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The map label for this gene is gltS2 [H]

Identifier: 94309534

GI number: 94309534

Start: 632195

End: 633967

Strand: Reverse

Name: gltS2 [H]

Synonym: Rmet_0589

Alternate gene names: 94309534

Gene position: 633967-632195 (Counterclockwise)

Preceding gene: 94309535

Following gene: 94309533

Centisome position: 16.14

GC content: 68.92

Gene sequence:

>1773_bases
ATGCCCTCGCCATGGCGTCGCGTCGCGCCGTTCGTCGCCCTGCTCGCGCTGGCCGCCCTGGTCACGCTGGCCGGGTGGCT
CGGCTATCGCTATACGTACGACACCGCGCTGGCCCGCCAGGCCGAGCGCGGCCAGGTGCAACTGCGCCTCTACGCCCAGG
CGCTGGAAAGCGAGCTGGCGCGCTACGACTACGTGCCGAGCCTGCTGTCGCTGGACGCGCGGATCGAAGGGCTGCTGCGC
GAGCCGGGCGATCCCGCGCACGTGGCGCAAGCCAATGCCTATCTGGCATCGCTGAACATCCGCGCCGGCACGCGCGTGGT
CTATGTGCTCGACGCCCGCGGCAAGGTGCTGGCAACGAGCAACTACCAGCGCCCCGACAGCTACCTGGGCGAAGACCTGA
GCTTCCGCCCCTATTTCCGCACGGCCATCGACGGCCAGCTCGGGCGCTTCTACGGCGTGGGCACCACGCGCAGCGAATCC
GGCTACTACCTGTCCGCGCCGCTCGGCGACCGTGACCGGCCTCAGGGCGTGGCCGTGGTCAAGATCGGCCTCGAACCGCT
GGAGAACCGCTGGCAGGGCAACGACAGCCAGATGCTGCTGGCCGACGAGAATGGCGTCGTGATCCTGGCCTCCGATCCAT
CATGGAAGCTGGCCGCCTTGCGGCCGCTCTCCGCCGACCAACGCGCGAAGCTGGACCGCAGCCTGCAGTACAACCGCGCG
CCGTTGGCGCAACTGGAACTGTCCAAGGTCCGCGCGCTCGGCACCGGCCCGGCCGAGGGCGGCGACGCCCTGATGCGTCT
GCGCCAGGGCCCGCCAATGCTGGCCCAGCATCTGGCGCTGGCCGGCACGGACTGGAATCTCACTCTGCTCACCAACACCT
CGCAGGCACGCGTGGCAGCGCTCAACAGCGCCGCGCTGGAAGCAGCCAACAGCGAACTCGAGCGCAAGGTGGCCGAGCGC
ACCGCCGACCTGTCCGCCACCAACCAGCAGCTTCATGCCGAAGTGGCCGAACGGATCCGCACCGAGACAGTGTTGCGCCA
GGCCCAGGACGGCCTGATGCAGGCCGGCAAGCTCGCCGCCGTAGGCCAGATGTCGGCCGGCATCGCACACGAACTGAACC
AGCCCCTGACCGCGCTGCGCACGCTGTCCGGCAACACGGGCAAGTTCCTGGAACGCGGCGACTACGCGACGGTGCAGCAC
AACCTGGACAAGATCGTCGGACTGGTGGAGCGGATGGGTCGCATCACGGGCGCGCTCAAGTCGTTTGCCCGCAATCCATC
GGCCAGCCAGCGCAGTGTGGCGTATCTGGGCGACGCCGTTGAAAATGCGCTGTTCCTGCTGGAAACGCGTGTGGCGGCCG
TGGCGCCGCGCATCGAGCGCCAGATCGACGCGCGCCTGGCCGTGGCCTGCGATCCGAACCGCCTCGAACAGGTGCTGGTC
AACCTGATCGGCAATGCGCTCGACGCGCTGCGCGACCGCCCCGATCCCCTGCTGTCGTTGCACGCCTACGAAACCGGCGA
AAACGGCGGCATGGTGCATCTGACGGTGCGGGACAACGGCCCCGGCCTCTCCGAAGCCGCGTTCGCGAAGCTGTTCGAAC
CGTTCTTCACCACCAAACCCGCGGGCGAAGGGCTCGGCCTTGGGCTCACCCTGTCGGCCGGCATCCTCAACGAGAACGGC
GGCACCCTGACCGCGATCAATCACCCCGATGGCGGCGCCTGCTTCACGCTGGCGCTGCCGCAGGCGCGCGAGACACTTCG
CCATGTCGGCTAA

Upstream 100 bases:

>100_bases
AAATGCCTTATACAGCACTCATTGGCGCCCGTATCACCGATTCCGCATGATTGCCCCCCTTGAATCCATCCCCGTTCCCG
GCCAGTCCGAGGGCGGCGGT

Downstream 100 bases:

>100_bases
CCCGATCGAAGCGCCCCTGGACGCCGAGGCAACAAGCCCCGTGCTGACCGTGCTCATCGTCGAGGACGACGCCGACGTGC
GGCTCGGCTGCGAACAGGCG

Product: signal transduction histidine kinase regulating C4-dicarboxylate transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MPSPWRRVAPFVALLALAALVTLAGWLGYRYTYDTALARQAERGQVQLRLYAQALESELARYDYVPSLLSLDARIEGLLR
EPGDPAHVAQANAYLASLNIRAGTRVVYVLDARGKVLATSNYQRPDSYLGEDLSFRPYFRTAIDGQLGRFYGVGTTRSES
GYYLSAPLGDRDRPQGVAVVKIGLEPLENRWQGNDSQMLLADENGVVILASDPSWKLAALRPLSADQRAKLDRSLQYNRA
PLAQLELSKVRALGTGPAEGGDALMRLRQGPPMLAQHLALAGTDWNLTLLTNTSQARVAALNSAALEAANSELERKVAER
TADLSATNQQLHAEVAERIRTETVLRQAQDGLMQAGKLAAVGQMSAGIAHELNQPLTALRTLSGNTGKFLERGDYATVQH
NLDKIVGLVERMGRITGALKSFARNPSASQRSVAYLGDAVENALFLLETRVAAVAPRIERQIDARLAVACDPNRLEQVLV
NLIGNALDALRDRPDPLLSLHAYETGENGGMVHLTVRDNGPGLSEAAFAKLFEPFFTTKPAGEGLGLGLTLSAGILNENG
GTLTAINHPDGGACFTLALPQARETLRHVG

Sequences:

>Translated_590_residues
MPSPWRRVAPFVALLALAALVTLAGWLGYRYTYDTALARQAERGQVQLRLYAQALESELARYDYVPSLLSLDARIEGLLR
EPGDPAHVAQANAYLASLNIRAGTRVVYVLDARGKVLATSNYQRPDSYLGEDLSFRPYFRTAIDGQLGRFYGVGTTRSES
GYYLSAPLGDRDRPQGVAVVKIGLEPLENRWQGNDSQMLLADENGVVILASDPSWKLAALRPLSADQRAKLDRSLQYNRA
PLAQLELSKVRALGTGPAEGGDALMRLRQGPPMLAQHLALAGTDWNLTLLTNTSQARVAALNSAALEAANSELERKVAER
TADLSATNQQLHAEVAERIRTETVLRQAQDGLMQAGKLAAVGQMSAGIAHELNQPLTALRTLSGNTGKFLERGDYATVQH
NLDKIVGLVERMGRITGALKSFARNPSASQRSVAYLGDAVENALFLLETRVAAVAPRIERQIDARLAVACDPNRLEQVLV
NLIGNALDALRDRPDPLLSLHAYETGENGGMVHLTVRDNGPGLSEAAFAKLFEPFFTTKPAGEGLGLGLTLSAGILNENG
GTLTAINHPDGGACFTLALPQARETLRHVG
>Mature_589_residues
PSPWRRVAPFVALLALAALVTLAGWLGYRYTYDTALARQAERGQVQLRLYAQALESELARYDYVPSLLSLDARIEGLLRE
PGDPAHVAQANAYLASLNIRAGTRVVYVLDARGKVLATSNYQRPDSYLGEDLSFRPYFRTAIDGQLGRFYGVGTTRSESG
YYLSAPLGDRDRPQGVAVVKIGLEPLENRWQGNDSQMLLADENGVVILASDPSWKLAALRPLSADQRAKLDRSLQYNRAP
LAQLELSKVRALGTGPAEGGDALMRLRQGPPMLAQHLALAGTDWNLTLLTNTSQARVAALNSAALEAANSELERKVAERT
ADLSATNQQLHAEVAERIRTETVLRQAQDGLMQAGKLAAVGQMSAGIAHELNQPLTALRTLSGNTGKFLERGDYATVQHN
LDKIVGLVERMGRITGALKSFARNPSASQRSVAYLGDAVENALFLLETRVAAVAPRIERQIDARLAVACDPNRLEQVLVN
LIGNALDALRDRPDPLLSLHAYETGENGGMVHLTVRDNGPGLSEAAFAKLFEPFFTTKPAGEGLGLGLTLSAGILNENGG
TLTAINHPDGGACFTLALPQARETLRHVG

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=31.3653136531365, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87081816, Length=221, Percent_Identity=28.5067873303167, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786912, Length=116, Percent_Identity=37.9310344827586, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=29.4573643410853, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63690; Mature: 63559

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPWRRVAPFVALLALAALVTLAGWLGYRYTYDTALARQAERGQVQLRLYAQALESELA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEHHHHHHHHHHHHH
RYDYVPSLLSLDARIEGLLREPGDPAHVAQANAYLASLNIRAGTRVVYVLDARGKVLATS
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEEEECCCEEEEEEECCCCEEECC
NYQRPDSYLGEDLSFRPYFRTAIDGQLGRFYGVGTTRSESGYYLSAPLGDRDRPQGVAVV
CCCCCHHHHCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCCEEEE
KIGLEPLENRWQGNDSQMLLADENGVVILASDPSWKLAALRPLSADQRAKLDRSLQYNRA
EECCHHHHHHCCCCCCEEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCC
PLAQLELSKVRALGTGPAEGGDALMRLRQGPPMLAQHLALAGTDWNLTLLTNTSQARVAA
CHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHH
LNSAALEAANSELERKVAERTADLSATNQQLHAEVAERIRTETVLRQAQDGLMQAGKLAA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VGQMSAGIAHELNQPLTALRTLSGNTGKFLERGDYATVQHNLDKIVGLVERMGRITGALK
HHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SFARNPSASQRSVAYLGDAVENALFLLETRVAAVAPRIERQIDARLAVACDPNRLEQVLV
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHH
NLIGNALDALRDRPDPLLSLHAYETGENGGMVHLTVRDNGPGLSEAAFAKLFEPFFTTKP
HHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
AGEGLGLGLTLSAGILNENGGTLTAINHPDGGACFTLALPQARETLRHVG
CCCCCCEEEEEEECEEECCCCEEEEEECCCCCEEEEEECHHHHHHHHHCC
>Mature Secondary Structure 
PSPWRRVAPFVALLALAALVTLAGWLGYRYTYDTALARQAERGQVQLRLYAQALESELA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEHHHHHHHHHHHHH
RYDYVPSLLSLDARIEGLLREPGDPAHVAQANAYLASLNIRAGTRVVYVLDARGKVLATS
HHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEEEEECCCEEEEEEECCCCEEECC
NYQRPDSYLGEDLSFRPYFRTAIDGQLGRFYGVGTTRSESGYYLSAPLGDRDRPQGVAVV
CCCCCHHHHCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCCEEEE
KIGLEPLENRWQGNDSQMLLADENGVVILASDPSWKLAALRPLSADQRAKLDRSLQYNRA
EECCHHHHHHCCCCCCEEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHCCCCCC
PLAQLELSKVRALGTGPAEGGDALMRLRQGPPMLAQHLALAGTDWNLTLLTNTSQARVAA
CHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHH
LNSAALEAANSELERKVAERTADLSATNQQLHAEVAERIRTETVLRQAQDGLMQAGKLAA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VGQMSAGIAHELNQPLTALRTLSGNTGKFLERGDYATVQHNLDKIVGLVERMGRITGALK
HHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SFARNPSASQRSVAYLGDAVENALFLLETRVAAVAPRIERQIDARLAVACDPNRLEQVLV
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHH
NLIGNALDALRDRPDPLLSLHAYETGENGGMVHLTVRDNGPGLSEAAFAKLFEPFFTTKP
HHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
AGEGLGLGLTLSAGILNENGGTLTAINHPDGGACFTLALPQARETLRHVG
CCCCCCEEEEEEECEEECCCCEEEEEECCCCCEEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]