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The map label for this gene is etfD [C]

Identifier: 94310091

GI number: 94310091

Start: 1255991

End: 1257676

Strand: Reverse

Name: etfD [C]

Synonym: Rmet_1146

Alternate gene names: 94310091

Gene position: 1257676-1255991 (Counterclockwise)

Preceding gene: 94310097

Following gene: 94310086

Centisome position: 32.02

GC content: 63.35

Gene sequence:

>1686_bases
ATGGATCAGCAACAGCTCGTCGAGCAGTTCGGCCCGCGAGAAGCCATGGAGTACGACGTCGTCATCGTTGGCGGCGGACC
TGCAGGCCTCGCCACGGCTATTCGCCTGAAGCAACTGGCGCAAGAAAAAGGCGGCGACGTCAATGTCTGTGTGCTGGAGA
AGGGCTCGGAGCCCGGCGCTCACATCCTGTCCGGCGCGATCATGGATCCGCGCGCGCTCACTGAACTGATCCCGAACTGG
AAGGAACTCGGCGCGCCGCTGAACCAGCCGGTAACAGAAGACAAGTTCCTGTTCCTGAACGAATCCGGCTCCAAGGGCAC
CCCGCCGGCGCTGCTGCCGGAGTGCTTCCACAACCACGGCAACTACATCGTCAGCCTGTCGAACTTCGTGCGCTGGATGG
GCCAGCAGGCCGAGGCCCTGGGCGTGGAAATTTTCCCGGGCTTCCCGGCCGCCGAAGTCCTGTACAACGAGGACGGCTCG
GTCAAGGGCGTTGCCACGGGCAACATGGGTATCAGCAAGGAAGGCGAGCCCACCGAGAACTTCCAGCTCGGCATGGAGCT
CCACGCCAAGTACACGATCTTCGCCGAGGGCGCGCGTGGCCACCTGGGCAAGCAGATCATCGCCAAGTACAAGCTCGACG
CCGGCAAGGACCCGCAAAGCTACGGCATTGGCCTGAAGGAACTGTGGGAAATCGATCCGGCCAAGCATAAGCCCGGTCTG
GTGGTGCACACGGCTGGCTGGCCGCTCGACCCGGCAACCTACGGCGGCTCGTTCCTCTATCACATGGAGGACAACAAGGT
CGCAGTGGGCTTCGTGGTTGGCCTGGACTACACGAACCCGTGGCTGTCGCCGTTCGAGGAATTCCAGCGCTTCAAGACGC
ACCCGGAAATCCGCGCTTACTTTGAAGGCGGCAAGCGAATCGGCTATGGCGCCCGCGCGATCACCGCCGGCGGCCTGCTG
TCGCTGCCGAAGACCGTGTTCCCGGGTGGCGCGCTGGTGGGTTGCGACGCCGGCTACCTGAACGCCTCGCGTATCAAGGG
AAGCCACGCTGCGATCAAGACTGGCATGCTGGCCGCCGAGGCCGCCTACGACGCGCTGCAGGGCGGCCGTCAGCACGACG
AACTGACCGCCTACCCCGCCGCGTTCGAATCGAGCTGGCTCCACAAGGAACTGCTGCAAGCGAAGAACTTCAAGCAGTGG
TTCAAGAAGGGCCGCACTACCGCCACGCTGATGACCGGTATCGAGCAATGGCTGCTGCCGAAGCTGGGCATCCGCAACCC
GCCCTGGACCCTCCACCGCGAAAAGCCGGATCACGTGTACCTGAAGCCGGCCGCCGAATGCGAGAAGATCGTCTATCCGA
AGCCGGACGGCAAGCTCACGTTCGATCGTCTCTCGTCAGTGTTCATCAGCAACACGAACCACGAAGAAAACCAGCCCGCG
CACCTGACGCTCAAGGACGCGAACGTGCCGGTGAACATCAACTGGGAAAAGTACGCCGGCCCCGAGTCGCGCTACTGCCC
GGCTGGCGTGTACGAGTTCGTGCAGAACGATGACGGCAAGGAGCGCCTGCAGATCAACGCGCAGAACTGCGTGCACTGCA
AGACGTGCGACATCAAGGACCCGACGCAGAACATCGTGTGGGTCACGCCGGAAGGCGGCGGCGGCCCGAACTACGTGGGC
ATGTAA

Upstream 100 bases:

>100_bases
GAGCCCGGTCACCGCATTCCCACAAACCGCAGCACCCGCACGACGGACTGCGACCCATGCGGCAGTATTGCCGCCCAGAA
GAAACAGAGGGTAAGAGACA

Downstream 100 bases:

>100_bases
TACGCTGCCGCCCGAGACAGGATCAGGCGGCATTGCAGGACAAGGAAAACGCCGGCCAATGGCCGGCGTTTTCTATTGGG
CGAACCTTCTTTTGGGCGAA

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MDQQQLVEQFGPREAMEYDVVIVGGGPAGLATAIRLKQLAQEKGGDVNVCVLEKGSEPGAHILSGAIMDPRALTELIPNW
KELGAPLNQPVTEDKFLFLNESGSKGTPPALLPECFHNHGNYIVSLSNFVRWMGQQAEALGVEIFPGFPAAEVLYNEDGS
VKGVATGNMGISKEGEPTENFQLGMELHAKYTIFAEGARGHLGKQIIAKYKLDAGKDPQSYGIGLKELWEIDPAKHKPGL
VVHTAGWPLDPATYGGSFLYHMEDNKVAVGFVVGLDYTNPWLSPFEEFQRFKTHPEIRAYFEGGKRIGYGARAITAGGLL
SLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKTGMLAAEAAYDALQGGRQHDELTAYPAAFESSWLHKELLQAKNFKQW
FKKGRTTATLMTGIEQWLLPKLGIRNPPWTLHREKPDHVYLKPAAECEKIVYPKPDGKLTFDRLSSVFISNTNHEENQPA
HLTLKDANVPVNINWEKYAGPESRYCPAGVYEFVQNDDGKERLQINAQNCVHCKTCDIKDPTQNIVWVTPEGGGGPNYVG
M

Sequences:

>Translated_561_residues
MDQQQLVEQFGPREAMEYDVVIVGGGPAGLATAIRLKQLAQEKGGDVNVCVLEKGSEPGAHILSGAIMDPRALTELIPNW
KELGAPLNQPVTEDKFLFLNESGSKGTPPALLPECFHNHGNYIVSLSNFVRWMGQQAEALGVEIFPGFPAAEVLYNEDGS
VKGVATGNMGISKEGEPTENFQLGMELHAKYTIFAEGARGHLGKQIIAKYKLDAGKDPQSYGIGLKELWEIDPAKHKPGL
VVHTAGWPLDPATYGGSFLYHMEDNKVAVGFVVGLDYTNPWLSPFEEFQRFKTHPEIRAYFEGGKRIGYGARAITAGGLL
SLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKTGMLAAEAAYDALQGGRQHDELTAYPAAFESSWLHKELLQAKNFKQW
FKKGRTTATLMTGIEQWLLPKLGIRNPPWTLHREKPDHVYLKPAAECEKIVYPKPDGKLTFDRLSSVFISNTNHEENQPA
HLTLKDANVPVNINWEKYAGPESRYCPAGVYEFVQNDDGKERLQINAQNCVHCKTCDIKDPTQNIVWVTPEGGGGPNYVG
M
>Mature_561_residues
MDQQQLVEQFGPREAMEYDVVIVGGGPAGLATAIRLKQLAQEKGGDVNVCVLEKGSEPGAHILSGAIMDPRALTELIPNW
KELGAPLNQPVTEDKFLFLNESGSKGTPPALLPECFHNHGNYIVSLSNFVRWMGQQAEALGVEIFPGFPAAEVLYNEDGS
VKGVATGNMGISKEGEPTENFQLGMELHAKYTIFAEGARGHLGKQIIAKYKLDAGKDPQSYGIGLKELWEIDPAKHKPGL
VVHTAGWPLDPATYGGSFLYHMEDNKVAVGFVVGLDYTNPWLSPFEEFQRFKTHPEIRAYFEGGKRIGYGARAITAGGLL
SLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKTGMLAAEAAYDALQGGRQHDELTAYPAAFESSWLHKELLQAKNFKQW
FKKGRTTATLMTGIEQWLLPKLGIRNPPWTLHREKPDHVYLKPAAECEKIVYPKPDGKLTFDRLSSVFISNTNHEENQPA
HLTLKDANVPVNINWEKYAGPESRYCPAGVYEFVQNDDGKERLQINAQNCVHCKTCDIKDPTQNIVWVTPEGGGGPNYVG
M

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=560, Percent_Identity=56.6071428571429, Blast_Score=621, Evalue=1e-178,
Organism=Escherichia coli, GI1787991, Length=339, Percent_Identity=27.7286135693215, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786227, Length=330, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082155, Length=385, Percent_Identity=26.2337662337662, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25144720, Length=561, Percent_Identity=56.50623885918, Blast_Score=619, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6324932, Length=590, Percent_Identity=44.0677966101695, Blast_Score=470, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24652256, Length=558, Percent_Identity=59.1397849462366, Blast_Score=650, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 61513; Mature: 61513

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQQQLVEQFGPREAMEYDVVIVGGGPAGLATAIRLKQLAQEKGGDVNVCVLEKGSEPGA
CCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
HILSGAIMDPRALTELIPNWKELGAPLNQPVTEDKFLFLNESGSKGTPPALLPECFHNHG
HHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCC
NYIVSLSNFVRWMGQQAEALGVEIFPGFPAAEVLYNEDGSVKGVATGNMGISKEGEPTEN
CEEEEHHHHHHHHCCCCHHCCEEEECCCCHHHEEECCCCCEEEEEECCCCCCCCCCCCCC
FQLGMELHAKYTIFAEGARGHLGKQIIAKYKLDAGKDPQSYGIGLKELWEIDPAKHKPGL
EEECEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHCCCCCCCCCCE
VVHTAGWPLDPATYGGSFLYHMEDNKVAVGFVVGLDYTNPWLSPFEEFQRFKTHPEIRAY
EEEECCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHE
FEGGKRIGYGARAITAGGLLSLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKTGMLAAE
ECCCCEECCCCCEEECCCCHHCCHHHCCCCEEEECCCCCCCHHHCCCCHHHHHHHHHHHH
AAYDALQGGRQHDELTAYPAAFESSWLHKELLQAKNFKQWFKKGRTTATLMTGIEQWLLP
HHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHH
KLGIRNPPWTLHREKPDHVYLKPAAECEKIVYPKPDGKLTFDRLSSVFISNTNHEENQPA
HCCCCCCCCCCCCCCCCEEEECCHHHHCCEECCCCCCCEEHHHHHHHEEECCCCCCCCCC
HLTLKDANVPVNINWEKYAGPESRYCPAGVYEFVQNDDGKERLQINAQNCVHCKTCDIKD
EEEEECCCCCEEECHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCC
PTQNIVWVTPEGGGGPNYVGM
CCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDQQQLVEQFGPREAMEYDVVIVGGGPAGLATAIRLKQLAQEKGGDVNVCVLEKGSEPGA
CCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
HILSGAIMDPRALTELIPNWKELGAPLNQPVTEDKFLFLNESGSKGTPPALLPECFHNHG
HHHHCCCCCHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCC
NYIVSLSNFVRWMGQQAEALGVEIFPGFPAAEVLYNEDGSVKGVATGNMGISKEGEPTEN
CEEEEHHHHHHHHCCCCHHCCEEEECCCCHHHEEECCCCCEEEEEECCCCCCCCCCCCCC
FQLGMELHAKYTIFAEGARGHLGKQIIAKYKLDAGKDPQSYGIGLKELWEIDPAKHKPGL
EEECEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHCCCCCCCCCCE
VVHTAGWPLDPATYGGSFLYHMEDNKVAVGFVVGLDYTNPWLSPFEEFQRFKTHPEIRAY
EEEECCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHE
FEGGKRIGYGARAITAGGLLSLPKTVFPGGALVGCDAGYLNASRIKGSHAAIKTGMLAAE
ECCCCEECCCCCEEECCCCHHCCHHHCCCCEEEECCCCCCCHHHCCCCHHHHHHHHHHHH
AAYDALQGGRQHDELTAYPAAFESSWLHKELLQAKNFKQWFKKGRTTATLMTGIEQWLLP
HHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHH
KLGIRNPPWTLHREKPDHVYLKPAAECEKIVYPKPDGKLTFDRLSSVFISNTNHEENQPA
HCCCCCCCCCCCCCCCCEEEECCHHHHCCEECCCCCCCEEHHHHHHHEEECCCCCCCCCC
HLTLKDANVPVNINWEKYAGPESRYCPAGVYEFVQNDDGKERLQINAQNCVHCKTCDIKD
EEEEECCCCCEEECHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCC
PTQNIVWVTPEGGGGPNYVGM
CCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]