLHGSVQQAAKEVAQLLSLSRLEPDSGYAPTLRHLRLDT
LAQNVALEWAPLARRAGVDLGFEGRGPADIDGQTELLQELLGNLIDNAIRYAGAGAMVTVRVDGQRLAVEDNGPGVPAFE
RESIFKRFYRGESSASRDGSGLGLSIVREIARIHGAAVALESTPGGGLTVVVTFPAPALASGPGPASTDSPGRAAESR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=351, Percent_Identity=33.9031339031339, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=32.0819112627986, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=268, Percent_Identity=31.3432835820896, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786783, Length=344, Percent_Identity=29.0697674418605, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788279, Length=336, Percent_Identity=27.3809523809524, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=31.9672131147541, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=282, Percent_Identity=30.1418439716312, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=30.6306306306306, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=28.8888888888889, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787374, Length=310, Percent_Identity=28.3870967741935, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789808, Length=290, Percent_Identity=24.8275862068966, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790861, Length=315, Percent_Identity=29.5238095238095, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=246, Percent_Identity=27.2357723577236, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=25.5411255411255, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=25.3393665158371, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=251, Percent_Identity=26.2948207171315, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=297, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=24.8868778280543, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51991; Mature: 51991

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGSLRLQITLWLLIPLLGLLAFDAWLTDRRAMSAAHQAFDRTLAASLKSMREGISLRD
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GRVEVEIPNLALEVFDAEDGSRVYYQIRDERGTTITGYEGLPMPEGPVNSLYRTQFYDAE
CEEEEEECCEEEEEEECCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHCCCCH
YLGVPVRMAAMPLPLHDVRSARTQMVWVLLAESTEPREQLASDILVGSLLQELMLISLAL
HCCCCHHHHHCCCCHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIVWLGVRRGLLPLQRLSDAMSARGPDDLEPLEDTALPVEMKPLVAAVNQYVARLHRMIE
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GRKRFFADAAHQLKTPLAIIQAESELALREKDLPSVRAHVERLHGSVQQAAKEVAQLLSL
HHHHHHHHHHHHHHCCHHEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLEPDSGYAPTLRHLRLDTLAQNVALEWAPLARRAGVDLGFEGRGPADIDGQTELLQEL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
LGNLIDNAIRYAGAGAMVTVRVDGQRLAVEDNGPGVPAFERESIFKRFYRGESSASRDGS
HHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
GLGLSIVREIARIHGAAVALESTPGGGLTVVVTFPAPALASGPGPASTDSPGRAAESR
CCCHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTGSLRLQITLWLLIPLLGLLAFDAWLTDRRAMSAAHQAFDRTLAASLKSMREGISLRD
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GRVEVEIPNLALEVFDAEDGSRVYYQIRDERGTTITGYEGLPMPEGPVNSLYRTQFYDAE
CEEEEEECCEEEEEEECCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHCCCCH
YLGVPVRMAAMPLPLHDVRSARTQMVWVLLAESTEPREQLASDILVGSLLQELMLISLAL
HCCCCHHHHHCCCCHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIVWLGVRRGLLPLQRLSDAMSARGPDDLEPLEDTALPVEMKPLVAAVNQYVARLHRMIE
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GRKRFFADAAHQLKTPLAIIQAESELALREKDLPSVRAHVERLHGSVQQAAKEVAQLLSL
HHHHHHHHHHHHHHCCHHEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLEPDSGYAPTLRHLRLDTLAQNVALEWAPLARRAGVDLGFEGRGPADIDGQTELLQEL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
LGNLIDNAIRYAGAGAMVTVRVDGQRLAVEDNGPGVPAFERESIFKRFYRGESSASRDGS
HHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
GLGLSIVREIARIHGAAVALESTPGGGLTVVVTFPAPALASGPGPASTDSPGRAAESR
CCCHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]