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The map label for this gene is tctD [H]

Identifier: 94310569

GI number: 94310569

Start: 1755747

End: 1756439

Strand: Reverse

Name: tctD [H]

Synonym: Rmet_1627

Alternate gene names: 94310569

Gene position: 1756439-1755747 (Counterclockwise)

Preceding gene: 94310571

Following gene: 94310568

Centisome position: 44.71

GC content: 65.22

Gene sequence:

>693_bases
ATGCGTATCCTGCTTGCCGAAGACAATCTCAAACTGGCCGAATCGCTGGTGGATTCCCTGAGCCAGAGTGGCTTTGCCGT
CGACTGCATGCATGACGGCGCCAGCGCCGATCATCTGCTGACCACGCAGGACTACGCCCTGGCCATCCTCGACATCGGCA
TGCCCCGCCTGGACGGTCTGGAAGTGCTGCGTCGGCTGCGTCAGCGGCGCAATCCGGTACCAGTGCTGATCCTGACCGCG
CATGGCTCGGTGGAAGACCGCGTGCGCGGGCTGGACCTGGGTGCCGACGACTACCTGGCCAAACCATTCGCGCTGAACGA
ACTGGAGGCCCGGGCGCGCGCGCTGATCCGCCGCAGCCACGGCCATGACCGCACCGCGCTCGAATGCGGCCCGCTGCGCT
ATGACAGCGTGAGCCGTGCCTTCACGCTGCACGGTGAACTGCTGCAACTCACGGGGCGCGAACGCGCCGTGCTGGAAGTG
CTGCTGATGCGCGATGGCCGCGCCGTTAACAAGGCCGCGCTGTCGGAGAAGATTTTCGGCATCGATGAGTCGGTCAATGC
CGACGCCATCGAAATCTACGTCTACCGCCTGCGCAAGAAGCTGGAAGGCAGCGGCGTGAGCATCGTCACGCTGCGCGGGC
TCGGCTATCTGCTGGAATCACGCGACACCGCCACGTCGGACGCGCGCCAATGA

Upstream 100 bases:

>100_bases
TTTCCCTAACTAGGCATACCTGACCCAATGCAGGTATCACTCGTCGCGCGACACTGGTTCGCCCGAGACAAGACTTAGAC
CTGCCCGCTGTATCCCTCCC

Downstream 100 bases:

>100_bases
AAACAGGCAGCCTGAGGCTGCAGATCACGCTCTGGCTGCTGATACCGCTGCTGGGGCTGCTGGCATTCGACGCGTGGCTG
ACCGATCGGCGCGCGATGTC

Product: DNA-binding response regulator in two-component regulatory system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRILLAEDNLKLAESLVDSLSQSGFAVDCMHDGASADHLLTTQDYALAILDIGMPRLDGLEVLRRLRQRRNPVPVLILTA
HGSVEDRVRGLDLGADDYLAKPFALNELEARARALIRRSHGHDRTALECGPLRYDSVSRAFTLHGELLQLTGRERAVLEV
LLMRDGRAVNKAALSEKIFGIDESVNADAIEIYVYRLRKKLEGSGVSIVTLRGLGYLLESRDTATSDARQ

Sequences:

>Translated_230_residues
MRILLAEDNLKLAESLVDSLSQSGFAVDCMHDGASADHLLTTQDYALAILDIGMPRLDGLEVLRRLRQRRNPVPVLILTA
HGSVEDRVRGLDLGADDYLAKPFALNELEARARALIRRSHGHDRTALECGPLRYDSVSRAFTLHGELLQLTGRERAVLEV
LLMRDGRAVNKAALSEKIFGIDESVNADAIEIYVYRLRKKLEGSGVSIVTLRGLGYLLESRDTATSDARQ
>Mature_230_residues
MRILLAEDNLKLAESLVDSLSQSGFAVDCMHDGASADHLLTTQDYALAILDIGMPRLDGLEVLRRLRQRRNPVPVLILTA
HGSVEDRVRGLDLGADDYLAKPFALNELEARARALIRRSHGHDRTALECGPLRYDSVSRAFTLHGELLQLTGRERAVLEV
LLMRDGRAVNKAALSEKIFGIDESVNADAIEIYVYRLRKKLEGSGVSIVTLRGLGYLLESRDTATSDARQ

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=42.6605504587156, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=39.1111111111111, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=40.3669724770642, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=38.9908256880734, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=35.8744394618834, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.5991189427313, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=37.3913043478261, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.8888888888889, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=32.1266968325792, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786911, Length=183, Percent_Identity=34.9726775956284, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=29.0178571428571, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=30.0884955752212, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=29.6943231441048, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=120, Percent_Identity=34.1666666666667, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=31.404958677686, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=25.8620689655172, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787487, Length=129, Percent_Identity=35.6589147286822, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25445; Mature: 25445

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLAEDNLKLAESLVDSLSQSGFAVDCMHDGASADHLLTTQDYALAILDIGMPRLDGL
CEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCHH
EVLRRLRQRRNPVPVLILTAHGSVEDRVRGLDLGADDYLAKPFALNELEARARALIRRSH
HHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GHDRTALECGPLRYDSVSRAFTLHGELLQLTGRERAVLEVLLMRDGRAVNKAALSEKIFG
CCCCCEEEECCCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
IDESVNADAIEIYVYRLRKKLEGSGVSIVTLRGLGYLLESRDTATSDARQ
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRILLAEDNLKLAESLVDSLSQSGFAVDCMHDGASADHLLTTQDYALAILDIGMPRLDGL
CEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEEEECCCCCCCHH
EVLRRLRQRRNPVPVLILTAHGSVEDRVRGLDLGADDYLAKPFALNELEARARALIRRSH
HHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GHDRTALECGPLRYDSVSRAFTLHGELLQLTGRERAVLEVLLMRDGRAVNKAALSEKIFG
CCCCCEEEECCCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
IDESVNADAIEIYVYRLRKKLEGSGVSIVTLRGLGYLLESRDTATSDARQ
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]