Click here to switch to the map view.

The map label for this gene is folE2-1 [H]

Identifier: 94310044

GI number: 94310044

Start: 1196149

End: 1197123

Strand: Direct

Name: folE2-1 [H]

Synonym: Rmet_1099

Alternate gene names: 94310044

Gene position: 1196149-1197123 (Clockwise)

Preceding gene: 94310043

Following gene: 94310045

Centisome position: 30.45

GC content: 62.97

Gene sequence:

>975_bases
ATGCGCCCAGGACATTGGGGATGCCTTCCCAATCCGAACGAAAGCATGAGCGCAGCCCTTCCCGACGTTTCCCTGACCGA
AGCCTCCCCGACCTTCACCCCGCTCGAGTGGGTCGGCATGCAGGGCATTGACCTGCCAATCAGGCTTGTCGAGCCTGGCT
ATCGGCGTCAGTTGCATGCCCGCGCGGACATTCATGTCGACCTGCCCGCGCCCAGGGTCAAGGGGATCCATATGTCTCGC
CTGTACGCGCTGCTTGATGCGCTGGACGACGGCGAGGGGCTTTCGCCCATCCGCATACGGCAGTTGCTTGAAGCGATGGT
GGACAGTCATCGCGATTGCGAGACAGGCAGCGCGCGGCTACGCCTGCGTTTTGATCTGCTAGTCCGTCGCCCCGCATTGG
TCACGGAAGGCATTGCAGGATGGAAGTCGTATCCGGTGCGGTTGGACGCATCGCTGGTCGGCAATGTCTTTGCGCTGACG
GCTCGGATCACGGCAGGCTACTCGTCGACTTGCCCGTGCTCCGCGGCGTTGACCCGGCAACTGGTAGAGCAAGGGTTTGC
GAAGGCGTTCGCGCATGAGCGTCGAGTCGACGTCGCCAGAGTCTCGGCCTGGTTGCGGCAACACGGCACGCTGGCGACGC
CGCACAGCCAGCGCAGTGAGGCGTCGATCACCGTGGACATTGCCGTCGATTTGCCGAACCTGGGGCTTCTCGACCTGGTC
GACCACATCGAGCGCGCGCTGGGCACGCCAGTACAGACTGCCGTCAAGCGCGCCGATGAGCAGGCATTCGCTGCGCTGAA
TGGCCAGAATCTCATGTTCGTTGAAGACGCGGCGCGCCGCATTCAGGTTGCGTTGGACGGACGTTTCGCGAATCCCAGAG
TTCACGTTCGGCACCTTGAGAGTCTCCATCCTCATGATGCGGTGGCTTGGGCGGCGCCGTTGCAGATGAAGCATTCACGG
GAGGTGGCCGCATGA

Upstream 100 bases:

>100_bases
CGCCTGCCTGTTGACGGACGACGAGATGGCGCAGGGTCCCGATGTGTGGACCACCTGGCACAACCCCTTTCCTGACTGGC
CCTGACACTTTGGGCTCCCC

Downstream 100 bases:

>100_bases
CTTCCGCGCTCAGCCTCTACAACTCGCTGACCCGCAAGAAGGAGCCCTTGCGGACCGGGCAGCCGGGCCGCGTCACGATG
TATGTCTGCGGGCCAACGGT

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRPGHWGCLPNPNESMSAALPDVSLTEASPTFTPLEWVGMQGIDLPIRLVEPGYRRQLHARADIHVDLPAPRVKGIHMSR
LYALLDALDDGEGLSPIRIRQLLEAMVDSHRDCETGSARLRLRFDLLVRRPALVTEGIAGWKSYPVRLDASLVGNVFALT
ARITAGYSSTCPCSAALTRQLVEQGFAKAFAHERRVDVARVSAWLRQHGTLATPHSQRSEASITVDIAVDLPNLGLLDLV
DHIERALGTPVQTAVKRADEQAFAALNGQNLMFVEDAARRIQVALDGRFANPRVHVRHLESLHPHDAVAWAAPLQMKHSR
EVAA

Sequences:

>Translated_324_residues
MRPGHWGCLPNPNESMSAALPDVSLTEASPTFTPLEWVGMQGIDLPIRLVEPGYRRQLHARADIHVDLPAPRVKGIHMSR
LYALLDALDDGEGLSPIRIRQLLEAMVDSHRDCETGSARLRLRFDLLVRRPALVTEGIAGWKSYPVRLDASLVGNVFALT
ARITAGYSSTCPCSAALTRQLVEQGFAKAFAHERRVDVARVSAWLRQHGTLATPHSQRSEASITVDIAVDLPNLGLLDLV
DHIERALGTPVQTAVKRADEQAFAALNGQNLMFVEDAARRIQVALDGRFANPRVHVRHLESLHPHDAVAWAAPLQMKHSR
EVAA
>Mature_324_residues
MRPGHWGCLPNPNESMSAALPDVSLTEASPTFTPLEWVGMQGIDLPIRLVEPGYRRQLHARADIHVDLPAPRVKGIHMSR
LYALLDALDDGEGLSPIRIRQLLEAMVDSHRDCETGSARLRLRFDLLVRRPALVTEGIAGWKSYPVRLDASLVGNVFALT
ARITAGYSSTCPCSAALTRQLVEQGFAKAFAHERRVDVARVSAWLRQHGTLATPHSQRSEASITVDIAVDLPNLGLLDLV
DHIERALGTPVQTAVKRADEQAFAALNGQNLMFVEDAARRIQVALDGRFANPRVHVRHLESLHPHDAVAWAAPLQMKHSR
EVAA

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 35647; Mature: 35647

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGHWGCLPNPNESMSAALPDVSLTEASPTFTPLEWVGMQGIDLPIRLVEPGYRRQLHA
CCCCCCCCCCCCCCCHHHCCCCCEECCCCCCCCCHHHCCCCCCCCCEEECCCCHHHHHCC
RADIHVDLPAPRVKGIHMSRLYALLDALDDGEGLSPIRIRQLLEAMVDSHRDCETGSARL
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEE
RLRFDLLVRRPALVTEGIAGWKSYPVRLDASLVGNVFALTARITAGYSSTCPCSAALTRQ
EEEEEHHHCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LVEQGFAKAFAHERRVDVARVSAWLRQHGTLATPHSQRSEASITVDIAVDLPNLGLLDLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHH
DHIERALGTPVQTAVKRADEQAFAALNGQNLMFVEDAARRIQVALDGRFANPRVHVRHLE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHEEEEEECCCCCCCEEHHHHHH
SLHPHDAVAWAAPLQMKHSREVAA
HCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRPGHWGCLPNPNESMSAALPDVSLTEASPTFTPLEWVGMQGIDLPIRLVEPGYRRQLHA
CCCCCCCCCCCCCCCHHHCCCCCEECCCCCCCCCHHHCCCCCCCCCEEECCCCHHHHHCC
RADIHVDLPAPRVKGIHMSRLYALLDALDDGEGLSPIRIRQLLEAMVDSHRDCETGSARL
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEE
RLRFDLLVRRPALVTEGIAGWKSYPVRLDASLVGNVFALTARITAGYSSTCPCSAALTRQ
EEEEEHHHCCCHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LVEQGFAKAFAHERRVDVARVSAWLRQHGTLATPHSQRSEASITVDIAVDLPNLGLLDLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHH
DHIERALGTPVQTAVKRADEQAFAALNGQNLMFVEDAARRIQVALDGRFANPRVHVRHLE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHHHEEEEEECCCCCCCEEHHHHHH
SLHPHDAVAWAAPLQMKHSREVAA
HCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA