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The map label for this gene is lldD [H]

Identifier: 94309784

GI number: 94309784

Start: 918190

End: 919275

Strand: Direct

Name: lldD [H]

Synonym: Rmet_0839

Alternate gene names: 94309784

Gene position: 918190-919275 (Clockwise)

Preceding gene: 94309783

Following gene: 94309786

Centisome position: 23.37

GC content: 65.47

Gene sequence:

>1086_bases
ATGCAGATCCCCACCGACACTGTTTCGCTGCGTGACTACGAATATCGCTTTCACGAAAGGGTGGACCCGGCGATTCGCGC
CTACATCGCGGGCGCGGCGGCCGATGCAGTAACGCAGCGCGAGAACGGTGCCGCATTCGAGCGCATCAGGCTGATGCCTC
GCGCGCTTGTCGACATGTCGCAGGCATCGGCCCGGTCCGAACTGTTCGGCGAGACGCTCGACTATCCGATCCTGATTGCC
CCAACCGCGTATCACAAGCTCGTCCATCCCGACGGTGAGCTGGCGACGGTTCAGGGGGCGTCCCTCACCCGCACCTGGAT
GACTGTCAGCACCCAGGCCAGCGTCACGCTGGAAGAGGTCGCGCGCGCATCCACCGCGCCACTCTGGTTTCAGCTCTACA
TGCAGCCACGTCGCGAGGATTCGCTGGCGCTGGTCCGCAGGGCGGAGCAGGCGGGCTACAAGGCGTTGGTGGTGACGATC
GACGCTGCTGTCAGCGGCATCCGCAATGTCGAGCAGCGCGCGGGGTTTCGATTGCCCGATGGCGTCAGCGCGGTCAATCT
TGCTGGGTTTGCCGCGAACGAGCCGATTCGCGCAAGCGTCGGGAGTCCGATCTTTCGCGGTATGTTGGCCCATGCACCTA
CCTGGTCTGACATCGAGTGGCTATGCGGACAGACCACGTTGCCGGTACTCGTCAAGGGCTTGCTCAATCCGGCCGACGTG
CCTGCCGCGCTGAATGCGGGGGTGTCGGGCATCATCGTGTCGAATCACGGTGGCCGCGTGCTCGACACGCTTCCCGCCAC
GATCGACGTGCTGCCCGCTGTTGCCGCCGCCGTGGCTGGTGCCGTGCCGATCCTGCTCGACGGCGGCGTGCGGCGCGGTA
CGGATATCGTCAAGGCGATCGCGCTGGGTGCCTCCGCGGTACTGCTTGGCCAGCCAGTGTTGCACGCGCTGGCGGTCGGC
GGGATGCCGGGCGTGGTCCATATGCTGACGCTGCTGCAAACCGAACTGGAAGCCGCGATGGCATTGCTCGGCAGGCCGAC
ACTGCGCGATATTGATGCGTCGACGTTGATGGGCCGGACGGCGTAG

Upstream 100 bases:

>100_bases
TGGAAGTCCGCAGGCAACTCGGCGACGACAAAGACGCCGTGCTCGCGCTGGTCAACCACTATCACAACCTGCTCAGGCGC
TGGGCAGAGCTTTGACTCCC

Downstream 100 bases:

>100_bases
CGCTATCCAGCCGGGTTCATCGTCGATAGCTCCCGCACCATCAACGCGCCGAGTTCGTCTCGGCGGCTTGCGTTCATGCG
GCTGCTGATCGCGCCGAAGC

Product: (S)-2-hydroxy-acid oxidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MQIPTDTVSLRDYEYRFHERVDPAIRAYIAGAAADAVTQRENGAAFERIRLMPRALVDMSQASARSELFGETLDYPILIA
PTAYHKLVHPDGELATVQGASLTRTWMTVSTQASVTLEEVARASTAPLWFQLYMQPRREDSLALVRRAEQAGYKALVVTI
DAAVSGIRNVEQRAGFRLPDGVSAVNLAGFAANEPIRASVGSPIFRGMLAHAPTWSDIEWLCGQTTLPVLVKGLLNPADV
PAALNAGVSGIIVSNHGGRVLDTLPATIDVLPAVAAAVAGAVPILLDGGVRRGTDIVKAIALGASAVLLGQPVLHALAVG
GMPGVVHMLTLLQTELEAAMALLGRPTLRDIDASTLMGRTA

Sequences:

