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The map label for this gene is acdA [H]

Identifier: 94309889

GI number: 94309889

Start: 1029338

End: 1030540

Strand: Direct

Name: acdA [H]

Synonym: Rmet_0944

Alternate gene names: 94309889

Gene position: 1029338-1030540 (Clockwise)

Preceding gene: 94309888

Following gene: 94309890

Centisome position: 26.2

GC content: 62.43

Gene sequence:

>1203_bases
ATGGATCTCAATTACTCGGCGGCCGACATCGCCTTCCGTCAGGAAGTGCGTAGCTGGCTCGAAGCCAACCTGCCGGCGGA
AATCCGCGAAAAGGTACTCAACCACCGCCGCCCCAACCGCGACGATCTGGTGCGCTGGCACAAGATCCTGGCTGGCAAGG
GCTGGTCCGCGCCGCACTGGCCGGTCGAGTTCGGTGGCACGGGCTGGAACGCCACGCAACGCCACATCTGGGACGAGGAA
AATGCCCGCGTCGGCGCGCCTGGCGTGCTGCCGTTCGGCGTGGCGATGGTCGCGCCCGTGATCATGAAGTACGGCAATGC
AGAGCAGAAGTCGTACTACCTGCCGCGTATCCTCGACTGCACCGACTGGTGGTGCCAGGGCTATTCGGAGCCGGGTTCGG
GTTCGGATCTGGCTTCGCTGAAGACCCGTGCCGAGCTGACGTCGGATGGCAAGCACTACATCGTCAACGGCCAGAAGACC
TGGACCACGCTCGGCCAGCACGCCGACATGATCTTCTGCCTGGTGCGCACCGACCCCGAGGCCAAGAAGCAAGAGGGCAT
TTCGTTCCTGCTGATCGACATGAAGACGCCGGGCATTACCGTGCGCCCGATCATCATGCTCGACGAAGAGCATGAAGTGA
ACGAAGTCTTCTTCGACAACGTCAAGGTGCCGGTCGAAAACCGCGTCGGCGAGGAAAACCGTGGCTGGACCTATGCCAAG
TACCTGCTTGGCCATGAGCGTACCGGCATTGCGCGCGTGGGTAACTCCAAGCGCGAACTGGGCTTCCTGAAGCGCGTTGC
CCGCCAGCAGCAGAAGAACGGCAAGCCGCTGCTCGAGGATCCGGTGTTTGGCGCCAAGGTTGCCGCGCTGGAAATCGAAC
TGATGGCGCTGGAGATCACCGTGCTGCGCGTGGTGTCGAGCGAAGCCGCTGGCAAGGGCCCCGGCCCCGAGGCATCGATG
CTCAAGATCAAGGGCACCGAGATCCAGCAGATGCTGACCGAACTGATGGTCGAAGCGGTCGGCCCGTACGCCCAGCCGTT
CGATCCGGCGTACCTGGAGTGCGAACACGAGCACGCCGTGACCGGCTATGACGACGCCGCCCCGCTGGCCGCGTACTACT
TCAACTATCGCAAGACCTCCATCTACGGCGGTTCGAACGAAATCCAAAAGAACATCATCAGCCAGATGATTCTGGGGCTG
TGA

Upstream 100 bases:

>100_bases
GCCCACTGAACAAGCATCCTGTGCCCGGTTTACCTCGCGCAGTGATGCGCGAGGTAAAACAAACGGCCGGCGCCCGCCGG
CACCACCAATGGAGACGGGC

Downstream 100 bases:

>100_bases
GGAGACACGCAACATGAACTTCAATCTCAGCGACGAACAGAAGCAACTGGCCGACGCGATTCGCCGTTTTGTCGAGAAGA
GCTACGACTTCGAATCGCGC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MDLNYSAADIAFRQEVRSWLEANLPAEIREKVLNHRRPNRDDLVRWHKILAGKGWSAPHWPVEFGGTGWNATQRHIWDEE
NARVGAPGVLPFGVAMVAPVIMKYGNAEQKSYYLPRILDCTDWWCQGYSEPGSGSDLASLKTRAELTSDGKHYIVNGQKT
WTTLGQHADMIFCLVRTDPEAKKQEGISFLLIDMKTPGITVRPIIMLDEEHEVNEVFFDNVKVPVENRVGEENRGWTYAK
YLLGHERTGIARVGNSKRELGFLKRVARQQQKNGKPLLEDPVFGAKVAALEIELMALEITVLRVVSSEAAGKGPGPEASM
LKIKGTEIQQMLTELMVEAVGPYAQPFDPAYLECEHEHAVTGYDDAAPLAAYYFNYRKTSIYGGSNEIQKNIISQMILGL

Sequences:

>Translated_400_residues
MDLNYSAADIAFRQEVRSWLEANLPAEIREKVLNHRRPNRDDLVRWHKILAGKGWSAPHWPVEFGGTGWNATQRHIWDEE
NARVGAPGVLPFGVAMVAPVIMKYGNAEQKSYYLPRILDCTDWWCQGYSEPGSGSDLASLKTRAELTSDGKHYIVNGQKT
WTTLGQHADMIFCLVRTDPEAKKQEGISFLLIDMKTPGITVRPIIMLDEEHEVNEVFFDNVKVPVENRVGEENRGWTYAK
YLLGHERTGIARVGNSKRELGFLKRVARQQQKNGKPLLEDPVFGAKVAALEIELMALEITVLRVVSSEAAGKGPGPEASM
LKIKGTEIQQMLTELMVEAVGPYAQPFDPAYLECEHEHAVTGYDDAAPLAAYYFNYRKTSIYGGSNEIQKNIISQMILGL
>Mature_400_residues
MDLNYSAADIAFRQEVRSWLEANLPAEIREKVLNHRRPNRDDLVRWHKILAGKGWSAPHWPVEFGGTGWNATQRHIWDEE
NARVGAPGVLPFGVAMVAPVIMKYGNAEQKSYYLPRILDCTDWWCQGYSEPGSGSDLASLKTRAELTSDGKHYIVNGQKT
WTTLGQHADMIFCLVRTDPEAKKQEGISFLLIDMKTPGITVRPIIMLDEEHEVNEVFFDNVKVPVENRVGEENRGWTYAK
YLLGHERTGIARVGNSKRELGFLKRVARQQQKNGKPLLEDPVFGAKVAALEIELMALEITVLRVVSSEAAGKGPGPEASM
LKIKGTEIQQMLTELMVEAVGPYAQPFDPAYLECEHEHAVTGYDDAAPLAAYYFNYRKTSIYGGSNEIQKNIISQMILGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=342, Percent_Identity=28.9473684210526, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI4501857, Length=329, Percent_Identity=27.355623100304, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4557233, Length=362, Percent_Identity=26.5193370165746, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI187960098, Length=350, Percent_Identity=26.5714285714286, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4557231, Length=350, Percent_Identity=26.5714285714286, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI211971008, Length=309, Percent_Identity=25.5663430420712, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI48976061, Length=309, Percent_Identity=25.5663430420712, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI21361497, Length=293, Percent_Identity=30.0341296928328, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI226958412, Length=231, Percent_Identity=29.004329004329, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958414, Length=182, Percent_Identity=31.3186813186813, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7656849, Length=316, Percent_Identity=26.2658227848101, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI76496475, Length=157, Percent_Identity=35.031847133758, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4557235, Length=157, Percent_Identity=35.031847133758, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI7669494, Length=236, Percent_Identity=27.1186440677966, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4503943, Length=236, Percent_Identity=27.1186440677966, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87081958, Length=409, Percent_Identity=24.9388753056235, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786223, Length=358, Percent_Identity=23.1843575418994, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=391, Percent_Identity=26.0869565217391, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=201, Percent_Identity=34.8258706467662, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=26.3736263736264, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71985192, Length=201, Percent_Identity=34.8258706467662, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=364, Percent_Identity=27.1978021978022, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=245, Percent_Identity=30.6122448979592, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=419, Percent_Identity=25.0596658711217, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=205, Percent_Identity=33.1707317073171, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=313, Percent_Identity=26.1980830670927, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=354, Percent_Identity=25.1412429378531, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=269, Percent_Identity=25.6505576208178, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=354, Percent_Identity=24.2937853107345, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=352, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534353, Length=273, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24666513, Length=350, Percent_Identity=28.2857142857143, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281363737, Length=282, Percent_Identity=30.1418439716312, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356377, Length=351, Percent_Identity=25.0712250712251, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24660351, Length=358, Percent_Identity=26.8156424581006, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355753, Length=282, Percent_Identity=29.0780141843972, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24646207, Length=346, Percent_Identity=25.1445086705202, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920834, Length=347, Percent_Identity=24.207492795389, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44875; Mature: 44875

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNYSAADIAFRQEVRSWLEANLPAEIREKVLNHRRPNRDDLVRWHKILAGKGWSAPHW
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
PVEFGGTGWNATQRHIWDEENARVGAPGVLPFGVAMVAPVIMKYGNAEQKSYYLPRILDC
CEEECCCCCCCHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCC
TDWWCQGYSEPGSGSDLASLKTRAELTSDGKHYIVNGQKTWTTLGQHADMIFCLVRTDPE
CHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEEEEEEECCCC
AKKQEGISFLLIDMKTPGITVRPIIMLDEEHEVNEVFFDNVKVPVENRVGEENRGWTYAK
HHHHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHCCCCCCHHHCCCCCCCCEEHHH
YLLGHERTGIARVGNSKRELGFLKRVARQQQKNGKPLLEDPVFGAKVAALEIELMALEIT
HHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEHHHH
VLRVVSSEAAGKGPGPEASMLKIKGTEIQQMLTELMVEAVGPYAQPFDPAYLECEHEHAV
HHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCC
TGYDDAAPLAAYYFNYRKTSIYGGSNEIQKNIISQMILGL
CCCCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLNYSAADIAFRQEVRSWLEANLPAEIREKVLNHRRPNRDDLVRWHKILAGKGWSAPHW
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
PVEFGGTGWNATQRHIWDEENARVGAPGVLPFGVAMVAPVIMKYGNAEQKSYYLPRILDC
CEEECCCCCCCHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCC
TDWWCQGYSEPGSGSDLASLKTRAELTSDGKHYIVNGQKTWTTLGQHADMIFCLVRTDPE
CHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEEEEEEECCCC
AKKQEGISFLLIDMKTPGITVRPIIMLDEEHEVNEVFFDNVKVPVENRVGEENRGWTYAK
HHHHCCCEEEEEEECCCCEEEEEEEEECCCCCHHHHHHCCCCCCHHHCCCCCCCCEEHHH
YLLGHERTGIARVGNSKRELGFLKRVARQQQKNGKPLLEDPVFGAKVAALEIELMALEIT
HHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEHHHH
VLRVVSSEAAGKGPGPEASMLKIKGTEIQQMLTELMVEAVGPYAQPFDPAYLECEHEHAV
HHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCC
TGYDDAAPLAAYYFNYRKTSIYGGSNEIQKNIISQMILGL
CCCCCCCHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]