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The map label for this gene is dadX

Identifier: 94310342

GI number: 94310342

Start: 1509340

End: 1510446

Strand: Direct

Name: dadX

Synonym: Rmet_1400

Alternate gene names: 94310342

Gene position: 1509340-1510446 (Clockwise)

Preceding gene: 94310340

Following gene: 94310343

Centisome position: 38.42

GC content: 66.85

Gene sequence:

>1107_bases
ATGCCAAGACCCATTCAAGCCGTCATCCACCAGCCCGCGCTGGCCAACAATCTTGAGGTGGTGCGTCGCCAAGCACCCGC
ATCCCGCATCTGGGCGGTGGTCAAGGCCAACGCCTACGGCCACGGCATCCGCCGAGTCTTTGCCGGCCTCAAGGCCGCCG
ACGGGTTTGGCCTGCTCGATCTCTCGGAAGCCGTGCTGTTGCGCGACCTTGGGTGGCAGGGCCCGATCCTGCTGCTCGAA
GGCATCTTCCAGGCGCAGGATGTACCGCTGCTCGAGCAATACCGCCTGACCACCGCCGTGCACTGCGAGGAGCAGTTGCG
GATGCTTGAGCTGGCCCGCCCCAAGGGGCCGCTGGCGATCCAGCTCAAGCTGAATACCGGCATGAACCGCCTGGGCTTCC
GTCCGGCGCAGTACCGCGCCGCCTGGGAACGGGCCCGGACCATGTCCTGCATCGGCAGCATTGTCCACATGACGCACTTT
TCCGATGCCGACAGCAAGCGCGGCATTGCGCATCAGGTGGAAGCCTTCGAAGCCGCCACGGCCAACCTGCCGGGGGAGGT
CAGCATGGCCAACTCGGCAGCCGTGCTCTGGCATCCGCAGGCGCATCGCAACTGGGTGCGTCCCGGCATCATCCTTTACG
GCGGATCGCCCACCGGGGTGTCGTCCGATATCGCAGAGACCGGCCTGCAACCGGCGATGTCTCTCCATAGCGAGCTGATC
GGCATACAGGATCTGCAACCGGGCGATACGGTCGGCTATGGTTCCATGTTTACTGCCGACCGCGCGATGCGGGTCGGGGT
GGTGGCGTGCGGCTACGCCGACGGCTACCCACGCCACGCGGTGGGCTGGGGCGAGCGCCGCGCGCCGGTGCTGGTCGACG
GCGTGCGCACGCAATTGGTGGGGCGGGTGTCGATGGACATGATCTGCGTCGACCTGACCCCCTGCCCGAAGGCAAAGGTA
GGCACGCCGGTCACGCTCTGGGGCCATGGTCTGCCAATCGACGACGTGGCCGCCGCCAGCGGCACGGTTGGCTATGAACT
GATGTGCGCGCTGGCGCCGCGCGTGCCGACTTCCGTTGCCACGTTGACCACCGCCGACGCCGTATAA

Upstream 100 bases:

>100_bases
CCGGTGTCCCCATCAACGCACGAATCCCGCAGGTTGCTGACCGGGTCTTCCCTGAAATGGTGCAAGACCGATCCGGCAGC
CGGCCCAAGTTGTCTATTCC

Downstream 100 bases:

>100_bases
ATGGCCAAGACCAAGACGGTATACACATGCACCGAGTGCGGCGGCACCACGCCGCGCTGGGCGGGCCAGTGCCCACAGTG
CAACGCCTGGAACACGCTGG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MPRPIQAVIHQPALANNLEVVRRQAPASRIWAVVKANAYGHGIRRVFAGLKAADGFGLLDLSEAVLLRDLGWQGPILLLE
GIFQAQDVPLLEQYRLTTAVHCEEQLRMLELARPKGPLAIQLKLNTGMNRLGFRPAQYRAAWERARTMSCIGSIVHMTHF
SDADSKRGIAHQVEAFEAATANLPGEVSMANSAAVLWHPQAHRNWVRPGIILYGGSPTGVSSDIAETGLQPAMSLHSELI
GIQDLQPGDTVGYGSMFTADRAMRVGVVACGYADGYPRHAVGWGERRAPVLVDGVRTQLVGRVSMDMICVDLTPCPKAKV
GTPVTLWGHGLPIDDVAAASGTVGYELMCALAPRVPTSVATLTTADAV

Sequences:

