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The map label for this gene is queD [H]

Identifier: 94310046

GI number: 94310046

Start: 1198548

End: 1199129

Strand: Direct

Name: queD [H]

Synonym: Rmet_1101

Alternate gene names: 94310046

Gene position: 1198548-1199129 (Clockwise)

Preceding gene: 94310045

Following gene: 94310047

Centisome position: 30.51

GC content: 58.76

Gene sequence:

>582_bases
GTGTCATGTGACGAAGCCATGCTGATTCGCAAGCTCTTCCGCTTCGAGAACGCCCATATCGTGCGCGGATGCAGCACGAG
GCGCTGCTCGCACTCCATCCACGGGCACTCGTACAAGATCGAATTACTGCTGGAGGCACACTCACTCGACCATGGACAGA
TGGTCTATGACTTCGGCCTGCTCAAAGGCGGCGCGTTTACGTTGATCGACGCCTTCGACCATGCGGTCACGCTATGGACC
GGCGACGACCCAGCGTATCTGGCGGCCATGCGCCAGCATTCAGAGCGTTGGGTGTTGATACCGGTGTCGCCAAGCGCCGA
ACAATTTTCAAGGTTGTTCTTCTTGCTGGTGGATGCGGTGCTAGCCACAACCGCCTTGCGCAATGGCGAGGGTGACGTGC
GATTGCACTCCGTCATCGTCCATGAAACGGAGACCGGCTATGCGCAGTGTTTCCGTGAGGATGCCGAGAATCCCCGCATG
GGACGCATCGATCTTGAATCCATCGTCTTCGCCCCAGCCATCACGGCGCAATGGAGCGACCCGGCGTTGTTCGAACGGTT
AAAACGCGCGCGTGCGGATTAG

Upstream 100 bases:

>100_bases
ACTGCGTGAGGAACTTGGCGCGGCCGGTGTCCTGGTTCACGACACGCCCAATGGGAGTACCTGGACCCTTGTCGATGGAA
CTCCAGCATAAGGGCGGCGG

Downstream 100 bases:

>100_bases
CACGCCAGGAATCCGCAACATGATCAGAAAGAATCCGAGCGGCGATCTGCCGCAGATTCATCCGAGCGCCTTCGTTGACC
CGACGGCCGTCCTGTGCGGC

Product: putative 6-pyruvoyl-tetrahydropterin (PTP)synthase

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSCDEAMLIRKLFRFENAHIVRGCSTRRCSHSIHGHSYKIELLLEAHSLDHGQMVYDFGLLKGGAFTLIDAFDHAVTLWT
GDDPAYLAAMRQHSERWVLIPVSPSAEQFSRLFFLLVDAVLATTALRNGEGDVRLHSVIVHETETGYAQCFREDAENPRM
GRIDLESIVFAPAITAQWSDPALFERLKRARAD

Sequences:

>Translated_193_residues
MSCDEAMLIRKLFRFENAHIVRGCSTRRCSHSIHGHSYKIELLLEAHSLDHGQMVYDFGLLKGGAFTLIDAFDHAVTLWT
GDDPAYLAAMRQHSERWVLIPVSPSAEQFSRLFFLLVDAVLATTALRNGEGDVRLHSVIVHETETGYAQCFREDAENPRM
GRIDLESIVFAPAITAQWSDPALFERLKRARAD
>Mature_192_residues
SCDEAMLIRKLFRFENAHIVRGCSTRRCSHSIHGHSYKIELLLEAHSLDHGQMVYDFGLLKGGAFTLIDAFDHAVTLWTG
DDPAYLAAMRQHSERWVLIPVSPSAEQFSRLFFLLVDAVLATTALRNGEGDVRLHSVIVHETETGYAQCFREDAENPRMG
RIDLESIVFAPAITAQWSDPALFERLKRARAD

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 21801; Mature: 21670

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCDEAMLIRKLFRFENAHIVRGCSTRRCSHSIHGHSYKIELLLEAHSLDHGQMVYDFGL
CCCHHHHHHHHHHHCCCCEEEECCCCCHHHCCCCCCEEEEEEEEEECCCCCCCEEEEHHH
LKGGAFTLIDAFDHAVTLWTGDDPAYLAAMRQHSERWVLIPVSPSAEQFSRLFFLLVDAV
HCCCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
LATTALRNGEGDVRLHSVIVHETETGYAQCFREDAENPRMGRIDLESIVFAPAITAQWSD
HHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCEEHHHHHCCCEEECCCCC
PALFERLKRARAD
HHHHHHHHHHCCC
>Mature Secondary Structure 
SCDEAMLIRKLFRFENAHIVRGCSTRRCSHSIHGHSYKIELLLEAHSLDHGQMVYDFGL
CCHHHHHHHHHHHCCCCEEEECCCCCHHHCCCCCCEEEEEEEEEECCCCCCCEEEEHHH
LKGGAFTLIDAFDHAVTLWTGDDPAYLAAMRQHSERWVLIPVSPSAEQFSRLFFLLVDAV
HCCCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
LATTALRNGEGDVRLHSVIVHETETGYAQCFREDAENPRMGRIDLESIVFAPAITAQWSD
HHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCEEHHHHHCCCEEECCCCC
PALFERLKRARAD
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]