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The map label for this gene is cdsA [H]

Identifier: 94310382

GI number: 94310382

Start: 1560659

End: 1561480

Strand: Direct

Name: cdsA [H]

Synonym: Rmet_1440

Alternate gene names: 94310382

Gene position: 1560659-1561480 (Clockwise)

Preceding gene: 94310381

Following gene: 94310383

Centisome position: 39.73

GC content: 66.67

Gene sequence:

>822_bases
ATGCTCCTTACCCGCGTCATCACCGCCGTATGCCTGTTGCTGTTGATCCTGCCGATCCTGTTCCTGGCGCCGCCGGCGGC
ACTGGCGGGGCTGGTCGCCGTCATCGTGCTGCTGGGCGGCTGGGAGTTTGGTCGCCTGATCGGGTTGCGCGGGGCCTGGC
CCTATGTGTACGCAGTAGCTTGCCTGCTGGTCCTGATCGGATGGCATGATGCGCCGCAGCGTGACGCGGTGACGTGGCTG
CTGGAGGCGTCCCTGATTGCCTGGGGTGTGGCACTGGTGCTGATGGCGCGCGGCGTGCGAACTGCCACCCCCGCGTTCAC
GGCGCTAGGGGTCGTTCTGGGGCTGATCATGCTGCCGGCCTTCGGTCACGCCGTCATGGTACTTCGGGCTGCGGGCATTG
GCGTGCTGCTGACGGCTGCCGTGCTGGTCTGGGCCGCCGATATCGGCGCATACTTCGTTGGCAAGGCCATCGGCAAGCGC
AAGCTGGCACCCACGATCAGTCCGGGCAAGTCCTGGGAGGGTGCCATTGGCGGCTGGCTGCTGGCGATGATCGTGGCGCT
CTCGCTGGCCGCGACGCACACGTTCGCCCCAACGTGGTACTCGTTGGTTGCCGACAAGGGCGGGCTGCGCCTCGTGGTTA
TCCTGACCACGCTGCTGGTCGCGGCCAGTATTGTCGGCGACTTGTTCGAGTCGCTGCTCAAGCGCCAGGTCGGCATGAAG
GACAGCAGCCGTCTGCTACCCGGCCATGGCGGGATCCTGGACCGGATCGATGCGTTGATCCCGGTGTTCCCGCTGGCGGC
TCTGCTGCTCGCGTGGATCTGA

Upstream 100 bases:

>100_bases
GCGCTTCGGACGGACCAGCGCGCAGCTGGTGGCGCCAGGCCTGTCCGGTACAGCCTGACGCATCCAACGCCCAACAAACT
CACGGGAACCCACAGCGCAT

Downstream 100 bases:

>100_bases
ACAAATAATCTGATTTCGCATTCCAGCTTCTATGCAACGCATCACCATCCTCGGCGCTACGGGTTCCATCGGCGAGAGCA
CGCTTGACGTGGTTCGGCGC

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLLTRVITAVCLLLLILPILFLAPPAALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVACLLVLIGWHDAPQRDAVTWL
LEASLIAWGVALVLMARGVRTATPAFTALGVVLGLIMLPAFGHAVMVLRAAGIGVLLTAAVLVWAADIGAYFVGKAIGKR
KLAPTISPGKSWEGAIGGWLLAMIVALSLAATHTFAPTWYSLVADKGGLRLVVILTTLLVAASIVGDLFESLLKRQVGMK
DSSRLLPGHGGILDRIDALIPVFPLAALLLAWI

Sequences:

>Translated_273_residues
MLLTRVITAVCLLLLILPILFLAPPAALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVACLLVLIGWHDAPQRDAVTWL
LEASLIAWGVALVLMARGVRTATPAFTALGVVLGLIMLPAFGHAVMVLRAAGIGVLLTAAVLVWAADIGAYFVGKAIGKR
KLAPTISPGKSWEGAIGGWLLAMIVALSLAATHTFAPTWYSLVADKGGLRLVVILTTLLVAASIVGDLFESLLKRQVGMK
DSSRLLPGHGGILDRIDALIPVFPLAALLLAWI
>Mature_273_residues
MLLTRVITAVCLLLLILPILFLAPPAALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVACLLVLIGWHDAPQRDAVTWL
LEASLIAWGVALVLMARGVRTATPAFTALGVVLGLIMLPAFGHAVMVLRAAGIGVLLTAAVLVWAADIGAYFVGKAIGKR
KLAPTISPGKSWEGAIGGWLLAMIVALSLAATHTFAPTWYSLVADKGGLRLVVILTTLLVAASIVGDLFESLLKRQVGMK
DSSRLLPGHGGILDRIDALIPVFPLAALLLAWI

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=289, Percent_Identity=35.6401384083045, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787677, Length=123, Percent_Identity=43.0894308943089, Blast_Score=87, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28697; Mature: 28697

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTRVITAVCLLLLILPILFLAPPAALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVA
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHH
CLLVLIGWHDAPQRDAVTWLLEASLIAWGVALVLMARGVRTATPAFTALGVVLGLIMLPA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FGHAVMVLRAAGIGVLLTAAVLVWAADIGAYFVGKAIGKRKLAPTISPGKSWEGAIGGWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LAMIVALSLAATHTFAPTWYSLVADKGGLRLVVILTTLLVAASIVGDLFESLLKRQVGMK
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSSRLLPGHGGILDRIDALIPVFPLAALLLAWI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLLTRVITAVCLLLLILPILFLAPPAALAGLVAVIVLLGGWEFGRLIGLRGAWPYVYAVA
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHH
CLLVLIGWHDAPQRDAVTWLLEASLIAWGVALVLMARGVRTATPAFTALGVVLGLIMLPA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
FGHAVMVLRAAGIGVLLTAAVLVWAADIGAYFVGKAIGKRKLAPTISPGKSWEGAIGGWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LAMIVALSLAATHTFAPTWYSLVADKGGLRLVVILTTLLVAASIVGDLFESLLKRQVGMK
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSSRLLPGHGGILDRIDALIPVFPLAALLLAWI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]