>Translated_361_residues
MQIPTDTVSLRDYEYRFHERVDPAIRAYIAGAAADAVTQRENGAAFERIRLMPRALVDMSQASARSELFGETLDYPILIA
PTAYHKLVHPDGELATVQGASLTRTWMTVSTQASVTLEEVARASTAPLWFQLYMQPRREDSLALVRRAEQAGYKALVVTI
DAAVSGIRNVEQRAGFRLPDGVSAVNLAGFAANEPIRASVGSPIFRGMLAHAPTWSDIEWLCGQTTLPVLVKGLLNPADV
PAALNAGVSGIIVSNHGGRVLDTLPATIDVLPAVAAAVAGAVPILLDGGVRRGTDIVKAIALGASAVLLGQPVLHALAVG
GMPGVVHMLTLLQTELEAAMALLGRPTLRDIDASTLMGRTA
>Mature_361_residues
MQIPTDTVSLRDYEYRFHERVDPAIRAYIAGAAADAVTQRENGAAFERIRLMPRALVDMSQASARSELFGETLDYPILIA
PTAYHKLVHPDGELATVQGASLTRTWMTVSTQASVTLEEVARASTAPLWFQLYMQPRREDSLALVRRAEQAGYKALVVTI
DAAVSGIRNVEQRAGFRLPDGVSAVNLAGFAANEPIRASVGSPIFRGMLAHAPTWSDIEWLCGQTTLPVLVKGLLNPADV
PAALNAGVSGIIVSNHGGRVLDTLPATIDVLPAVAAAVAGAVPILLDGGVRRGTDIVKAIALGASAVLLGQPVLHALAVG
GMPGVVHMLTLLQTELEAAMALLGRPTLRDIDASTLMGRTA

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=347, Percent_Identity=40.0576368876081, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI7705393, Length=347, Percent_Identity=40.0576368876081, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI11068137, Length=353, Percent_Identity=39.0934844192635, Blast_Score=242, Evalue=5e-64,
Organism=Escherichia coli, GI1790033, Length=369, Percent_Identity=33.6043360433604, Blast_Score=186, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI193208036, Length=356, Percent_Identity=36.5168539325843, Blast_Score=220, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI32566217, Length=273, Percent_Identity=33.3333333333333, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323587, Length=377, Percent_Identity=34.2175066312997, Blast_Score=199, Evalue=8e-52,
Organism=Drosophila melanogaster, GI281363140, Length=355, Percent_Identity=38.5915492957746, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI78707190, Length=355, Percent_Identity=38.5915492957746, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI78707188, Length=355, Percent_Identity=38.5915492957746, Blast_Score=235, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 38187; Mature: 38187

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIPTDTVSLRDYEYRFHERVDPAIRAYIAGAAADAVTQRENGAAFERIRLMPRALVDMS
CCCCCCCEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QASARSELFGETLDYPILIAPTAYHKLVHPDGELATVQGASLTRTWMTVSTQASVTLEEV
HHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCCEEEECCCCEEEEEEEEECCCCEEHHHH
ARASTAPLWFQLYMQPRREDSLALVRRAEQAGYKALVVTIDAAVSGIRNVEQRAGFRLPD
HCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCC
GVSAVNLAGFAANEPIRASVGSPIFRGMLAHAPTWSDIEWLCGQTTLPVLVKGLLNPADV
CCCCEEECCCCCCCCCHHCCCCHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCCC
PAALNAGVSGIIVSNHGGRVLDTLPATIDVLPAVAAAVAGAVPILLDGGVRRGTDIVKAI
CHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
ALGASAVLLGQPVLHALAVGGMPGVVHMLTLLQTELEAAMALLGRPTLRDIDASTLMGRT
HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCC
A
C
>Mature Secondary Structure
MQIPTDTVSLRDYEYRFHERVDPAIRAYIAGAAADAVTQRENGAAFERIRLMPRALVDMS
CCCCCCCEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QASARSELFGETLDYPILIAPTAYHKLVHPDGELATVQGASLTRTWMTVSTQASVTLEEV
HHHHHHHHHHHHCCCCEEECCHHHHHHCCCCCCEEEECCCCEEEEEEEEECCCCEEHHHH
ARASTAPLWFQLYMQPRREDSLALVRRAEQAGYKALVVTIDAAVSGIRNVEQRAGFRLPD
HCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCC
GVSAVNLAGFAANEPIRASVGSPIFRGMLAHAPTWSDIEWLCGQTTLPVLVKGLLNPADV
CCCCEEECCCCCCCCCHHCCCCHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCCC
PAALNAGVSGIIVSNHGGRVLDTLPATIDVLPAVAAAVAGAVPILLDGGVRRGTDIVKAI
CHHHHCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
ALGASAVLLGQPVLHALAVGGMPGVVHMLTLLQTELEAAMALLGRPTLRDIDASTLMGRT
HHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA