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The map label for this gene is resE [H]

Identifier: 94310119

GI number: 94310119

Start: 1284914

End: 1286428

Strand: Direct

Name: resE [H]

Synonym: Rmet_1174

Alternate gene names: 94310119

Gene position: 1284914-1286428 (Clockwise)

Preceding gene: 94310118

Following gene: 94310121

Centisome position: 32.71

GC content: 67.06

Gene sequence:

>1515_bases
GTGAACCTGTCCCTGACACAACGGCTGTCCGCCGTTTTCGCCGCGTTGTTGCTGGCCTGCTGCGGGGCCTCCGCCTGGCT
GCAGGTGCGGGCCAACGCGATGCATGAGAAAGAGGTGGTCCAGGACATATCGCGCGGGCTCGCCGCATACATCGCGCGCA
ATGCGCTGCTGGAGGATCAGAGCGCCATCGCGCCGCAGGCATTGCGCCAGCTCTTCGGGCAGTTGATGGTCGTGAATCCT
AGTGTTGAGGTCTATCTGCTCGACGATCAGGGGCGCATTCGCGGGCACGATGCGCCGGCCGGCCACCTGGTGCGCGATCA
CGTGAACCTGGCGCCGGTGAAGAAGCTGATCGACGGTGGGGCGCTGCCGATCTTTGGCGACGACCCGCGCAGCGACAGCG
GGCGGAAGGTGTTCAGCGCGGCGCCGTTGCGGCAGGGCGGCTATATCTACGTGGTGCTGCAGGGCGAGGCGCATGACAAG
CTGGCCGCGCTGGCATCGCGCGACGCGGTCATGCGGACCACGCTCTGGTCGATGGCGTTGGTGGCCGCGCTCGGGCTGGT
GGCGGGTCTGGTGGCTTTCGGCCTGATCACGCGCCCGCTGCGACGCCTGACGCTAGAGATCCGGCAATTTGATTCGGGTG
ATGCCGGCGATTTGCGGAGATCCGGCATCCCGGGTGCCGGAGCTGCCGACCGGATACAAGAGCCGATGCAGCGCGACGAG
ATCGCCGCGCTACGCACGGCGTTCCGTCAGATGGCCGACCGGATCGAGACACAATGGCGCGCGCTCAAGCAGCAGGATCA
GGAGCGGCGCGAGATGGTGGCCAATATCTCGCACGACTTGCGCACACCGCTGACGTCGCTGCACGGGTATCTGGAAACGC
TCTCGCTGAAGGCGGACAAGCTCAGCGCCGAGGAACGCCAGCGCTACCTTGCCATCGCGCTGGCGCAGAGCGCCAAGGTG
GGCGGGCTGGCGCAGTCGCTGTTCGAACTGGCGCGGCTCGAACACGGCATGGTCCAGGCGATGCCCGAGACATTCTCGAT
CGTCGACCTGACACAGGACGTGCTCGAGAAATTCGCCCTGCCGGCCGAGGCCAAGCATCTGCAATTGCGCGCCGGCGTGC
CGCCTGTGCTGCCTGCCGTCACCGCCGACCTCGGCATGATCGAACGCGTGCTGACGAACCTGCTCGACAACGCGATTCGC
CATACACCGGTGGGTGGCACTGTCGAAGTCGACCTGACCAGCCAGAATGGCAGCGTGGCGGTGACGGTCAGCGATACGGG
GCCGGGGATTCCGCCGGCCTTGCGCGAGTCGCTGTTCCAGCGGCCGTTTCCATCGGGCGGCGCGCACCGGGGCGGCGGCC
TCGGTCTGCTGATCGTGCAGCGAATGCTCCAGTTGAACGGCAGTCAGGCGCGGCTGGTGGAGGGGCAGGTGGGCACTACG
CTCCGGTTTGTCCTGCCTGTCGCGGGGCGCGAGAGTCGACCGGCGGCAATAGCCGACGCTGCAGCCACGCGATAA

Upstream 100 bases:

>100_bases
ATCCGGCGCAGCCGAAGCGCATCCTGACTGTGTGGCGGCGCGGCTATCGGTTCGTGGCCGATCCGCAAGCCGACGCCGCG
CAGGACGAAGGGGAAGCATC

Downstream 100 bases:

>100_bases
ACACGTCGGCATCGGCCGGCACGTCTCGCGTGGCCGGGACCGCCATCAGACCGCCGCCAAACGCGGTGAATCCGAAGGGT
GCCACGAGGGTGCCTGCTGC

Product: Periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MNLSLTQRLSAVFAALLLACCGASAWLQVRANAMHEKEVVQDISRGLAAYIARNALLEDQSAIAPQALRQLFGQLMVVNP
SVEVYLLDDQGRIRGHDAPAGHLVRDHVNLAPVKKLIDGGALPIFGDDPRSDSGRKVFSAAPLRQGGYIYVVLQGEAHDK
LAALASRDAVMRTTLWSMALVAALGLVAGLVAFGLITRPLRRLTLEIRQFDSGDAGDLRRSGIPGAGAADRIQEPMQRDE
IAALRTAFRQMADRIETQWRALKQQDQERREMVANISHDLRTPLTSLHGYLETLSLKADKLSAEERQRYLAIALAQSAKV
GGLAQSLFELARLEHGMVQAMPETFSIVDLTQDVLEKFALPAEAKHLQLRAGVPPVLPAVTADLGMIERVLTNLLDNAIR
HTPVGGTVEVDLTSQNGSVAVTVSDTGPGIPPALRESLFQRPFPSGGAHRGGGLGLLIVQRMLQLNGSQARLVEGQVGTT
LRFVLPVAGRESRPAAIADAAATR

Sequences:

>Translated_504_residues
MNLSLTQRLSAVFAALLLACCGASAWLQVRANAMHEKEVVQDISRGLAAYIARNALLEDQSAIAPQALRQLFGQLMVVNP
SVEVYLLDDQGRIRGHDAPAGHLVRDHVNLAPVKKLIDGGALPIFGDDPRSDSGRKVFSAAPLRQGGYIYVVLQGEAHDK
LAALASRDAVMRTTLWSMALVAALGLVAGLVAFGLITRPLRRLTLEIRQFDSGDAGDLRRSGIPGAGAADRIQEPMQRDE
IAALRTAFRQMADRIETQWRALKQQDQERREMVANISHDLRTPLTSLHGYLETLSLKADKLSAEERQRYLAIALAQSAKV
GGLAQSLFELARLEHGMVQAMPETFSIVDLTQDVLEKFALPAEAKHLQLRAGVPPVLPAVTADLGMIERVLTNLLDNAIR
HTPVGGTVEVDLTSQNGSVAVTVSDTGPGIPPALRESLFQRPFPSGGAHRGGGLGLLIVQRMLQLNGSQARLVEGQVGTT
LRFVLPVAGRESRPAAIADAAATR
>Mature_504_residues
MNLSLTQRLSAVFAALLLACCGASAWLQVRANAMHEKEVVQDISRGLAAYIARNALLEDQSAIAPQALRQLFGQLMVVNP
SVEVYLLDDQGRIRGHDAPAGHLVRDHVNLAPVKKLIDGGALPIFGDDPRSDSGRKVFSAAPLRQGGYIYVVLQGEAHDK
LAALASRDAVMRTTLWSMALVAALGLVAGLVAFGLITRPLRRLTLEIRQFDSGDAGDLRRSGIPGAGAADRIQEPMQRDE
IAALRTAFRQMADRIETQWRALKQQDQERREMVANISHDLRTPLTSLHGYLETLSLKADKLSAEERQRYLAIALAQSAKV
GGLAQSLFELARLEHGMVQAMPETFSIVDLTQDVLEKFALPAEAKHLQLRAGVPPVLPAVTADLGMIERVLTNLLDNAIR
HTPVGGTVEVDLTSQNGSVAVTVSDTGPGIPPALRESLFQRPFPSGGAHRGGGLGLLIVQRMLQLNGSQARLVEGQVGTT
LRFVLPVAGRESRPAAIADAAATR

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790861, Length=427, Percent_Identity=26.6978922716628, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=26.4957264957265, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=29.1139240506329, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=30.6034482758621, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=503, Percent_Identity=24.4532803180915, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=26.3374485596708, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=27.3109243697479, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=25.609756097561, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=258, Percent_Identity=28.2945736434109, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=339, Percent_Identity=25.9587020648968, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=31.9502074688797, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=349, Percent_Identity=26.9340974212034, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=271, Percent_Identity=23.9852398523985, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=334, Percent_Identity=26.9461077844311, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=211, Percent_Identity=26.0663507109005, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54278; Mature: 54278

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSLTQRLSAVFAALLLACCGASAWLQVRANAMHEKEVVQDISRGLAAYIARNALLEDQ
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SAIAPQALRQLFGQLMVVNPSVEVYLLDDQGRIRGHDAPAGHLVRDHVNLAPVKKLIDGG
HHHHHHHHHHHHHCEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCC
ALPIFGDDPRSDSGRKVFSAAPLRQGGYIYVVLQGEAHDKLAALASRDAVMRTTLWSMAL
CCCCCCCCCCCCCCCEEHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VAALGLVAGLVAFGLITRPLRRLTLEIRQFDSGDAGDLRRSGIPGAGAADRIQEPMQRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHH
IAALRTAFRQMADRIETQWRALKQQDQERREMVANISHDLRTPLTSLHGYLETLSLKADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAEERQRYLAIALAQSAKVGGLAQSLFELARLEHGMVQAMPETFSIVDLTQDVLEKFAL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
PAEAKHLQLRAGVPPVLPAVTADLGMIERVLTNLLDNAIRHTPVGGTVEVDLTSQNGSVA
CCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEE
VTVSDTGPGIPPALRESLFQRPFPSGGAHRGGGLGLLIVQRMLQLNGSQARLVEGQVGTT
EEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCE
LRFVLPVAGRESRPAAIADAAATR
EEEEEECCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MNLSLTQRLSAVFAALLLACCGASAWLQVRANAMHEKEVVQDISRGLAAYIARNALLEDQ
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SAIAPQALRQLFGQLMVVNPSVEVYLLDDQGRIRGHDAPAGHLVRDHVNLAPVKKLIDGG
HHHHHHHHHHHHHCEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCC
ALPIFGDDPRSDSGRKVFSAAPLRQGGYIYVVLQGEAHDKLAALASRDAVMRTTLWSMAL
CCCCCCCCCCCCCCCEEHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
VAALGLVAGLVAFGLITRPLRRLTLEIRQFDSGDAGDLRRSGIPGAGAADRIQEPMQRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHH
IAALRTAFRQMADRIETQWRALKQQDQERREMVANISHDLRTPLTSLHGYLETLSLKADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAEERQRYLAIALAQSAKVGGLAQSLFELARLEHGMVQAMPETFSIVDLTQDVLEKFAL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
PAEAKHLQLRAGVPPVLPAVTADLGMIERVLTNLLDNAIRHTPVGGTVEVDLTSQNGSVA
CCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEE
VTVSDTGPGIPPALRESLFQRPFPSGGAHRGGGLGLLIVQRMLQLNGSQARLVEGQVGTT
EEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCE
LRFVLPVAGRESRPAAIADAAATR
EEEEEECCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]