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The map label for this gene is uxuR [H]

Identifier: 94310086

GI number: 94310086

Start: 1248642

End: 1249343

Strand: Reverse

Name: uxuR [H]

Synonym: Rmet_1141

Alternate gene names: 94310086

Gene position: 1249343-1248642 (Counterclockwise)

Preceding gene: 94310091

Following gene: 94310085

Centisome position: 31.81

GC content: 70.09

Gene sequence:

>702_bases
ATGAATCGTCTCTCCCGCCCCGCCTCCCTCGCCAGCCGCATCGCCCAGGCCCTGCGCGACGATATCGCCGCCGGACGCTT
TGCGGCTGGCGCCCGGTTGCCGGCCGAGGCCACGCTGGCGGAGACGTTCGATGTAAGCCGGCCGATCGTGCGCGAAGCCA
TCGCCCTGCTGAAGGCCGACGGGATACTGGTCACTCGCAAGGGGTCCGGCGCCTATGTCTCGGAGACACCAGGCGGGCAA
GTCTGGCGCGTAGCCAGCGCCCCGGACGGTGGTCCGACGCTGGCTCAGCTATTCGAATTACGGCGCGTAGTGGAAACCGC
GTGCGCCGAAATGGCGGCCGCACGCCGCACCGATGTCGATCTGGTCGCGATCCGTGCCGCACTGGCCACGATGCAGACCC
ACGCCACAGACTTCCCGAGCGCGGCTGCCGCCGACATTGCGTTCCACCACGCAATTGCCCAGGCCGCCCACAACCCCTGC
TTTACCGGGCTAACGGATTTTGTCAGCCAGCAATTGCTCGTGGCGCGCCAGCACGCCTGGGAGAACAGCGCCCGCCTCGG
CACGTTGCATGGCACACCACGCGCCGCCGACGCCGAACATGCGGCCCTGGTCGAGGCCATCGCGGCCGGCGACCCCTCGA
CGGCCCGTGCGGCGGCCACCGCCCACCTGTCCGCCGCCGCTGCGCGGATGGGCCTCGACTGA

Upstream 100 bases:

>100_bases
CTGTAGCGCACGGGCAGCTTGCCGCTTGACGCGGCTCAATCATCGCTGCAGAATCAGCCACTTGCGCAAAGCTGTCTGAC
AGCCTGACATATCAATTCCA

Downstream 100 bases:

>100_bases
ACAACAGATATCAGAGCAACAAGGAGCAGAGAGATGGAACAAGTAGATTGCGTCGTGATCGGCGCTGGCGTGGTCGGTCT
GGCCGTTGCGCGCGCGCTGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNRLSRPASLASRIAQALRDDIAAGRFAAGARLPAEATLAETFDVSRPIVREAIALLKADGILVTRKGSGAYVSETPGGQ
VWRVASAPDGGPTLAQLFELRRVVETACAEMAAARRTDVDLVAIRAALATMQTHATDFPSAAAADIAFHHAIAQAAHNPC
FTGLTDFVSQQLLVARQHAWENSARLGTLHGTPRAADAEHAALVEAIAAGDPSTARAAATAHLSAAAARMGLD

Sequences:

>Translated_233_residues
MNRLSRPASLASRIAQALRDDIAAGRFAAGARLPAEATLAETFDVSRPIVREAIALLKADGILVTRKGSGAYVSETPGGQ
VWRVASAPDGGPTLAQLFELRRVVETACAEMAAARRTDVDLVAIRAALATMQTHATDFPSAAAADIAFHHAIAQAAHNPC
FTGLTDFVSQQLLVARQHAWENSARLGTLHGTPRAADAEHAALVEAIAAGDPSTARAAATAHLSAAAARMGLD
>Mature_233_residues
MNRLSRPASLASRIAQALRDDIAAGRFAAGARLPAEATLAETFDVSRPIVREAIALLKADGILVTRKGSGAYVSETPGGQ
VWRVASAPDGGPTLAQLFELRRVVETACAEMAAARRTDVDLVAIRAALATMQTHATDFPSAAAADIAFHHAIAQAAHNPC
FTGLTDFVSQQLLVARQHAWENSARLGTLHGTPRAADAEHAALVEAIAAGDPSTARAAATAHLSAAAARMGLD

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=226, Percent_Identity=31.858407079646, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790780, Length=230, Percent_Identity=30, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786303, Length=226, Percent_Identity=31.4159292035398, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790032, Length=229, Percent_Identity=32.3144104803493, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87082208, Length=232, Percent_Identity=28.8793103448276, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789621, Length=238, Percent_Identity=28.9915966386555, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789353, Length=239, Percent_Identity=26.3598326359833, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24186; Mature: 24186

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLSRPASLASRIAQALRDDIAAGRFAAGARLPAEATLAETFDVSRPIVREAIALLKAD
CCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCC
GILVTRKGSGAYVSETPGGQVWRVASAPDGGPTLAQLFELRRVVETACAEMAAARRTDVD
CEEEEECCCCCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVAIRAALATMQTHATDFPSAAAADIAFHHAIAQAAHNPCFTGLTDFVSQQLLVARQHAW
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
ENSARLGTLHGTPRAADAEHAALVEAIAAGDPSTARAAATAHLSAAAARMGLD
CCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRLSRPASLASRIAQALRDDIAAGRFAAGARLPAEATLAETFDVSRPIVREAIALLKAD
CCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCC
GILVTRKGSGAYVSETPGGQVWRVASAPDGGPTLAQLFELRRVVETACAEMAAARRTDVD
CEEEEECCCCCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LVAIRAALATMQTHATDFPSAAAADIAFHHAIAQAAHNPCFTGLTDFVSQQLLVARQHAW
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
ENSARLGTLHGTPRAADAEHAALVEAIAAGDPSTARAAATAHLSAAAARMGLD
CCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]