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The map label for this gene is aldH [H]

Identifier: 94309777

GI number: 94309777

Start: 908723

End: 910300

Strand: Reverse

Name: aldH [H]

Synonym: Rmet_0832

Alternate gene names: 94309777

Gene position: 910300-908723 (Counterclockwise)

Preceding gene: 94309778

Following gene: 94309775

Centisome position: 23.17

GC content: 68.88

Gene sequence:

>1578_bases
ATGACGATTACCGGCGAAATGCTGATCGGCGCGAGCGCCGTGCGCGGCACAGAAGAGACGTTTTACGGAATCAACCCGGC
CACCGGCGAGCAACTCGAACCGGCATTCCACAGCGGCAATGCCAACGACGTCGAGCGCGCCTGCGTGCTGGCGGAGGCGG
CGTTCGATGCCTATCGCGCCACCACGCCCGAACAACGTGCCCAGTTCCTGGAGTCGATTGCCGACGCCATCGAAGCCATT
GGCGACGAACTGATCCAGCGCGCGCACGCCGAAACGGCGCTGCCGCTCGCCCGCCTCCAGGGCGAGCGCGGCCGAACCAC
CGGCCAATTGCGCCTGTTCGCCCGGGTGCTGCGCGACGGCCGCTGGCAGGATGCCACGCTCGACAGCGCCCTGCCCGAGC
GCACCCCGCCGCGCCCCGACCTGCGGATGCAGAAGATCGCGGTCGGTCCCGTGGCCGTGTTCGGCGCCAGCAACTTCCCG
CTGGCGTTCTCGGTGGCCGGCGGCGACACGGCGTCCGCGCTGGCCGCCGGTTGTCCGGTGGTTGCCAAGGCTCACCCCGC
TCACCCCGGCACTTCCGAACTGGTTGGCCGCGCCATCCAGAAGGCCGTGGCCGACAGCGGTCTGCCTGAAGGCGTGTTCT
CGCTCATAATGGGTGTCGGTAATGCGATCGGCACGGCGCTGGTTGCCCACCCTGCCATCCAGGCGGTCGGGTTCACCGGA
TCACGCACCGGTGGGCTGGCCCTGATGAACGTGGCCAACACGCGCCCGCAGCCGATCCCGGTCTATGCCGAGATGAGCAG
CATCAACCCCGTATACCTGCTGCCCGAAGCCTTGGCCGCGCGCGGCGAACAGATTGCCCGCGACCTGATCGACTCGCTGG
TGCTCGGCGTCGGCCAGTTCTGCACGAACCCCGGCCTGCTGCTGGCCATCGAAGGTCCGGCCCTCGAGGCATTCCGCGCG
ACGGCCCTGGCCGCGCTGACGGGCAAACCCGCCGCCACCATGCTGACGCCGGGCATCCACCAGGCGTTCGAACGTGGCGT
CACGCAACTCTCCGATATCGCCGGGCTCTCGCGTGCGGCCTGCGGACTGGATGCGACGGGCCCGAACCAGGCGCGCCCGG
TATTCTTCGAGACCTCGGCGGAGCAGTTCATTGCCGACCACCGCATGCACGTCGAAGTCTTCGGCCCGTCCACGGTACTG
GTCACCTGCAAGGATGCCGAGACGCTGCTAGCCGTGACGCGCATCCTGGAAGGCCAGCTCACCGCCACGGTGCAGGCAGA
TGCCGGCGACCACGCACTGGCGGCCCGCTTGCTCCCCGCGCTGGAGCGCAAGGTCGGTCGTGTGCTGTTCAATGGCTTCC
CGACCGGCGTGGAAGTGTCGTTCGCGATGGTCCACGGTGGCCCGTTCCCGGCCACGTCGGACACGCGCACAACCTCGGTA
GGCGCTAGCGCGATCGACCGGTTCCTGCGTCCGGTGTGCTACCAGAACGTGCCGGCGGACCTGCTGCCGCAAGCGGTGCG
GGACAGCAACCCGCTAAACCTGTGGCGACTGAAGGACGGCGAACTCGGCCGCGCCTGA

Upstream 100 bases:

>100_bases
CCATGTCATATGATGTCTTACGACAAAACCACTTCCAATCTGATGTGACGGCCACGCTGGCCGCCATGCCAATCCCTCCT
CACCCGCAGGACCCAAGATC

Downstream 100 bases:

>100_bases
TCTGTCGACTTCGCAATAAAAAACGGCTGCTCACGCAGCCGTTTTTTATTTCTCGAGAAAGGCCTTCCGTTACGGGAGGC
CTTTCTCATTGATGCCGACG

Product: NADP-dependent fatty aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MTITGEMLIGASAVRGTEETFYGINPATGEQLEPAFHSGNANDVERACVLAEAAFDAYRATTPEQRAQFLESIADAIEAI
GDELIQRAHAETALPLARLQGERGRTTGQLRLFARVLRDGRWQDATLDSALPERTPPRPDLRMQKIAVGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVVAKAHPAHPGTSELVGRAIQKAVADSGLPEGVFSLIMGVGNAIGTALVAHPAIQAVGFTG
SRTGGLALMNVANTRPQPIPVYAEMSSINPVYLLPEALAARGEQIARDLIDSLVLGVGQFCTNPGLLLAIEGPALEAFRA
TALAALTGKPAATMLTPGIHQAFERGVTQLSDIAGLSRAACGLDATGPNQARPVFFETSAEQFIADHRMHVEVFGPSTVL
VTCKDAETLLAVTRILEGQLTATVQADAGDHALAARLLPALERKVGRVLFNGFPTGVEVSFAMVHGGPFPATSDTRTTSV
GASAIDRFLRPVCYQNVPADLLPQAVRDSNPLNLWRLKDGELGRA

Sequences:

>Translated_525_residues
MTITGEMLIGASAVRGTEETFYGINPATGEQLEPAFHSGNANDVERACVLAEAAFDAYRATTPEQRAQFLESIADAIEAI
GDELIQRAHAETALPLARLQGERGRTTGQLRLFARVLRDGRWQDATLDSALPERTPPRPDLRMQKIAVGPVAVFGASNFP
LAFSVAGGDTASALAAGCPVVAKAHPAHPGTSELVGRAIQKAVADSGLPEGVFSLIMGVGNAIGTALVAHPAIQAVGFTG
SRTGGLALMNVANTRPQPIPVYAEMSSINPVYLLPEALAARGEQIARDLIDSLVLGVGQFCTNPGLLLAIEGPALEAFRA
TALAALTGKPAATMLTPGIHQAFERGVTQLSDIAGLSRAACGLDATGPNQARPVFFETSAEQFIADHRMHVEVFGPSTVL
VTCKDAETLLAVTRILEGQLTATVQADAGDHALAARLLPALERKVGRVLFNGFPTGVEVSFAMVHGGPFPATSDTRTTSV
GASAIDRFLRPVCYQNVPADLLPQAVRDSNPLNLWRLKDGELGRA
>Mature_524_residues
TITGEMLIGASAVRGTEETFYGINPATGEQLEPAFHSGNANDVERACVLAEAAFDAYRATTPEQRAQFLESIADAIEAIG
DELIQRAHAETALPLARLQGERGRTTGQLRLFARVLRDGRWQDATLDSALPERTPPRPDLRMQKIAVGPVAVFGASNFPL
AFSVAGGDTASALAAGCPVVAKAHPAHPGTSELVGRAIQKAVADSGLPEGVFSLIMGVGNAIGTALVAHPAIQAVGFTGS
RTGGLALMNVANTRPQPIPVYAEMSSINPVYLLPEALAARGEQIARDLIDSLVLGVGQFCTNPGLLLAIEGPALEAFRAT
ALAALTGKPAATMLTPGIHQAFERGVTQLSDIAGLSRAACGLDATGPNQARPVFFETSAEQFIADHRMHVEVFGPSTVLV
TCKDAETLLAVTRILEGQLTATVQADAGDHALAARLLPALERKVGRVLFNGFPTGVEVSFAMVHGGPFPATSDTRTTSVG
ASAIDRFLRPVCYQNVPADLLPQAVRDSNPLNLWRLKDGELGRA

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=457, Percent_Identity=25.601750547046, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI12007648, Length=436, Percent_Identity=24.3119266055046, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI25952152, Length=256, Percent_Identity=26.171875, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI21614513, Length=400, Percent_Identity=24.25, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081896, Length=429, Percent_Identity=26.5734265734266, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786504, Length=455, Percent_Identity=25.9340659340659, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788042, Length=340, Percent_Identity=28.8235294117647, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787558, Length=281, Percent_Identity=28.8256227758007, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081926, Length=473, Percent_Identity=25.369978858351, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787250, Length=283, Percent_Identity=27.9151943462898, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789015, Length=225, Percent_Identity=28.4444444444444, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787684, Length=279, Percent_Identity=26.5232974910394, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI133930964, Length=277, Percent_Identity=27.4368231046931, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25143876, Length=312, Percent_Identity=23.7179487179487, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25143874, Length=312, Percent_Identity=23.7179487179487, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=315, Percent_Identity=28.8888888888889, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319478, Length=255, Percent_Identity=28.2352941176471, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=255, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324950, Length=433, Percent_Identity=24.0184757505774, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585660, Length=256, Percent_Identity=28.90625, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281362580, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62472918, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62472926, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62472936, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356737, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 55035; Mature: 54904

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITGEMLIGASAVRGTEETFYGINPATGEQLEPAFHSGNANDVERACVLAEAAFDAYRA
CEEECCHHHCHHHHCCCCHHEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHC
TTPEQRAQFLESIADAIEAIGDELIQRAHAETALPLARLQGERGRTTGQLRLFARVLRDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
RWQDATLDSALPERTPPRPDLRMQKIAVGPVAVFGASNFPLAFSVAGGDTASALAAGCPV
CCCCCCHHHCCCCCCCCCCCCEEHHEEECCEEEECCCCCCEEEEECCCCHHHHHHHCCCE
VAKAHPAHPGTSELVGRAIQKAVADSGLPEGVFSLIMGVGNAIGTALVAHPAIQAVGFTG
EECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SRTGGLALMNVANTRPQPIPVYAEMSSINPVYLLPEALAARGEQIARDLIDSLVLGVGQF
CCCCCEEEEEECCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
CTNPGLLLAIEGPALEAFRATALAALTGKPAATMLTPGIHQAFERGVTQLSDIAGLSRAA
HCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
CGLDATGPNQARPVFFETSAEQFIADHRMHVEVFGPSTVLVTCKDAETLLAVTRILEGQL
CCCCCCCCCCCCCEEEECCHHHHHHCCCEEEEEECCCEEEEEECCHHHHHHHHHHHCCCE
TATVQADAGDHALAARLLPALERKVGRVLFNGFPTGVEVSFAMVHGGPFPATSDTRTTSV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
GASAIDRFLRPVCYQNVPADLLPQAVRDSNPLNLWRLKDGELGRA
CHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TITGEMLIGASAVRGTEETFYGINPATGEQLEPAFHSGNANDVERACVLAEAAFDAYRA
EEECCHHHCHHHHCCCCHHEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHC
TTPEQRAQFLESIADAIEAIGDELIQRAHAETALPLARLQGERGRTTGQLRLFARVLRDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
RWQDATLDSALPERTPPRPDLRMQKIAVGPVAVFGASNFPLAFSVAGGDTASALAAGCPV
CCCCCCHHHCCCCCCCCCCCCEEHHEEECCEEEECCCCCCEEEEECCCCHHHHHHHCCCE
VAKAHPAHPGTSELVGRAIQKAVADSGLPEGVFSLIMGVGNAIGTALVAHPAIQAVGFTG
EECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SRTGGLALMNVANTRPQPIPVYAEMSSINPVYLLPEALAARGEQIARDLIDSLVLGVGQF
CCCCCEEEEEECCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
CTNPGLLLAIEGPALEAFRATALAALTGKPAATMLTPGIHQAFERGVTQLSDIAGLSRAA
HCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
CGLDATGPNQARPVFFETSAEQFIADHRMHVEVFGPSTVLVTCKDAETLLAVTRILEGQL
CCCCCCCCCCCCCEEEECCHHHHHHCCCEEEEEECCCEEEEEECCHHHHHHHHHHHCCCE
TATVQADAGDHALAARLLPALERKVGRVLFNGFPTGVEVSFAMVHGGPFPATSDTRTTSV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
GASAIDRFLRPVCYQNVPADLLPQAVRDSNPLNLWRLKDGELGRA
CHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]