>Translated_368_residues
MPRPIQAVIHQPALANNLEVVRRQAPASRIWAVVKANAYGHGIRRVFAGLKAADGFGLLDLSEAVLLRDLGWQGPILLLE
GIFQAQDVPLLEQYRLTTAVHCEEQLRMLELARPKGPLAIQLKLNTGMNRLGFRPAQYRAAWERARTMSCIGSIVHMTHF
SDADSKRGIAHQVEAFEAATANLPGEVSMANSAAVLWHPQAHRNWVRPGIILYGGSPTGVSSDIAETGLQPAMSLHSELI
GIQDLQPGDTVGYGSMFTADRAMRVGVVACGYADGYPRHAVGWGERRAPVLVDGVRTQLVGRVSMDMICVDLTPCPKAKV
GTPVTLWGHGLPIDDVAAASGTVGYELMCALAPRVPTSVATLTTADAV
>Mature_367_residues
PRPIQAVIHQPALANNLEVVRRQAPASRIWAVVKANAYGHGIRRVFAGLKAADGFGLLDLSEAVLLRDLGWQGPILLLEG
IFQAQDVPLLEQYRLTTAVHCEEQLRMLELARPKGPLAIQLKLNTGMNRLGFRPAQYRAAWERARTMSCIGSIVHMTHFS
DADSKRGIAHQVEAFEAATANLPGEVSMANSAAVLWHPQAHRNWVRPGIILYGGSPTGVSSDIAETGLQPAMSLHSELIG
IQDLQPGDTVGYGSMFTADRAMRVGVVACGYADGYPRHAVGWGERRAPVLVDGVRTQLVGRVSMDMICVDLTPCPKAKVG
TPVTLWGHGLPIDDVAAASGTVGYELMCALAPRVPTSVATLTTADAV

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1787439, Length=356, Percent_Identity=57.3033707865169, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1790487, Length=351, Percent_Identity=45.8689458689459, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_RALME (Q1LNJ3)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_583552.1
- ProteinModelPortal:   Q1LNJ3
- SMR:   Q1LNJ3
- STRING:   Q1LNJ3
- GeneID:   4038203
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_1400
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   MCAVAGR
- PhylomeDB:   Q1LNJ3
- ProtClustDB:   PRK00053
- BioCyc:   RMET266264:RMET_1400-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 39528; Mature: 39397

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 35-35 ACT_SITE 253-253

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPIQAVIHQPALANNLEVVRRQAPASRIWAVVKANAYGHGIRRVFAGLKAADGFGLLD
CCCCHHHHHCCCCHHCCHHHHHHHCCHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCCHH
LSEAVLLRDLGWQGPILLLEGIFQAQDVPLLEQYRLTTAVHCEEQLRMLELARPKGPLAI
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
QLKLNTGMNRLGFRPAQYRAAWERARTMSCIGSIVHMTHFSDADSKRGIAHQVEAFEAAT
EEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ANLPGEVSMANSAAVLWHPQAHRNWVRPGIILYGGSPTGVSSDIAETGLQPAMSLHSELI
CCCCCCEEECCCEEEEECCHHHCCCCCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHHC
GIQDLQPGDTVGYGSMFTADRAMRVGVVACGYADGYPRHAVGWGERRAPVLVDGVRTQLV
CCCCCCCCCCCCCCCHHHHCHHHEEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHH
GRVSMDMICVDLTPCPKAKVGTPVTLWGHGLPIDDVAAASGTVGYELMCALAPRVPTSVA
HHHCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHCCCCCCCCE
TLTTADAV
EEEECCCC
>Mature Secondary Structure 
PRPIQAVIHQPALANNLEVVRRQAPASRIWAVVKANAYGHGIRRVFAGLKAADGFGLLD
CCCHHHHHCCCCHHCCHHHHHHHCCHHHEEEEEECCCCHHHHHHHHHHHHCCCCCCCHH
LSEAVLLRDLGWQGPILLLEGIFQAQDVPLLEQYRLTTAVHCEEQLRMLELARPKGPLAI
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
QLKLNTGMNRLGFRPAQYRAAWERARTMSCIGSIVHMTHFSDADSKRGIAHQVEAFEAAT
EEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ANLPGEVSMANSAAVLWHPQAHRNWVRPGIILYGGSPTGVSSDIAETGLQPAMSLHSELI
CCCCCCEEECCCEEEEECCHHHCCCCCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHHC
GIQDLQPGDTVGYGSMFTADRAMRVGVVACGYADGYPRHAVGWGERRAPVLVDGVRTQLV
CCCCCCCCCCCCCCCHHHHCHHHEEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHH
GRVSMDMICVDLTPCPKAKVGTPVTLWGHGLPIDDVAAASGTVGYELMCALAPRVPTSVA
HHHCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHCCCCCCCCE
TLTTADAV
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA