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The map label for this gene is ttuD [H]

Identifier: 94309350

GI number: 94309350

Start: 432487

End: 433785

Strand: Direct

Name: ttuD [H]

Synonym: Rmet_0405

Alternate gene names: 94309350

Gene position: 432487-433785 (Clockwise)

Preceding gene: 94309349

Following gene: 94309351

Centisome position: 11.01

GC content: 68.75

Gene sequence:

>1299_bases
GTGAATCCACAGGTCGATCCCCGTACATTGCTGCTGGAGAGCTTCCGCGCCGCCGTGGCGGCAGCCGATCCGCTCGAAAT
CGTGGCCGCGCACCTGCCGCCACCGCACGCGGGCGGCCGCACGCTGGTCGTTGGGGCAGGCAAGGCCGCGGCGTCAATGG
CGCTGGCCGTCGAACGCGCGTACCAGGGCAAGGCCAAACTGGAAGGCATCGTCGTCACGCGCTATGCGCACGGCCTGCCG
ACCGAACATATCCGCGTGATCGAAGCCGGCCATCCCGTGCCGGACGAGGCCGGCGAGCAGGCCGCCGCCGACATCCTTGC
CCGCGTGCAGGCGCTGGGCCCGGATGACCGGCTGATCGTGCTGGTCTCCGGCGGCGGGTCGAGCCTGCTGTCGTTGCCGG
CCGAAGGCATTCCCATGGCCGACCTCAAGGCCACCACGCGCGAGCTGCTGCGGTGCGGGGCGCCGATCACGGACATGAAT
ATCGTGCGCAAGCACACCTCGCGCATCCAGGGCGGCCGTCTGGCGCAGGCCAGCCGCGCCCCAGTCACCACGCTGATCGT
CTCGGACGTGGCCGGCGACGACCCGAGCGCGATTGCATCGGGTCCGACCGTGCCGGACGCAAGCACGTACGCCGATGCGC
TGGCGATCCTCAAGCGCTATGGCGCGGCGGTGCCGGCAACCGTGCAGGCGCATCTGGAGCGCGGCGCGCGTGGCGAGGTC
GAGGAAACGCCGAAGCCGGGCGATCCGCTGTTCATGAACGTGGACAATCGCATGATCGCCACGGCACACGACAGCCTGGA
AGCCGCGGCGGCTGAGTTCCGTCGCCAGGGCGTCAATGCGGTAGTGCTCGGCGATACCGTGACTGGCGAGGCGCAGGAGG
TGGCCCGCGTCTACGCGGCGCTGGTGCGCGAGATTCGAGCGTACAATGCGCCGTTCGCAGCGCCGGTTGCGCTGATTTCT
GGCGGTGAATGCACGGTCACATTGCCAAGCGGCGCGTCCGAATCGGCGCGCGGCGGGCGGTGCTCTGAATTCCTGCTGTC
TCTGGCGATCGAATTGGCAGGCACGCCGAATGTCCACGCGATCGCGGCCGATACCGACGGTATCGACGGGTCCGAAGACA
ATGCCGGCGCGTTGCTGGCGCCCGATTCGCTGGCCCGCGCGGAAGGCAGCGGCACTTCGGCCCGGCAGAAGCTCGACGCA
CACGACGCGTGGGGCTTTTTCGATGCGATCGGCGACCTGGTCGTGACCGGCCCGACGCGTACCAATGTGAATGACTACCG
CGCCATTCTGATTCTCTAG

Upstream 100 bases:

>100_bases
AGCAGGTGCTGGCCGCGGGACCGGGTCATGCGCCGCTGACGCGTGATATTGGCGGTACCGCCTCCACGGCCGATCTCGGC
CAGGCCATCGCGGAGGCGCT

Downstream 100 bases:

>100_bases
ATTTCCCCGTCTTACTCGTTTCGCTCGTCCCCATGACCCAGAAACTCACCATCACCCGCCCGGACGACTGGCACCTGCAC
CTGCGCGATGGCGCGGCGCT

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MNPQVDPRTLLLESFRAAVAAADPLEIVAAHLPPPHAGGRTLVVGAGKAAASMALAVERAYQGKAKLEGIVVTRYAHGLP
TEHIRVIEAGHPVPDEAGEQAAADILARVQALGPDDRLIVLVSGGGSSLLSLPAEGIPMADLKATTRELLRCGAPITDMN
IVRKHTSRIQGGRLAQASRAPVTTLIVSDVAGDDPSAIASGPTVPDASTYADALAILKRYGAAVPATVQAHLERGARGEV
EETPKPGDPLFMNVDNRMIATAHDSLEAAAAEFRRQGVNAVVLGDTVTGEAQEVARVYAALVREIRAYNAPFAAPVALIS
GGECTVTLPSGASESARGGRCSEFLLSLAIELAGTPNVHAIAADTDGIDGSEDNAGALLAPDSLARAEGSGTSARQKLDA
HDAWGFFDAIGDLVVTGPTRTNVNDYRAILIL

Sequences:

>Translated_432_residues
MNPQVDPRTLLLESFRAAVAAADPLEIVAAHLPPPHAGGRTLVVGAGKAAASMALAVERAYQGKAKLEGIVVTRYAHGLP
TEHIRVIEAGHPVPDEAGEQAAADILARVQALGPDDRLIVLVSGGGSSLLSLPAEGIPMADLKATTRELLRCGAPITDMN
IVRKHTSRIQGGRLAQASRAPVTTLIVSDVAGDDPSAIASGPTVPDASTYADALAILKRYGAAVPATVQAHLERGARGEV
EETPKPGDPLFMNVDNRMIATAHDSLEAAAAEFRRQGVNAVVLGDTVTGEAQEVARVYAALVREIRAYNAPFAAPVALIS
GGECTVTLPSGASESARGGRCSEFLLSLAIELAGTPNVHAIAADTDGIDGSEDNAGALLAPDSLARAEGSGTSARQKLDA
HDAWGFFDAIGDLVVTGPTRTNVNDYRAILIL
>Mature_432_residues
MNPQVDPRTLLLESFRAAVAAADPLEIVAAHLPPPHAGGRTLVVGAGKAAASMALAVERAYQGKAKLEGIVVTRYAHGLP
TEHIRVIEAGHPVPDEAGEQAAADILARVQALGPDDRLIVLVSGGGSSLLSLPAEGIPMADLKATTRELLRCGAPITDMN
IVRKHTSRIQGGRLAQASRAPVTTLIVSDVAGDDPSAIASGPTVPDASTYADALAILKRYGAAVPATVQAHLERGARGEV
EETPKPGDPLFMNVDNRMIATAHDSLEAAAAEFRRQGVNAVVLGDTVTGEAQEVARVYAALVREIRAYNAPFAAPVALIS
GGECTVTLPSGASESARGGRCSEFLLSLAIELAGTPNVHAIAADTDGIDGSEDNAGALLAPDSLARAEGSGTSARQKLDA
HDAWGFFDAIGDLVVTGPTRTNVNDYRAILIL

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=451, Percent_Identity=31.2638580931264, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI193205461, Length=452, Percent_Identity=26.5486725663717, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19920578, Length=441, Percent_Identity=28.3446712018141, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44593; Mature: 44593

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQVDPRTLLLESFRAAVAAADPLEIVAAHLPPPHAGGRTLVVGAGKAAASMALAVERA
CCCCCCHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHH
YQGKAKLEGIVVTRYAHGLPTEHIRVIEAGHPVPDEAGEQAAADILARVQALGPDDRLIV
HCCCCHHCEEEEEEECCCCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
LVSGGGSSLLSLPAEGIPMADLKATTRELLRCGAPITDMNIVRKHTSRIQGGRLAQASRA
EEECCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
PVTTLIVSDVAGDDPSAIASGPTVPDASTYADALAILKRYGAAVPATVQAHLERGARGEV
CEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
EETPKPGDPLFMNVDNRMIATAHDSLEAAAAEFRRQGVNAVVLGDTVTGEAQEVARVYAA
CCCCCCCCCEEEECCCCEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
LVREIRAYNAPFAAPVALISGGECTVTLPSGASESARGGRCSEFLLSLAIELAGTPNVHA
HHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
IAADTDGIDGSEDNAGALLAPDSLARAEGSGTSARQKLDAHDAWGFFDAIGDLVVTGPTR
EEECCCCCCCCCCCCCEEECCHHHHHCCCCCCHHHHHHCCHHHHHHHHHHCCEEEECCCC
TNVNDYRAILIL
CCCCCEEEEEEC
>Mature Secondary Structure
MNPQVDPRTLLLESFRAAVAAADPLEIVAAHLPPPHAGGRTLVVGAGKAAASMALAVERA
CCCCCCHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHH
YQGKAKLEGIVVTRYAHGLPTEHIRVIEAGHPVPDEAGEQAAADILARVQALGPDDRLIV
HCCCCHHCEEEEEEECCCCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
LVSGGGSSLLSLPAEGIPMADLKATTRELLRCGAPITDMNIVRKHTSRIQGGRLAQASRA
EEECCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
PVTTLIVSDVAGDDPSAIASGPTVPDASTYADALAILKRYGAAVPATVQAHLERGARGEV
CEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
EETPKPGDPLFMNVDNRMIATAHDSLEAAAAEFRRQGVNAVVLGDTVTGEAQEVARVYAA
CCCCCCCCCEEEECCCCEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
LVREIRAYNAPFAAPVALISGGECTVTLPSGASESARGGRCSEFLLSLAIELAGTPNVHA
HHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEE
IAADTDGIDGSEDNAGALLAPDSLARAEGSGTSARQKLDAHDAWGFFDAIGDLVVTGPTR
EEECCCCCCCCCCCCCEEECCHHHHHCCCCCCHHHHHHCCHHHHHHHHHHCCEEEECCCC
TNVNDYRAILIL
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]