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The map label for this gene is cysS [H]

Identifier: 94310045

GI number: 94310045

Start: 1197120

End: 1198538

Strand: Direct

Name: cysS [H]

Synonym: Rmet_1100

Alternate gene names: 94310045

Gene position: 1197120-1198538 (Clockwise)

Preceding gene: 94310044

Following gene: 94310046

Centisome position: 30.48

GC content: 62.51

Gene sequence:

>1419_bases
ATGACTTCCGCGCTCAGCCTCTACAACTCGCTGACCCGCAAGAAGGAGCCCTTGCGGACCGGGCAGCCGGGCCGCGTCAC
GATGTATGTCTGCGGGCCAACGGTCTACAACTTCGCGCATATCGGCAATGCCAGGCCGGCCGTTGTCTTCGACGTGCTGG
CGCGGCTACTGCGCGAGCAATACGCAGAAGTGGTCTACGCCCGCAACTTCACCGATGTGGATGACAAGATCAACGCGAGC
GCGGCGGCGGAGGGCGTACCTATCGGCACCATTACAGCGCGCTATATCGATGCCTACCACGAAGACATGCGCGCGCTGGG
CGTGTTGATTCCTGACCTGGAGCCGCGCGTCACCGAGCACATCCCCGCGATCATTGCGTTGATACAGCGGCTGATCGCAA
ATGGGAATGCCTATGTCGAACAGGATCATGTCCTGTTTCACGTGCCGTCCTTTCCCGCGTATGGCCAACTTTCGGGTCGC
CGACCTGAGGACATGCTTGCCGGCGTGCGTGTCGACGTCGCACCGTACAAGCGCGATCCGCTGGACTTTGTCCTCTGGAA
GCCGTCCACTGCCGAGGTTCCGGGCTGGCCGAGTCCGTGGGGACGCGGGCGACCAGGTTGGCATATCGAATGCTCAGCCA
TGATCGGGCAACACCTGGGAAGCACGATCGACATCCACGGGGGTGGTCAGGATCTGATATTCCCGCATCACGAGAATGAG
ATTGCCCAGGGCACTTGCGCGAATGGCGAGTTGTACTGCCGCACCTGGGTTCACAACAGCTTCGTTACCGTGGACGGTCA
GAAGATGTCCAAGTCGCTCGGCAACGTTCTGCTGCTGCGCGATCTGCTGGGTCAGGCGCCGGGGGAAGCGATACGACTGG
CGCTGCTTTCGGCGCATTACCGGCATCCTCTCGACTGGAACGCGCAGCGTCTGTTGACGGCGCGCCAGACGCTGTTGCGC
TTCTACCGGGGGCTGAAGATGGCCGAACACATCGAGATCTCGCCCGGCGAAGAGCCCGACGAGGAGGTAATCGCGGCTCT
CAACAATGATCTGAACATTCCGGGTGCGCTGGCGCGACTCCACGTGTTGCTCGCCGAGTTGGAAAAGGCAGGTGCTGATG
CCAGCCGATCCGTGGCCAAGGCACGGATGATGGCGTCGGGACGGTTGCTCGGATTGTTCCAGCAGGATCCAAACTCCGCG
CTCCGGGGACTGGCCGGGGCAGCAGTCACCCATGGAATCGCCACTACTGCGGACGCGGCACGGATCGACCATCTGGTCGC
GGAGCGCGAGCAGGCCCGCAAGCGCCGCGACTTCGCACGGGCAGACGCACTGCGTGAGGAACTTGGCGCGGCCGGTGTCC
TGGTTCACGACACGCCCAATGGGAGTACCTGGACCCTTGTCGATGGAACTCCAGCATAA

Upstream 100 bases:

>100_bases
ATCCCAGAGTTCACGTTCGGCACCTTGAGAGTCTCCATCCTCATGATGCGGTGGCTTGGGCGGCGCCGTTGCAGATGAAG
CATTCACGGGAGGTGGCCGC

Downstream 100 bases:

>100_bases
GGGCGGCGGGTGTCATGTGACGAAGCCATGCTGATTCGCAAGCTCTTCCGCTTCGAGAACGCCCATATCGTGCGCGGATG
CAGCACGAGGCGCTGCTCGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTSALSLYNSLTRKKEPLRTGQPGRVTMYVCGPTVYNFAHIGNARPAVVFDVLARLLREQYAEVVYARNFTDVDDKINAS
AAAEGVPIGTITARYIDAYHEDMRALGVLIPDLEPRVTEHIPAIIALIQRLIANGNAYVEQDHVLFHVPSFPAYGQLSGR
RPEDMLAGVRVDVAPYKRDPLDFVLWKPSTAEVPGWPSPWGRGRPGWHIECSAMIGQHLGSTIDIHGGGQDLIFPHHENE
IAQGTCANGELYCRTWVHNSFVTVDGQKMSKSLGNVLLLRDLLGQAPGEAIRLALLSAHYRHPLDWNAQRLLTARQTLLR
FYRGLKMAEHIEISPGEEPDEEVIAALNNDLNIPGALARLHVLLAELEKAGADASRSVAKARMMASGRLLGLFQQDPNSA
LRGLAGAAVTHGIATTADAARIDHLVAEREQARKRRDFARADALREELGAAGVLVHDTPNGSTWTLVDGTPA

Sequences:

>Translated_472_residues
MTSALSLYNSLTRKKEPLRTGQPGRVTMYVCGPTVYNFAHIGNARPAVVFDVLARLLREQYAEVVYARNFTDVDDKINAS
AAAEGVPIGTITARYIDAYHEDMRALGVLIPDLEPRVTEHIPAIIALIQRLIANGNAYVEQDHVLFHVPSFPAYGQLSGR
RPEDMLAGVRVDVAPYKRDPLDFVLWKPSTAEVPGWPSPWGRGRPGWHIECSAMIGQHLGSTIDIHGGGQDLIFPHHENE
IAQGTCANGELYCRTWVHNSFVTVDGQKMSKSLGNVLLLRDLLGQAPGEAIRLALLSAHYRHPLDWNAQRLLTARQTLLR
FYRGLKMAEHIEISPGEEPDEEVIAALNNDLNIPGALARLHVLLAELEKAGADASRSVAKARMMASGRLLGLFQQDPNSA
LRGLAGAAVTHGIATTADAARIDHLVAEREQARKRRDFARADALREELGAAGVLVHDTPNGSTWTLVDGTPA
>Mature_471_residues
TSALSLYNSLTRKKEPLRTGQPGRVTMYVCGPTVYNFAHIGNARPAVVFDVLARLLREQYAEVVYARNFTDVDDKINASA
AAEGVPIGTITARYIDAYHEDMRALGVLIPDLEPRVTEHIPAIIALIQRLIANGNAYVEQDHVLFHVPSFPAYGQLSGRR
PEDMLAGVRVDVAPYKRDPLDFVLWKPSTAEVPGWPSPWGRGRPGWHIECSAMIGQHLGSTIDIHGGGQDLIFPHHENEI
AQGTCANGELYCRTWVHNSFVTVDGQKMSKSLGNVLLLRDLLGQAPGEAIRLALLSAHYRHPLDWNAQRLLTARQTLLRF
YRGLKMAEHIEISPGEEPDEEVIAALNNDLNIPGALARLHVLLAELEKAGADASRSVAKARMMASGRLLGLFQQDPNSAL
RGLAGAAVTHGIATTADAARIDHLVAEREQARKRRDFARADALREELGAAGVLVHDTPNGSTWTLVDGTPA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=316, Percent_Identity=40.5063291139241, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI10835051, Length=232, Percent_Identity=40.948275862069, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI62240992, Length=232, Percent_Identity=40.948275862069, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI21269877, Length=232, Percent_Identity=40.948275862069, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI303304987, Length=232, Percent_Identity=40.948275862069, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1786737, Length=468, Percent_Identity=44.8717948717949, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17509795, Length=242, Percent_Identity=36.7768595041322, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17509797, Length=242, Percent_Identity=36.7768595041322, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324082, Length=307, Percent_Identity=34.2019543973941, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI19922218, Length=328, Percent_Identity=42.0731707317073, Blast_Score=238, Evalue=6e-63,
Organism=Drosophila melanogaster, GI19922364, Length=283, Percent_Identity=37.8091872791519, Blast_Score=185, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51648; Mature: 51517

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSALSLYNSLTRKKEPLRTGQPGRVTMYVCGPTVYNFAHIGNARPAVVFDVLARLLREQ
CCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHH
YAEVVYARNFTDVDDKINASAAAEGVPIGTITARYIDAYHEDMRALGVLIPDLEPRVTEH
HHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IPAIIALIQRLIANGNAYVEQDHVLFHVPSFPAYGQLSGRRPEDMLAGVRVDVAPYKRDP
HHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCC
LDFVLWKPSTAEVPGWPSPWGRGRPGWHIECSAMIGQHLGSTIDIHGGGQDLIFPHHENE
CCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEECCCCCCEECCCCCCC
IAQGTCANGELYCRTWVHNSFVTVDGQKMSKSLGNVLLLRDLLGQAPGEAIRLALLSAHY
CCCCCCCCCCEEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RHPLDWNAQRLLTARQTLLRFYRGLKMAEHIEISPGEEPDEEVIAALNNDLNIPGALARL
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHCCCCCCCHHHHHH
HVLLAELEKAGADASRSVAKARMMASGRLLGLFQQDPNSALRGLAGAAVTHGIATTADAA
HHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHH
RIDHLVAEREQARKRRDFARADALREELGAAGVLVHDTPNGSTWTLVDGTPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCC
>Mature Secondary Structure 
TSALSLYNSLTRKKEPLRTGQPGRVTMYVCGPTVYNFAHIGNARPAVVFDVLARLLREQ
CHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHH
YAEVVYARNFTDVDDKINASAAAEGVPIGTITARYIDAYHEDMRALGVLIPDLEPRVTEH
HHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IPAIIALIQRLIANGNAYVEQDHVLFHVPSFPAYGQLSGRRPEDMLAGVRVDVAPYKRDP
HHHHHHHHHHHHHCCCCEEECCCEEEECCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCC
LDFVLWKPSTAEVPGWPSPWGRGRPGWHIECSAMIGQHLGSTIDIHGGGQDLIFPHHENE
CCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEECCCCCCEECCCCCCC
IAQGTCANGELYCRTWVHNSFVTVDGQKMSKSLGNVLLLRDLLGQAPGEAIRLALLSAHY
CCCCCCCCCCEEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RHPLDWNAQRLLTARQTLLRFYRGLKMAEHIEISPGEEPDEEVIAALNNDLNIPGALARL
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCHHHHHHHHCCCCCCCHHHHHH
HVLLAELEKAGADASRSVAKARMMASGRLLGLFQQDPNSALRGLAGAAVTHGIATTADAA
HHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHH
RIDHLVAEREQARKRRDFARADALREELGAAGVLVHDTPNGSTWTLVDGTPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA