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The map label for this gene is yngJ [H]

Identifier: 94309890

GI number: 94309890

Start: 1030554

End: 1031672

Strand: Direct

Name: yngJ [H]

Synonym: Rmet_0945

Alternate gene names: 94309890

Gene position: 1030554-1031672 (Clockwise)

Preceding gene: 94309889

Following gene: 94309891

Centisome position: 26.24

GC content: 66.13

Gene sequence:

>1119_bases
ATGAACTTCAATCTCAGCGACGAACAGAAGCAACTGGCCGACGCGATTCGCCGTTTTGTCGAGAAGAGCTACGACTTCGA
ATCGCGCAAGAAGAACATCAAGGGCGCGAATGGCTACGGCGAGCAAGCCTGGGGCGGACTGGTCGAACTCGGCCTGACCG
CGCTGCCGGTGCCCGAAGCGCAAGGTGGCTTCTCCGGTACGGCTGTCGACATGATGGTGGTGCAGCAGGAACTGGGCCGC
GGCCTGGTGGTGGAGCCGTACTTCGCGACGGTGGTGGCCGCGCAGGCGCTCAAGCTGGCCGGTGGCCAGGAAGCGCTGCT
CGAGCAGGTGGCTGGTGGCGAACTGAAGCTGGCCACGGCATTCAACGAGCAGCAGGCACGCCATGAACTGAACAACGTGA
CCGTGACGGCCAAGGGCGGCAAGCTCAACGGTCGCAAGGTCGTGGTGACCCACGGTGCCCAGGCCGACAAGCTCGTGGTG
TCGGCACGCACCAGTGGCGCCCAGTCGGACCGTGACGGCATCTCGCTGTTCCTGGTCGACACCAAGGGTGCTGGCGTCAG
CGTCAAGGACTACCGCACGATCGACAACCTCCACGCGGCCGACGTGACGTTCCAGGATGCACCGGCCACGCTGATCGGCA
CGGAAGGCAAGGGCTGGGATGTGCTCGAGGCCACCGCCGACTACGCCGCGGTGCTGCTGTGCGCCGAAGCCGTTGGTGTC
ATGGATACGCTCAACGCCGCCACGCTCGAGTACGCGAAGACCCGCCAGCAGTTCGGCGTGGCCATCGCGCGCTTCCAGGC
GCTGCAGCACCGCATGGTCGAAATGATGATCCATGCGGAGCAGTCGCGTTCGATCACGCTGCTGGCCGCGGCGCGCTTCG
ACGAGGCCAGCCCCGAGGAGCGCCGCCGCTACGTGTCCGCCGCCAAGGCGCGCGTCGGCGTGGCAGCCCGCTCGGTGGGC
CAGGAAGCCGTGCAGATTCACGGCGGCATGGGTGTGACCGACGAGCTGCCGGCCGCGCATATGTTCAAGCGCCTCACGCT
GATCAATACGACCTTCGGCGATGTGGACCACCATCTGGGCCGCTTCGCCAGCCAGCCTGGCTTCCAGGAAGCTGCCTGA

Upstream 100 bases:

>100_bases
TACTTCAACTATCGCAAGACCTCCATCTACGGCGGTTCGAACGAAATCCAAAAGAACATCATCAGCCAGATGATTCTGGG
GCTGTGAGGAGACACGCAAC

Downstream 100 bases:

>100_bases
GTATTGCGTAAGTGTTCAAACCGCGCCGGTGACCCCGAGCGCGGTTTTTTTCATTGGAGGACTTGATGTCCAAGATGTAT
TTCGAGGATTACGTCGTCGG

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNFNLSDEQKQLADAIRRFVEKSYDFESRKKNIKGANGYGEQAWGGLVELGLTALPVPEAQGGFSGTAVDMMVVQQELGR
GLVVEPYFATVVAAQALKLAGGQEALLEQVAGGELKLATAFNEQQARHELNNVTVTAKGGKLNGRKVVVTHGAQADKLVV
SARTSGAQSDRDGISLFLVDTKGAGVSVKDYRTIDNLHAADVTFQDAPATLIGTEGKGWDVLEATADYAAVLLCAEAVGV
MDTLNAATLEYAKTRQQFGVAIARFQALQHRMVEMMIHAEQSRSITLLAAARFDEASPEERRRYVSAAKARVGVAARSVG
QEAVQIHGGMGVTDELPAAHMFKRLTLINTTFGDVDHHLGRFASQPGFQEAA

Sequences:

>Translated_372_residues
MNFNLSDEQKQLADAIRRFVEKSYDFESRKKNIKGANGYGEQAWGGLVELGLTALPVPEAQGGFSGTAVDMMVVQQELGR
GLVVEPYFATVVAAQALKLAGGQEALLEQVAGGELKLATAFNEQQARHELNNVTVTAKGGKLNGRKVVVTHGAQADKLVV
SARTSGAQSDRDGISLFLVDTKGAGVSVKDYRTIDNLHAADVTFQDAPATLIGTEGKGWDVLEATADYAAVLLCAEAVGV
MDTLNAATLEYAKTRQQFGVAIARFQALQHRMVEMMIHAEQSRSITLLAAARFDEASPEERRRYVSAAKARVGVAARSVG
QEAVQIHGGMGVTDELPAAHMFKRLTLINTTFGDVDHHLGRFASQPGFQEAA
>Mature_372_residues
MNFNLSDEQKQLADAIRRFVEKSYDFESRKKNIKGANGYGEQAWGGLVELGLTALPVPEAQGGFSGTAVDMMVVQQELGR
GLVVEPYFATVVAAQALKLAGGQEALLEQVAGGELKLATAFNEQQARHELNNVTVTAKGGKLNGRKVVVTHGAQADKLVV
SARTSGAQSDRDGISLFLVDTKGAGVSVKDYRTIDNLHAADVTFQDAPATLIGTEGKGWDVLEATADYAAVLLCAEAVGV
MDTLNAATLEYAKTRQQFGVAIARFQALQHRMVEMMIHAEQSRSITLLAAARFDEASPEERRRYVSAAKARVGVAARSVG
QEAVQIHGGMGVTDELPAAHMFKRLTLINTTFGDVDHHLGRFASQPGFQEAA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=317, Percent_Identity=26.813880126183, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI226958412, Length=366, Percent_Identity=26.2295081967213, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4501857, Length=362, Percent_Identity=25.414364640884, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI226958414, Length=328, Percent_Identity=26.5243902439024, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI21361497, Length=391, Percent_Identity=26.3427109974425, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI76496475, Length=389, Percent_Identity=24.6786632390745, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4557235, Length=389, Percent_Identity=24.6786632390745, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4557231, Length=395, Percent_Identity=25.0632911392405, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI187960098, Length=395, Percent_Identity=25.0632911392405, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786223, Length=355, Percent_Identity=27.6056338028169, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081958, Length=356, Percent_Identity=23.314606741573, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=365, Percent_Identity=27.3972602739726, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=26.1707988980716, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=26.4864864864865, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=368, Percent_Identity=25.8152173913043, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=24.8648648648649, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=360, Percent_Identity=22.5, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=26.1838440111421, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355753, Length=364, Percent_Identity=27.4725274725275, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=27.8378378378378, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356377, Length=362, Percent_Identity=25.414364640884, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646207, Length=326, Percent_Identity=25.1533742331288, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363737, Length=357, Percent_Identity=24.0896358543417, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 39844; Mature: 39844

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNLSDEQKQLADAIRRFVEKSYDFESRKKNIKGANGYGEQAWGGLVELGLTALPVPEA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
QGGFSGTAVDMMVVQQELGRGLVVEPYFATVVAAQALKLAGGQEALLEQVAGGELKLATA
CCCCCCHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEH
FNEQQARHELNNVTVTAKGGKLNGRKVVVTHGAQADKLVVSARTSGAQSDRDGISLFLVD
HHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEE
TKGAGVSVKDYRTIDNLHAADVTFQDAPATLIGTEGKGWDVLEATADYAAVLLCAEAVGV
CCCCCCCHHHHHHHCCCCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MDTLNAATLEYAKTRQQFGVAIARFQALQHRMVEMMIHAEQSRSITLLAAARFDEASPEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
RRRYVSAAKARVGVAARSVGQEAVQIHGGMGVTDELPAAHMFKRLTLINTTFGDVDHHLG
HHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
RFASQPGFQEAA
HHHCCCCCCCCC
>Mature Secondary Structure
MNFNLSDEQKQLADAIRRFVEKSYDFESRKKNIKGANGYGEQAWGGLVELGLTALPVPEA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
QGGFSGTAVDMMVVQQELGRGLVVEPYFATVVAAQALKLAGGQEALLEQVAGGELKLATA
CCCCCCHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEH
FNEQQARHELNNVTVTAKGGKLNGRKVVVTHGAQADKLVVSARTSGAQSDRDGISLFLVD
HHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEE
TKGAGVSVKDYRTIDNLHAADVTFQDAPATLIGTEGKGWDVLEATADYAAVLLCAEAVGV
CCCCCCCHHHHHHHCCCCCCCEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
MDTLNAATLEYAKTRQQFGVAIARFQALQHRMVEMMIHAEQSRSITLLAAARFDEASPEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
RRRYVSAAKARVGVAARSVGQEAVQIHGGMGVTDELPAAHMFKRLTLINTTFGDVDHHLG
HHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
RFASQPGFQEAA
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]